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Research Article

Polymorphisms of Paraoxonase (PON1) and Their Significance in Clinical Toxicology of Organophosphates

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Pages 37-45 | Published online: 19 Feb 2003

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Estefania Gastaldello Moreira, Dalmo Guilherme Correia, Kamila Landucci Bonifácio, Juliana Brum de Moraes, Fernanda Liboni Cavicchioli, Carolina Sampaio Nunes, Sandra Odebrecht Vargas Nunes, Heber Odebrecht Vargas, Décio Sabbatini Barbosa & Michael Maes. (2019) Lowered PON1 activities are strongly associated with depression and bipolar disorder, recurrence of (hypo)mania and depression, increased disability and lowered quality of life. The World Journal of Biological Psychiatry 20:5, pages 368-380.
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Daniel L. Sudakin & David L. Stone. (2011) Dialkyl phosphates as biomarkers of organophosphates: The current divide between epidemiology and clinical toxicology. Clinical Toxicology 49:9, pages 771-781.
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Bülent Sözmen, Şule Peker, Ümmühan Kaya, Mualla Erkan & Eser Yildirim Sözmen. (2007) Markers of Long-Term Exposure to Organophosphorus Pesticides in Farmers Who Work in Viniculture and Tobacco Production in Turkey. Toxicology Mechanisms and Methods 17:7, pages 379-384.
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Lucio G. Costa, Toby B. Cole, Jacqueline Garrick, Judit Marsillach & Clement E. Furlong. 2020. Handbook of Toxicology of Chemical Warfare Agents. Handbook of Toxicology of Chemical Warfare Agents 1179 1190 .
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Michele Teodoro, Giusi Briguglio, Concettina Fenga & Chiara Costa. (2019) Genetic polymorphisms as determinants of pesticide toxicity: Recent advances. Toxicology Reports 6, pages 564-570.
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Tracy Glass, Mohamed A. Dalvie, Zelda Holtman, Anna A. Vorster, Rajkumar S. Ramesar & Leslie London. (2018) DNA variants and organophosphate neurotoxicity among emerging farmers in the Western Cape of South Africa. American Journal of Industrial Medicine 61:1, pages 11-20.
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Ken Declerck, Sylvie Remy, Christine Wohlfahrt-Veje, Katharina M. Main, Guy Van Camp, Greet Schoeters, Wim Vanden Berghe & Helle R. Andersen. (2017) Interaction between prenatal pesticide exposure and a common polymorphism in the PON1 gene on DNA methylation in genes associated with cardio-metabolic disease risk—an exploratory study. Clinical Epigenetics 9:1.
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M. Macharia, A. P. Kengne, D. M. Blackhurst, R. T. Erasmus & T. E. Matsha. (2014) Paraoxonase1 Genetic Polymorphisms in a Mixed Ancestry African Population. Mediators of Inflammation 2014, pages 1-9.
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Slavica Vučinić, Biljana Antonijević & Dragica Brkić. 2014. Basic and Clinical Toxicology of Organophosphorus Compounds. Basic and Clinical Toxicology of Organophosphorus Compounds 213 244 .
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