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Artificial Cells, Blood Substitutes, and Biotechnology Volume 30, 2002 - Issue 3
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Original

CALCULATIONS OF OXYGEN TRANSPORT BY RED BLOOD CELLS AND HEMOGLOBIN SOLUTIONS IN CAPILLARIES

Arjun Vadapalli Department of Biomedical Engineering and Center for Computational Medicine and Biology, School of Medicine, John Hopkins University, Baltimore, MD, 21205, U.S.A.
,
Daniel Goldman Department of Mathematical Sciences, New Jersey Institute of Technology, Newark, NJ, 07102, U.S.A.
&
Aleksander S. Popel Department of Biomedical Engineering and Center for Computational Medicine and Biology, School of Medicine, John Hopkins University, Baltimore, MD, 21205, U.S.A.
Pages 157-188 | Published online: 11 Jul 2009

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Qiming Zhang, Natsuko F. Inagaki & Taichi Ito. (2023) Recent advances in micro-sized oxygen carriers inspired by red blood cells. Science and Technology of Advanced Materials 24:1.
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Daniel Goldman. (2008) Theoretical Models of Microvascular Oxygen Transport to Tissue. Microcirculation 15:8, pages 795-811.
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NIKOLAOS M. TSOUKIAS & ALEKSANDER S. POPEL. (2003) A Model of Nitric Oxide Capillary Exchange. Microcirculation 10:6, pages 479-495.
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Ion Udroiu. (2023) Phylogeny and evolution of erythrocytes in mammals. Journal of Experimental Biology 226:11.
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Farhad A. Amiri & Junfeng Zhang. (2023) Tissue Oxygenation Around Capillaries: Effects of Hematocrit and Arteriole Oxygen Condition. Bulletin of Mathematical Biology 85:6.
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Farhad A. Amiri & Junfeng Zhang. (2023) Oxygen transport across tank-treading red blood cell: Individual and joint roles of flow convection and oxygen-hemoglobin reaction. Microvascular Research 145, pages 104447.
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D. Picchi & P. Poesio. (2022) Dispersion of a passive scalar around a Taylor bubble. Journal of Fluid Mechanics 951.
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Rachid Chebbi. (2022) An analytical model for solute transport from blood to tissue. Open Physics 20:1, pages 249-258.
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Keith Christian Afas & Daniel Goldman. (2022) A two-layer continuously distributed capillary O2 transport model applied to blood flow regulation in resting skeletal muscle. Journal of Theoretical Biology 539, pages 111058.
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Farhad A. Amiri & Junfeng Zhang. (2021) An immersed membrane method for mass transfer across flexible semipermeable membranes in flows. International Communications in Heat and Mass Transfer 128, pages 105601.
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Jessica S. Yu & Neda Bagheri. (2021) Modular microenvironment components reproduce vascular dynamics de novo in a multi-scale agent-based model. Cell Systems 12:8, pages 795-809.e9.
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Kevin Ziyang Chng, Yan Cheng Ng, Bumseok Namgung, Justin Kok Soon Tan, Soyeon Park, Sim Leng Tien, Hwa Liang Leo & Sangho Kim. (2021) Assessment of transient changes in oxygen diffusion of single red blood cells using a microfluidic analytical platform. Communications Biology 4:1.
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Keith C. Afas, Raashi Vijay & Daniel Goldman. (2021) A two-compartment model of oxygen transport in skeletal muscle using continuously distributed capillaries. Mathematical Biosciences 333, pages 108535.
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Donald A. Belcher, Alfredo Lucas, Pedro Cabrales & Andre F. Palmer. (2020) Tumor vascular status controls oxygen delivery facilitated by infused polymerized hemoglobins with varying oxygen affinity. PLOS Computational Biology 16:8, pages e1008157.
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Toru Hyakutake & Takumi Kishimoto. (2017) Numerical investigation of oxygen transport by hemoglobin-based carriers through microvessels. Journal of Artificial Organs 20:4, pages 341-349.
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Adrien Lücker, Timothy W. Secomb, Bruno Weber & Patrick Jenny. (2017) The relative influence of hematocrit and red blood cell velocity on oxygen transport from capillaries to tissue. Microcirculation 24:3.
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Julia C. Arciero, Paola Causin & Francesca Malgaroli. (2017) Mathematical methods for modeling the microcirculation. AIMS Biophysics 4:3, pages 362-399.
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Sean McKee, Ewan A Dougall & Nigel J Mottram. (2016) Analytic solutions of a simple advection-diffusion model of an oxygen transfer device. Journal of Mathematics in Industry 6:1.
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Ufuk Olgac & Vartan Kurtcuoglu. (2016) The Bohr Effect Is Not a Likely Promoter of Renal Preglomerular Oxygen Shunting. Frontiers in Physiology 7.
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Connie C.W. Hsia, Dallas M. Hyde & Ewald R. Weibel. 2011. Comprehensive Physiology. Comprehensive Physiology 827 895 .
Ufuk OlgacVartan Kurtcuoglu. (2015) Renal oxygenation: preglomerular vasculature is an unlikely contributor to renal oxygen shunting. American Journal of Physiology-Renal Physiology 308:7, pages F671-F688.
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Hadi Tabesh, Ghasem Amoabediny, Ali Rasouli, Arash Ramedani, Ali Poorkhalil, Ali Kashefi & Khosrow Mottaghy. (2014) Simulation of blood oxygenation in capillary membrane oxygenators using modified sulfite solution. Biophysical Chemistry 195, pages 8-15.
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T.-W. Lee, K.-S. Bae, Heung S. Choi & Ming-Jyh Chern. (2014) Computational Simulations of Flow and Oxygen/Drug Delivery in a Three-Dimensional Capillary Network. ISRN Biomathematics 2014, pages 1-11.
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Daniel Ortiz, Marcelo Barros, Su Yan & Pedro Cabrales. (2014) Resuscitation from hemorrhagic shock using polymerized hemoglobin compared to blood. The American Journal of Emergency Medicine 32:3, pages 248-255.
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Raymond C. Koehler. 2013. Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics. Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics 435 453 .
Raymond C. Koehler. 2011. Chemistry and Biochemistry of Oxygen Therapeutics. Chemistry and Biochemistry of Oxygen Therapeutics 23 45 .
T.E. Moschandreou, C.G. Ellis & D. Goldman. (2011) Influence of tissue metabolism and capillary oxygen supply on arteriolar oxygen transport: A computational model. Mathematical Biosciences 232:1, pages 1-10.
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Tad Hogg & Robert A. FreitasJrJr. (2010) Chemical power for microscopic robots in capillaries. Nanomedicine: Nanotechnology, Biology and Medicine 6:2, pages 298-317.
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Xiaoqian Shan, Yuan Yuan, Changsheng Liu, Xinyi Tao, Yan Sheng & Feng Xu. (2009) Influence of PEG chain on the complement activation suppression and longevity in vivo prolongation of the PCL biomedical nanoparticles. Biomedical Microdevices 11:6, pages 1187-1194.
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Jan A. Plock, Nassim Rafatmehr, Dubravko Sinovcic, Jonas Schnider, Hiromi Sakai, Eishun Tsuchida, Andrej Banic & Dominique Erni. (2009) Hemoglobin vesicles improve wound healing and tissue survival in critically ischemic skin in mice. American Journal of Physiology-Heart and Circulatory Physiology 297:3, pages H905-H910.
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Sharon Irene Gundersen, Guo Chen & Andre Francis Palmer. (2009) Mathematical model of NO and O2 transport in an arteriole facilitated by hemoglobin based O2 carriers. Biophysical Chemistry 143:1-2, pages 1-17.
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Toshiaki MitoMasaaki NemotoHerman KwansaKenji SampeiMurtuza HabeebStephanie J. MurphyEnrico BucciRaymond C. Koehler. (2009) Decreased Damage From Transient Focal Cerebral Ischemia by Transfusion of Zero-Link Hemoglobin Polymers in Mouse. Stroke 40:1, pages 278-284.
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Russell Cole, Kim Vandegriff, Andrew Szeri, Omer Savas & Robert Winslow. (2008) Targeted O2 delivery by blood substitutes: in vitro arteriolar simulations of first- and second-generation products. Microvascular Research 76:3, pages 169-179.
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Sharon I. Gundersen & Andre F. Palmer. (2008) Hemoglobin‐based oxygen carrier enhanced tumor oxygenation: A novel strategy for cancer therapy. Biotechnology Progress 24:6, pages 1353-1364.
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C. Escobar & F. Méndez. (2008) Unloading oxygen in a capillary vessel under a pathological condition. Mathematical Biosciences 215:2, pages 127-136.
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Raymond C. Koehler, Clara Fronticelli & Enrico Bucci. (2008) Insensitivity of cerebral oxygen transport to oxygen affinity of hemoglobin-based oxygen carriers. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1784:10, pages 1387-1394.
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Nikolaos M. Tsoukias, Daniel Goldman, Arjun Vadapalli, Roland N. Pittman & Aleksander S. Popel. (2007) A computational model of oxygen delivery by hemoglobin-based oxygen carriers in three-dimensional microvascular networks. Journal of Theoretical Biology 248:4, pages 657-674.
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Sharon I. Gundersen & Andre F. Palmer. (2007) Conjugation of methoxypolyethylene glycol to the surface of bovine red blood cells. Biotechnology and Bioengineering 96:6, pages 1199-1210.
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Jan A. Plock, Annemarie E. Tromp, Claudio Contaldo, Timo Spanholtz, Dubravko Sinovcic, Hiromi Sakai, Eishun Tsuchida, Michael Leunig, Andrej Banic & Dominique Erni. (2007) Hemoglobin vesicles reduce hypoxia-related inflammation in critically ischemic hamster flap tissue. Critical Care Medicine 35:3, pages 899-905.
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Michael L. Dimino & Andre F. Palmer. (2007) Hemoglobin-Based O 2 Carrier O 2 Affinity and Capillary Inlet pO 2 Are Important Factors That Influence O 2 Transport in a Capillary . Biotechnology Progress 23:4, pages 921-931.
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James W. Ji, Nikolaos M. Tsoukias, Daniel Goldman & Aleksander S. Popel. (2006) A computational model of oxygen transport in skeletal muscle for sprouting and splitting modes of angiogenesis. Journal of Theoretical Biology 241:1, pages 94-108.
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Masaaki Nemoto, Toshiaki Mito, William S Brinigar, Clara Fronticelli & Raymond C. Koehler. (2006) Salvage of focal cerebral ischemic damage by transfusion of high O 2 -affinity recombinant hemoglobin polymers in mouse . Journal of Applied Physiology 100:5, pages 1688-1691.
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Jesse P. Sullivan & Andre F. Palmer. (2008) Targeted Oxygen Delivery within Hepatic Hollow Fiber Bioreactors via Supplementation of Hemoglobin-Based Oxygen Carriers. Biotechnology Progress 22:5, pages 1374-1387.
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Thomas C. Page & J. David Hellums. 2006. Blood Substitutes. Blood Substitutes 72 83 .
Jan A. Plock, Claudio Contaldo, Hiromi Sakai, Eishun Tsuchida, Michael Leunig, Andrej Banic, Michael D. Menger & Dominique Erni. (2005) Is hemoglobin in hemoglobin vesicles infused for isovolemic hemodilution necessary to improve oxygenation in critically ischemic hamster skin?. American Journal of Physiology-Heart and Circulatory Physiology 289:6, pages H2624-H2631.
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Claudio Contaldo, Jan Plock, Hiromi Sakai, Shinji Takeoka, Eishun Tsuchida, Michael Leunig, Andrej Banic & Dominique Erni. (2005) New generation of hemoglobin-based oxygen carriers evaluated for oxygenation of critically ischemic hamster flap tissue. Critical Care Medicine 33:4, pages 806-812.
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Aleksander S. Popel, Mahendra Kavdia & Nikolaos M. Tsoukias. 2005. Artificial Oxygen Carrier. Artificial Oxygen Carrier 176 185 .
Hiromi Sakai, Yoji Suzuki, Megumi Kinoshita, Shinji Takeoka, Nobuji Maeda & Eishun Tsuchida. (2003) O 2 release from Hb vesicles evaluated using an artificial, narrow O 2 -permeable tube: comparison with RBCs and acellular Hbs . American Journal of Physiology-Heart and Circulatory Physiology 285:6, pages H2543-H2551.
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NIKOLAOS M. TSOUKIAS & ALEKSANDER S. POPEL. (2010) A Model of Nitric Oxide Capillary Exchange. Microcirculation 10:6, pages 479-495.
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Claudio Contaldo, Sören Schramm, Reto Wettstein, Hiromi Sakai, Shinji Takeoka, Eishun Tsuchida, Michael Leunig, Andrej Banic & Dominique Erni. (2003) Improved oxygenation in ischemic hamster flap tissue is correlated with increasing hemodilution with Hb vesicles and their O 2 affinity . American Journal of Physiology-Heart and Circulatory Physiology 285:3, pages H1140-H1147.
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Kevin M. Bobofchak, Toshiaki Mito, Sarah J. Texel, Andrea Bellelli, Masaaki Nemoto, Richard J. Traystman, Raymond C. Koehler, William S. Brinigar & Clara Fronticelli. (2003) A recombinant polymeric hemoglobin with conformational, functional, and physiological characteristics of an in vivo O 2 transporter . American Journal of Physiology-Heart and Circulatory Physiology 285:2, pages H549-H561.
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Mahendra Kavdia, Roland N. Pittman & Aleksander S. Popel. (2002) Theoretical analysis of effects of blood substitute affinity and cooperativity on organ oxygen transport. Journal of Applied Physiology 93:6, pages 2122-2128.
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