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Drug Metabolism Reviews Volume 34, 2002 - Issue 4
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Research Article

PREDICTING PHARMACOKINETICS AND DRUG INTERACTIONS IN PATIENTS FROM IN VITRO AND IN VIVO MODELS: THE EXPERIENCE WITH 5,6-DIMETHYLXANTHENONE-4-ACETIC ACID (DMXAA), AN ANTI-CANCER DRUG ELIMINATED MAINLY BY CONJUGATION

Shufeng Zhou Division of Pharmacology and Clinical Pharmacology, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand
,
Philip Kestell Auckland Cancer Society Research Center, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand
&
James W. Paxton Division of Pharmacology and Clinical Pharmacology, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand
Pages 751-790 | Published online: 27 Nov 2002

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Shu-Feng Zhou, Bo Wang, Li-Ping Yang & Jun-Ping Liu. (2010) Structure, function, regulation and polymorphism and the clinical significance of human cytochrome P450 1A2. Drug Metabolism Reviews 42:2, pages 268-354.
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Shu-Feng Zhou, Jun-Ping Liu & Balram Chowbay. (2009) Polymorphism of human cytochrome P450 enzymes and its clinical impact. Drug Metabolism Reviews 41:2, pages 89-295.
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Lanhai Lü, Maria S. M. Wai, David T. Yew & Ying T. Mak. (2009) Pien Tze Huang, a Composite Chinese Traditional Herbal Extract, Affects Survival of Neuroblastoma Cells. International Journal of Neuroscience 119:2, pages 255-262.
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Articles from other publishers (9)

Subhasree Nag, Jiang-Jiang Qin, Sukesh Voruganti, Ming-Hai Wang, Horrick Sharma, Shivaputra Patil, John K. Buolamwini, Wei Wang & Ruiwen Zhang. (2015) Development and validation of a rapid HPLC method for quantitation of SP-141, a novel pyrido[b]indole anticancer agent, and an initial pharmacokinetic study in mice. Biomedical Chromatography 29:5, pages 654-663.
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Haibo Li, Scharri J. Ezell, Xiangrong Zhang, Wei Wang, Hongxia Xu, Elizabeth R. Rayburn, Xu Zhang, Evrim Gurpinar, Xinyi Yang, Charnell I. Sommers, Sadanandan E. Velu & Ruiwen Zhang. (2011) Development and validation of an HPLC method for quantitation of BA-TPQ, a novel iminoquinone anticancer agent, and an initial pharmacokinetic study in mice. Biomedical Chromatography 25:5, pages 628-634.
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. 2010. Mixture Toxicity. Mixture Toxicity 229 269 .
Lanhai Lü, Ying T. Mak, Marong Fang & David T. Yew. (2009) The difference in gliosis induced by β-amyloid and Tau treatments in astrocyte cultures derived from senescence accelerated and normal mouse strains. Biogerontology 10:6, pages 695-710.
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M. B. Jameson, B. C. Baguley, P. Kestell, L. Zhao, J. W. Paxton, P. I. Thompson & S. Waller. (2006) Pharmacokinetics of 5,6-dimethylxanthenone-4-acetic acid (AS1404), a novel vascular disrupting agent, in phase I clinical trial. Cancer Chemotherapy and Pharmacology 59:5, pages 681-687.
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Xiao-Xia Yang, Ze-Ping Hu, Sui Yung Chan & Shu-Feng Zhou. (2006) Monitoring drug–protein interaction. Clinica Chimica Acta 365:1-2, pages 9-29.
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Hidefumi Kaji & Toshiyuki Kume. (2005) Glucuronidation of 2-(4-Chlorophenyl)-5-(2-Furyl)-4-Oxazoleacetic Acid (TA-1801A) in Humans: Species Differences in Liver and Intestinal Microsomes. Drug Metabolism and Pharmacokinetics 20:3, pages 206-211.
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Shufeng Zhou, Xia Feng, Philip Kestell, Bruce C. Baguley & James W. Paxton. (2004) Determination of the investigational anti-cancer drug 5,6-dimethylxanthenone-4-acetic acid and its acyl glucuronide in Caco-2 monolayers by liquid chromatography with fluorescence detection: application to transport studies. Journal of Chromatography B 809:1, pages 87-97.
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Gary W. Caldwell, Zhengyin Yan, John A. Masucci, William Hageman, Gregory Leo & David M. Ritchie. (2012) Applied Pharmacokinetics in Drug Development. Pharmaceutical Development and Regulation 1:2, pages 117-132.
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