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Research Article

Solubility and Stability of Lorazepam in Bile Salt/Soya Phosphatidylcholine–Mixed Micelles

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Pages 409-417 | Published online: 25 Mar 1999

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Read on this site (4)

Qin Guo, Jie Cai, Pengyu Li, Dongling Xu, Xiaomin Ni, Hui Wen, Dan Liu, Suizhen Lin & Haiyan Hu. (2016) Comparison of bile salt/phosphatidylcholine mixed micelles in solubilization to sterols and stability. Drug Design, Development and Therapy 10, pages 3789-3798.
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Fuxia Dong, Yunchang Xie, Jianping Qi, Fuqiang Hu, Yi Lu, Sanming Li & Wei Wu. (2013) Bile salt/phospholipid mixed micelle precursor pellets prepared by fluid-bed coating. International Journal of Nanomedicine 8, pages 1653-1663.
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Xu Song, Yu Jiang, Chunjuan Ren, Xun Sun, Qiang Zhang, Tao Gong & Zhirong Zhang. (2012) Nimodipine-loaded mixed micelles: formulation, compatibility, pharmacokinetics, and vascular irritability study. International Journal of Nanomedicine 7, pages 3689-3699.
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Gavin A. Magee, Jane French, Bob Gibbon & Chris Luscombe. (2003) Bile Salt/Lecithin Mixed Micelles Optimized for the Solubilization of a Poorly Soluble Steroid Molecule Using Statistical Experimental Design. Drug Development and Industrial Pharmacy 29:4, pages 441-450.
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Articles from other publishers (13)

Zahari Vinarov, Christophe Tistaert, Jan Bevernage, Hugo Bohets & Patrick Augustijns. (2024) Enzymatic prodrug degradation in the fasted and fed small intestine: In vitro studies and interindividual variability in human aspirates. International Journal of Pharmaceutics 649, pages 123654.
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Mariangeles Pérez de la Cruz-Moreno, Consuelo Montejo, Antonio Aguilar-Ros, Walthère Dewe, Benoît Beck, Jef Stappaerts, Jan Tack & Patrick Augustijns. (2017) Exploring drug solubility in fasted human intestinal fluid aspirates: Impact of inter-individual variability, sampling site and dilution. International Journal of Pharmaceutics 528:1-2, pages 471-484.
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Xiu Yu, Huan Xu, Meina Hu, Xiaojiao Luan, Kaiqian WangYuanshan Fu, Di Zhang & Jianying Li. (2015) Ginsenoside Rg3 Bile Salt-Phosphatidylcholine-Based Mixed Micelles: Design, Characterization, and Evaluation. CHEMICAL & PHARMACEUTICAL BULLETIN Chemical and Pharmaceutical Bulletin 63:5, pages 361-368.
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Masrat Maswal, Oyais Ahmad Chat, Suraya Jabeen, Uzma Ashraf, Rohi Masrat, Rais Ahmad Shah & Aijaz Ahmad Dar. (2015) Solubilization and co-solubilization of carbamazepine and nifedipine in mixed micellar systems: insights from surface tension, electronic absorption, fluorescence and HPLC measurements. RSC Advances 5:10, pages 7697-7712.
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Poonam Chopra, Jinsong Hao & S. Kevin Li. (2013) Influence of Drug Lipophilicity on Drug Release from Sclera After Iontophoretic Delivery of Mixed Micellar Carrier System to Human Sclera. Journal of Pharmaceutical Sciences 102:2, pages 480-488.
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Yanjun Zhao, Marc B. Brown, Rajeshree H. Khengar, Matthew J. Traynor, Pedro Barata & Stuart A. Jones. (2012) Pharmacokinetic Evaluation of Intranasally Administered Vinyl Polymer-Coated Lorazepam Microparticles in Rabbits. The AAPS Journal 14:2, pages 218-224.
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Jiang-nan Yu, Yuan Zhu, Li Wang, Min Peng, Shan-shan Tong, Xia Cao, Hui Qiu & Xi-ming Xu. (2010) Enhancement of oral bioavailability of the poorly water-soluble drug silybin by sodium cholate/phospholipid-mixed micelles. Acta Pharmacologica Sinica 31:6, pages 759-764.
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Hacer Cesur, Israel Rubinstein, Ashwini Pai & Hayat Önyüksel. (2009) Self-associated indisulam in phospholipid-based nanomicelles: a potential nanomedicine for cancer. Nanomedicine: Nanotechnology, Biology and Medicine 5:2, pages 178-183.
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Wei-Guo Dai, Liang C. Dong, Shu Li, Crystal Pollock-Dove, Jing Chen, Paul Mansky & Gary Eichenbaum. (2007) Parallel screening approach to identify solubility-enhancing formulations for improved bioavailability of a poorly water-soluble compound using milligram quantities of material. International Journal of Pharmaceutics 336:1, pages 1-11.
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MARINA EMIKO YAGIMA ODO, LUIZ CARLOS CUCÉ, LÍLIAN MAYUMI ODO & ANDRÉA NATRIELLI. (2007) Action of Sodium Deoxycholate on Subcutaneous Human Tissue: Local and Systemic Effects. Dermatologic Surgery 33:2, pages 178-189.
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MARINA EMIKO YAGIMA ODO, LUIZ CARLOS CUCÉ, LÍLIAN MAYUMI ODO & ANDRÉA NATRIELLI. (2007) Action of Sodium Deoxycholate on Subcutaneous Human Tissue. Dermatologic Surgery 33:2, pages 178-189.
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Timothy Scott Wiedmann & Lamya Kamel. (2002) Examination of the Solubilization of Drugs by Bile Salt Micelles. Journal of Pharmaceutical Sciences 91:8, pages 1743-1764.
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Patric Stenberg, Christel A.S. Bergstr??m, Kristina Luthman & Per Artursson. (2002) Theoretical Predictions of Drug Absorption in Drug Discovery and Development. Clinical Pharmacokinetics 41:11, pages 877-899.
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