Drug Metabolism Reviews, Volume 34, Issue 4 (2002)

Browse this journal
Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days

Drug Metabolism Reviews, Volume 34, Issue 4 (2002)

See all volumes and issues
Vol 56, 2024 Vol 55, 2023 Vol 54, 2022 Vol 53, 2021 Vol 52, 2020 Vol 51, 2019 Vol 50, 2018 Vol 49, 2017 Vol 48, 2016 Vol 47, 2015 Vol 46, 2014 Vol 45, 2013-2014 Vol 44, 2012 Vol 43, 2011 Vol 42, 2010 Vol 41, 2009 Vol 40, 2008 Vol 39, 2007 Vol 38, 2006 Vol 37, 2005 Vol 36, 2004 Vol 35, 2003 Volume 34, 2002 Vol 33, 2001 Vol 32, 2000 Vol 31, 1999 Vol 30, 1998 Vol 29, 1997 Vol 28, 1996 Vol 27, 1995 Vol 26, 1994 Vol 25, 1993 Vol 24, 1992 Vol 23, 1991 Vol 22, 1990 Vol 21, 1989 Vol 20, 1989 Vol 19, 1988 Vol 18, 1987 Vol 17, 1986 Vol 16, 1985 Vol 15, 1984 Vol 14, 1983 Vol 13, 1982 Vol 12, 1981 Vol 11, 1980 Vol 10, 1979 Vol 9, 1979 Vol 8, 1978 Vol 7, 1978 Vol 6, 1977 Vol 5, 1976 Vol 4, 1975 Vol 3, 1975 Vol 2, 1974 Vol 1, 1972
Download citations Download PDFs Download issue

Research Article

Article
IN VITRO STUDIES IN DRUG DISCOVERY AND DEVELOPMENT: AN ANALYSIS OF STUDY OBJECTIVES AND APPLICATION OF GOOD LABORATORY PRACTICES (GLP)
Manoj Bajpai & Joel D. Esmay
Pages: 679-689
Published online: 27 Nov 2002
AbstractforIN VITRO STUDIES IN DRUG DISCOVERY AND DEVELOPMENT: AN ANALYSIS OF STUDY OBJECTIVES AND APPLICATION OF GOOD LABORATORY PRACTICES (GLP) | Full Text | References | PDF (115.2 KB)
  • 710 Views
  • 11 CrossRef citations
  • 0Altmetric
Article
MECHANISTIC ENZYMOLOGY OF OXYGEN ACTIVATION BY THE CYTOCHROMES P450
Thomas M. Makris, Roman Davydov, Ilia G. Denisov, Brian M. Hoffman & Stephen G. Sligar
Pages: 691-708
Published online: 27 Nov 2002
AbstractforMECHANISTIC ENZYMOLOGY OF OXYGEN ACTIVATION BY THE CYTOCHROMES P450 | Full Text | References | PDF (197.7 KB)
  • 318 Views
  • 61 CrossRef citations
  • 0Altmetric
Article
STRUCTURAL BIOLOGY AND FUNCTION OF SOLUTE TRANSPORTERS: IMPLICATIONS FOR IDENTIFYING AND DESIGNING SUBSTRATES
Eric Y. Zhang, Gregory T. Knipp, Sean Ekins & Peter W. Swaan
Pages: 709-750
Published online: 27 Nov 2002
AbstractforSTRUCTURAL BIOLOGY AND FUNCTION OF SOLUTE TRANSPORTERS: IMPLICATIONS FOR IDENTIFYING AND DESIGNING SUBSTRATES | Full Text | References | PDF (495 KB)
  • 368 Views
  • 53 CrossRef citations
  • 0Altmetric
Article
PREDICTING PHARMACOKINETICS AND DRUG INTERACTIONS IN PATIENTS FROM IN VITRO AND IN VIVO MODELS: THE EXPERIENCE WITH 5,6-DIMETHYLXANTHENONE-4-ACETIC ACID (DMXAA), AN ANTI-CANCER DRUG ELIMINATED MAINLY BY CONJUGATION
Shufeng Zhou, Philip Kestell & James W. Paxton
Pages: 751-790
Published online: 27 Nov 2002
AbstractforPREDICTING PHARMACOKINETICS AND DRUG INTERACTIONS IN PATIENTS FROM IN VITRO AND IN VIVO MODELS: THE EXPERIENCE WITH 5,6-DIMETHYLXANTHENONE-4-ACETIC ACID (DMXAA), AN ANTI-CANCER DRUG ELIMINATED MAINLY BY CONJUGATION | Full Text | References | PDF (365.5 KB)
  • 257 Views
  • 12 CrossRef citations
  • 0Altmetric
Article
NAPHTHALENE-INDUCED RESPIRATORY TRACT TOXICITY: METABOLIC MECHANISMS OF TOXICITY
A. Buckpitt, B. Boland, M. Isbell, D. Morin, M. Shultz, R. Baldwin, K. Chan, A. Karlsson, C. Lin, A. Taff, J. West, M. Fanucchi, L. Van Winkle & C. Plopper
Pages: 791-820
Published online: 27 Nov 2002
AbstractforNAPHTHALENE-INDUCED RESPIRATORY TRACT TOXICITY: METABOLIC MECHANISMS OF TOXICITY | Full Text | References | PDF (278.7 KB)
  • 1061 Views
  • 108 CrossRef citations
  • 0Altmetric
Article
GLUTATHIONE CONJUGATES AND THEIR SYNTHETIC DERIVATIVES AS INHIBITORS OF GLUTATHIONE-DEPENDENT ENZYMES INVOLVED IN CANCER AND DRUG RESISTANCE
Danny Burg & Gerard J. Mulder
Pages: 821-863
Published online: 27 Nov 2002
AbstractforGLUTATHIONE CONJUGATES AND THEIR SYNTHETIC DERIVATIVES AS INHIBITORS OF GLUTATHIONE-DEPENDENT ENZYMES INVOLVED IN CANCER AND DRUG RESISTANCE | Full Text | References | PDF (499.6 KB)
  • 252 Views
  • 55 CrossRef citations
  • 0Altmetric
Article
INTERINDIVIDUAL DIFFERENCES IN NICOTINE METABOLISM AND GENETIC POLYMORPHISMS OF HUMAN CYP2A6
Miki Nakajima, Yukio Kuroiwa & Tsuyoshi Yokoi
Pages: 865-877
Published online: 27 Nov 2002
AbstractforINTERINDIVIDUAL DIFFERENCES IN NICOTINE METABOLISM AND GENETIC POLYMORPHISMS OF HUMAN CYP2A6 | Full Text | References | PDF (203.6 KB)
  • 335 Views
  • 52 CrossRef citations
  • 0Altmetric

Explore articles

Explore the most recently published articles

Enzyme-mediated drug-drug interactions: a review of in vivo and in vitro methodologies, regulatory guidance, and translation to the clinic
Jaydeep Yadav et al.
Review Article | Published online: 26 Jul 2024
Bioactivation and reactivity research advances – 2023 year in review
Shuai Wang et al.
Review Article | Published online: 17 Jul 2024
Biotransformation research advances – 2023 year in review
S. Cyrus Khojasteh et al.
Review Article | Published online: 11 Jul 2024
Transporter-mediated drug-drug interactions: regulatory guidelines, in vitro and in vivo methodologies and translation, special populations, and the blood-brain barrier
Laura E. Russell et al.
Review Article | Published online: 5 Jul 2024
View all latest articles