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Research Article

INHIBITION OF CARCINOGENESIS BY ISOTHIOCYANATES*

Pages 395-411 | Published online: 10 Oct 2000

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Silvia D. Stan, Shivendra V. Singh, David C. Whitcomb & Randall E. Brand. (2014) Phenethyl Isothiocyanate Inhibits Proliferation and Induces Apoptosis in Pancreatic Cancer Cells In Vitro and in a MIAPaca2 Xenograft Animal Model. Nutrition and Cancer 66:4, pages 747-755.
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Anna Minarini, Andrea Milelli, Carmela Fimognari, Elena Simoni, Eleonora Turrini & Vincenzo Tumiatti. (2014) Exploring the effects of isothiocyanates on chemotherapeutic drugs. Expert Opinion on Drug Metabolism & Toxicology 10:1, pages 25-38.
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D. Kalpana Deepa Priya, R. Gayathri, G. R. Gunassekaran, S. Murugan & D. Sakthisekaran. (2013) Apoptotic role of natural isothiocyanate from broccoli (Brassica oleracea italica) in experimental chemical lung carcinogenesis. Pharmaceutical Biology 51:5, pages 621-628.
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Kozue Sakao, Eun-Ryeong Hahm & ShivendraV. Singh. (2013) In Vitro and In Vivo Effects of Phenethyl Isothiocyanate Treatment on Vimentin Protein Expression in Cancer Cells. Nutrition and Cancer 65:sup1, pages 61-67.
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Natalya Hanlon, Nattaya Konsue, Nick Coldham, MauriceJ. Sauer & Costas Ioannides. (2011) Exposure to Isothiocyanates Suppresses Urinary Mutagenicity in Rats Treated With Heterocyclic Amine IQ: Lack of Association With CYP1 Activity. Nutrition and Cancer 63:2, pages 300-305.
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Anoop Kumar, Paolo Vineis, Carlotta Sacerdote, Laura Fiorini & Gabriele Sabbioni. (2010) Determination of new biomarkers to monitor the dietary consumption of isothiocyanates. Biomarkers 15:8, pages 739-745.
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Yoshimasa NAKAMURA & Noriyuki MIYOSHI. (2010) Electrophiles in Foods: The Current Status of Isothiocyanates and Their Chemical Biology. Bioscience, Biotechnology, and Biochemistry 74:2, pages 242-255.
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SagarA. Mayekar, AtulC. Chaskar & VinataV. Mulwad. (2009) Facile Synthesis of Coumarinyl Isothiocyanate from Amino Coumarin. Synthetic Communications 40:1, pages 46-51.
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Chengguo Xing, Thomas E. Johnson & Paul J. Limburg. (2008) Diets, Phytochemicals, and Chemoprevention of Tumorigenesis. Journal of Dietary Supplements 5:2, pages 95-105.
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Graham R Jang & Robert Z Harris. (2007) Drug interactions involving ethanol and alcoholic beverages. Expert Opinion on Drug Metabolism & Toxicology 3:5, pages 719-731.
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CynthiaA. Thomson, CherylL. Rock, BetteJ. Caan, ShirleyW. Flatt, WaelA. Al-Delaimy, VickyA. Newman, RichardA. Hajek, JaniceA. Chilton & JohnP. Pierce. (2007) Increase in Cruciferous Vegetable Intake in Women Previously Treated for Breast Cancer Participating in a Dietary Intervention Trial. Nutrition and Cancer 57:1, pages 11-19.
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Rex Munday, Yuesheng Zhang, Jed W. Fahey, Hillary E. Jobson, Christine M. Munday, Jun Li & Katherine K. Stephenson. (2006) Evaluation of Isothiocyanates as Potent Inducers of Carcinogen-Detoxifying Enzymes in the Urinary Bladder: Critical Nature of In Vivo Bioassay. Nutrition and Cancer 54:2, pages 223-231.
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Chantey R. Morris, Sheng C. Chen, Lin Zhou, Lawrence M. Schopfer, Xinxin Ding & Sidney S. Mirvish. (2004) Inhibition by Allyl Sulfides and Phenethyl Isothiocyanate of Methyl-n-pentylnitrosamine Depentylation by Rat Esophageal Microsomes, Human and Rat CYP2E1, and Rat CYP2A3. Nutrition and Cancer 48:1, pages 54-63.
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Franca Bianchini & Harri Vainio. (2004) Isothiocyanates in Cancer Prevention. Drug Metabolism Reviews 36:3-4, pages 655-667.
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RajeshwarP. Verma. (2003) Synthesis and Reactions of 1,1-Dimethyl-3-oxobutyl-isothiocyanate (DMO-ITC). Phosphorus, Sulfur, and Silicon and the Related Elements 178:2, pages 365-416.
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Theresa J Smith. (2001) Mechanisms of carcinogenesis inhibition by isothiocyanates. Expert Opinion on Investigational Drugs 10:12, pages 2167-2174.
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