Advanced search
Publication Cover
Journal of Toxicology: Clinical Toxicology Volume 39, 2001 - Issue 7
Journal homepage
190
Views
63
CrossRef citations to date
0
Altmetric
Research Article

Randomized Placebo-Controlled Trial of 2,3-Dimercapto-1-propanesulfonate (DMPS) in Therapy of Chronic Arsenicosis Due to Drinking Arsenic-Contaminated Water

Debendra Nath Guha Mazumder Department of Gastroenterology and Medicine, Institute of Postgraduate Medical Education and Research, Calcutta, India
,
Binay Krishna De Department of Gastroenterology and Medicine, Institute of Postgraduate Medical Education and Research, Calcutta, India
,
Amal Santra Department of Gastroenterology and Medicine, Institute of Postgraduate Medical Education and Research, Calcutta, India
,
Nilima Ghosh Department of Gastroenterology and Medicine, Institute of Postgraduate Medical Education and Research, Calcutta, India
,
Subhankar Das Department of Gastroenterology and Medicine, Institute of Postgraduate Medical Education and Research, Calcutta, India
,
Sarbari Lahiri Department of Gastroenterology and Medicine, Institute of Postgraduate Medical Education and Research, Calcutta, India
&
Tapas Das Department of Gastroenterology and Medicine, Institute of Postgraduate Medical Education and Research, Calcutta, India
 show all
Pages 665-674 | Published online: 31 Dec 2001

Citations (63)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (8)

Sanjib Bhattacharya. (2017) Medicinal plants and natural products in amelioration of arsenic toxicity: a short review. Pharmaceutical Biology 55:1, pages 349-354.
Read now
Aparajita Ghosh, Ardhendu K. Mandal, Sibani Sarkar & Nirmalendu Das. (2011) Hepatoprotective and neuroprotective activity of liposomal quercetin in combating chronic arsenic induced oxidative damage in liver and brain of rats. Drug Delivery 18:6, pages 451-459.
Read now
Aud-E. Stenehjem, Marie Vahter, Barbro Nermell, Jorulf Aasen, Syverin Lierhagen, Jørg Mørland & Dag Jacobsen. (2007) Slow recovery from severe inorganic arsenic poisoning despite treatment with DMSA (2.3-dimercaptosuccinic acid). Clinical Toxicology 45:4, pages 424-428.
Read now
SIMON KAPAJ, HANS PETERSON, KARSTEN LIBER & PROSUN BHATTACHARYA. (2006) Human Health Effects From Chronic Arsenic Poisoning–A Review. Journal of Environmental Science and Health, Part A 41:10, pages 2399-2428.
Read now
Barbara Vantroyen, J‐F. Heilier, Agnes Meulemans, Arnold Michels, J‐P. Buchet, Steven Vanderschueren, V. Haufroid & Marc Sabbe. (2004) Survival After a Lethal Dose of Arsenic Trioxide. Journal of Toxicology: Clinical Toxicology 42:6, pages 889-895.
Read now
S. J. S. Flora, G. M. Kannan, B. P. Pant & D. K. Jaiswal. (2003) The Efficacy of Monoisoamyl Ester of Dimercaptosuccinic Acid in Chronic Experimental Arsenic Poisoning in Mice. Journal of Environmental Science and Health, Part A 38:1, pages 241-254.
Read now
D. N. Guha Mazumder. (2003) Chronic Arsenic Toxicity: Clinical Features, Epidemiology, and Treatment: Experience in West Bengal. Journal of Environmental Science and Health, Part A 38:1, pages 141-163.
Read now
Mohammad Mahmudur Rahman, Uttam Kumar Chowdhury, Subhash Chandra Mukherjee, Badal Kumar Mondal, Kunal Paul, Dilip Lodh, Bhajan Kumar Biswas, Chitta Ranjan Chanda, Gautam Kumar Basu, Kshitish Chandra Saha, Shibtosh Roy, Ranajit Das, Shyamal Kanti Palit, Quazi Quamruzzaman & Dipankar Chakraborti. (2001) Chronic Arsenic Toxicity in Bangladesh and West Bengal, India—A Review and Commentary. Journal of Toxicology: Clinical Toxicology 39:7, pages 683-700.
Read now

Articles from other publishers (55)

Mersedeh Shayan, Samira Barangi, Hossein Hosseinzadeh & Soghra Mehri. (2023) The protective effect of natural or chemical compounds against arsenic-induced neurotoxicity: Cellular and molecular mechanisms. Food and Chemical Toxicology 175, pages 113691.
Crossref
Dominika A. Jegen & Paul J. Jannetto. (2023) What’s in your water? A well-known risk for arsenic toxicity. Journal of Rural Medicine 18:2, pages 149-153.
Crossref
D.N. Guha Mazumder. 2023. Handbook of Arsenic Toxicology. Handbook of Arsenic Toxicology 151 192 .
Manisha Thakur & Swaran Jeet Singh Flora. 2023. Handbook of Arsenic Toxicology. Handbook of Arsenic Toxicology 667 707 .
Smita Kumari, Sudhanshu Sharma, Dia Advani, Akanksha Khosla, Pravir Kumar & Rashmi K. Ambasta. (2021) Unboxing the molecular modalities of mutagens in cancer. Environmental Science and Pollution Research 29:41, pages 62111-62159.
Crossref
Md. Shiblur Rahaman, Nathan Mise & Sahoko Ichihara. (2022) Arsenic contamination in food chain in Bangladesh: A review on health hazards, socioeconomic impacts and implications. Hygiene and Environmental Health Advances 2, pages 100004.
Crossref
Seung-Hyun Ro, Jiyoung Bae, Yura Jang, Jacob F. Myers, Soonkyu Chung, Jiujiu Yu, Sathish Kumar Natarajan, Rodrigo Franco & Hyun-Seob Song. (2022) Arsenic Toxicity on Metabolism and Autophagy in Adipose and Muscle Tissues. Antioxidants 11:4, pages 689.
Crossref
Serap Bilge. 2022. Neurotoxicity - New Advances. Neurotoxicity - New Advances.
Patrice Delaney, Anjana Ramdas Nair, Catherine Palmer, Nouf Khan & Kirsten C. Sadler. (2020) Arsenic induced redox imbalance triggers the unfolded protein response in the liver of zebrafish. Toxicology and Applied Pharmacology 409, pages 115307.
Crossref
R. Garnier, E. Nouyrigat, P. Benoit, J.-P. Goullé, C. Granon, J. Manel, N. Manouchehri, A. Mathieu-Huart, P. Nisse, J.-C. Normand, S. Ronga-Pézeret, A. Roulet, F. Simon, P. Gabach, C. Tournoud, G. Augé, A. Barbillon, C. Boudet, M. Bourgeat, A. Droissart-Long, S. El Balkhi, N. Franchitto, M. Glaizal, P. Glorennec, E. Gnansia, V. Haufroid, J.-Y. Breurec, P. Cambier, P. Carlier, J. Carretier, D. Chanaud, A. Charrière, F. Clinard, O. Dereure, S. Kleinlogel, M. Labadie, R. Laporte, J.-F. Heilier, B. Javelaud, A. Lefranc, B. Lelièvre, D. Lucas, F. Marot, O. Mathieu, F. Nesslany, N. Nikolova-Pavageau, C. Nisse, K. Peronnet, E. Puskarczyk, P. Quénel, M.-C. Rauzier-Jaoul, H. Roussel, N. Sadeg, J.-M. Sapori, M.-P. Sauvant-Rochat, C. Verdun-Esquer, K. Veyer, A. Villa & S. Vircondelet. (2020) Dépistage, prise en charge et suivi des personnes potentiellement surexposées à l’arsenic inorganique du fait de leur lieu de résidence. Archives des Maladies Professionnelles et de l'Environnement 81:6, pages 770-796.
Crossref
Abhijnan BhatSubhas Chandra BhatDr.Dr.. (2020) ARSENIC POLLUTION AND REMEDIAL MEASURES IN WEST BENGAL: AN OVERVIEW. GLOBAL JOURNAL FOR RESEARCH ANALYSIS, pages 52-56.
Crossref
Geir Bjørklund, Petro Oliinyk, Roman Lysiuk, Md. Shiblur Rahaman, Halyna Antonyak, Iryna Lozynska, Larysa Lenchyk & Massimiliano Peana. (2020) Arsenic intoxication: general aspects and chelating agents. Archives of Toxicology 94:6, pages 1879-1897.
Crossref
Valeria M. Nurchi, Aleksandra Buha Djordjevic, Guido Crisponi, Jan Alexander, Geir Bjørklund & Jan Aaseth. (2020) Arsenic Toxicity: Molecular Targets and Therapeutic Agents. Biomolecules 10:2, pages 235.
Crossref
Geir Bjørklund, Torsak Tippairote, Md. Shiblur Rahaman & Jan Aaseth. (2019) Developmental toxicity of arsenic: a drift from the classical dose–response relationship. Archives of Toxicology 94:1, pages 67-75.
Crossref
Chun-Yuan Hsiao, Chip Gresham & Mark R. Marshall. (2019) Treatment of lead and arsenic poisoning in anuric patients – a case report and narrative review of the literature. BMC Nephrology 20:1.
Crossref
George Braitberg. 2019. Critical Care Nephrology. Critical Care Nephrology 574 588.e3 .
Yumi Abiko & Yoshito Kumagai. 2019. Arsenic Contamination in Asia. Arsenic Contamination in Asia 151 161 .
Mark Louis Siefring, Doanh Lu, J Christopher States & Minh Van Hoang. (2018) Rapid onset of multiple concurrent squamous cell carcinomas associated with the use of an arsenic-containing traditional medicine for chronic plaque psoriasis. BMJ Case Reports, pages bcr-2017-222645.
Crossref
Geir Bjørklund, Joachim Mutter & Jan Aaseth. (2017) Metal chelators and neurotoxicity: lead, mercury, and arsenic. Archives of Toxicology 91:12, pages 3787-3797.
Crossref
Chinthalapally V. Rao, Sanya Pal, Altaf Mohammed, Mudassir Farooqui, Mark P. Doescher, Adam S. Asch & Hiroshi Y. Yamada. (2017) Biological effects and epidemiological consequences of arsenic exposure, and reagents that can ameliorate arsenic damage in vivo . Oncotarget 8:34, pages 57605-57621.
Crossref
Paramita Mandal. (2017) Molecular insight of arsenic-induced carcinogenesis and its prevention. Naunyn-Schmiedeberg's Archives of Pharmacology 390:5, pages 443-455.
Crossref
Nilanjana Banerjee, Apurba K. Bandyopadhyay, Suman Dutta, Jayanta K. Das, Tarit Roy Chowdhury, Arun Bandyopadhyay & Ashok K. Giri. (2017) Increased microRNA 21 expression contributes to arsenic induced skin lesions, skin cancers and respiratory distress in chronically exposed individuals. Toxicology 378, pages 10-16.
Crossref
Michelle Pratt, Patricia Wadden & Wayne Gulliver. (2015) Arsenic Keratosis in a Patient from Newfoundland and Labrador, Canada. Journal of Cutaneous Medicine and Surgery 20:1, pages 67-71.
Crossref
Piyush Kumar, Rudrajit Paul, Amrita Sil & Nilay Das. 2015. Arsenic Toxicity. Arsenic Toxicity 401 428 .
Jan Aaseth, Marit Aralt Skaug, Yang Cao & Ole Andersen. (2015) Chelation in metal intoxication—Principles and paradigms. Journal of Trace Elements in Medicine and Biology 31, pages 260-266.
Crossref
NC Sumedha & S Miltonprabu. (2014) Diallyl trisulfide ameliorates arsenic-induced hepatotoxicity by abrogation of oxidative stress, inflammation, and apoptosis in rats. Human & Experimental Toxicology 34:5, pages 506-525.
Crossref
Govinder Flora, Megha Mittal & Swaran J.S. Flora. 2015. Handbook of Arsenic Toxicology. Handbook of Arsenic Toxicology 589 626 .
D.N. Guha Mazumder. 2015. Handbook of Arsenic Toxicology. Handbook of Arsenic Toxicology 137 177 .
Michael J Kosnett. (2013) The Role of Chelation in the Treatment of Arsenic and Mercury Poisoning. Journal of Medical Toxicology 9:4, pages 347-354.
Crossref
Somnath Paul, Pritha Bhattacharjee, Prafulla K. Mishra, Debmita Chatterjee, Anirban Biswas, Debasree Deb, Aloke Ghosh, D. N. Guha Mazumder & Ashok K. Giri. (2013) Human urothelial micronucleus assay to assess genotoxic recovery by reduction of arsenic in drinking water: a cohort study in West Bengal, India. BioMetals 26:5, pages 855-862.
Crossref
Somnath Paul, Nandana Das, Pritha Bhattacharjee, Mayukh Banerjee, Jayanta K Das, Nilendu Sarma, Ajoy Sarkar, Apurba K Bandyopadhyay, Tanmoy J Sau, Santanu Basu, Saptarshi Banerjee, Papia Majumder & Ashok K Giri. (2012) Arsenic-induced toxicity and carcinogenicity: a two-wave cross-sectional study in arsenicosis individuals in West Bengal, India. Journal of Exposure Science & Environmental Epidemiology 23:2, pages 156-162.
Crossref
Nikolay Matveev & Molly Kile. 2012. Dermatotoxicology, Eighth Edition. Dermatotoxicology, Eighth Edition 218 225 .
Klaus-Peter Wilhelm, Hongbo Zhai & Howard I. MaibachNikolay V. Matveev & Molly L. Kile. 2012. Dermatotoxicology. Dermatotoxicology 218 225 .
Sangita Majumdar, Anasuya Maiti, Subhra Karmakar, Asankur Sekhar Das, Sandip Mukherjee, Dolan Das & Chandan Mitra. (2012) Antiapoptotic efficacy of folic acid and vitamin B12 against arsenic-induced toxicity. Environmental Toxicology 27:6, pages 351-363.
Crossref
Michael A. Mcguigan. 2012. Goldman's Cecil Medicine. Goldman's Cecil Medicine 88 95 .
Sangita Majumdar, Subhra Karmakar, Anasuya Maiti, Monalisa Choudhury, Aniruddha Ghosh, Asankur Sekhar Das & Chandan Mitra. (2011) Arsenic-induced hepatic mitochondrial toxicity in rats and its amelioration by dietary phosphate. Environmental Toxicology and Pharmacology 31:1, pages 107-118.
Crossref
M J Kosnett. (2010) Chelation for Heavy Metals (Arsenic, Lead, and Mercury): Protective or Perilous?. Clinical Pharmacology & Therapeutics 88:3, pages 412-415.
Crossref
Tanmoy Rana, Asit Kumar Bera, Subhashree Das, Debasis Bhattacharya, Subhasish Bandyopadhyay, Diganta Pan & Subrata Kumar Das. (2010) Effect of chronic intake of arsenic-contaminated water on blood oxidative stress indices in cattle in an arsenic-affected zone. Ecotoxicology and Environmental Safety 73:6, pages 1327-1332.
Crossref
Abdul Momin. 2011. Climate Change and Food Security in South Asia. Climate Change and Food Security in South Asia 107 118 .
Nilanjana Banerjee, Saptarshi Banerjee, Rupashree Sen, Apurba Bandyopadhyay, Nilendu Sarma, Papiya Majumder, Jayanta K. Das, Mitali Chatterjee, Syed N. Kabir & Ashok K. Giri. (2009) Chronic Arsenic Exposure Impairs Macrophage Functions in the Exposed Individuals. Journal of Clinical Immunology 29:5, pages 582-594.
Crossref
Sangita Majumdar, Sandip Mukherjee, Anasuya Maiti, Subhra Karmakar, Asankur Sekhar Das, Maitrayee Mukherjee, Arunabha Nanda & Chandan Mitra. (2008) Folic acid or combination of folic acid and vitamin B 12 prevents short‐term arsenic trioxide‐induced systemic and mitochondrial dysfunction and DNA damage . Environmental Toxicology 24:4, pages 377-387.
Crossref
Apostolia Maria Tsimberidou, Luis H. Camacho, Srdan Verstovsek, Chaan Ng, David S. Hong, Cynthia K. Uehara, Catalina Gutierrez, Shawn Daring, Jan Stevens, Philip B. Komarnitsky, Brian Schwartz & Razelle Kurzrock. (2009) A Phase I Clinical Trial of Darinaparsin in Patients with Refractory Solid Tumors. Clinical Cancer Research 15:14, pages 4769-4776.
Crossref
Aparajita Ghosh, Ardhendu K. Mandal, Sibani Sarkar, Subhamay Panda & Nirmalendu Das. (2009) Nanoencapsulation of quercetin enhances its dietary efficacy in combating arsenic-induced oxidative damage in liver and brain of rats. Life Sciences 84:3-4, pages 75-80.
Crossref
George Braitberg. 2009. Critical Care Nephrology. Critical Care Nephrology 905 918 .
Nilanjana Banerjee, Mayukh Banerjee, Sudipto Ganguly, Santu Bandyopadhyay, Jayanta K. Das, Apurba Bandyopadhay, Mitali Chatterjee & Ashok K. Giri. (2008) Arsenic-induced mitochondrial instability leading to programmed cell death in the exposed individuals. Toxicology 246:2-3, pages 101-111.
Crossref
Pritha Ghosh, Mayukh Banerjee, Sujata De Chaudhuri, Rajdeep Chowdhury, Jayanta K Das, Angshuman Mukherjee, Ajoy K Sarkar, Lakshmikanta Mondal, Kalipada Baidya, Tanmoy Jyoti Sau, Apurba Banerjee, Arindam Basu, Keya Chaudhuri, Kunal Ray & Ashok K Giri. (2006) Comparison of health effects between individuals with and without skin lesions in the population exposed to arsenic through drinking water in West Bengal, India. Journal of Exposure Science & Environmental Epidemiology 17:3, pages 215-223.
Crossref
DAVID C. PIGOTT & ERICA L. LIEBELT. 2007. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose 1147 1156 .
Anamika Basu, Arundhati Som, Sarbani Ghoshal, Lakshmikanta Mondal, Ramesh C. Chaubey, Hari N. Bhilwade, Mohammad M. Rahman & Ashok K. Giri. (2005) Assessment of DNA damage in peripheral blood lymphocytes of individuals susceptible to arsenic induced toxicity in West Bengal, India. Toxicology Letters 159:1, pages 100-112.
Crossref
Swaran J.S. Flora, Smrati Bhadauria, Satish C. Pant & Ram K. Dhaked. (2005) Arsenic induced blood and brain oxidative stress and its response to some thiol chelators in rats. Life Sciences 77:18, pages 2324-2337.
Crossref
Jaspreet Singh Jaggi, Barry J. Kappel, Michael R. McDevitt, George Sgouros, Carlos D. Flombaum, Catalina Cabassa & David A. Scheinberg. (2005) Efforts to Control the Errant Products of a Targeted In vivo Generator . Cancer Research 65:11, pages 4888-4895.
Crossref
Anamika Basu, Pritha Ghosh, Jayanta K. Das, Apurba Banerjee, Kunal Ray & Ashok K. Giri. (2004) Micronuclei as Biomarkers of Carcinogen Exposure in Populations Exposed to Arsenic Through Drinking Water in West Bengal, India: A Comparative Study in Three Cell Types. Cancer Epidemiology, Biomarkers & Prevention 13:5, pages 820-827.
Crossref
Gurusamy M. Kannan & Swaran J.S. Flora. (2004) Chronic arsenic poisoning in the rat: treatment with combined administration of succimers and an antioxidant. Ecotoxicology and Environmental Safety 58:1, pages 37-43.
Crossref
J. Mahata, A. Basu, S. Ghoshal, J.N. Sarkar, A.K. Roy, G. Poddar, A.K. Nandy, A. Banerjee, K. Ray, A.T. Natarajan, R. Nilsson & A.K. Giri. (2003) Chromosomal aberrations and sister chromatid exchanges in individuals exposed to arsenic through drinking water in West Bengal, India. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 534:1-2, pages 133-143.
Crossref
D.N. Guha Mazumder. 2003. Arsenic Exposure and Health Effects V. Arsenic Exposure and Health Effects V 117 133 .
Dipankar Chakraborti, Mrinal Kumar Sengupta, Mohammad Mahmudur Rahman, Uttam Kumar Chowdhury, Dilip Lodh, Sad Ahamed, Md. Amir Hossain, Gautam Kumar Basu, Subhash Chandra Mukherjee & Kshitish Chandra Saha. 2003. Arsenic Exposure and Health Effects V. Arsenic Exposure and Health Effects V 3 24 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.