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Emerging Microbes & Infections Volume 11, 2022 - Issue 1
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Research Article

Development and evaluation of a multi-epitope subunit vaccine against group B Streptococcus infection

Yumin Zhanga College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People’s Republic of China;b OIE Reference Lab for Swine Streptococcosis, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People's Republic of China;c Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People's Republic of China;d Key Laboratory of Animal Bacteriology, Ministry of Agriculture, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People's Republic of ChinaView further author information
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Song Lianga College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People’s Republic of China;b OIE Reference Lab for Swine Streptococcosis, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People's Republic of China;c Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People's Republic of China;d Key Laboratory of Animal Bacteriology, Ministry of Agriculture, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People's Republic of ChinaView further author information
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Shiyu Zhanga College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People’s Republic of China;b OIE Reference Lab for Swine Streptococcosis, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People's Republic of China;c Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People's Republic of China;d Key Laboratory of Animal Bacteriology, Ministry of Agriculture, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People's Republic of ChinaView further author information
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Shidan Zhanga College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People’s Republic of China;b OIE Reference Lab for Swine Streptococcosis, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People's Republic of China;c Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People's Republic of China;d Key Laboratory of Animal Bacteriology, Ministry of Agriculture, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People's Republic of ChinaView further author information
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Yong Yua College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People’s Republic of China;b OIE Reference Lab for Swine Streptococcosis, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People's Republic of China;c Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People's Republic of China;d Key Laboratory of Animal Bacteriology, Ministry of Agriculture, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People's Republic of ChinaView further author information
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Huochun Yaoa College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People’s Republic of China;b OIE Reference Lab for Swine Streptococcosis, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People's Republic of China;c Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People's Republic of China;d Key Laboratory of Animal Bacteriology, Ministry of Agriculture, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People's Republic of ChinaORCID Iconhttps://orcid.org/0000-0002-3749-8557View further author information
ORCID Icon,
Yongjie Liua College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People’s Republic of China;c Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People's Republic of China;d Key Laboratory of Animal Bacteriology, Ministry of Agriculture, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People's Republic of ChinaView further author information
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Wei Zhanga College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People’s Republic of China;b OIE Reference Lab for Swine Streptococcosis, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People's Republic of China;c Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People's Republic of China;d Key Laboratory of Animal Bacteriology, Ministry of Agriculture, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People's Republic of China;e Sanya Institute of Nanjing Agricultural University, Nanjing Agricultural University, Sanya, People’s Republic of ChinaView further author information
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Guangjin Liua College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People’s Republic of China;b OIE Reference Lab for Swine Streptococcosis, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People's Republic of China;c Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People's Republic of China;d Key Laboratory of Animal Bacteriology, Ministry of Agriculture, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People's Republic of China;e Sanya Institute of Nanjing Agricultural University, Nanjing Agricultural University, Sanya, People’s Republic of ChinaCorrespondence[email protected]
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Pages 2371-2382 | Received 19 Jul 2022, Accepted 04 Sep 2022, Published online: 29 Sep 2022

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Shiyang Ma, Fei Zhu, Yizhong Xu, Haicheng Wen, Mingjun Rao, Peipei Zhang, Wenzhong Peng, Yanhui Cui, Hang Yang, Caixia Tan, Jie Chen & Pinhua Pan. (2024) Development of a novel multi-epitope mRNA vaccine candidate to combat HMPV virus. Human Vaccines & Immunotherapeutics 20:1.
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Articles from other publishers (7)

Song Liang, Shidan Zhang, Yinli Bao, Yumin Zhang, Xinyi Liu, Huochun Yao & Guangjin Liu. (2024) Combined Immunoinformatics to Design and Evaluate a Multi-Epitope Vaccine Candidate against Streptococcus suis Infection. Vaccines 12:2, pages 137.
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Juan Mosqueda, Diego Josimar Hernández-Silva, Marco Antonio Vega-López, Lineth J. Vega-Rojas, Rolando Beltrán, Andrés Velasco-Elizondo, María del Carmen Ramírez-Estudillo, Mario Fragoso-Saavedra, Chyntia Pérez-Almeida, Jesús Hernández, Edgar A. Melgoza-González, Diana Hinojosa-Trujillo, Miguel Ángel Mercado-Uriostegui, Alma Susana Mejía-López, Carlos Rivera-Ballesteros & Teresa García-Gasca. (2023) Evaluation of the humoral and mucosal immune response of a multiepitope vaccine against COVID-19 in pigs. Frontiers in Immunology 14.
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Guihua Zhang, Lejiabao Han, Yuying Zhao, Quan Li, Shifeng Wang & Huoying Shi. (2023) Development and evaluation of a multi-epitope subunit vaccine against Mycoplasma synoviae infection. International Journal of Biological Macromolecules 253, pages 126685.
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Manu Kupani, Rajeev Kumar Pandey, Sharad Vashisht, Satyendra Singh, Vijay Kumar Prajapati & Sanjana Mehrotra. (2023) Prediction of an immunogenic peptide ensemble and multi-subunit vaccine for Visceral leishmaniasis using bioinformatics approaches. Heliyon 9:12, pages e22121.
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Mona Shafaghi, Zohreh Bahadori, Seyed Mahmoud Barzi, Elnaz Afshari, Hamid Madanchi, Seyed Fazlollah Mousavi & Ali Akbar Shabani. (2023) A new candidate epitope-based vaccine against PspA PhtD of Streptococcus pneumoniae: a computational experimental approach. Frontiers in Cellular and Infection Microbiology 13.
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Xin-Rong He, Yang Yang, Ye-Xin Chen, Shuai Kang, Fa-Jie Li, Dong-Xiao Li, Qing-Mei Liu, Gui-Xia Chen, Xiao-Mei Chen & Guang-Ming Liu. (2023) Immunoglobulin E Epitope Mapping and Structure–Allergenicity Relationship Analysis of Crab Allergen Scy p 9. Journal of Agricultural and Food Chemistry.
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Zhixia Wang, Wenyuan Pu, Qi Liu, Meifeng Zhu, Qinlei Chen, Yingchun Xu & Chunxiang Zhou. (2022) Association of Gut Microbiota Composition in Pregnant Women Colonized with Group B Streptococcus with Maternal Blood Routine and Neonatal Blood-Gas Analysis. Pathogens 11:11, pages 1297.
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