1,319
Views
235
CrossRef citations to date
0
Altmetric
Research Article

Acetaminophen Hepatotoxicity: The First 35 Years

Pages 3-20 | Published online: 29 Apr 2002

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (39)

Angela L. Chiew & Geoffrey K. Isbister. (2023) Advances in the understanding of acetaminophen toxicity mechanisms: a clinical toxicology perspective. Expert Opinion on Drug Metabolism & Toxicology 0:0, pages 1-16.
Read now
Chun En Yau, Haoyang Chen, Bryant Po-Yuen Lim, Mingwei Ng, R. Ponampalam, Daniel Yan Zheng Lim, Yip Han Chin & Andrew Fu Wah Ho. (2023) Performance of the paracetamol-aminotransferase multiplication product in risk stratification after paracetamol (acetaminophen) poisoning: a systematic review and meta-analysis. Clinical Toxicology 61:1, pages 1-11.
Read now
Naura Syafira, Andis Graudins, Mark Yarema & Anselm Wong. (2022) Comparing development of liver injury using the two versus three bag acetylcysteine regimen despite early treatment in paracetamol overdose. Clinical Toxicology 60:4, pages 478-485.
Read now
Stephanie L. Link, Garrett Rampon, Stephen Osmon, Anthony J. Scalzo & Barry H. Rumack. (2022) Fomepizole as an adjunct in acetylcysteine treated acetaminophen overdose patients: a case series. Clinical Toxicology 60:4, pages 472-477.
Read now
Faisal Syed Minhaj, James B. Leonard, Hyunuk Seung, Bruce D. Anderson, Wendy Klein-Schwartz & Joshua D. King. (2022) In vitro analysis of n-acetylcysteine (NAC) interference with the international normalized ratio (INR). Clinical Toxicology 60:4, pages 489-492.
Read now
Kevin Burnham, Tianrui Yang, Haleigh Smith & Steven Knight. (2021) A review of alternative intravenous acetylcysteine regimens for acetaminophen overdose. Expert Review of Clinical Pharmacology 14:10, pages 1267-1278.
Read now
John W. Downs, Kirk L. Cumpston, Emily K. Kershner, Michelle M. Troendle, S. Rutherfoord Rose & Brandon K. Wills. (2021) Clinical outcome of massive acetaminophen overdose treated with standard-dose N-acetylcysteine. Clinical Toxicology 59:10, pages 932-936.
Read now
Mitchell R. McGill & Jack A. Hinson. (2020) The development and hepatotoxicity of acetaminophen: reviewing over a century of progress. Drug Metabolism Reviews 52:4, pages 472-500.
Read now
Yu Kwan Li, Ka Fung Lam, Cheung Lun William Wong & Anselm Wong. (2020) In vitro study of pharmacobezoar formation in simulated acetaminophen overdose. Clinical Toxicology 58:9, pages 900-906.
Read now
Elie Harmouche, Misha Bhandari, Mary Ann Howland & Mark K Su. (2020) In response to: "Changing nomogram risk zone classification with serial testing after acute acetaminophen overdose: a retrospective database analysis". Clinical Toxicology 58:3, pages 220-221.
Read now
Adam Mutsaers, Jason P. Green, Marco L. A. Sivilotti, Mark C. Yarema, Dylan Tucker, David W. Johnson, Daniel A. Spyker & Barry H. Rumack. (2019) Changing nomogram risk zone classification with serial testing after acute acetaminophen overdose: a retrospective database analysis. Clinical Toxicology 57:6, pages 380-386.
Read now
Mikko J. Parry, Helena Isoniemi, Anna-Maria Koivusalo & Kalle Hoppu. (2018) Increased acetaminophen related calls to Finnish PIC better reflect acetaminophen sales than serious poisonings. Clinical Toxicology 56:3, pages 209-215.
Read now
Angela L. Chiew, Geoffrey K. Isbister, Katharine A. Kirby, Colin B. Page, Betty S. H. Chan & Nicholas A. Buckley. (2017) Massive paracetamol overdose: an observational study of the effect of activated charcoal and increased acetylcysteine dose (ATOM-2). Clinical Toxicology 55:10, pages 1055-1065.
Read now
Anselm Wong & Andis Graudins. (2017) Risk prediction of hepatotoxicity in paracetamol poisoning. Clinical Toxicology 55:8, pages 879-892.
Read now
Michael Levine, Sam Stellpflug, Anthony F. Pizon, Stephen Traub, Rais Vohra, Timothy Wiegand, Nicole Traub, David Tashman, Shoma Desai, Jamie Chang, Dhruv Nathwani & Stephen Thomas. (2017) Estimating the impact of adopting the revised United Kingdom acetaminophen treatment nomogram in the U.S. population. Clinical Toxicology 55:6, pages 569-572.
Read now
Marc Ghannoum, Sara Kazim, Ami M. Grunbaum, Eric Villeneuve & Sophie Gosselin. (2016) Massive acetaminophen overdose: effect of hemodialysis on acetaminophen and acetylcysteine kinetics. Clinical Toxicology 54:6, pages 519-522.
Read now
David G. Cairney, Hannah K. S. Beckwith, Khalid Al-Hourani, Michael Eddleston, D. Nicholas Bateman & James W. Dear. (2016) Plasma paracetamol concentration at hospital presentation has a dose-dependent relationship with liver injury despite prompt treatment with intravenous acetylcysteine. Clinical Toxicology 54:5, pages 405-410.
Read now
Jonathan G. Stine & James H. Lewis. (2016) Current and future directions in the treatment and prevention of drug-induced liver injury: a systematic review. Expert Review of Gastroenterology & Hepatology 10:4, pages 517-536.
Read now
Ronald I. Kirschner, Christina M. Rozier, Lynette M. Smith & Kathy L. Jacobitz. (2016) Nomogram line crossing after acetaminophen combination product overdose. Clinical Toxicology 54:1, pages 40-46.
Read now
Steven A. Seifert, Ronald I. Kirschner, Thomas G. Martin, Ronald M. Schrader, Kimberly Karowski & Peter C. Anaradian. (2015) Acetaminophen concentrations prior to 4 hours of ingestion: Impact on diagnostic decision-making and treatment. Clinical Toxicology 53:7, pages 618-623.
Read now
S. Gosselin, D. N. Juurlink, J. T. Kielstein, M. Ghannoum, V. Lavergne, T. D. Nolin & R. S. Hoffman. (2014) Extracorporeal treatment for acetaminophen poisoning: Recommendations from the EXTRIP workgroup. Clinical Toxicology 52:8, pages 856-867.
Read now
M. J. Hodgman. (2014) Seeking a role, Psi and APAP×AT as acetaminophen risk assessment tools. Clinical Toxicology 52:5, pages 451-453.
Read now
M. L. A. Sivilotti, D. N. Juurlink, J. S. Garland, I. Lenga, R. Poley, L. N. Hanly & M. Thompson. (2013) Antidote removal during haemodialysis for massive acetaminophen overdose. Clinical Toxicology 51:9, pages 855-863.
Read now
Lars E. Schmidt. (2013) Response to Letter: Anaphylactoid reactions to NAC. Clinical Toxicology 51:8, pages 813-813.
Read now
Laura P James, Prit Gill & Pippa Simpson. (2013) Predicting risk in patients with acetaminophen overdose. Expert Review of Gastroenterology & Hepatology 7:6, pages 509-512.
Read now
S. Gosselin, R. S. Hoffman, D. N. Juurlink, I. Whyte, M. Yarema & J. Caro. (2013) Treating acetaminophen overdose: thresholds, costs and uncertainties. Clinical Toxicology 51:3, pages 130-133.
Read now
W Stephen Waring. (2012) Criteria for acetylcysteine treatment and clinical outcomes after paracetamol poisoning. Expert Review of Clinical Pharmacology 5:3, pages 311-318.
Read now
Barry H Rumack & D Nicholas Bateman. (2012) Acetaminophen and acetylcysteine dose and duration: Past, present and future. Clinical Toxicology 50:2, pages 91-98.
Read now
Summon Chomchai, Chulithida Chomchai & Taweepong Anusornsuwan. (2011) Acetaminophen psi parameter: A useful tool to quantify hepatotoxicity risk in acute acetaminophen overdose. Clinical Toxicology 49:7, pages 664-667.
Read now
D. Nicholas Bateman & James Dear. (2010) Medicine, poison, and mystic potion: a personal perspective on paracetamol Louis Roche lecture, Stockholm, 2009. Clinical Toxicology 48:2, pages 97-103.
Read now
Richard C. Dart, Andrew R. Erdman, Kent R. Olson, Gwenn Christianson, Anthony S. Manoguerra, Peter A. Chyka, E. Martin Caravati, Paul M. Wax, Daniel C. Keyes, Alan D. Woolf, Elizabeth J. Scharman, Lisa L. Booze & William G. Troutman. (2006) Acetaminophen Poisoning: an Evidence-Based Consensus Guideline for Out-of-Hospital Management. Clinical Toxicology 44:1, pages 1-18.
Read now
Marco L. A Sivilotti, Angela M. Good, Mark C. Yarema, David N. Juurlink & David W. Johnson. (2005) A New Predictor of Toxicity Following Acetaminophen Overdose Based on Pretreatment Exposure. Clinical Toxicology 43:4, pages 229-234.
Read now
P. David Josephy. (2005) The Molecular Toxicology of Acetaminophen. Drug Metabolism Reviews 37:4, pages 581-594.
Read now
G. Randall Bond. (2004) Reduced Toxicity of Acetaminophen in Children: It's the Liver. Journal of Toxicology: Clinical Toxicology 42:2, pages 149-152.
Read now

Articles from other publishers (196)

Melissa A. Mercer, Jennifer L. Davis, Harold C. McKenzie, Christopher R. Byron, Maureen E. Kelleher, Lauren Trager, Thomas E. Cecere, Katie E. Wilson, R. M. Council‐Troche & Stephen R. Werre. (2023) Pharmacokinetics, clinical efficacy and safety of acetaminophen (paracetamol) in adult horses with naturally occurring chronic lameness. Equine Veterinary Journal 56:1, pages 202-214.
Crossref
David E. Kleiner. 2024. MacSween's Pathology of the Liver. MacSween's Pathology of the Liver 726 841 .
Gary C. Kanel. 2024. Atlas of Liver Pathology. Atlas of Liver Pathology 133 183.e10 .
Doaa M El-Gharbawy, Ibrahim Ali Kabbash & Mona M Ghonem. (2023) A nomogram proposal for early prediction of intensive care unit admission in patients with acute antipsychotic poisoning. Toxicology Research 12:5, pages 873-883.
Crossref
Kannan Sridharan, Mwila Mulubwa & Ali Mohamed Qader. (2023) Population Pharmacokinetic Modeling and Dose Optimization of Acetaminophen and its Metabolites Following Intravenous Infusion in Critically ill Adults. European Journal of Drug Metabolism and Pharmacokinetics 48:5, pages 531-540.
Crossref
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee & Victor Navarro. (2023) AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury. Hepatology 77:3, pages 1036-1065.
Crossref
Nicola Di-Iacovo, Stefania Pieroni, Danilo Piobbico, Marilena Castelli, Damiano Scopetti, Simona Ferracchiato, Maria Agnese Della-Fazia & Giuseppe Servillo. (2023) Liver Regeneration and Immunity: A Tale to Tell. International Journal of Molecular Sciences 24:2, pages 1176.
Crossref
Jan-Luca Stampf, Cosmin I. Ciotu, Stefan Heber, Stefan Boehm, Michael J. M. Fischer & Isabella Salzer. (2022) Analgesic Action of Acetaminophen via Kv7 Channels. International Journal of Molecular Sciences 24:1, pages 650.
Crossref
Rahul Gupta, Amir Hossein Behnoush, David Egeler & Wilbert S Aronow. (2022) Effect of acetaminophen on blood pressure: a systematic review and meta-analysis of randomized controlled trials. European Journal of Preventive Cardiology 29:14, pages e326-e330.
Crossref
Nida Mirza. 2022. Hepatotoxicity. Hepatotoxicity.
Mohammad Hossain Shariare, Nusrat Jahan Khan Pinky, Joynal Abedin, Mohsin Kazi, Mohammed S. Aldughaim & Mohammad N. Uddin. (2022) Liposomal Drug Delivery of Blumea lacera Leaf Extract: In-Vivo Hepatoprotective Effects. Nanomaterials 12:13, pages 2262.
Crossref
Ashley N Webb & Joshua Hayden. (2022) Not All Acetaminophen Assays Are Fit for Purpose. The Journal of Applied Laboratory Medicine 7:3, pages 812-814.
Crossref
Uzung Yoon, James Topper & Jordan Goldhammer. (2022) Preoperative Evaluation and Anesthetic Management of Patients With Liver Cirrhosis Undergoing Cardiac Surgery. Journal of Cardiothoracic and Vascular Anesthesia 36:5, pages 1429-1448.
Crossref
Nahar AlRuwaili, Faten Zaidan, Areej AlFattani & Saud Alenazi. (2022) Urgent need to standardize labelling of acetaminophen-paediatric liquid drug products in Saudi Arabia. International Journal of Pediatrics and Adolescent Medicine 9:1, pages 62-65.
Crossref
Ali Mohammad Pourbagher-Shahri, Jonathan Schimmel, Farshad M. Shirazi, Samaneh Nakhaee & Omid Mehrpour. (2022) Use of fomepizole (4-methylpyrazole) for acetaminophen poisoning: A scoping review. Toxicology Letters 355, pages 47-61.
Crossref
Jephte Y. Akakpo, Anup Ramachandran, Steven C. Curry, Barry H. Rumack & Hartmut Jaeschke. (2022) Comparing N-acetylcysteine and 4-methylpyrazole as antidotes for acetaminophen overdose. Archives of Toxicology 96:2, pages 453-465.
Crossref
Summon Chomchai, Pattaraporn Mekavuthikul, Jariya Phuditshinnapatra & Chulathida Chomchai. (2022) Sensitivity of dose‐estimations for acute acetaminophen overdose in predicting hepatotoxicity risk using the Rumack‐Matthew Nomogram. Pharmacology Research & Perspectives 10:1.
Crossref
John Rague. 2022. History of Modern Clinical Toxicology. History of Modern Clinical Toxicology 201 212 .
L. T. van der Heijden, P. Mian, J. Hias, B. C. M. de Winter, J. Tournoy, L. Van der Linden, D. Tibboel, K. Walgraeve, J. Flamaing, B. C. P. Koch, K. Allegaert & I. Spriet. (2021) Highly Variable Paracetamol Pharmacokinetics After Multiple Oral Dosing in Frail Older People: A Population Pharmacokinetic Analysis. Drugs & Aging 39:1, pages 83-95.
Crossref
Daan Zillen, Kris L. L. Movig, Gert Kant, Joost B. Masselink & Paola Mian. (2021) Impact of malnourishment on the pharmacokinetics of acetaminophen and susceptibility to acetaminophen hepatotoxicity. Clinical Case Reports 9:11.
Crossref
Sofie A. M. Brookhuis, Karel Allegaert, Lidwien M. Hanff, Marjolijn N. Lub-de Hooge, André Dallmann & Paola Mian. (2021) Modelling Tools to Characterize Acetaminophen Pharmacokinetics in the Pregnant Population. Pharmaceutics 13:8, pages 1302.
Crossref
Iwona Popiolek, Piotr Hydzik, Pawel Jagielski, Monika Zrodlowska, Karol Mystek & Grzegorz Porebski. (2021) Risk Factors for Hepatotoxicity Due to Paracetamol Overdose in Adults. Medicina 57:8, pages 752.
Crossref
Marie-France Forget & Han Ting Wang. 2021. Opioid Use in Critical Care. Opioid Use in Critical Care 247 264 .
Alireza Amirabadizadeh, Samaneh Nakhaee, Firoozeh Jahani, Sima Soorgi, Christopher O. Hoyte & Omid Mehrpour. (2020) Prognostic indicators in critically ill poisoned patients: development of a risk-prediction nomogram. Drug Metabolism and Drug Interactions 35:4.
Crossref
Gary Eichenbaum, Kyunghee Yang, Yeshitila Gebremichael, Brett A. Howell, F. Jay Murray, David Jacobson-Kram, Hartmut Jaeschke, Edwin Kuffner, Cathy K. Gelotte, John C.K. Lai, Daniele Wikoff & Evren Atillasoy. (2020) Application of the DILIsym® Quantitative Systems Toxicology drug-induced liver injury model to evaluate the carcinogenic hazard potential of acetaminophen. Regulatory Toxicology and Pharmacology 118, pages 104788.
Crossref
Niklas Wester, Bjørn F. Mikladal, Ilkka Varjos, Antti Peltonen, Eija Kalso, Tuomas Lilius, Tomi Laurila & Jari Koskinen. (2020) Disposable Nafion-Coated Single-Walled Carbon Nanotube Test Strip for Electrochemical Quantitative Determination of Acetaminophen in a Finger-Prick Whole Blood Sample. Analytical Chemistry 92:19, pages 13017-13024.
Crossref
Alireza Amirabadizadeh, Samaneh Nakhaee, Firoozeh Jahani, Sima Soorgi, Christopher O. Hoyte & Omid Mehrpour. (2020) Prognostic indicators in critically ill poisoned patients: development of a risk-prediction nomogram. Drug Metabolism and Personalized Therapy 0:0.
Crossref
Melissa M. Clemens, Joel H. Vazquez, Stefanie Kennon-McGill, Sandra S. McCullough, Laura P. James & Mitchell R. McGill. (2020) Pre-treatment twice with liposomal clodronate protects against acetaminophen hepatotoxicity through a pre-conditioning effect. Liver Research 4:3, pages 145-152.
Crossref
Khrystyna Zakalska & O Babiichuk. (2020) Paracetamol as a basic component of a modern approach to adequate perioperative analgesia. Pain medicine 5:1, pages 15-22.
Crossref
Laura Rotundo & Nikolaos Pyrsopoulos. (2020) Liver injury induced by paracetamol and challenges associated with intentional and unintentional use. World Journal of Hepatology 12:4, pages 125-136.
Crossref
Anselm Wong, Kennon Heard, Andis Graudins, Richard Dart & Marco L. A. Sivilotti. (2020) Adducts Post Acetaminophen Overdose Treated with a 12-Hour vs 20-Hour Acetylcysteine Infusion. Journal of Medical Toxicology 16:2, pages 188-194.
Crossref
Angela L Chiew, David Reith, Adam Pomerleau, Anselm Wong, Katherine Z Isoardi, Jessamine Soderstrom & Nicholas A Buckley. (2019) Updated guidelines for the management of paracetamol poisoning in Australia and New Zealand. Medical Journal of Australia 212:4, pages 175-183.
Crossref
Laura P. James, Mitchell R. McGill, Dean W. Roberts, Jack A. Hinson & William M. Lee. 2020. 35 50 .
D. Adam Algren. 2020. Toxicology Cases for the Clinical and Forensic Laboratory. Toxicology Cases for the Clinical and Forensic Laboratory 75 77 .
Paola Mian, John N. van den Anker, Kristel van Calsteren, Pieter Annaert, Dick Tibboel, Marc Pfister, Karel Allegaert & André Dallmann. (2019) Physiologically Based Pharmacokinetic Modeling to Characterize Acetaminophen Pharmacokinetics and N-Acetyl-p-Benzoquinone Imine (NAPQI) Formation in Non-Pregnant and Pregnant Women. Clinical Pharmacokinetics 59:1, pages 97-110.
Crossref
R Todd Stravitz & William M Lee. (2019) Acute liver failure. The Lancet 394:10201, pages 869-881.
Crossref
P. Mian, A.J. Valkenburg, K. Allegaert, B.C.P. Koch, C.V. Breatnach, C.A.J. Knibbe, D. Tibboel & E.H.J. Krekels. (2019) Population Pharmacokinetic Modeling of Acetaminophen and Metabolites in Children After Cardiac Surgery With Cardiopulmonary Bypass. The Journal of Clinical Pharmacology 59:6, pages 847-855.
Crossref
Sharon C. Reale, Kathryn J. Gray, Edward W. BoyerDominique Y. Arce & Michaela K. Farber. (2019) Toxic Ingestion of Acetaminophen and Acetylsalicylic Acid in a Parturient at 33 Weeks Gestation: A Case Report. A&A Practice 12:9, pages 302-304.
Crossref
Anselm Wong, Richard McNulty, David Taylor, Marco Sivilotti, Shaun Greene, Naren Gunja, Zeff Koutsogiannis & Andis Graudins. (2019) The NACSTOP Trial: A Multicenter, Cluster‐Controlled Trial of Early Cessation of Acetylcysteine in Acetaminophen Overdose. Hepatology 69:2, pages 774-784.
Crossref
P. Mian, M. J. Esdonk, K. T. Olkkola, B. C. M. Winter, A. Liukas, I. Spriet, D. Tibboel, M. Petrovic, B. C. P. Koch & K. Allegaert. (2018) Population pharmacokinetic modelling of intravenous paracetamol in fit older people displays extensive unexplained variability. British Journal of Clinical Pharmacology 85:1, pages 126-135.
Crossref
Erik S. Fisher & Steven C. Curry. 2019. Drug-induced Liver Injury. Drug-induced Liver Injury 263 272 .
Angela L. Chiew & Geoffrey K. Isbister. 2019. The Therapeutic Use of N-Acetylcysteine (NAC) in Medicine. The Therapeutic Use of N-Acetylcysteine (NAC) in Medicine 147 168 .
Pietro Ghezzi, Kevin V. Lemley, James P. Andrus, Stephen C. De Rosa, Arne Holmgren, Dean Jones, Farook Jahoor, Richard Kopke, Ian Cotgreave, Teodoro Bottiglieri, Neil Kaplowitz, Hajime Nakamura, Frank Staal, Stephen W. Ela, Kondala R. Atkuri, Rabindra Tirouvanziam, Kartoosh Heydari, Bita Sahaf, Andrew Zolopa, Richard Eugene Frye, John J. Mantovani, Leonard A. Herzenberg & Leonore A. Herzenberg. 2019. The Therapeutic Use of N-Acetylcysteine (NAC) in Medicine. The Therapeutic Use of N-Acetylcysteine (NAC) in Medicine 349 386 .
Dilin Tang, Wui Ling Chan & Dong Haur Phua. (2018) Performance of an emergency department observation unit protocol in reducing length of stay for acetaminophen overdose: a retrospective study. International Journal of Emergency Medicine 11:1.
Crossref
Suzanne L. Parker, Manoj Saxena, John Gowardman, Jeffrey Lipman, John Myburgh & Jason A. Roberts. (2018) Population pharmacokinetics of intravenous paracetamol in critically ill patients with traumatic brain injury. Journal of Critical Care 47, pages 15-20.
Crossref
Diego Castanares-Zapatero, Valérie Dinant, Ilaria Ruggiano, Harold Willem, Pierre-François Laterre & Philippe Hantson. (2018) Pattern of Paracetamol Poisoning: Influence on Outcome and Complications. Toxics 6:4, pages 58.
Crossref
Paola Mian, Karel Allegaert, Isabel Spriet, Dick Tibboel & Mirko Petrovic. (2018) Paracetamol in Older People: Towards Evidence-Based Dosing?. Drugs & Aging 35:7, pages 603-624.
Crossref
Brittany D. Bissell, Jason E. Davis, Alexander H. Flannery, David A. Adkins & Melissa L. Thompson Bastin. (2017) Aggressive Treatment of Life-Threatening Hypophosphatemia During Recovery From Fulminant Hepatic Failure: A Case Report. Journal of Intensive Care Medicine 33:6, pages 375-379.
Crossref
Taehyun Roh, Umasankar De, Seong Kwang Lim, Min Kook Kim, Seul Min Choi, Duck Soo Lim, Sungpil Yoon, Sam Kacew, Hyung Sik Kim & Byung-Mu Lee. (2018) Detoxifying effect of pyridoxine on acetaminophen-induced hepatotoxicity via suppressing oxidative stress injury. Food and Chemical Toxicology 114, pages 11-22.
Crossref
Thomas M. Caparrotta, Daniel J. Antoine & James W. Dear. (2017) Are some people at increased risk of paracetamol-induced liver injury? A critical review of the literature. European Journal of Clinical Pharmacology 74:2, pages 147-160.
Crossref
Débora F. Gonçalves, Nelson R. de Carvalho, Martim B. Leite, Aline A. Courtes, Diane D. Hartmann, Sílvio T. Stefanello, Ingrid K. da Silva, Jéferson L. Franco, Félix A.A. Soares & Cristiane L. Dalla Corte. (2018) Caffeine and acetaminophen association: Effects on mitochondrial bioenergetics. Life Sciences 193, pages 234-241.
Crossref
David E. Kleiner. 2018. Macsween's Pathology of the Liver. Macsween's Pathology of the Liver 673 779 .
James H. Lewis. 2018. Handbook of Liver Disease. Handbook of Liver Disease 130 157 .
David E. Kleiner. 2018. Practical Hepatic Pathology: a Diagnostic Approach. Practical Hepatic Pathology: a Diagnostic Approach 327 370 .
Summon Chomchai & Chulathida Chomchai. (2018) Being overweight or obese as a risk factor for acute liver injury secondary to acute acetaminophen overdose. Pharmacoepidemiology and Drug Safety 27:1, pages 19-24.
Crossref
Robert B Flint, Daniella W Roofthooft, Anne van Rongen, Richard A van Lingen, Johannes N van den Anker, Monique van Dijk, Karel Allegaert, Dick Tibboel, Catherijne A J Knibbe & Sinno H P Simons. (2017) Exposure to acetaminophen and all its metabolites upon 10, 15, and 20 mg/kg intravenous acetaminophen in very-preterm infants. Pediatric Research 82:4, pages 678-684.
Crossref
Anselm Wong, Cornelia Landersdorfer & Andis Graudins. (2017) Pharmacokinetic modelling of modified acetylcysteine infusion regimens used in the treatment of paracetamol poisoning. European Journal of Clinical Pharmacology 73:9, pages 1103-1110.
Crossref
Tomáš Hložek, Tomáš Křížek, Petr Tůma, Miroslava Bursová, Pavel Coufal & Radomír Čabala. (2017) Quantification of paracetamol and 5-oxoproline in serum by capillary electrophoresis: Implication for clinical toxicology. Journal of Pharmaceutical and Biomedical Analysis.
Crossref
A. Hern?ndez-Tejedor, O. Pe?uelas, G. Sirgo Rodr?guez, J.A. Llompart-Pou, E. Palencia Herrej?n, A. Estella, M.P. Fuset Cabanes, M.A. Alcal?-Llorente, P. Ram?rez Galleymore, B. Ob?n Azuara, J.A. Lorente Balanza, C. Vaquerizo Alonso, M.A. Ballesteros Sanz, M. Garc?a Garc?a, J. Caballero L?pez, A. Socias Mir, A. Serrano L?zaro, J.M. P?rez Villares & M.E. Herrera-Guti?rrez. (2017) Recommendations of the Working Groups from the Spanish Society of Intensive and Critical Care Medicine and Coronary Units (SEMICYUC) for the management of adult critically ill patients. Medicina Intensiva (English Edition) 41:5, pages 285-305.
Crossref
A. Hern?ndez-Tejedor, O. Pe?uelas, G. Sirgo Rodr?guez, J.A. Llompart-Pou, E. Palencia Herrej?n, A. Estella, M.P. Fuset Cabanes, M.A. Alcal?-Llorente, P. Ram?rez Galleymore, B. Ob?n Azuara, J.A. Lorente Balanza, C. Vaquerizo Alonso, M.A. Ballesteros Sanz, M. Garc?a Garc?a, J. Caballero L?pez, A. Socias Mir, A. Serrano L?zaro, J.M. P?rez Villares & M.E. Herrera-Guti?rrez. (2017) Recomendaciones para el tratamiento de los pacientes cr?ticos de los Grupos de Trabajo de la Sociedad Espa?ola de Medicina Intensiva, Cr?tica y Unidades Coronarias (SEMICYUC). Medicina Intensiva 41:5, pages 285-305.
Crossref
Robert B. Flint, Paola MianBart van der NagelNuria SlijkhuisBirgit C. P. Koch. (2017) Quantification of Acetaminophen and Its Metabolites in Plasma Using UPLC-MS: Doors Open to Therapeutic Drug Monitoring in Special Patient Populations. Therapeutic Drug Monitoring 39:2, pages 164-171.
Crossref
. 2017. Observation Medicine. Observation Medicine 323 330 .
Catalina Lionte, Victorita Sorodoc, Elisabeta Jaba & Alina Botezat. (2017) Development and validation of a risk-prediction nomogram for in-hospital mortality in adults poisoned with drugs and nonpharmaceutical agents. Medicine 96:12, pages e6404.
Crossref
Todd J. Zurlinden & Brad Reisfeld. (2016) Characterizing the Effects of Race/Ethnicity on Acetaminophen Pharmacokinetics Using Physiologically Based Pharmacokinetic Modeling. European Journal of Drug Metabolism and Pharmacokinetics 42:1, pages 143-153.
Crossref
Wesam Gamal, Philipp Treskes, Kay Samuel, Gareth J. Sullivan, Richard Siller, Vlastimil Srsen, Katie Morgan, Anna Bryans, Ada Kozlowska, Andreas Koulovasilopoulos, Ian Underwood, Stewart Smith, Jorge del-Pozo, Sharon Moss, Alexandra Inés Thompson, Neil C. Henderson, Peter C. Hayes, John N. Plevris, Pierre-Olivier Bagnaninchi & Leonard J. Nelson. (2017) Low-dose acetaminophen induces early disruption of cell-cell tight junctions in human hepatic cells and mouse liver. Scientific Reports 7:1.
Crossref
Philippe Hoffmann. (2017) Interpr?tation des r?sultats du bilan biologique en cas d?intoxication accidentelle au parac?tamol. Revue Francophone des Laboratoires 2017:488, pages 72-76.
Crossref
Paul L. Marino. 2017. Das ICU-Buch. Das ICU-Buch 813 826 .
D. Nicholas Bateman. 2017. Critical Care Toxicology. Critical Care Toxicology 1145 1169 .
Sa’ed H. Zyoud, W. Stephen Waring, Samah W. Al-Jabi, Waleed M. Sweileh & Rahmat Awang. (2016) The 100 most influential publications in paracetamol poisoning treatment: a bibliometric analysis of human studies. SpringerPlus 5:1.
Crossref
Thanaporn Wattanakul, Pramote Teerapong, Katherine Plewes, Paul N. Newton, Wirongrong Chierakul, Kamolrat Silamut, Kesinee Chotivanich, Ronnatrai Ruengweerayut, Nicholas J. White, Arjen M. Dondorp & Joel Tarning. (2016) Pharmacokinetic properties of intramuscular versus oral syrup paracetamol in Plasmodium falciparum malaria. Malaria Journal 15:1.
Crossref
M. VRBOVÁ, E. ROUŠAROVÁ, L. BRŮČKOVÁ, P. ČESLA & T. ROUŠAR. (2016) Characterization of Acetaminophen Toxicity in Human Kidney HK-2 Cells. Physiological Research, pages 627-635.
Crossref
Phillip S. Ge & Bruce A. Runyon. (2016) Treatment of Patients with Cirrhosis. New England Journal of Medicine 375:8, pages 767-777.
Crossref
Anne van Rongen, Pyry A. J. V?litalo, Mariska Y. M. Peeters, Djamila Boerma, Fokko W. Huisman, Bert van Ramshorst, Eric P. A. van Dongen, Johannes N. van den Anker & Catherijne A. J. Knibbe. (2016) Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen. Clinical Pharmacokinetics 55:7, pages 833-847.
Crossref
Todd J. Zurlinden & Brad Reisfeld. (2015) Physiologically based modeling of the pharmacokinetics of acetaminophen and its major metabolites in humans using a Bayesian population approach. European Journal of Drug Metabolism and Pharmacokinetics 41:3, pages 267-280.
Crossref
Todd J. Zurlinden, Kennon Heard & Brad Reisfeld. (2016) A novel approach for estimating ingested dose associated with paracetamol overdose. British Journal of Clinical Pharmacology 81:4, pages 634-645.
Crossref
Scott N. Lucyk, Mark C. Yarema, Marco L.A. Sivilotti, David W. Johnson, Alberto Nettel-Aguirre, Charlemaigne Victorino, Benoit Bailey, Richard C. Dart, Kennon Heard, Daniel A. Spyker & Barry H. Rumack. (2016) Outcomes of Patients With Premature Discontinuation of the 21-h Intravenous N-Acetylcysteine Protocol After Acute Acetaminophen Overdose. The Journal of Emergency Medicine 50:4, pages 629-637.
Crossref
Yasutoshi SAKAMOTO, Mami WAKISAKAMika MAEDA, Ildae SONG, Tomoe FUJITA, Tomomi SEKINE, Akira YAMAZAKIRieko TANAKA & Yuji KUMAGAI. (2016) <b>Comparative Pharmacokinetic Study of Acetaminophen in Japanese and Han Chinese Individuals</b>. Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics 47:1, pages 11-16.
Crossref
Mario Rueda & Pamela A. Lipsett. 2016. Principles of Adult Surgical Critical Care. Principles of Adult Surgical Critical Care 211 232 .
D. Nicholas Bateman. 2016. Critical Care Toxicology. Critical Care Toxicology 1 25 .
H. Haouache & F. Lapostolle. (2015) Antidoti. EMC - Urgenze 19:3, pages 1-14.
Crossref
Bal-Ram Adhikari, Maduraiveeran Govindhan & Aicheng Chen. (2015) Sensitive Detection of Acetaminophen with Graphene-Based Electrochemical Sensor. Electrochimica Acta 162, pages 198-204.
Crossref
Matthieu Gr?goire, C?dric Bretonniere, Guillaume Deslandes, Catherine Monteil-Ganiere, R?gis Bouqui?Eric Dailly, Christian Renaud, Claudine Azoulay, Alain Pineau, H?l?ne Grison-Hernando & Pascale Jolliet. (2015) L?acidose lactique pr?coce lors de l?intoxication massive au parac?tamol?: un trouble m?tabolique parfois m?connu. Toxicologie Analytique et Clinique 27:1, pages 3-7.
Crossref
IbrahimM Esmat & HananM Farag. (2015) Comparative study between paracetamol and two different doses of pregabalin on postoperative pain in laparoscopic cholecystectomy. Saudi Journal of Anaesthesia 9:4, pages 376.
Crossref
D. Nicholas Bateman. 2016. Critical Care Toxicology. Critical Care Toxicology 1 25 .
Ayhan Saritas, Hayati Kandis, Davut Baltaci, Umran Yildirim, Halil Kaya, Ali Karakus, Serdar Colakoglu, Ramazan Memisogullari & Ismail Hamdi Kara. (2012) N -Acetyl cysteine and erdosteine treatment in acetaminophen-induced liver damage . Toxicology and Industrial Health 30:7, pages 670-678.
Crossref
Katie H. Owens, Philip G. M. Murphy, Natalie J. Medlicott, Julia Kennedy, Mathew Zacharias, Neil Curran, Sree Sreebhavan, Mark Thompson-Fawcett & David M. Reith. (2014) Population pharmacokinetics of intravenous acetaminophen and its metabolites in major surgical patients. Journal of Pharmacokinetics and Pharmacodynamics 41:3, pages 211-221.
Crossref
Shawn M. Varney, Jennie A. Buchanan, Jamie Kokko & Kennon Heard. (2014) Acetylcysteine for Acetaminophen Overdose in Patients Who Weigh >100 Kg. American Journal of Therapeutics 21:3, pages 159-163.
Crossref
Anselm Wong, Andis Graudins, Fergus Kerr & Shaun L Greene. (2014) Paracetamol toxicity: What would be the implications of a change in Australian treatment guidelines?. Emergency Medicine Australasia 26:2, pages 183-187.
Crossref
A. Zeidan, J.X. Mazoit, M. Ali Abdullah, H. Maaliki, TH Ghattas & A. Saifan. (2014) Median effective dose (ED50) of paracetamol and morphine for postoperative pain: a study of interaction. British Journal of Anaesthesia 112:1, pages 118-123.
Crossref
. 2014. Clinical Review of Oral and Maxillofacial Surgery. Clinical Review of Oral and Maxillofacial Surgery 29 64 .
Ali Navid, David M Ng, Benjamin J Stewart, Sergio E Wong & Felice C Lightstone. (2013) Quantitative In Silico analysis of transient metabolism of acetaminophen and associated causes of hepatotoxicity in humans. In Silico Pharmacology 1:1.
Crossref
Chalermrat Bunchorntavakul & K. Rajender Reddy. (2013) Acetaminophen-related Hepatotoxicity. Clinics in Liver Disease 17:4, pages 587-607.
Crossref
Blake A. Froberg, Kerry J. King, Theomal D. Kurera, Andrew A. Monte, Jane M. Prosser, Steven J. Walsh, Robert H. Riffenburgh, Daniel E. Rusyniak & David A. Tanen. (2013) Negative Predictive Value of Acetaminophen Concentrations Within Four?Hours of Ingestion. Academic Emergency Medicine 20:10, pages 1072-1075.
Crossref
Sean H. Rhyee. (2013) Early Serum Acetaminophen Levels: How Soon Is Too Soon?. Academic Emergency Medicine 20:10, pages 1070-1071.
Crossref
Frédéric Baud, Philippe Hantson & Hafedh ThabetA. Larocque. 2013. Intoxications aiguës. Intoxications aiguës 179 195 .
David J. McQuade, Paul I. Dargan, Jeff Keep & David M. Wood. (2012) Paracetamol toxicity: what would be the implications of a change in UK treatment guidelines?. European Journal of Clinical Pharmacology 68:11, pages 1541-1547.
Crossref
Michael J. Hodgman & Alexander R. Garrard. (2012) A Review of Acetaminophen Poisoning. Critical Care Clinics 28:4, pages 499-516.
Crossref
Scott B GroudineHoward S Smith & Duane Ellsworth. (2012) Role of intravenous acetaminophen in postoperative pain management. Pain Management 2:5, pages 509-519.
Crossref
Barry Rumack, Kennon Heard, Jody Green, Donald Albert, Becki Bucher‐Bartelson, Michael Bodmer, Marco L. A. Sivilotti & Richard C. Dart. (2012) Effect of Therapeutic Doses of Acetaminophen (up to 4 g/day) on Serum Alanine Aminotransferase Levels in Subjects Consuming Ethanol: Systematic Review and Meta‐analysis of Randomized Controlled Trials. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 32:9, pages 784-791.
Crossref
Patrick P. Dougherty & Wendy Klein-Schwartz. (2012) Unexpected Late Rise in Plasma Acetaminophen Concentrations with Change in Risk Stratification in Acute Acetaminophen Overdoses. The Journal of Emergency Medicine 43:1, pages 58-63.
Crossref
Chris Pasero & Daphne Stannard. (2012) The Role of Intravenous Acetaminophen in Acute Pain Management: A Case-Illustrated Review. Pain Management Nursing 13:2, pages 107-124.
Crossref
Margreke J.E. Brill, Jeroen Diepstraten, Anne van Rongen, Simone van Kralingen, John N. van den Anker & Catherijne A.J. Knibbe. (2012) Impact of Obesity on Drug Metabolism and Elimination in Adults and Children. Clinical Pharmacokinetics 51:5, pages 277-304.
Crossref
Anke Van Summeren, Johan Renes, Joost H.M. van Delft, Jos C.S. Kleinjans & Edwin C.M. Mariman. (2012) Proteomics in the search for mechanisms and biomarkers of drug-induced hepatotoxicity. Toxicology in Vitro 26:3, pages 373-385.
Crossref
Sarah Jefferies, Manoj Saxena & Paul Young. (2012) Paracetamol in critical illness: a review. Critical Care and Resuscitation 14:1, pages 74-80.
Crossref
Sa'ed H. Zyoud, Rahmat Awang & Syed Azhar Syed Sulaiman. (2011) Reliability of the reported ingested dose of acetaminophen for predicting the risk of toxicity in acetaminophen overdose patients. Pharmacoepidemiology and Drug Safety 21:2, pages 207-213.
Crossref
Thomas E. Robey & Edward R. Melnick. (2012) Undifferentiated Altered Mental Status: A Late Presentation of Toxic Acetaminophen Ingestion. Case Reports in Emergency Medicine 2012, pages 1-3.
Crossref
James H. Lewis & David E. Kleiner. 2012. MacSween's Pathology of the Liver. MacSween's Pathology of the Liver 645 760 .
A. Wayne Jones. 2012. Handbook of Drug Interactions. Handbook of Drug Interactions 499 586 .
Anne M. Larson. 2011. Schiff's Diseases of the Liver. Schiff's Diseases of the Liver 445 473 .
Mònica Sabaté, Luisa Ibáñez, Eulàlia Pérez, Xavier Vidal, Maria Buti, Xavier Xiol, Antoni Mas, Carlos Guarner, Montserrat Forné, Ricard Solà, José Castellote, Joaquim Rigau & Joan-Ramon Laporte. (2011) Paracetamol in therapeutic dosages and acute liver injury: causality assessment in a prospective case series. BMC Gastroenterology 11:1.
Crossref
Hayati Kandiş, Melih Engin Erkan, Ümran Yildirim, Harun Güneş, Mesut Erbaş, Hayriye AK Yildirim, Suat Gezer & İsmail Hamdi Kara. (2010) Comparison of the effects of N -acetyl cysteine and erdosteine in rats with renal injury caused by paracetamol intoxication . Human & Experimental Toxicology 30:9, pages 1350-1358.
Crossref
R. Bouchentouf, S. El jastimi, A. Benjelloun & M. A. Aitbenasser. (2011) H?patotoxicit? des antituberculeux : ?pid?miologie, m?canisme et conduite ? tenirHepatotoxicity of antituberculosis therapy: epidemiology, mechanism, and patient management. Journal Africain d'H?pato-Gastroent?rologie 5:3, pages 168-173.
Crossref
Howard S. Smith. (2011) Perioperative Intravenous Acetaminophen and NSAIDs. Pain Medicine 12:6, pages 961-981.
Crossref
Shannan R. Tujios & William M. Lee. 2011. Sherlock's Diseases of the Liver and Biliary System. Sherlock's Diseases of the Liver and Biliary System 70 93 .
Steven R. Offerman. (2010) The Clinical Management of Acetaminophen Poisoning in a Community Hospital System: Factors Associated with Hospital Length of Stay. Journal of Medical Toxicology 7:1, pages 4-11.
Crossref
Bruce Allen Runyon. (2011) A Primer on Detecting Cirrhosis and Caring for These Patients without Causing Harm. International Journal of Hepatology 2011, pages 1-8.
Crossref
Yedidia Bentur, Yael Lurie, Ada Tamir, Daniel C Keyes & Fuad Basis. (2010) Reliability of history of acetaminophen ingestion in intentional drug overdose patients. Human & Experimental Toxicology 30:1, pages 44-50.
Crossref
Harold I Zeliger. 2011. Human Toxicology of Chemical Mixtures. Human Toxicology of Chemical Mixtures 417 425 .
Gary C. Kanel & Jacob Korula. 2011. Atlas of Liver Pathology. Atlas of Liver Pathology 93 133 .
Lindsay Murray, Frank Daly, Mark Little & Mike Cadogan. 2011. Toxicology Handbook. Toxicology Handbook 127 370 .
David E. Kleiner. 2011. Practical Hepatic Pathology: A Diagnostic Approach. Practical Hepatic Pathology: A Diagnostic Approach 311 352 .
Ashley N. Webb & Prashant Joshi. 2011. Pediatric Critical Care. Pediatric Critical Care 1451 1462 .
Keith A. Candiotti, Sergio D. Bergese, Eugene R. Viscusi, Sonia K. Singla, Mike A. Royal & Neil Kumar Singla. (2010) Safety of Multiple-Dose Intravenous Acetaminophen in Adult Inpatients. Pain Medicine 11:12, pages 1841-1848.
Crossref
Robert G. Hendrickson, Nathanael J. McKeown, Patrick L. West & Christopher R. Burke. (2010) Bactrian (“Double Hump”) Acetaminophen Pharmacokinetics: A Case Series and Review of the Literature. Journal of Medical Toxicology 6:3, pages 337-344.
Crossref
Gary E. Hill, Babatunde Ogunnaike & Dawood Nasir. (2010) Patients Presenting with Acute Toxin Ingestion. Anesthesiology Clinics 28:1, pages 117-137.
Crossref
Tarjei Rygnestad. (2010) Legemiddelbehandling av akutte korsryggssmerter. Tidsskrift for Den norske legeforening 130:22, pages 2242-2243.
Crossref
Robert G. Hendrickson & Nathanael J. McKeown. 2010. Rosen's Emergency Medicine – Concepts and Clinical Practice. Rosen's Emergency Medicine – Concepts and Clinical Practice 1948 1953 .
Silas W. Smith. 2010. Molecular, Clinical and Environmental Toxicology. Molecular, Clinical and Environmental Toxicology 397 460 .
Rick D. Fannin, Mark Russo, Thomas M. O'Connell, Kevin Gerrish, Jason H. Winnike, Jeffrey Macdonald, Jack Newton, Shahid Malik, Stella O. Sieber, Joel Parker, Ruchir Shah, Tong Zhou, Paul B. Watkins & Richard S. Paules. (2010) Acetaminophen dosing of humans results in blood transcriptome and metabolome changes consistent with impaired oxidative phosphorylation. Hepatology 51:1, pages 227-236.
Crossref
David P. Betten, Elizabeth E. Burner, Stephen C. Thomas, Christian Tomaszewski & Richard F. Clark. (2009) A retrospective evaluation of shortened-duration oral N-acetylcysteine for the treatment of acetaminophen poisoning. Journal of Medical Toxicology 5:4, pages 183-190.
Crossref
Mark C. Yarema, David W. Johnson, Randall J. Berlin, Marco L.A. Sivilotti, Alberto Nettel-Aguirre, Rollin F. Brant, Daniel A. Spyker, Benoit Bailey, Dominic Chalut, Jacques S. Lee, Amy C. Plint, Roy A. Purssell, Tim Rutledge, Catherine A. Seviour, Ian G. Stiell, Margaret Thompson, Jeffrey Tyberg, Richard C. Dart & Barry H. Rumack. (2009) Comparison of the 20-Hour Intravenous and 72-Hour Oral Acetylcysteine Protocols for the Treatment of Acute Acetaminophen Poisoning. Annals of Emergency Medicine 54:4, pages 606-614.
Crossref
Laura P. James, Lynda Letzig, Pippa M. Simpson, Edmund Capparelli, Dean W. Roberts, Jack A. Hinson, Timothy J. Davern & William M. Lee. (2009) Pharmacokinetics of Acetaminophen-Protein Adducts in Adults with Acetaminophen Overdose and Acute Liver Failure. Drug Metabolism and Disposition 37:8, pages 1779-1784.
Crossref
K. N. Woodward. 2009. Veterinary Pharmacovigilance. Veterinary Pharmacovigilance 423 452 .
Linda J. Chun, Myron J. Tong, Ronald W. Busuttil & Jonathan R. Hiatt. (2009) Acetaminophen Hepatotoxicity and Acute Liver Failure. Journal of Clinical Gastroenterology 43:4, pages 342-349.
Crossref
Hui‐Hui Tan, Charissa Y. Chang & Paul Martin. (2009) Acetaminophen Hepatotoxicity: Current Management. Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine 76:1, pages 75-83.
Crossref
Giovanni Tarantino, Matteo Nicola Dario Di Minno & Domenico Capone. (2009) Drug-induced liver injury: Is it somehow foreseeable?. World Journal of Gastroenterology 15:23, pages 2817.
Crossref
Robert J. Fontana, Paul B. Watkins, Herbert L. Bonkovsky, Naga Chalasani, Timothy Davern, Jose Serrano & James Rochon. (2009) Drug-Induced Liver Injury Network (DILIN) Prospective Study. Drug Safety 32:1, pages 55-68.
Crossref
C. D. Oscier & Q. J. W. Milner. (2009) Peri-operative use of paracetamol. Anaesthesia 64:1, pages 65-72.
Crossref
Jeremy M. Johnson. (2008) Over-the-Counter Overdoses. Advanced Emergency Nursing Journal 30:4, pages 369-378.
Crossref
Geoffrey C. Nguyen, Justina Sam & Paul J. Thuluvath. (2008) Hepatitis C is a predictor of acute liver injury among hospitalizations for acetaminophen overdose in the United States: A nationwide analysis. Hepatology 48:4, pages 1336-1341.
Crossref
Ian M. Copple, Christopher E. Goldring, Rosalind E. Jenkins, Alvin J. L. Chia, Laura E. Randle, John D. Hayes, Neil R. Kitteringham & B. Kevin Park. (2008) The hepatotoxic metabolite of acetaminophen directly activates the Keap1-Nrf2 cell defense system. Hepatology 48:4, pages 1292-1301.
Crossref
Silas W Smith, Mary Ann Howland, Robert S Hoffman & Lewis S Nelson. (2008) Acetaminophen Overdose with Altered Acetaminophen Pharmacokinetics and Hepatotoxicity Associated with Premature Cessation of Intravenous N-Acetylcysteine Therapy. Annals of Pharmacotherapy 42:9, pages 1333-1339.
Crossref
Scott Saccomano & Deborah A. DeLuca. (2008) Too toxic. Nursing Management 39:9, pages 32A-32H.
Crossref
Guven Kuvandik, Mehmet Duru, Ahmet Nacar, Zafer Yonden, Rami Helvaci, Ahmet Koc, Tolunay Kozlu, Hasan Kaya & Sadik Sog?t. (2008) Effects of Erdosteine on Acetaminophen-induced Hepatotoxicity in Rats. Toxicologic Pathology 36:5, pages 714-719.
Crossref
Robert J. Fontana. (2008) Acute Liver Failure Including Acetaminophen Overdose. Medical Clinics of North America 92:4, pages 761-794.
Crossref
Anne M. Larson. (2008) Acute Liver Failure. Disease-a-Month 54:7, pages 457-485.
Crossref
Athena F. Zuppa & Jeffrey S. Barrett. (2008) Pharmacokinetics and Pharmacodynamics in the Critically Ill Child. Pediatric Clinics of North America 55:3, pages 735-755.
Crossref
J. J. VAN VEEN, D. C. GLEESON & M. MAKRIS. (2008) Paracetamol/acetaminophen usage in haemophilia: more caution needed?. Haemophilia 14:3, pages 434-435.
Crossref
Fahad M. Ali, Edward W. Boyer & Steven B. Bird. (2008) Estimated risk of hepatotoxicity after an acute acetaminophen overdose in alcoholics. Alcohol 42:3, pages 213-218.
Crossref
Darren M RobertsNicholas A Buckley. (2008) Prolonged absorption and delayed peak paracetamol concentration following poisoning with extended‐release formulation. Medical Journal of Australia 188:5, pages 310-311.
Crossref
Elliot V. Hersh & Paul A. Moore. (2008) Adverse drug interactions in dentistry. Periodontology 2000 46:1, pages 109-142.
Crossref
Scott Saccomano & Deborah A. DeLuca. (2008) Too toxic. Nursing Critical Care 3:1, pages 36-43.
Crossref
Harold I. Zeliger. 2008. Human Toxicology of Chemical Mixtures. Human Toxicology of Chemical Mixtures 495 506 .
Shahrokh C. Bagheri. 2008. Clinical Review of Oral and Maxillofacial Surgery. Clinical Review of Oral and Maxillofacial Surgery 21 43 .
Robert P Myers, Bing Li, Andrew Fong, Abdel Aziz M Shaheen & Hude Quan. (2007) Hospitalizations for acetaminophen overdose: a Canadian population-based study from 1995 to 2004. BMC Public Health 7:1.
Crossref
Scott Saccomano & Deborah A. DeLuca. (2007) Too toxic. Men in Nursing 2:5, pages 42-48.
Crossref
Richard C. Dart & Barry H. Rumack. (2007) Patient-Tailored Acetylcysteine Administration. Annals of Emergency Medicine 50:3, pages 280-281.
Crossref
Henry A. Spiller & Tama S. Sawyer. (2007) Impact of Activated Charcoal After Acute Acetaminophen Overdoses Treated with N-Acetylcysteine. The Journal of Emergency Medicine 33:2, pages 141-144.
Crossref
Anne M. Larson. (2007) Acetaminophen Hepatotoxicity. Clinics in Liver Disease 11:3, pages 525-548.
Crossref
Sidney Nelson & Sam Bruschi. 2007. Drug-Induced Liver Disease, Second Edition. Drug-Induced Liver Disease, Second Edition 353 388 .
C K Gelotte, J F Auiler, J M Lynch, A R Temple & J T Slattery. (2007) Disposition of Acetaminophen at 4, 6, and 8 g/day for 3 Days in Healthy Young Adults. Clinical Pharmacology & Therapeutics 81:6, pages 840-848.
Crossref

Displaying 200 of 235 citing articles. Use the download link below to view the full list of citing articles.

Download full citations list

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.