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Drug Development and Industrial Pharmacy Volume 30, 2004 - Issue 5
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Research Article

pH Dependent Uptake of Loperamide Across the Gastrointestinal Tract: An In Vitro Study

Andrew Crowe School of Pharmacy, Curtin University of Technology, GPO Box U1987, Perth, Western Australia, 6845
&
Penny Wong School of Pharmacy, Curtin University of Technology, GPO Box U1987, Perth, Western Australia, 6845
Pages 449-459 | Published online: 25 May 2004

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Read on this site (2)

Donna A. Volpe, Abhay Joshi & Vikram Arya. (2022) Do differences in cell lines and methods used for calculation of IC50 values influence categorisation of drugs as P-glycoprotein substrates and inhibitors?. Xenobiotica 52:7, pages 751-757.
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Justin P. Reinert & Rebecca L. Dunn. (2019) Management of overdoses of loperamide, gabapentin, and modafinil: a literature review. Expert Review of Clinical Pharmacology 12:9, pages 901-908.
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Articles from other publishers (9)

Angela Effinger, Caitriona M O'Driscoll, Mark McAllister & Nikoletta Fotaki. (2020) Gastrointestinal diseases and their impact on drug solubility: Crohn's disease. European Journal of Pharmaceutical Sciences 152, pages 105459.
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S M D K Ganga Senarathna, Madhu Page-Sharp & Andrew Crowe. (2016) The Interactions of P-Glycoprotein with Antimalarial Drugs, Including Substrate Affinity, Inhibition and Regulation. PLOS ONE 11:4, pages e0152677.
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Susan E. Pratt, Sara Durland-Busbice, Robert L. Shepard, Kathleen Heinz-Taheny, Philip W. Iversen & Anne H. Dantzig. (2013) Human Carboxylesterase-2 Hydrolyzes the Prodrug of Gemcitabine (LY2334737) and Confers Prodrug Sensitivity to Cancer Cells. Clinical Cancer Research 19:5, pages 1159-1168.
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Miriam S. Rubelt, Salah Amasheh, Thomas Grobosch & Christoph Stein. (2012) Liquid Chromatography-Tandem Mass Spectrometry for Analysis of Intestinal Permeability of Loperamide in Physiological Buffer. PLoS ONE 7:11, pages e48502.
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Mouna Kanaan, Youssef Daali, Pierre Dayer & Jules Desmeules. (2009) Uptake/Efflux Transport of Tramadol Enantiomers and O -Desmethyl-Tramadol: Focus on P -Glycoprotein . Basic & Clinical Pharmacology & Toxicology 105:3, pages 199-206.
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Andrew Crowe & Susanna Diep. (2008) pH dependent efflux of methamphetamine derivatives and their reversal through human Caco-2 cell monolayers. European Journal of Pharmacology 592:1-3, pages 7-12.
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Grégori Gerebtzoff & Anna Seelig. (2006) In Silico Prediction of Blood−Brain Barrier Permeation Using the Calculated Molecular Cross-Sectional Area as Main Parameter. Journal of Chemical Information and Modeling 46:6, pages 2638-2650.
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Andrew Crowe, Kenneth F. Ilett, Harin A. Karunajeewa, Kevin T. Batty & Timothy M. E. Davis. (2006) Role of P Glycoprotein in Absorption of Novel Antimalarial Drugs. Antimicrobial Agents and Chemotherapy 50:10, pages 3504-3506.
Crossref
Sarfaraz Niazi. 2006. Handbook of Preformulation. Handbook of Preformulation 1 32 .

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