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(RG) Obstetrics and Gynaecology

A pharmacokinetic study with a low-dose oral contraceptive containing 20 μg ethinylestradiol plus 100 μg levonorgestrel

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Pages 79-90 | Published online: 06 Jul 2009

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Víctor M. Alfaro-Magallanes, Nuria Romero-Parra, Laura Barba-Moreno, Beatriz Rael, Pedro J. Benito, Ángel E. Díaz, Rocío Cupeiro & Ana B. Peinado. (2023) Serum iron availability, but not iron stores, is lower in naturally menstruating than in oral contraceptive athletes. European Journal of Sport Science 23:2, pages 231-240.
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Eliane A. Castro, Beatriz Rael, Nuria Romero-Parra, Víctor M. Alfaro-Magallanes, Miguel A. Rojo-Tirado, Antonio García-de-Alcaraz, Rocío Cupeiro & Ana B. Peinado. (2022) Influence of oral contraceptive phase on cardiorespiratory response to exercise in endurance-trained athletes. The European Journal of Contraception & Reproductive Health Care 27:4, pages 308-316.
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Birte Maria Hofmann, Dan Apter, Johannes Bitzer, Isabel Reinecke, Marco Serrani, Joachim Höchel & Martin Merz. (2020) Comparative pharmacokinetic analysis of levonorgestrel-releasing intrauterine systems and levonorgestrel-containing contraceptives with oral or subdermal administration route. The European Journal of Contraception & Reproductive Health Care 25:6, pages 417-426.
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Donald R. Mattison, Nataliya Karyakina, Michael Goodman & Judy S. LaKind. (2014) Pharmaco- and toxicokinetics of selected exogenous and endogenous estrogens: A review of the data and identification of knowledge gaps. Critical Reviews in Toxicology 44:8, pages 696-724.
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Franca Fruzzetti, Florence Trémollieres & Johannes Bitzer. (2012) An overview of the development of combined oral contraceptives containing estradiol: focus on estradiol valerate/dienogest. Gynecological Endocrinology 28:5, pages 400-408.
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Ying Su, Qing-Quan Lian & Ren-Shan Ge. (2012) Contraceptives with novel benefits. Expert Opinion on Investigational Drugs 21:1, pages 83-90.
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Jeffrey T Jensen & David F Archer. (2008) Evaluation of a continuous regimen of levonorgestrel/ethinyl estradiol for contraception and control of menstrual symptoms. Expert Opinion on Pharmacotherapy 9:2, pages 319-327.
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Paula Recacha-Ponce, Eladio Collado-Boira, Pilar Suarez-Alcazar, Macarena Montesinos-Ruiz & Carlos Hernando-Domingo. (2023) Is It Necessary to Adapt Training According to the Menstrual Cycle? Influence of Contraception and Physical Fitness Variables. Life 13:8, pages 1764.
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Kalinkina O.B., Tezikov Yu.V., Lipatov I.S. & Mayorova M.O.. (2022) RATIONAL APPROACH TO THE CHOICE OF INTRAUTERINE CONTRACEPTION. "Medical & pharmaceutical journal "Pulse", pages 15-20.
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E.V. Sheremetyeva & E.N. Andreeva. (2022) Individualized contraceptive counseling for young women in clinical practice. Problemy reproduktsii 28:4, pages 89.
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Belinda M. Thompson, Heidi L. Hillebrandt, Dean V. Sculley, Laura Barba-Moreno & Xanne A. K. Janse de Jonge. (2021) The acute effect of the menstrual cycle and oral contraceptive cycle on measures of body composition. European Journal of Applied Physiology 121:11, pages 3051-3059.
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Belinda M. Thompson, Kaitlyn B. Drover, Rhiannon J. Stellmaker, Dean V. Sculley & Xanne A. K. Janse de Jonge. (2021) The Effect of the Menstrual Cycle and Oral Contraceptive Cycle on Muscle Performance and Perceptual Measures. International Journal of Environmental Research and Public Health 18:20, pages 10565.
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Kirsty J. Elliott-Sale, Clare L. Minahan, Xanne A. K. Janse de Jonge, Kathryn E. Ackerman, Sarianna Sipilä, Naama W. Constantini, Constance M. Lebrun & Anthony C. Hackney. (2021) Methodological Considerations for Studies in Sport and Exercise Science with Women as Participants: A Working Guide for Standards of Practice for Research on Women. Sports Medicine 51:5, pages 843-861.
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Víctor M. Alfaro‐Magallanes, Laura Barba‐Moreno, Beatriz Rael, Nuria Romero‐Parra, Miguel A. Rojo‐Tirado, Pedro J. Benito, Dorine W. Swinkels, Coby M. Laarakkers, Ángel E. Díaz & Ana B. Peinado. (2020) Hepcidin response to interval running exercise is not affected by oral contraceptive phase in endurance‐trained women. Scandinavian Journal of Medicine & Science in Sports 31:3, pages 643-652.
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Leila Nejatbakhsh Samimi, Morteza Fallahpour, Majid Khoshmirsafa, Seyed Ali Javad Moosavi, Paria Bayati, Rasoul Baharlou & Reza Falak. (2020) The impact of 17β-estradiol and progesterone therapy on peripheral blood mononuclear cells of asthmatic patients. Molecular Biology Reports 48:1, pages 297-306.
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Charlotte Ginstman, Helena Kopp Kallner, Johanna Fagerberg-Silwer, Björn Carlsson, Andreas Ärlemalm, Ylva Böttiger & Jan Brynhildsen. (2020) Pharmacokinetics of Oral Levonorgestrel in Women After Roux-en-Y Gastric Bypass Surgery and in BMI-Matched Controls. Obesity Surgery 30:6, pages 2217-2224.
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Alexandra Ycaza Herrera, Sophia Faude, Shawn E. Nielsen, Mallory Locke & Mara Mather. (2019) Effects of hormonal contraceptive phase and progestin generation on stress-induced cortisol and progesterone release. Neurobiology of Stress 10, pages 100151.
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Isabel Reinecke, Birte Hofmann, Emir Mesic, Henk‐Jan Drenth & Dirk Garmann. (2018) An Integrated Population Pharmacokinetic Analysis to Characterize Levonorgestrel Pharmacokinetics After Different Administration Routes. The Journal of Clinical Pharmacology 58:12, pages 1639-1654.
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G. B. Dikke. (2017) Failure from the previously selected method of contraception and strategy for improving commitment. Problemy reproduktsii 23:5, pages 54.
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Elena Andreeva, Dar’y Sokolova & Ol'ga Grigoryan. (2016) Contraception in obese women. Obesity and metabolism 13:3, pages 65-69.
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Dan Apter, Kristina Gemzell-Danielsson, Brian Hauck, Kimberly Rosen & Christian Zurth. (2014) Pharmacokinetics of two low-dose levonorgestrel-releasing intrauterine systems and effects on ovulation rate and cervical function: pooled analyses of phase II and III studies. Fertility and Sterility 101:6, pages 1656-1662.e4.
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Stefano Lello & Andrea Cavani. (2014) Ethynilestradiol 20 mcg plus Levonorgestrel 100 mcg: Clinical Pharmacology. International Journal of Endocrinology 2014, pages 1-9.
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Y. Zimmerman, M. J. C. Eijkemans, H. J. T. Coelingh Bennink, M. A. Blankenstein & B. C. J. M. Fauser. (2013) The effect of combined oral contraception on testosterone levels in healthy women: a systematic review and meta-analysis. Human Reproduction Update 20:1, pages 76-105.
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Carolyn L. Westhoff, Kelsey A. Petrie & Serge Cremers. (2013) Using changes in binding globulins to assess oral contraceptive compliance. Contraception 87:2, pages 176-181.
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Regine Sitruk-Ware & Anita Nath. (2013) Characteristics and metabolic effects of estrogen and progestins contained in oral contraceptive pills. Best Practice & Research Clinical Endocrinology & Metabolism 27:1, pages 13-24.
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A. L. Oropesa, L. Guimarães, A. Martins, F. Soler & L. Guilhermino. (2011) RETRACTED ARTICLE: Acute and chronic toxicity of the pharmaceutical levonorgestrel to the freshwater crustacean Daphnia magna. Ecotoxicology 21:5, pages 1582-1582.
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David F. Archer, Frank Z. Stanczyk, Arkady Rubin & Marie Foegh. (2012) Ethinyl estradiol and levonorgestrel pharmacokinetics with a low-dose transdermal contraceptive delivery system, AG200-15: a randomized controlled trial. Contraception 85:6, pages 595-601.
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Charles E. DiLiberti, Christine M. O'Leary, Christopher H. Hendy, Donald H. Waters & Marya B. Margolis. (2011) Steady-state pharmacokinetics of an extended-regimen oral contraceptive with continuous estrogen. Contraception 83:1, pages 55-61.
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Morgan A. Marks, Patti E. Gravitt, Robert D. Burk, Yevgeniy Studentsov, Homayoon Farzadegan & Sabra L. Klein. (2010) Progesterone and 17β-Estradiol Enhance Regulatory Responses to Human Papillomavirus Type 16 Virus-Like Particles in Peripheral Blood Mononuclear Cells from Healthy Women. Clinical and Vaccine Immunology 17:4, pages 609-617.
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Jerker Fick, Richard H. Lindberg, Jari Parkkonen, Björn Arvidsson, Mats Tysklind & D. G. Joakim Larsson. (2010) Therapeutic Levels of Levonorgestrel Detected in Blood Plasma of Fish: Results from Screening Rainbow Trout Exposed to Treated Sewage Effluents. Environmental Science & Technology 44:7, pages 2661-2666.
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Britta N. Torgrimson, Jessica R. Meendering, Paul F. Kaplan & Christopher T. Minson. (2007) Endothelial function across an oral contraceptive cycle in women using levonorgestrel and ethinyl estradiol. American Journal of Physiology-Heart and Circulatory Physiology 292:6, pages H2874-H2880.
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Gemma D. Bishop & Margaret D. Brown. (2007) Cutaneous postural vasoconstriction is modified by exogenous but not endogenous female hormones in young women. Clinical Autonomic Research 17:2, pages 85-92.
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Rolf Terlinden, Heinz Uragg, Karin Göhler & Christa Kneip. (2006) Pharmacokinetics of chlormadinone acetate following single and multiple oral dosing of chlormadinone acetate (2 mg) and ethinylestradiol (0.03 mg) and elimination and clearance of a single dose of radiolabeled chlormadinone acetate. Contraception 74:3, pages 239-244.
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