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Research Article

Synthesis and Properties of Dextran–Nalidixic Acid Ester as a Colon-Specific Prodrug of Nalidixic Acid

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Pages 331-336 | Published online: 30 Apr 2001

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Siyao Liu, Zhongxiang Fang & Ken Ng. (2023) Recent development in fabrication and evaluation of phenolic-dietary fiber composites for potential treatment of colonic diseases. Critical Reviews in Food Science and Nutrition 63:24, pages 6860-6884.
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Joon Nam, Wooseong Kim, Sunyoung Lee, Seongkeun Jeong, Jin-Wook Yoo, Min-Soo Kim & Yunjin Jung. (2016) Dextran-5-(4-ethoxycarbonylphenylazo)salicylic acid ester, a polymeric colon-specific prodrug releasing 5-aminosalicylic acid and benzocaine, ameliorates TNBS-induced rat colitis. Journal of Drug Targeting 24:5, pages 468-474.
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Yonghyun Lee, In Ho Kim, Jeongyun Kim, Jeong-Hyun Yoon, Young Hee Shin, Yunjin Jung & Young Mi Kim. (2011) Evaluation of dextran-flufenamic acid ester as a polymeric colon-specific prodrug of flufenamic acid, an anti-inflammatory drug, for chronotherapy. Journal of Drug Targeting 19:5, pages 336-343.
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Fatemeh Ahmadi, Jaleh Varshosaz, Jaber Emami, Naser Tavakoli, Mohsen Minaiyan, Parvin Mahzouni & Farid Dorkoosh. (2011) Preparation and in vitro/in vivo evaluation of dextran matrix tablets of budesonide in experimental ulcerative colitis in rats. Drug Delivery 18:2, pages 122-130.
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Jaleh Varshosaz, Jaber Emami, Fatemeh Ahmadi, Naser Tavakoli, Mohsen Minaiyan, Afshin Fassihi, Parvin Mahzouni & Farid Dorkoosh. (2011) Preparation of budesonide–dextran conjugates using glutarate spacer as a colon-targeted drug delivery system: in vitro/in vivo evaluation in induced ulcerative colitis. Journal of Drug Targeting 19:2, pages 140-153.
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Jaleh Varshosaz, Fatemeh Ahmadi, Jaber Emami, Naser Tavakoli, Mohsen Minaiyan, Parvin Mahzouni & Farid Dorkoosh. (2011) Microencapsulation of budesonide with dextran by spray drying technique for colon-targeted delivery: an in vitro/in vivo evaluation in induced colitis in rat. Journal of Microencapsulation 28:1, pages 62-73.
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Yunjin Jung & Young Mi Kim. (2010) What should be considered on design of a colon-specific prodrug?. Expert Opinion on Drug Delivery 7:2, pages 245-258.
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A. J. Hao, Y. J. Deng, T. F. Li, X. B. Suo, Y. H. Cao, Y. L. Hao & Y. Zhang. (2006) Degradation Kinetics of Fluorouracil-Acetic-Acid-Dextran Conjugate in Aqueous Solution. Drug Development and Industrial Pharmacy 32:6, pages 757-763.
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M. K. Chourasia & S. K. Jain. (2004) Polysaccharides for Colon Targeted Drug Delivery. Drug Delivery 11:2, pages 129-148.
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Yukinori Yamauchi, Naoki Doi, Shin-ichi Kondo, Yasushi Sasai & Masayuki Kuzuya. (2020) Synthesis and Characterization of Polymer-Linked Prodrug of Antibacterial Agent for The Targeted Delivery to The Colon by Cold Plasma Technique. Journal of Photopolymer Science and Technology 33:3, pages 343-348.
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Magdalena Cristina Stanciu, Dalila Belei, Elena Bicu, Cristina G. Tuchilus & Marieta Nichifor. (2020) Novel amphiphilic dextran esters with antimicrobial activity. International Journal of Biological Macromolecules 150, pages 746-755.
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Shobhit Kumar, Javed Ali & Sanjula Baboota. 2019. Polysaccharide Carriers for Drug Delivery. Polysaccharide Carriers for Drug Delivery 443 475 .
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Hafezeh Nabipour, Moayad Hossaini Sadr & Nygil Thomas. (2016) Synthesis, controlled release and antibacterial studies of nalidixic acid–zinc hydroxide nitrate nanocomposites. New Journal of Chemistry 40:1, pages 238-244.
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Richard d'Arcy & Nicola Tirelli. (2014) Fishing for fire: strategies for biological targeting and criteria for material design in anti‐inflammatory therapies. Polymers for Advanced Technologies 25:5, pages 478-498.
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Mirela Nadler Milabuer, Yossi Kam & Abraham Rubinstein. 2010. Oral Controlled Release Formulation Design and Drug Delivery. Oral Controlled Release Formulation Design and Drug Delivery 225 243 .
João F. Pinto. (2010) Site-specific drug delivery systems within the gastro-intestinal tract: From the mouth to the colon. International Journal of Pharmaceutics 395:1-2, pages 44-52.
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P.K. Shrivastava, R. Singh & S.K. Shrivastava. (2010) Dextran successful carrier molecule for the delivery of NSAIDs with reduced gastrointestinal effect. Journal of Drug Delivery Science and Technology 20:2, pages 135-142.
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A. Rasheed & C. K. A. Kumar. (2009) Novel approaches on prodrug based drug design. Pharmaceutical Chemistry Journal 42:12, pages 677-686.
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Steven Neau. 2008. Water-Insoluble Drug Formulation, Second Edition. Water-Insoluble Drug Formulation, Second Edition 437 466 .
R. PAWAR, W. JADHAV, S. BHUSARE, R. BORADE, S. FARBER, D. ITZKOWITZ & A. DOMB. 2008. Natural-Based Polymers for Biomedical Applications. Natural-Based Polymers for Biomedical Applications 3 53 .
V.R Sinha & Rachna Kumria. (2003) Microbially triggered drug delivery to the colon. European Journal of Pharmaceutical Sciences 18:1, pages 3-18.
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