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Research Article

Thymoquinone Is a Potent Superoxide Anion Scavenger

, Ph.D., , &
Pages 87-98 | Published online: 28 Apr 2003

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (18)

Yousef Baghcheghi, Farimah Beheshti, Fatemeh Seyedi, Mahmoud Hosseini & Mahdiyeh Hedayati-Moghadam. (2022) Thymoquinone improved redox homeostasis in the heart and aorta of hypothyroid rats. Clinical and Experimental Hypertension 44:7, pages 656-662.
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Osama A Badary, Marwa S Hamza & Rajiv Tikamdas. (2021) Thymoquinone: A Promising Natural Compound with Potential Benefits for COVID-19 Prevention and Cure. Drug Design, Development and Therapy 15, pages 1819-1833.
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Mohammad Rafiq Wani & G. G. Hammad Ahmad Shadab. (2021) Antioxidant thymoquinone and eugenol alleviate TiO2 nanoparticle-induced toxicity in human blood cells in vitro. Toxicology Mechanisms and Methods 31:8, pages 619-629.
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M. K. Ozer, S. Bilgic, I. Armagan & M. Savran. (2020) Thymoquinone protection from amikacin induced renal injury in rats. Biotechnic & Histochemistry 95:2, pages 129-136.
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Elif Demir, Seyithan Taysi, Hasan Ulusal, Davut Sinan Kaplan, Kadir Cinar & Mehmet Tarakcioglu. (2020) Nigella sativa oil and thymoquinone reduce oxidative stress in the brain tissue of rats exposed to total head irradiation . International Journal of Radiation Biology 96:2, pages 228-235.
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Amin F. Majdalawieh, Muneera W. Fayyad & Gheyath K. Nasrallah. (2017) Anti-cancer properties and mechanisms of action of thymoquinone, the major active ingredient of Nigella sativa. Critical Reviews in Food Science and Nutrition 57:18, pages 3911-3928.
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Ambreena Riyaz, Shahid Nazir, Mohammad Khushtar, Anuradha Mishra, Yasmeen Jahan & Asad Ahmad. (2017) Effect of Nigella sativa L. seed extract on cisplatin-induced delay in gastric emptying in Sprague-Dawley rats. Natural Product Research 31:5, pages 588-592.
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Dogukan Canayakin, Yasin Bayir, Nurcan Kilic Baygutalp, Esen Sezen Karaoglan, Hasan Tarik Atmaca, Fatma Betul Kocak Ozgeris, Mevlut Sait Keles & Zekai Halici. (2016) Paracetamol-induced nephrotoxicity and oxidative stress in rats: the protective role of Nigella sativa. Pharmaceutical Biology 54:10, pages 2082-2091.
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Mohammed M. H. Al-Gayyar, Hanan M. Hassan, Abdullah Alyoussef, Ahmed Abbas, Mohamed M. Darweish & Amany A. El-Hawwary. (2016) Nigella sativa oil attenuates chronic nephrotoxicity induced by oral sodium nitrite: Effects on tissue fibrosis and apoptosis. Redox Report 21:2, pages 50-60.
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Nafise Tabasi, Mahmoud Mahmoudi, Maryam Rastin, Hamid Reza Sadeghnia, Mojtaba HosseinPour Mashhadi, Shahrzad Zamani Taghizade Rabe & Abolfazl Khajavi Rad. (2015) Cytotoxic and apoptogenic properties of Nigella sativa and thymoquinone, its constituent, in human renal cell carcinoma are comparable with cisplatin. Food and Agricultural Immunology 26:1, pages 138-156.
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Sinan Ince, Ismail Kucukkurt, Hasan Huseyin Demirel, Ruhi Turkmen, Fahriye Zemheri & Erten Akbel. (2013) The role of thymoquinone as antioxidant protection on oxidative stress induced by imidacloprid in male and female Swiss albino mice. Toxicological & Environmental Chemistry 95:2, pages 318-329.
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Majed M. AbuKhader, Samar H. Khater & Hisham Y. Al-Matubsi. (2013) Acute effects of thymoquinone on the pregnant rat and embryo-fetal development. Drug and Chemical Toxicology 36:1, pages 27-34.
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Masood Sadiq Butt & Muhammad Tauseef Sultan. (2010) Nigella sativa: Reduces the Risk of Various Maladies. Critical Reviews in Food Science and Nutrition 50:7, pages 654-665.
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NagwaM. El-Sawi & HanaM. Gashlan. (2010) Effect of Nigella sativa Oil and Activated Charcoal as Antioxidant on Verrucarin J induced Hepatotoxicity in Male Rats. Journal of Applied Animal Research 37:2, pages 285-288.
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K. Dhalwal, Y.S. Deshpande, A.P. Purohit & S.S. Kadam. (2005) Evaluation of the Antioxidant Activity of Sida cordifolia.. Pharmaceutical Biology 43:9, pages 754-761.
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Mahmoud Mansour & Susanne Tornhamre. (2004) Inhibition of 5-lipoxygenase and Leukotriene C4 Synthase in Human Blood Cells by Thymoquinone. Journal of Enzyme Inhibition and Medicinal Chemistry 19:5, pages 431-436.
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Donovan A. McGrowder, Fabian G. Miller, Chukwuemeka R. Nwokocha, Melisa S. Anderson, Cameil Wilson-Clarke, Kurt Vaz, Lennox Anderson-Jackson & Jabari Brown. (2020) Medicinal Herbs Used in Traditional Management of Breast Cancer: Mechanisms of Action. Medicines 7:8, pages 47.
Crossref
Mehtap Savran, Halil Ascı, İlkay Armagan, Yalcin Erzurumlu, Sebile Azırak, Mehmet Kaya Ozer, Sedat Bilgic & Deniz Tastemir Korkmaz. (2020) Thymoquinone could be protective against valproic acid‐induced testicular toxicity by antioxidant and anti‐inflammatory mechanisms. Andrologia 52:7.
Crossref
Patience Mapule Thabede, Ntaote David Shooto, Thokozani Xaba & Eliazer Bobby Naidoo. (2020) Adsorption studies of toxic cadmium(II) and chromium(VI) ions from aqueous solution by activated black cumin (Nigella sativa) seeds. Journal of Environmental Chemical Engineering 8:4, pages 104045.
Crossref
Mohamed A. Kandeil, Safaa B. Gomaa & Mohamed O. Mahmoud. (2020) The effect of some natural antioxidants against cisplatin-induced neurotoxicity in rats: behavioral testing. Heliyon 6:8, pages e04708.
Crossref
Moyosore J. Adegbeye, Mona M. M. Y. Elghandour, Tolulope O. Faniyi, Nallely Rivero Perez, Alberto Barbabosa-Pilego, Adrian Zaragoza-Bastida & Abdelfattah Z. M. Salem. (2018) Antimicrobial and antihelminthic impacts of black cumin, pawpaw and mustard seeds in livestock production and health. Agroforestry Systems 94:4, pages 1255-1268.
Crossref
Heena Tabassum & Iffat Z. Ahmad. (2020) Molecular Docking and Dynamics Simulation Analysis of Thymoquinone and Thymol Compounds from Nigella sativa L. that Inhibits P38 Protein: Probable Remedies for Hepatocellular Carcinoma. Medicinal Chemistry 16:3, pages 350-357.
Crossref
Fereidoon Shahidi, HYing Joy Zhong & Zhuliang Tan. 2005. Bailey's Industrial Oil and Fat Products. Bailey's Industrial Oil and Fat Products 1 23 .
Fereidoon Shahidi, HYing Joy Zhong & Priyatharini Ambigaipalan. 2005. Bailey's Industrial Oil and Fat Products. Bailey's Industrial Oil and Fat Products 1 21 .
Hamzeh Alkhatib, SaeidMezail Mawazi, SinanMohammed Abdullah Al-Mahmood, Ahmad Zaiter & AbdAlmonem Doolaanea. (2020) Thymoquinone content in marketed black seed oil in Malaysia. Journal of Pharmacy And Bioallied Sciences 12:3, pages 284.
Crossref
Fatemeh Forouzanfar & Hossein Hosseinzadeh. 2020. Nuts and Seeds in Health and Disease Prevention. Nuts and Seeds in Health and Disease Prevention 127 146 .
Amiza Hamdan, Ruszymah Haji Idrus & Mohd Helmy Mokhtar. (2019) Effects of Nigella Sativa on Type-2 Diabetes Mellitus: A Systematic Review. International Journal of Environmental Research and Public Health 16:24, pages 4911.
Crossref
Sabrina Bimonte, Vittorio Albino, Antonio Barbieri, Maria Luisa Tamma, Aurelio Nasto, Raffaele Palaia, Carlo Molino, Paolo Bianco, Andrea Vitale, Rita Schiano, Aldo Giudice & Marco Cascella. (2019) Dissecting the roles of thymoquinone on the prevention and the treatment of hepatocellular carcinoma: an overview on the current state of knowledge. Infectious Agents and Cancer 14:1.
Crossref
Henna Roshini Alexander, Sharifah Sakinah Syed Alwi, Latifah Saiful Yazan, Fatin Hanani Zakarial Ansar & Yong Sze Ong. (2019) Migration and Proliferation Effects of Thymoquinone-Loaded Nanostructured Lipid Carrier (TQ-NLC) and Thymoquinone (TQ) on In Vitro Wound Healing Models . Evidence-Based Complementary and Alternative Medicine 2019, pages 1-14.
Crossref
Ananya Singh, Farhan Ahmad, Priti Bajpai, Tarique Mahmood Ansari & Aisha Kamal. (2019) Cyanosomes: A pilot study. Chemistry and Physics of Lipids 224, pages 104728.
Crossref
İbrahim Halil Yıldırım, Ali Ahmed Azzawri & Tuğçe Duran. (2019) Thymoquinone induces apoptosis via targeting the Bax/BAD and Bcl-2 pathway in breast cancer cells. Dicle Tıp Dergisi, pages 411-417.
Crossref
Waleed AL-Ansi, Amer Ali Mahdi, Qais Ali Al-Maqtari, Mingcong Fan, Li Wang, Yan Li, Haifeng Qian & Hui Zhang. (2019) Evaluating the role of microwave-baking and fennel (Foeniculum vulgare L.)/nigella (Nigella sativa L.) on acrylamide growth and antioxidants potential in biscuits. Journal of Food Measurement and Characterization 13:3, pages 2426-2437.
Crossref
Javad Saffari_Chaleshtori, Ehsan Heidari-SureshjaniFahimeh MoradiEsfandiar Heidarian. (2019) The Effects of Thymoquinone on Viability, and Anti-apoptotic Factors (BCL-XL, BCL-2, MCL-1) in Prostate Cancer (PC3) Cells: An In Vitro and Computer-Simulated Environment Study. Advanced Pharmaceutical Bulletin 9:3, pages 490-496.
Crossref
Sahar Fanoudi, Mohaddeseh S. Alavi, Mahmoud Hosseini & Hamid R. Sadeghnia. (2019) Nigella sativa and thymoquinone attenuate oxidative stress and cognitive impairment following cerebral hypoperfusion in rats. Metabolic Brain Disease 34:4, pages 1001-1010.
Crossref
Kürşad YAPAR, Kültiğin ÇAVUŞOĞLU, Emine YALÇIN, Ali ACAR & Güray DEMİRTAŞ. (2019) In Vivo Protective Role of Nigella sativa L. Against Pb(NO3)2 Induced Toxicity. Düzce Üniversitesi Bilim ve Teknoloji Dergisi 7:3, pages 1279-1289.
Crossref
Yasmina K. Mahmoud & Heba M.A. Abdelrazek. (2019) Cancer: Thymoquinone antioxidant/pro-oxidant effect as potential anticancer remedy. Biomedicine & Pharmacotherapy 115, pages 108783.
Crossref
Biliu Wu, Jiajun Yang, Jianjian Zhang, Zheng Li, Hua Li & Xiao-Feng Yang. (2019) A ratiometric fluorescent probe for the detection of endogenous hydroxyl radicals in living cells. Talanta 196, pages 317-324.
Crossref
Mothanna Sadiq Al-Qubaisi, Abdullah Rasedee, Moayad Husein Flaifel, Eltayeb E.M. Eid, Samer Hussein-Al-Ali, Fatah H. Alhassan, Ashraf M. Salih, Mohd Zobir Hussein, Zulkarnain Zainal, Dahiru Sani, Abdulmajeed Hammadi Aljumaily & Mohammed Ibrahim Saeed. (2019) Characterization of thymoquinone/hydroxypropyl-β-cyclodextrin inclusion complex: Application to anti-allergy properties. European Journal of Pharmaceutical Sciences 133, pages 167-182.
Crossref
Dorina Casoni, Ileana Maria Simion & Costel Sârbu. (2019) A comprehensive classification of edible oils according to their radical scavenging spectral profile evaluated by advanced chemometrics. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 213, pages 204-209.
Crossref
Raviella Zgheib, Marc El-Beyrouthy, Sylvain Chaillou, Naim Ouaini, Douglas Rutledge, Didier Stien, Amine Kassouf, Marco Leonti & Marcello Iriti. (2019) Chemical Variability of the Essential Oil of Origanum ehrenbergii Boiss. from Lebanon, Assessed by Independent Component Analysis (ICA) and Common Component and Specific Weight Analysis (CCSWA). International Journal of Molecular Sciences 20:5, pages 1026.
Crossref
Zahra Karimi, Adel Mirza Alizadeh, Jafar Ezzati Nazhad Dolatabadi & Parvin Dehghan. (2019) Nigella sativa and its Derivatives as Food Toxicity Protectant Agents. Advanced Pharmaceutical Bulletin 9:1, pages 22-37.
Crossref
Arshad Husain Rahmani, Ahmad Almatroudi, Ali Yousif Babikr, Amjad Ali Khan & Mohammed A. Alsahli. (2019) Thymoquinone, an Active Constituent of Black Seed Attenuates CCl4 Induced Liver Injury in Mice via Modulation of Antioxidant Enzymes, PTEN, P53 and VEGF Protein. Open Access Macedonian Journal of Medical Sciences 7:3, pages 311-317.
Crossref
H.A. Aisa, Xuelei Xin & Dan Tang. 2019. Bioactive Food as Dietary Interventions for Diabetes. Bioactive Food as Dietary Interventions for Diabetes 629 640 .
Omprakash H. Nautiyal. 2019. Fruit Oils: Chemistry and Functionality. Fruit Oils: Chemistry and Functionality 839 857 .
Aymen Mabrouk. (2018) Thymoquinone attenuates lead‐induced nephropathy in rats. Journal of Biochemical and Molecular Toxicology 33:1.
Crossref
Jingyi Xu, Liyue Zhu, Hongyang Liu, Mengye Li, Yingshu Liu, Fan Yang & Zuowei Pei. (2018) Thymoquinone reduces cardiac damage caused by hypercholesterolemia in apolipoprotein E-deficient mice. Lipids in Health and Disease 17:1.
Crossref
Abdul G. Miah, Roslyn Bathgate, Koh‐ichi Hamano & Ummay Salma. (2018) Effects of pre‐freeze Nigella sativa oil supplementation on cryosurvival of ovine spermatozoa . Reproduction in Domestic Animals 53:6, pages 1424-1433.
Crossref
Ajaz Ahmad, Mohammad Raish, Khalid M. Alkharfy, Ibrahim A. Alsarra, Altaf Khan, Abdul Ahad, Basit L. Jan & Faiyaz Shakeel. (2018) Solubility, solubility parameters and solution thermodynamics of thymoquinone in different mono solvents. Journal of Molecular Liquids 272, pages 912-918.
Crossref
Mary Gulumian, Ewura Seidu Yahaya & Vanessa Steenkamp. (2018) African Herbal Remedies with Antioxidant Activity: A Potential Resource Base for Wound Treatment. Evidence-Based Complementary and Alternative Medicine 2018, pages 1-58.
Crossref
Saba Hajizadeh, Bahman Parizadian Kavan, Heshmatollah Khosravinia & Babak Masouri. (2018) Effects of Dietary Levels of Black Cumin (Nigella Sativa L.) Powder on Performance, Yolk Cholesterol Content and Egg Oxidative Stability in Laying Hens. Research on Animal Production 9:21, pages 18-25.
Crossref
Mohammed Shariq Iqbal, Ausaf Ahmad & Brijesh Pandey. (2018) Solvent based optimization for extraction and stability of thymoquinone from Nigella sativa Linn. and its quantification using RP-HPLC. Physiology and Molecular Biology of Plants 24:6, pages 1209-1219.
Crossref
Mohsen G. Alrashedi, Ahmed S. Ali, Soad S. Ali & Lateef M. Khan. (2018) Impact of thymoquinone on cyclosporine A pharmacokinetics and toxicity in rodents. Journal of Pharmacy and Pharmacology 70:10, pages 1332-1339.
Crossref
Ahlem Bouhlel, Mohamed Bejaoui, Ismail Ben Mosbah, Najet Hadj Abdallah, Catherine Ribault, Roselyne Viel, Hassen Hentati, Anne Corlu & Hassen Ben Abdennebi. (2018) Thymoquinone protects rat liver after partial hepatectomy under ischaemia/reperfusion through oxidative stress and endoplasmic reticulum stress prevention. Clinical and Experimental Pharmacology and Physiology 45:9, pages 943-951.
Crossref
Hina Aslam, Muhammad Shahzad, Arham Shabbir & Sabeen Irshad. (2018) Immunomodulatory effect of thymoquinone on atopic dermatitis. Molecular Immunology 101, pages 276-283.
Crossref
Mina Darand, Seyed Moayed Alavian & Azita Hekmatdoost. (2018) Nigella sativa and Non-Alcoholic Fatty Liver Disease: A Review of the Current Evidence. Hepatitis Monthly In Press:In Press.
Crossref
N. Kehili, S. Saka & O. Aouacheri. (2018) L’effet phytoprotecteur de la nigelle ( Nigella sativa ) contre la toxicité induite par le cadmium chez les rats . Phytothérapie 16:4, pages 194-203.
Crossref
Ali Rajabpour Sanati, Tahereh Farkhondeh & Saeed Samarghandian. (2018) Antidotal effects of thymoquinone against neurotoxic agents. Interdisciplinary Toxicology 11:2, pages 122-128.
Crossref
M. A. Awan, S. Akhter, A. U. Husna, M. S. Ansari, B. A. Rakha, A. Azam & S. Qadeer. (2018) Antioxidant activity of Nigella sativa Seeds Aqueous Extract and its use for cryopreservation of buffalo spermatozoa . Andrologia 50:6, pages e13020.
Crossref
Mohamed M. Abdel-Daim, Hazem M. Shaheen, Abdelrahman Ibrahim Abushouk, Eman A. Toraih, Manal S. Fawzy, Wafa S. Alansari, Lotfi Aleya & Simona Bungau. (2018) Thymoquinone and diallyl sulfide protect against fipronil-induced oxidative injury in rats. Environmental Science and Pollution Research 25:24, pages 23909-23916.
Crossref
Y. R. Shahin, N. M. Elguindy, A. Abdel Bary & M. Balbaa. (2018) The protective mechanism of Nigella sativa against diethylnitrosamine-induced hepatocellular carcinoma through its antioxidant effect and EGFR/ERK1/2 signaling . Environmental Toxicology 33:8, pages 885-898.
Crossref
Ahlam Alhusaini, Laila Faddaa, Hanaa M. Ali, Iman Hassan, Nagla F. El Orabi & Yieldiz Bassiouni. (2018) Amelioration of the Protein Expression of Cox2, NF κ B, and STAT-3 by Some Antioxidants in the Liver of Sodium Fluoride–Intoxicated Rats . Dose-Response 16:3, pages 155932581880015.
Crossref
Makini K. Cobourne-Duval, Equar Taka, Patricia Mendonca & Karam F.A. Soliman. (2018) Thymoquinone increases the expression of neuroprotective proteins while decreasing the expression of pro-inflammatory cytokines and the gene expression NFκB pathway signaling targets in LPS/IFNγ -activated BV-2 microglia cells. Journal of Neuroimmunology 320, pages 87-97.
Crossref
Fakiha Firdaus, Mohd Faraz Zafeer, Masood Ahmad & Mohammad Afzal. (2018) Anxiolytic and anti-inflammatory role of thymoquinone in arsenic-induced hippocampal toxicity in Wistar rats. Heliyon 4:6, pages e00650.
Crossref
Ibram Amin Fouad, Nadia Mohamed Sharaf, Ragwa Mansour Abdelghany & Nesrine Salah El Dine El Sayed. (2018) Neuromodulatory Effect of Thymoquinone in Attenuating Glutamate-Mediated Neurotoxicity Targeting the Amyloidogenic and Apoptotic Pathways. Frontiers in Neurology 9.
Crossref
Muthu K. Shanmugam, Frank Arfuso, Alan Prem Kumar, Lingzhi Wang, Boon Cher Goh, Kwang Seok Ahn, Anupam Bishayee & Gautam Sethi. (2018) Modulation of diverse oncogenic transcription factors by thymoquinone, an essential oil compound isolated from the seeds of Nigella sativa Linn. Pharmacological Research 129, pages 357-364.
Crossref
Merve Beker, Tuğçe Dallı & Birsen Elibol. (2018) Thymoquinone Can Improve Neuronal Survival and Promote Neurogenesis in Rat Hippocampal Neurons. Molecular Nutrition & Food Research 62:5, pages 1700768.
Crossref
Marco Cascella, Sabrina Bimonte, Antonio Barbieri, Vitale Del Vecchio, Maria Rosaria Muzio, Andrea Vitale, Giulio Benincasa, Anna Bella Ferriello, Amalia Azzariti, Claudio Arra & Arturo Cuomo. (2018) Dissecting the Potential Roles of Nigella sativa and Its Constituent Thymoquinone on the Prevention and on the Progression of Alzheimer's Disease. Frontiers in Aging Neuroscience 10.
Crossref
Amaj A. Laskar. 2018. Molecular and Therapeutic actions of Thymoquinone. Molecular and Therapeutic actions of Thymoquinone 65 74 .
Arif Khan. 2018. Molecular and Therapeutic actions of Thymoquinone. Molecular and Therapeutic actions of Thymoquinone 41 56 .
Rozaina Ahmad, Noor Haida Mohd Kaus & Shahrul Hamid. 2020. Cancer Biology and Advances in Treatment. Cancer Biology and Advances in Treatment 65 82 .
Zeba Farooqui, Faaiza Shahid, Aijaz Ahmed Khan & Farah Khan. (2017) Oral administration of Nigella sativa oil and thymoquinone attenuates long term cisplatin treatment induced toxicity and oxidative damage in rat kidney. Biomedicine & Pharmacotherapy 96, pages 912-923.
Crossref
Zeba Farooqui, Faaiza Shahid, Subuhi Abidi, Iqbal Parwez & Farah Khan. (2017) Oral thymoquinone administration ameliorates: the effect of cisplatin on brush border membrane enzymes, energy metabolism, and redox status in rat kidney. Naunyn-Schmiedeberg's Archives of Pharmacology 390:12, pages 1271-1284.
Crossref
Omar M. Alaufi, Abdulwahab Noorwali, Fatheya Zahran, Ahmed M. Al-Abd & Safia Al-Attas. (2017) Cytotoxicity of thymoquinone alone or in combination with cisplatin (CDDP) against oral squamous cell carcinoma in vitro. Scientific Reports 7:1.
Crossref
Ahlem Bouhlel, Ismail Ben Mosbah, Najet Hadj Abdallah, Catherine Ribault, Roselyne Viel, Saber Mannaï, Anne Corlu & Hassen Ben Abdennebi. (2017) Thymoquinone prevents endoplasmic reticulum stress and mitochondria-induced apoptosis in a rat model of partial hepatic warm ischemia reperfusion. Biomedicine & Pharmacotherapy 94, pages 964-973.
Crossref
Tahereh Farkhondeh, Saeed Samarghandian & Abasalt Borji. (2017) An overview on cardioprotective and anti-diabetic effects of thymoquinone. Asian Pacific Journal of Tropical Medicine 10:9, pages 849-854.
Crossref
Dimitrios Tsimogiannis, Andreas Bimpilas & Vassiliki Oreopoulou. (2017) DPPH radical scavenging and mixture effects of plant o ‐diphenols and essential oil constituents . European Journal of Lipid Science and Technology 119:9, pages 16003473.
Crossref
M. R. Islam, Jaan S. Islam & G.M. Zatzman. 2017. The Greening of Pharmaceutical Engineering. The Greening of Pharmaceutical Engineering 423 494 .
Erdem Kamil Ozer, Mustafa Tugrul Goktas, Aysun Toker, Sultan Pehlivan, Hulagu Bariskaner, Ceyhan Ugurluoglu & Alper Bektas Iskit. (2017) Thymoquinone protects against the sepsis induced mortality, mesenteric hypoperfusion, aortic dysfunction and multiple organ damage in rats. Pharmacological Reports 69:4, pages 683-690.
Crossref
Shengliang Hu, Xuejun Han, Yufeng Zhou, Chaorui Xue, Qing Chang & Jinlong Yang. (2017) Hybrid carbon dot/Ni 3 S 2 architecture supported on nickel foam for effective light collection and conversion. Chemical Engineering Journal 321, pages 608-613.
Crossref
Marco Cascella, Giuseppe Palma, Antonio Barbieri, Sabrina Bimonte, Nagoth Amruthraj, Maria Muzio, Vitale del Vecchio, Domenica Rea, Michela Falco, Antonio Luciano, Claudio Arra & Arturo Cuomo. (2017) Role of Nigella sativa and Its Constituent Thymoquinone on Chemotherapy-Induced Nephrotoxicity: Evidences from Experimental Animal Studies. Nutrients 9:6, pages 625.
Crossref
Ahmed Benharref, Rabia Fdil, Fadwa El Hanbali, Abdellah Zeroual, Mohamed Dakir & Noureddine Mazoir. (2019) A New Monoterpene Isolated from Nigella sativa Essential Oil . Natural Product Communications 12:6, pages 1934578X1701200.
Crossref
Nesreen Moustafa Omar & Mohammed Amin Mohammed. (2017) The impact of black seed oil on tramadol-induced hepatotoxicity: Immunohistochemical and ultrastructural study. Acta Histochemica 119:5, pages 543-554.
Crossref
S.N. Saxena, S.S. Rathore, Y. Diwakar, R.K. Kakani, K. Kant, P.N. Dubey, R.K. Solanki, L.K. Sharma, D. Agarwal & S. John. (2017) Genetic diversity in fatty acid composition and antioxidant capacity of Nigella sativa L. genotypes. LWT 78, pages 198-207.
Crossref
Rayees Ul Islam, Mohammad Ali Khan & Shahid Ul Islam. (2017) Plant Derivatives as Promising Materials for Processing and Packaging of Meat-Based Products - Focus on Antioxidant and Antimicrobial Effects. Journal of Food Processing and Preservation 41:2, pages e12862.
Crossref
N. Kehili, S. Saka & O. Aouacheri. (2017) L’effet phytoprotecteur de la nigelle (Nigella sativa) contre la toxicité induite par le cadmium chez les ratsThe phytoprotective effect of nigella (Nigella sativa) against the toxicity induced by cadmium in rats. Phytothérapie.
Crossref
Mahmut Ogurlu, Ozlem Celebi Erdivanli, Levent Tumkaya, Abdulkadir Ozgur, Zerrin Ozergin Coskun, Suat Terzi, Munir Demirci & Engin Dursun. (2016) The therapeutic effect of thymoquinone on acoustic trauma-induced hearing loss in rats. European Archives of Oto-Rhino-Laryngology 274:2, pages 743-749.
Crossref
Siti Mariyah Ulfa, Shoimatus Sholikhah & Edi Priyo Utomo. Synthesis of Thymoquinone derivatives and its activity analysis: In-silico approach. Synthesis of Thymoquinone derivatives and its activity analysis: In-silico approach.
Zuowei Pei, Liyue Zhu, Yingshu Liu, Nan Li, Guang Yang & Hongyang Liu. (2017) Thymoquinone reduces kidney damage in apolipoprotein E-deficient mice fed a high-cholesterol diet. RSC Advances 7:83, pages 53002-53009.
Crossref
Temelkan Bakır, İnci Sönmezoglu & Reşat Apak. (2016) Quantification of Antioxidant Ability Against Lipid Peroxidation with an ‘Area Under Curve’ Approach. Journal of the American Oil Chemists' Society 94:1, pages 77-88.
Crossref
Makini K. Cobourne-Duval, Equar Taka, Patricia Mendonca, David Bauer & Karam F. A. Soliman. (2016) The Antioxidant Effects of Thymoquinone in Activated BV-2 Murine Microglial Cells. Neurochemical Research 41:12, pages 3227-3238.
Crossref
A. Naga Mahmoud, Shata Ahmad & Ahmed El kattawy Hany. (2016) Phenytoin: Is it genotoxic in isolated cultured human lymphocytes without metabolic activation by S9?. African Journal of Pharmacy and Pharmacology 10:41, pages 865-872.
Crossref
G. G. Martinovich, I. V. Martinovich, A. V. Vcherashniaya, O. I. Shadyro & S. N. Cherenkevich. (2017) Thymoquinone, a biologically active component of Nigella sativa, induces mitochondrial production of reactive oxygen species and programmed death of tumor cells. Biophysics 61:6, pages 963-970.
Crossref
Saima Tariq, Tariq Masud, Samina Roohi & Shagufta Zafar Qureshi. (2016) Radiosynthesis, biodistribution and scintigraphic evaluation of 99mTc–thymoquinone against Helicobacter Pylori. Journal of Radioanalytical and Nuclear Chemistry 310:2, pages 751-760.
Crossref
Qing-Bao Zhang, Yong-Liang Ban, Da-Gang Zhou, Pan-Pan Zhou, Li-Zhu Wu & Qiang Liu. (2016) Preparation of α-Acyloxy Ketones via Visible-Light-Driven Aerobic Oxo-Acyloxylation of Olefins with Carboxylic Acids. Organic Letters 18:20, pages 5256-5259.
Crossref
Niyaz Ahmad, Rizwan Ahmad, Atta Abbas Naqvi, Md Aftab Alam, Mohammad Ashafaq, Mohd Samim, Zeenat Iqbal & Farhan Jalees Ahmad. (2016) Rutin-encapsulated chitosan nanoparticles targeted to the brain in the treatment of Cerebral Ischemia. International Journal of Biological Macromolecules 91, pages 640-655.
Crossref
Wesam Kooti, Zahra Hasanzadeh-Noohi, Naim Sharafi-Ahvazi, Majid Asadi-Samani & Damoon Ashtary-Larky. (2016) Phytochemistry, pharmacology, and therapeutic uses of black seed ( Nigella sativa ). Chinese Journal of Natural Medicines 14:10, pages 732-745.
Crossref
Murat Sereflican, Veysel Yurttas, Gulzade Ozyalvacli, Elcin Hakan Terzi, Sule Aydin Turkoglu, Serpil Yildiz, Yasin Ilgaz, Sinan Seyhan, Mesut Oral & Muharrem Dagli. (2016) The histopathological and electrophysiological effects of thymoquinone and methylprednisolone in a rabbit traumatic facial nerve paralysis model. American Journal of Otolaryngology 37:5, pages 407-415.
Crossref
Marko Jeremić, Milica Pešić, Jelena Dinić, Jasna Banković, Irena Novaković, Dejan Šegan & Dušan Sladić. (2016) Simple avarone mimetics as selective agents against multidrug resistant cancer cells. European Journal of Medicinal Chemistry 118, pages 107-120.
Crossref
Shahida A. Khan, Aziz M. Khan, Sajjad Karim, Mohammad Amjad Kamal, Ghazi A. Damanhouri & Zeenat Mirza. (2016) Panacea seed “Nigella”: A review focusing on regenerative effects for gastric ailments. Saudi Journal of Biological Sciences 23:4, pages 542-553.
Crossref
Emre Cemal GökceRamazan KahveciAysun GökceBerker CemilNurkan Aksoy, Mustafa Fevzi SargonÜçler Kısa, Bülent ErdoğanYahya Güvenç, Fatih AlagözOzan Kahveci. (2016) Neuroprotective effects of thymoquinone against spinal cord ischemia-reperfusion injury by attenuation of inflammation, oxidative stress, and apoptosis. Journal of Neurosurgery: Spine 24:6, pages 949-959.
Crossref
Aymen Mabrouk, Imen Bel Hadj Salah, Wafa Chaieb & Hassen Ben Cheikh. (2016) Protective effect of thymoquinone against lead-induced hepatic toxicity in rats. Environmental Science and Pollution Research 23:12, pages 12206-12215.
Crossref
M. Akram Khan & M. Afzal. (2016) Chemical composition of Nigella sativa Linn: Part 2 Recent advances. Inflammopharmacology 24:2-3, pages 67-79.
Crossref
Sima Bahramian, Mohammad Reza Bigdeli, Bahram Rasoulian & Mahdi Moridi Farimani. (2016) Antitumor and Antiangiogenic Effects of the Crude Oil of Nigella sativa L. in Tumor Tissues in BALB/c Mice. Zahedan Journal of Research in Medical Sciences In Press:In Press.
Crossref
Aneela Afzal & Mohammad Afzal. 2016. Oxidative Stress and Antioxidant Protection. Oxidative Stress and Antioxidant Protection 471 482 .
Alessandra Dalla Gassa, Simona Granata, Nadia Antonucci, Antonio Lupo & Gianluigi Zaza. (2018) Phytochemicals, diet and ckd-associated mitochondrial disfunction. Giornale di Tecniche Nefrologiche e Dialitiche 28:2, pages 83-90.
Crossref
Mohamed Ezzat Abd El-Hack, Mahmoud Alagawany, Mayada Ragab Farag, Ruchi Tiwari, Kumaragurubaran Karthik & Kuldeep Dhama. (2016) Nutritional, Healthical and Therapeutic Efficacy of Black Cumin (Nigella sativa) in Animals, Poultry and Humans. International Journal of Pharmacology 12:3, pages 232-248.
Crossref
Kaouthar Boudiaf, Margarita Hurtado-Nedelec, Sahra Amel Belambri, Jean-Claude Marie, Yacine Derradji, Mustapha Benboubetra, Jamel El-Benna & Pham My-Chan Dang. (2016) Thymoquinone strongly inhibits fMLF-induced neutrophil functions and exhibits anti-inflammatory properties in vivo. Biochemical Pharmacology 104, pages 62-73.
Crossref
İsmail Gülşen, Hakan Ak, Neşe Çölçimen, Hamit H. Alp, Mehmet E. Akyol, İsmail Demir, Tugay Atalay, Ragıp Balahroğlu & Murat Ç. Rağbetli. (2016) Neuroprotective Effects of Thymoquinone on the Hippocampus in a Rat Model of Traumatic Brain Injury. World Neurosurgery 86, pages 243-249.
Crossref
Zeba Farooqui, Mohammad Afsar, Sana Rizwan, Aijaz Ahmed Khan & Farah Khan. (2016) Oral administration of Nigella sativa oil ameliorates the effect of cisplatin on membrane enzymes, carbohydrate metabolism and oxidative damage in rat liver. Toxicology Reports 3, pages 328-335.
Crossref
Bhanushree Gupta, Kallol K. Ghosh & Ramesh C. Gupta. 2016. Nutraceuticals. Nutraceuticals 541 550 .
Simona Granata, Alessandra Dalla Gassa, Paola Tomei, Antonio Lupo & Gianluigi Zaza. (2015) Mitochondria: a new therapeutic target in chronic kidney disease. Nutrition & Metabolism 12:1.
Crossref
S. Asgary, A. Sahebkar & N. Goli-malekabadi. (2015) Ameliorative effects of Nigella sativa on dyslipidemia. Journal of Endocrinological Investigation 38:10, pages 1039-1046.
Crossref
Pankaj Prabhakar, K. H. Reeta, S. K. Maulik, A. K. Dinda & Y. K. Gupta. (2014) Protective effect of thymoquinone against high-fructose diet-induced metabolic syndrome in rats. European Journal of Nutrition 54:7, pages 1117-1127.
Crossref
M. Maulidiani, Bassem Y. Sheikh, Ahmed Mediani, Leong Sze Wei, Intan Safinar Ismail, Faridah Abas & Nordin H. Lajis. (2015) Differentiation of Nigella sativa seeds from four different origins and their bioactivity correlations based on NMR-metabolomics approach. Phytochemistry Letters 13, pages 308-318.
Crossref
Wessam Mohamad Abdel-Waha. (2015) Therapeutic Efficacy of Thymoquinone and Selenium Against Cyclosporine A Nephrotoxicity in Rats. Journal of Pharmacology and Toxicology 10:2, pages 60-70.
Crossref
Sara Darakhshan, Ali Bidmeshki Pour, Abasalt Hosseinzadeh Colagar & Sajjad Sisakhtnezhad. (2015) Thymoquinone and its therapeutic potentials. Pharmacological Research 95-96, pages 138-158.
Crossref
Keivan Akhtari, Keyumars Hassanzadeh, Bahareh Fakhraei, Nahid Fakhraei, Halaleh Hassanzadeh, Ghazal Akhtari, Seyed Amir Zarei & Katayoun Hassanzadeh. (2014) Mechanisms of the hydroxyl and superoxide anion radical scavenging activity and protective effect on lipid peroxidation of thymoquinone: a DFT study. Monatshefte für Chemie - Chemical Monthly 146:4, pages 601-611.
Crossref
Fadlullah AksoyRemzi DoganOrhan OzturanSelahattin TugrulBayram VeysellerOmer Faruk OzerAlev Pektas. (2015) An Evaluation of the Protective Effects of Thymoquinone on Amikacin-Induced Ototoxicity in Rats. Clinical and Experimental Otorhinolaryngology 8:4, pages 312.
Crossref
Saeed Samarghandian, Mohsen Azimi-Nezhad, Hassan Mehrad-Majd & Seyed Reza Mirhafez. (2015) Thymoquinone Ameliorates Acute Renal Failure in Gentamicin-Treated Adult Male Rats. Pharmacology 96:3-4, pages 112-117.
Crossref
Mohd Ishtikhar, Gulam Rabbani, Shawez Khan & Rizwan Hasan Khan. (2015) Biophysical investigation of thymoquinone binding to ‘N’ and ‘B’ isoforms of human serum albumin: exploring the interaction mechanism and radical scavenging activity. RSC Advances 5:24, pages 18218-18232.
Crossref
F Aksoy, R Dogan, A Yenigun, B Veyseller, O Ozturan & B Ozturk. (2015) Thymoquinone treatment for inner-ear acoustic trauma in rats. The Journal of Laryngology & Otology 129:1, pages 38-45.
Crossref
İlker Öngüç Aycan, Orhan Tokgöz, Adnan Tüfek, Ulaş Alabalık, Osman Evliyaoğlu, Hüseyin Turgut, Feyzi Çelik & Abdulmenap Güzel. (2015) The use of thymoquinone in nephrotoxicity related to acetaminophen. International Journal of Surgery 13, pages 33-37.
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