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Drug Development and Industrial Pharmacy Volume 28, 2002 - Issue 2
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Research Article

Controlled-Release Naproxen Using Micronized Ethyl Cellulose by Wet-Granulation and Solid-Dispersion Method

Zabed Iqbal Wyeth Ayerst Pharmaceuticals, 401 N. Middletown Road, Pearl RiverNY, 10965, U.S.A.
,
Almas Babar Long Island University, Brooklyn, NY, 11201, U.S.A.
&
Muhammad Ashraf Wyeth Ayerst Research, Pearl RiverNY, 10965, U.S.A.
Pages 129-134 | Published online: 04 Aug 2002

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Seçil Kaya & Ebru Kondolot Solak. (2023) Development of ketorolac tromethamine loaded biocompatible polymeric microspheres and matrix films: designing for topical application. International Journal of Polymeric Materials and Polymeric Biomaterials 72:17, pages 1329-1339.
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Min Soo Kim, Dong Woo Yeom, Sung Rae Kim, Ho Yub Yoon, Chang Hyun Kim, Ho Yong Son, Jin Han Kim, Sangkil Lee & Young Wook Choi. (2017) Development of a chitosan based double layer-coated tablet as a platform for colon-specific drug delivery. Drug Design, Development and Therapy 11, pages 45-57.
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Abdolrahim Abbaszad Rafi & Mehrdad Mahkam. (2015) Preparation of Magnetic pH-Sensitive Film With Alginate Base for Colon Specific Drug Delivery. International Journal of Polymeric Materials and Polymeric Biomaterials 64:4, pages 214-219.
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Yanzhu Wang, Lizhang Sun, Tongying Jiang, Jinghai Zhang, Chen Zhang, Changshan Sun, Yihui Deng, Jin Sun & Siling Wang. (2014) The investigation of MCM-48-type and MCM-41-type mesoporous silica as oral solid dispersion carriers for water insoluble cilostazol. Drug Development and Industrial Pharmacy 40:6, pages 819-828.
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Shivaan Cooppan, Yahya E. Choonara, Lisa C. du Toit, Valence M. K. Ndesendo, Pradeep Kumar & Viness Pillay. (2013) A novel pH-dependant and double crosslinked polymethacrylate-based polysphere matrix for enteric delivery of isoniazid. Pharmaceutical Development and Technology 18:5, pages 1066-1077.
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Tazin Mahnaj, Salah U. Ahmed & Fotios M. Plakogiannis. (2013) Characterization of ethyl cellulose polymer. Pharmaceutical Development and Technology 18:5, pages 982-989.
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Hailong Li, Xin-Sheng Chai, Huaiyu Zhan, Mengru Liu & Shiyu Fu. (2012) A Novel Method for Determination of Ethoxyl Content in Ethyl Cellulose by Headspace Gas Chromatography. Analytical Letters 45:9, pages 1028-1035.
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Articles from other publishers (29)

Niuosha Sanaeifar, Karsten Mäder & Dariush Hinderberger. (2022) Macro- and Nanoscale Effect of Ethanol on Bovine Serum Albumin Gelation and Naproxen Release. International Journal of Molecular Sciences 23:13, pages 7352.
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PRASENJIT SARKAR, SAUMYAJYOTI DAS & SUTAPA BISWAS MAJEE. (2022) SOLID DISPERSION TABLETS IN IMPROVING ORAL BIOAVAILABILITY OF POORLY SOLUBLE DRUGS. International Journal of Current Pharmaceutical Research, pages 15-20.
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Ritu Kaushik, Vikas Budhwar & Deepak Kaushik. (2020) An Overview on Recent Patents and Technologies on Solid Dispersion. Recent Patents on Drug Delivery & Formulation 14:1, pages 63-74.
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Amr Zaitoon & Loong-Tak Lim. (2020) Effect of poly(ethylene oxide) on the electrospinning behavior and characteristics of ethyl cellulose composite fibers. Materialia 10, pages 100649.
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Ahmed Elkhabaz, Sreya Sarkar, Garth J. Simpson & Lynne S. Taylor. (2019) Characterization of Phase Transformations for Amorphous Solid Dispersions of a Weakly Basic Drug upon Dissolution in Biorelevant Media. Pharmaceutical Research 36:12.
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Bin Bin Huang, Dong Xu Liu, De Kun Liu & Gang Wu. (2019) Application of Solid Dispersion Technique to Improve Solubility and Sustain Release of Emamectin Benzoate. Molecules 24:23, pages 4315.
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Na Li & Lynne S. Taylor. (2018) Tailoring supersaturation from amorphous solid dispersions. Journal of Controlled Release 279, pages 114-125.
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Apratim Jash & Loong-Tak Lim. (2017) Triggered release of hexanal from an imidazolidine precursor encapsulated in poly(lactic acid) and ethylcellulose carriers. Journal of Materials Science 53:3, pages 2221-2235.
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Zhu Zhang, Wenbing Li, Guanghua Wang, Yang-Lu Qu & Deng-Guang Yu. (2018) Electrospun 4th-Generation Solid Dispersions of Poorly Water-Soluble Drug Utilizing Two Different Processes. Journal of Nanomaterials 2018, pages 1-10.
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Abdolrahim Abbaszad Rafi, Fariba Fakheri & Mehrdad Mahkam. (2016) Synthesis and preparation of new pH-sensitive nanocomposite and nanocapsule based on “MCM-41/poly methacrylic acid” as drug carriers. Polymer Bulletin 73:10, pages 2649-2659.
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Pratchaya TipduangtaPeter BeltonLászló FábiánLi Ying Wang, Huiru Tang, Mark EddlestonSheng Qi. (2015) Electrospun Polymer Blend Nanofibers for Tunable Drug Delivery: The Role of Transformative Phase Separation on Controlling the Release Rate. Molecular Pharmaceutics 13:1, pages 25-39.
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Dong-Wook Kim & Jun-Bom Park. (2015) Development and pharmaceutical approach for sustained-released metformin succinate tablets. Journal of Drug Delivery Science and Technology 30, pages 90-99.
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Dinesh Kumar Mishra, Vinod Dhote, Arpit Bhargava, Dinesh Kumar Jain & Pradyumna Kumar Mishra. (2015) Amorphous solid dispersion technique for improved drug delivery: basics to clinical applications. Drug Delivery and Translational Research 5:6, pages 552-565.
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Rama Mallipeddi, Kalyan K. Saripella & Steven H. Neau. (2014) Use of fine particle ethylcellulose as the diluent in the production of pellets by extrusion-spheronization. Saudi Pharmaceutical Journal 22:4, pages 360-372.
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Chau Le-Ngoc Vo, Chulhun Park & Beom-Jin Lee. (2013) Current trends and future perspectives of solid dispersions containing poorly water-soluble drugs. European Journal of Pharmaceutics and Biopharmaceutics 85:3, pages 799-813.
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Tapan Kumar Giri, Kulesh Kumar, Amit Alexander, Ajazuddin, Hemant Badwaik & Dulal Krishna Tripathi. (2012) A novel and alternative approach to controlled release drug delivery system based on solid dispersion technique. Bulletin of Faculty of Pharmacy, Cairo University 50:2, pages 147-159.
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Ja Won Kim, Min Jeong Song, Sang Min Lee, So Ryong Lim, Su Jin Jung & Hong Sung Kim. (2012) Drug-release Properties of Double-layered Microspherical Carriers which Consist of Outer Shell of Poly(D,L-lactide) and Inner Core of Alginate or Chitosan. Polymer Korea 36:6, pages 699-704.
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Pinaki Ghosh, Kiran S. Bhise, Anant R. Paradkar, S. L. Bodhankar & Shivajirao S. Kadam. (2012) Reduced Ulcerogenic Potential and Antiarthritic Effect of Chitosan–Naproxen Sodium Complexes. AAPS PharmSciTech 13:3, pages 896-902.
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Shuxin Wan, Yingqian Sun, Xiuxiang Qi & Fengping Tan. (2011) Improved Bioavailability of Poorly Water-Soluble Drug Curcumin in Cellulose Acetate Solid Dispersion. AAPS PharmSciTech 13:1, pages 159-166.
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Phuong Ha-Lien Tran, Thao Truong-Dinh Tran, Jun Bom Park & Beom-Jin Lee. (2011) Controlled Release Systems Containing Solid Dispersions: Strategies and Mechanisms. Pharmaceutical Research 28:10, pages 2353-2378.
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Farhad Tajarobi, Anette Larsson, Hanna Matic & Susanna Abrahmsén-Alami. (2011) The influence of crystallization inhibition of HPMC and HPMCAS on model substance dissolution and release in swellable matrix tablets. European Journal of Pharmaceutics and Biopharmaceutics 78:1, pages 125-133.
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Kiran S. Bhise, Ravindra S. Dhumal, Biradar Shailesh, Anant R. Paradkar & Shivajirao S. Kadam. (2010) Effect of Oppositely Charged Polymer and Dissolution Media on Rheology of Spray-Dried Ionic Complexes. AAPS PharmSciTech 11:1, pages 226-232.
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Stuart Cantor & Armin Gerhardt. 2008. Pharmaceutical Dosage Forms - Tablets. Pharmaceutical Dosage Forms - Tablets 261 301 .
Stuart Cantor, Larry Augsburger & Armin Gerhardt. 2008. Pharmaceutical Dosage Forms - Tablets, Third Edition. Pharmaceutical Dosage Forms - Tablets, Third Edition 261 301 .
Punna Rao Ravi, Udaya Kanth Kotreka & Ranendra Narayan Saha. (2008) Controlled Release Matrix Tablets of Zidovudine: Effect of Formulation Variables on the In Vitro Drug Release Kinetics. AAPS PharmSciTech 9:1, pages 302-313.
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Kiran S. Bhise, Ravindra S. Dhumal, Anant R. Paradkar & Shivajirao S Kadam. (2007) Effect of Drying Methods on Swelling, Erosion and Drug Release from Chitosan–Naproxen Sodium Complexes. AAPS PharmSciTech 9:1, pages 1-12.
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Kiran S. Bhise, Ravindra S. Dhumal, Bhaskar Chauhan, Anant Paradkar & Shivajirao S. Kadam. (2007) Effect of oppositely charged polymer and dissolution medium on swelling, erosion, and drug release from chitosan matrices. AAPS PharmSciTech 8:2, pages E110-E118.
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Muhammad Khan Sarfr, Nisar -ur-Rehman, Saeed Ahmed, Mohammad Ashraf & Sabeeh Mohsin. (2007) Ethyl Cellulose-Based Solid Matrix System for Sustaining Release of Naproxen. Pakistan Journal of Biological Sciences 10:4, pages 668-672.
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J. Desai, K. Alexander & A. Riga. (2006) Characterization of polymeric dispersions of dimenhydrinate in ethyl cellulose for controlled release. International Journal of Pharmaceutics 308:1-2, pages 115-123.
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