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Wojciech Kuban & Władysława Anna Daniel. (2021) Cytochrome P450 expression and regulation in the brain. Drug Metabolism Reviews 53:1, pages 1-29.
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Surya Narayan Rath, Lingaraja Jena & Manorama Patri. (2020) Understanding ligands driven mechanism of wild and mutant aryl hydrocarbon receptor in presence of phytochemicals combating Parkinson’s disease: an in silico and in vivo study. Journal of Biomolecular Structure and Dynamics 38:3, pages 807-826.
Read now
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Anna Haduch & Władysława Anna Daniel. (2018) The engagement of brain cytochrome P450 in the metabolism of endogenous neuroactive substrates: a possible role in mental disorders. Drug Metabolism Reviews 50:4, pages 415-429.
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Ying Mu, Sunitha Kodidela, Yujie Wang, Santosh Kumar & Theodore J. Cory. (2018) The dawn of precision medicine in HIV: state of the art of pharmacotherapy. Expert Opinion on Pharmacotherapy 19:14, pages 1581-1595.
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Poonam Giri, Prashant Delvadia, Laxmikant Gupta, Nirmal Patel, Priyal Trivedi, Krishna Lad, Hiren M. Patel & Nuggehally R. Srinivas. (2018) Consequences of daily corticosteroid dosing with or without pre-treatment with quinidine on the in vivo cytochrome P450 2D (CYP2D) enzyme in rats: effect on O-demethylation activity of dextromethorphan and expression levels of CYP2D1 mRNA. Xenobiotica 48:1, pages 1-10.
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Francesca Toselli, Peter R. Dodd & Elizabeth M. J. Gillam. (2016) Emerging roles for brain drug-metabolizing cytochrome P450 enzymes in neuropsychiatric conditions and responses to drugs. Drug Metabolism Reviews 48:3, pages 379-404.
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Stefano Porcelli, Chiara Fabbri, Edoardo Spina, Alessandro Serretti & Diana De Ronchi. (2011) Genetic polymorphisms of cytochrome P450 enzymes and antidepressant metabolism. Expert Opinion on Drug Metabolism & Toxicology 7:9, pages 1101-1115.
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Fabien Dutheil, Aude Jacob, Sandrine Dauchy, Philippe Beaune, Jean-Michel Scherrmann, Xavier Declèves & Marie-Anne Loriot. (2010) ABC transporters and cytochromes P450 in the human central nervous system: influence on brain pharmacokinetics and contribution to neurodegenerative disorders. Expert Opinion on Drug Metabolism & Toxicology 6:10, pages 1161-1174.
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Sunao Kaneko, Shuichi Yoshida, Kazuaki Kanai, Norio Yasui-Furukori & Hiroto Iwasa. (2008) Development of individualized medicine for epilepsy based on genetic information. Expert Review of Clinical Pharmacology 1:5, pages 661-681.
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C. Woodland, T. T. Huang, E. Gryz, R. Bendayan & J. P. Fawcett. (2008) Expression, Activity and Regulation of CYP3A in Human and Rodent Brain. Drug Metabolism Reviews 40:1, pages 149-168.
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Articles from other publishers (96)
Yuanyuan Zhang, Chun Zhou, Sisi Yang, Yanjun Zhang, Ziliang Ye, Panpan He, Mengyi Liu, Qimeng Wu & Xianhui Qin. (2023) Association of regular use of ibuprofen and paracetamol, genetic susceptibility, and new-onset dementia in the older population. General Hospital Psychiatry 84, pages 226-233.
Crossref
Crossref
Ann F. Hubbs, Dale W. Porter, Robert R. Mercer, Vincent Castranova, Linda M. Sargent & Krishnan Sriram. 2023. Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 3. Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 3
797
838
.
Roshni Das, Gianna Ragagnin, Jessica Sjöstedt, Maja Johansson, David Haage, Michael Druzin, Staffan Johansson & Torbjörn Bäckström. (2022) Medroxyprogesterone acetate positively modulates specific GABAA-receptor subtypes - affecting memory and cognition. Psychoneuroendocrinology 141, pages 105754.
Crossref
Crossref
Marlaina R. Stocco & Rachel F. Tyndale. 2022. Pharmacology and Toxicology of Cytochrome P450 – 60th Anniversary. Pharmacology and Toxicology of Cytochrome P450 – 60th Anniversary
73
106
.
Muhammad Imran Khan, Inzemam Khan, Saeed Ahmad Khan & Waqas Nawaz. 2022. Biochemistry of Drug Metabolizing Enzymes. Biochemistry of Drug Metabolizing Enzymes
259
280
.
Mariamena Arbitrio, Francesca Scionti, Maria Teresa Di Martino, Licia Pensabene, Pierfrancesco Tassone & Pierosandro Tagliaferri. 2022. Comprehensive Pharmacology. Comprehensive Pharmacology
657
697
.
Ewa Niedzielska-Andres, Bartłomiej Rospond, Lucyna Pomierny-Chamioło, Anna Sadakierska-Chudy & Małgorzata Filip. 2022. Handbook of Neurotoxicity. Handbook of Neurotoxicity
3
19
.
Przemysław J. Danek & Władysława A. Daniel. (2021) Long-Term Treatment with Atypical Antipsychotic Iloperidone Modulates Cytochrome P450 2D (CYP2D) Expression and Activity in the Liver and Brain via Different Mechanisms. Cells 10:12, pages 3472.
Crossref
Crossref
Daniela Silva-Adaya, Carla Garza-Lombó & María E. Gonsebatt. (2021) Xenobiotic transport and metabolism in the human brain. NeuroToxicology 86, pages 125-138.
Crossref
Crossref
Andrea Perrelli & Saverio Francesco Retta. (2021) Polymorphisms in genes related to oxidative stress and inflammation: Emerging links with the pathogenesis and severity of Cerebral Cavernous Malformation disease. Free Radical Biology and Medicine 172, pages 403-417.
Crossref
Crossref
Daniela Fanni, Federica Pinna, Clara Gerosa, Pasquale Paribello, Bernardo Carpiniello, Gavino Faa & Mirko Manchia. (2021)
Anatomical distribution and expression of
CYP
in humans: Neuropharmacological implications
. Drug Development Research 82:5, pages 628-667.
Crossref
Crossref
Marlaina R. Stocco, Ahmed A. El-Sherbeni, Bin Zhao, Maria Novalen & Rachel F. Tyndale. (2021) The role of CYP2D in rat brain in methamphetamine-induced striatal dopamine and serotonin release and behavioral sensitization. Psychopharmacology 238:7, pages 1791-1804.
Crossref
Crossref
Ewa Niedzielska-Andres, Bartłomiej Rospond, Lucyna Pomierny-Chamioło, Anna Sadakierska-Chudy & Małgorzata Filip. 2021. Handbook of Neurotoxicity. Handbook of Neurotoxicity
1
17
.
Tsukasa Mori, Yoichiro Kitani, Den Hatakeyama, Kazumasa Machida, Naoko Goto-Inoue, Satoshi Hayakawa, Naoyuki Yamamoto, Keiko Kashiwagi & Akihiko Kashiwagi. (2020) Predation threats for a 24-h period activated the extension of axons in the brains of Xenopus tadpoles. Scientific Reports 10:1.
Crossref
Crossref
Guolong Tu, Wenliang Zhan, Yao Sun, Jiamin Wu, Zichao Xiong, Jianfeng Liu, Yuanwei Liu, Haiyue Li & Ying Xia. (2020) CYP2B6 Polymorphisms Are Associated with Ischemic Stroke Risk in a Chinese Han Population. Journal of Molecular Neuroscience 70:7, pages 1130-1139.
Crossref
Crossref
Cole Tolledo, Marlaina R. Stocco, Sharon Miksys, Frank J. Gonzalez & Rachel F. Tyndale. (2020) Human CYP2D6 Is Functional in Brain In Vivo: Evidence from Humanized CYP2D6 Transgenic Mice. Molecular Neurobiology 57:6, pages 2509-2520.
Crossref
Crossref
Robert G. Poston, Lillian Murphy, Ayna Rejepova, Mina Ghaninejad-Esfahani, Joshua Segales, Kimberly Mulligan & Ramendra N. Saha. (2020) Certain ortho-hydroxylated brominated ethers are promiscuous kinase inhibitors that impair neuronal signaling and neurodevelopmental processes. Journal of Biological Chemistry 295:18, pages 6120-6137.
Crossref
Crossref
Chandrali Bhattacharya, Danielle Kirby, Michael Van Stipdonk & Robert E. Stratford. (2018) Comparison of In Vitro Stereoselective Metabolism of Bupropion in Human, Monkey, Rat, and Mouse Liver Microsomes. European Journal of Drug Metabolism and Pharmacokinetics 44:2, pages 261-274.
Crossref
Crossref
Douglas M. McMillan, Sharon Miksys & Rachel F. Tyndale. (2017)
Rat brain
CYP2D
activity alters
in vivo
central oxycodone metabolism, levels and resulting analgesia
. Addiction Biology 24:2, pages 228-238.
Crossref
Crossref
S-Y.A. Tsai, Raphael M. Bendriem & Chun-Ting D. Lee. (2019) The cellular basis of fetal endoplasmic reticulum stress and oxidative stress in drug-induced neurodevelopmental deficits. Neurobiology of Stress 10, pages 100145.
Crossref
Crossref
E. Baez-Jurado, M.A. Rincón-Benavides, O. Hidalgo-Lanussa, G. Guio-Vega, G.M. Ashraf, A. Sahebkar, V. Echeverria, L.M. Garcia-Segura & G.E. Barreto. (2019) Molecular mechanisms involved in the protective actions of Selective Estrogen Receptor Modulators in brain cells. Frontiers in Neuroendocrinology 52, pages 44-64.
Crossref
Crossref
Douglas M. McMillan & Rachel F. Tyndale. (2018) CYP-mediated drug metabolism in the brain impacts drug response. Pharmacology & Therapeutics 184, pages 189-200.
Crossref
Crossref
Aleksi Tornio & Janne T. Backman. 2018. Pharmacogenetics. Pharmacogenetics
3
32
.
Douglas M. McMillan & Rachel F. Tyndale. (2017) Inducing rat brain CYP2D with nicotine increases the rate of codeine tolerance; predicting the rate of tolerance from acute analgesic response. Biochemical Pharmacology 145, pages 158-168.
Crossref
Crossref
Sufang Li, Yihong Yang, Ewa Hoffmann, Rachel F. Tyndale & Elliot A. Stein. (2017) CYP2A6 Genetic Variation Alters Striatal-Cingulate Circuits, Network Hubs, and Executive Processing in Smokers. Biological Psychiatry 81:7, pages 554-563.
Crossref
Crossref
Sam Nightingale, Tran Thi Hong Chau, Martin Fisher, Mark Nelson, Alan Winston, Laura Else, Daniel F. Carr, Steven Taylor, Andrew Ustianowski, David Back, Munir Pirmohamed, Tom Solomon, Jeremy Farrar, M. Estée Törok & Saye Khoo. (2016)
Efavirenz and Metabolites in Cerebrospinal Fluid: Relationship with
CYP2B6
c.516G→T Genotype and Perturbed Blood-Brain Barrier Due to Tuberculous Meningitis
. Antimicrobial Agents and Chemotherapy 60:8, pages 4511-4518.
Crossref
Crossref
Konstantinos Kalafatakis, Georgina M. Russell, Apostolos Zarros & Stafford L. Lightman. (2016) Temporal control of glucocorticoid neurodynamics and its relevance for brain homeostasis, neuropathology and glucocorticoid-based therapeutics. Neuroscience & Biobehavioral Reviews 61, pages 12-25.
Crossref
Crossref
S. Vichi, J. Sandström von Tobel, S. Gemma, S. Stanzel, A. Kopp-Schneider, F. Monnet-Tschudi, E. Testai & M.G. Zurich. (2015) Cell type-specific expression and localization of cytochrome P450 isoforms in tridimensional aggregating rat brain cell cultures. Toxicology in Vitro 30:1, pages 176-184.
Crossref
Crossref
Douglas M McMillan & Rachel F Tyndale. (2015) Nicotine Increases Codeine Analgesia Through the Induction of Brain CYP2D and Central Activation of Codeine to Morphine. Neuropsychopharmacology 40:7, pages 1804-1812.
Crossref
Crossref
Michael S. Gross, Deena M. Butryn, Barbara P. McGarrigle, Diana S. Aga & James R. Olson. (2015) Primary Role of Cytochrome P450 2B6 in the Oxidative Metabolism of 2,2′,4,4′,6-Pentabromodiphenyl Ether (BDE-100) to Hydroxylated BDEs. Chemical Research in Toxicology 28:4, pages 672-681.
Crossref
Crossref
Shikha Srivastava, Anshuman Singh, Rajendra K. Shukla, Vinay K. Khanna & Devendra Parmar. (2015) Effect of prenatal exposure of lindane on alterations in the expression of cerebral cytochrome P450s and neurotransmitter receptors in brain regions. Food and Chemical Toxicology 77, pages 74-81.
Crossref
Crossref
J. Stingl & R. Viviani. (2015)
Polymorphism in
CYP
2D6 and
CYP
2C19, members of the cytochrome P450 mixed‐function oxidase system, in the metabolism of psychotropic drugs
. Journal of Internal Medicine 277:2, pages 167-177.
Crossref
Crossref
Liwei Zheng, Jiaojiao Cao, Dan Lu, Lin Ji, Ying Peng & Jiang Zheng. (2015) Imperatorin Is a Mechanism-Based Inactivator of CYP2B6. Drug Metabolism and Disposition 43:1, pages 82-88.
Crossref
Crossref
Mark J. Canet, Matthew D. Merrell, Bryan G. Harder, Jonathan M. Maher, Tongde Wu, Andrew J. Lickteig, Jonathan P. Jackson, Donna D. Zhang, Masayuki Yamamoto & Nathan J. Cherrington. (2015)
Identification of a Functional Antioxidant Response Element within the Eighth Intron of the Human
ABCC3
Gene
. Drug Metabolism and Disposition 43:1, pages 93-99.
Crossref
Crossref
Johanna Penell, Lars Lind, Tove Fall, Anne-Christine Syvänen, Tomas Axelsson, Per Lundmark, Andrew P Morris, Cecilia Lindgren, Anubha Mahajan, Samira Salihovic, Bert van Bavel, Erik Ingelsson & P Monica Lind. (2014) Genetic variation in the CYP2B6 Gene is related to circulating 2,2’,4,4’-tetrabromodiphenyl ether (BDE-47) concentrations: an observational population-based study. Environmental Health 13:1.
Crossref
Crossref
Lucio G. Costa, Rian de Laat, Sara Tagliaferri & Claudia Pellacani. (2014) A mechanistic view of polybrominated diphenyl ether (PBDE) developmental neurotoxicity. Toxicology Letters 230:2, pages 282-294.
Crossref
Crossref
Anne M. Riederer, Radhika Dhingra, Benjamin C. Blount & Kyle Steenland. (2014) Predictors of Blood Trihalomethane Concentrations in NHANES 1999–2006. Environmental Health Perspectives 122:7, pages 695-702.
Crossref
Crossref
Vinay K. Tripathi, Vivek Kumar, Abhishek K. Singh, Mahendra P. Kashyap, Sadaf Jahan, Ankita Pandey, Sarfaraz Alam, Feroz Khan, Vinay K. Khanna, Sanjay Yadav, Mohtshim Lohani & Aditya B. Pant. (2014) Monocrotophos Induces the Expression and Activity of Xenobiotic Metabolizing Enzymes in Pre-Sensitized Cultured Human Brain Cells. PLoS ONE 9:3, pages e91946.
Crossref
Crossref
Pierre BaumannVijayalakshmi Ravindranath. 2014. CYP2D6: Genetics, Pharmacology and Clinical Relevance. CYP2D6: Genetics, Pharmacology and Clinical Relevance
102
116
.
Xiaoshuang Wang, Jie Li, Guicheng Dong & Jiang Yue. (2014) The endogenous substrates of brain CYP2D. European Journal of Pharmacology 724, pages 211-218.
Crossref
Crossref
Ewa Niedzielska, Bartłomiej Rospond, Lucyna Pomierny-Chamioło, Anna Sadakierska-Chudy & Małgorzata Filip. 2014. Handbook of Neurotoxicity. Handbook of Neurotoxicity
1525
1541
.
Jun Qian, Zhangfa Song, Yinxiang Lv & Xuefeng Huang. (2013) CYP2E1 T7632A and 9-bp insertion polymorphisms and colorectal cancer risk: a meta-analysis based on 4,592 cases and 5,918 controls. Tumor Biology 34:4, pages 2225-2231.
Crossref
Crossref
Kaidi Zhou, Jibran Y. Khokhar, Bin Zhao & Rachel F. Tyndale. (2013) First demonstration that brain CYP2D-mediated opiate metabolic activation alters analgesia in vivo. Biochemical Pharmacology 85:12, pages 1848-1855.
Crossref
Crossref
Maria Luisa Feo, Michael S. Gross, Barbara P. McGarrigle, Ethel Eljarrat, Damià Barceló, Diana S. Aga & James R. Olson. (2013) Biotransformation of BDE-47 to Potentially Toxic Metabolites Is Predominantly Mediated by Human CYP2B6. Environmental Health Perspectives 121:4, pages 440-446.
Crossref
Crossref
O. V. Galkina. (2013) The specific features of free-radical processes and the antioxidant defense in the adult brain. Neurochemical Journal 7:2, pages 89-97.
Crossref
Crossref
J C Stingl, J Brockmöller & R Viviani. (2012) Genetic variability of drug-metabolizing enzymes: the dual impact on psychiatric therapy and regulation of brain function. Molecular Psychiatry 18:3, pages 273-287.
Crossref
Crossref
Ann F. Hubbs, Linda M. Sargent, Dale W. Porter, Tina M. Sager, Bean T. Chen, David G. Frazer, Vincent Castranova, Krishnan Sriram, Timothy R. Nurkiewicz, Steven H. Reynolds, Lori A. Battelli, Diane Schwegler-Berry, Walter McKinney, Kara L. Fluharty & Robert R. Mercer. (2013) Nanotechnology: Toxicologic Pathology. Toxicologic Pathology 41:2, pages 395-409.
Crossref
Crossref
Ann Hubbs, Dale W. Porter, Robert Mercer, Vincent Castranova, Linda Sargent & Krishnan Sriram. 2013. Haschek and Rousseaux's Handbook of Toxicologic Pathology. Haschek and Rousseaux's Handbook of Toxicologic Pathology
1373
1419
.
Alexander V. LyubimovShalu Jhajra, Ninad Ramesh Varkhede, Deepak Suresh Ahire, Bukke Vidyasagar Naik, Bhagwat Prasad, Jyoti Paliwal & Saranjit Singh. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions
1
99
.
Nicholas Baker, Florian Wolschin & Gro V. Amdam. (2012) Age-related learning deficits can be reversible in honeybees Apis mellifera. Experimental Gerontology 47:10, pages 764-772.
Crossref
Crossref
Amandeep Mann, Sharon L. Miksys, Andrea Gaedigk, Stephen J. Kish, Deborah C. Mash & Rachel F. Tyndale. (2012) The neuroprotective enzyme CYP2D6 increases in the brain with age and is lower in Parkinson's disease patients. Neurobiology of Aging 33:9, pages 2160-2171.
Crossref
Crossref
Victor A. Voicu, Jose de Leon, Andrei Valentin Medvedovici, Flavian Ştefan Rădulescu & Dalia Simona Miron. (2012) New insights on the consequences of biotransformation processes on the distribution and pharmacodynamic profiles of some neuropsychotropic drugs. European Neuropsychopharmacology 22:5, pages 319-329.
Crossref
Crossref
Iris Shichor, Noam Shomron, Michael W. Lawlor, Seul A. Bae, Janet Zoldan, Robert Langer & Daniel S. Kohane. (2012) Toxicogenomic analysis of a sustained release local anesthetic delivery system. Biomaterials 33:13, pages 3586-3593.
Crossref
Crossref
Alexander V. LyubimovUlrich M. Zanger. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions
1
36
.
Maria Brandmann, Ketki Tulpule, Maike M. Schmidt & Ralf Dringen. (2011) The antiretroviral protease inhibitors indinavir and nelfinavir stimulate Mrp1‐mediated GSH export from cultured brain astrocytes. Journal of Neurochemistry 120:1, pages 78-92.
Crossref
Crossref
Mercè Correa, John D. Salamone, Kristen N. Segovia, Marta Pardo, Rosanna Longoni, Liliana Spina, Alessandra T. Peana, Stefania Vinci & Elio Acquas. (2012) Piecing together the puzzle of acetaldehyde as a neuroactive agent. Neuroscience & Biobehavioral Reviews 36:1, pages 404-430.
Crossref
Crossref
Ewa Bromek, Anna Haduch, Krystyna Gołembiowska & Władysława A. Daniel. (2011) Cytochrome P450 mediates dopamine formation in the brain in vivo. Journal of Neurochemistry 118:5, pages 806-815.
Crossref
Crossref
Chitra Sridar, Natasha T. Snider & Paul F. Hollenberg. (2011) Anandamide Oxidation by Wild-Type and Polymorphically Expressed CYP2B6 and CYP2D6. Drug Metabolism and Disposition 39:5, pages 782-788.
Crossref
Crossref
Lindsay B. Hough, Julia W. Nalwalk, Jun Yang, Jennie L. Conroy, Melissa A. VanAlstine, Weizhu Yang, Joseph Gargano, Zhixing Shan, Shao-Zhong Zhang, Mark P. Wentland, James G. Phillips, Brian I. Knapp, Jean M. Bidlack, Obbe P. Zuiderveld, Rob Leurs & Xinxin Ding. (2011) Brain P450 epoxygenase activity is required for the antinociceptive effects of improgan, a nonopioid analgesic. Pain 152:4, pages 878-887.
Crossref
Crossref
J C Stingl (formerly Kirchheiner)R Viviani. (2011) CYP2D6 in the Brain: Impact on Suicidality. Clinical Pharmacology & Therapeutics 89:3, pages 352-353.
Crossref
Crossref
Jibran Y Khokhar & Rachel F Tyndale. (2010) Drug Metabolism within the Brain Changes Drug Response: Selective Manipulation of Brain CYP2B Alters Propofol Effects. Neuropsychopharmacology 36:3, pages 692-700.
Crossref
Crossref
Anna Haduch, Ewa Bromek & Władysława A. Daniel. (2011) The effect of psychotropic drugs on cytochrome P450 2D (CYP2D) in rat brain. European Journal of Pharmacology 651:1-3, pages 51-58.
Crossref
Crossref
Joseph Friedman. 2011. Oxidative Stress and Free Radical Damage in Neurology. Oxidative Stress and Free Radical Damage in Neurology
19
27
.
Wayne E. Pratt & Megan E. Connolly. (2010) Contrasting effects of systemic and central sibutramine administration on the intake of a palatable diet in the rat. Neuroscience Letters 484:1, pages 30-34.
Crossref
Crossref
Caroline F. Thorn, Jatinder K. Lamba, Vishal Lamba, Teri E. Klein & Russ B. Altman. (2010) PharmGKB summary: very important pharmacogene information for CYP2B6. Pharmacogenetics and Genomics 20:8, pages 520-523.
Crossref
Crossref
Eugene G. Hrycay & Stelvio M. Bandiera. 2010. Pharmaceutical Sciences Encyclopedia. Pharmaceutical Sciences Encyclopedia
1
70
.
Natasha T. Snider, Vyvyca J. Walker & Paul F. Hollenberg. (2010) Oxidation of the Endogenous Cannabinoid Arachidonoyl Ethanolamide by the Cytochrome P450 Monooxygenases: Physiological and Pharmacological Implications. Pharmacological Reviews 62:1, pages 136-154.
Crossref
Crossref
Vadim Yuferov, Orna Levran, Dmitri Proudnikov, David A. Nielsen & Mary Jeanne Kreek. (2010) Search for genetic markers and functional variants involved in the development of opiate and cocaine addiction and treatment. Annals of the New York Academy of Sciences 1187:1, pages 184-207.
Crossref
Crossref
Ewa Bromek, Anna Haduch & Władysława A. Daniel. (2010) The ability of cytochrome P450 2D isoforms to synthesize dopamine in the brain: An in vitro study. European Journal of Pharmacology 626:2-3, pages 171-178.
Crossref
Crossref
Ralf P. Meyer, Georgios Pantazis, Nina Killer, Carolin Bürck, Ricarda Schwab, Monika Brandt, Rolf Knoth & Marcel Gehlhaus. 2010. Hormones of the Limbic System. Hormones of the Limbic System
87
106
.
Tibor M. Brunt, Sander Rigter, Jani Hoek, Neeltje Vogels, Peter Van Dijk & Raymond J. M. Niesink. (2009) An analysis of cocaine powder in the Netherlands: content and health hazards due to adulterants. Addiction 104:5, pages 798-805.
Crossref
Crossref
Mercè Correa, Cristina Viaggi, Miguel A. Escrig, María Pascual, Consuelo Guerri, Francesca Vaglini, Carlos M.G. Aragon & Giovanni U. Corsini. (2009) Ethanol intake and ethanol-induced locomotion and locomotor sensitization in Cyp2e1 knockout mice. Pharmacogenetics and Genomics 19:3, pages 217-225.
Crossref
Crossref
Sharon Miksys & Rachel F Tyndale. (2008) Brain Drug-Metabolizing Cytochrome P450 Enzymes are Active In Vivo, Demonstrated by Mechanism-Based Enzyme Inhibition. Neuropsychopharmacology 34:3, pages 634-640.
Crossref
Crossref
Jill C. Mwenifumbo & Rachel F. Tyndale. 2009. Nicotine Psychopharmacology. Nicotine Psychopharmacology
235
259
.
Tomás Herraiz, Hugo Guillén & Vicente J. Arán. (2008) Oxidative Metabolism of the Bioactive and Naturally Occurring β-Carboline Alkaloids, Norharman and Harman, by Human Cytochrome P450 Enzymes. Chemical Research in Toxicology 21:11, pages 2172-2180.
Crossref
Crossref
Jacek Wójcikowski, Krystyna Gołembiowska & Władysława Anna Daniel. (2008) Regulation of liver cytochrome P450 by activation of brain dopaminergic system: Physiological and pharmacological implications. Biochemical Pharmacology 76:2, pages 258-267.
Crossref
Crossref
Fabien Dutheil, Philippe Beaune & Marie-Anne Loriot. (2008) Xenobiotic metabolizing enzymes in the central nervous system: Contribution of cytochrome P450 enzymes in normal and pathological human brain. Biochimie 90:3, pages 426-436.
Crossref
Crossref
Mikl?s P?ter Kalapos. (2008) METHYLGLYOXAL AND GLUCOSE METABOLISM: A HISTORICAL PERSPECTIVE AND FUTURE AVENUES FOR RESEARCH. Drug Metabolism and Drug Interactions 23:1-2.
Crossref
Crossref
Diana Pendicheva, Ivo Duhlenski, Tony Donchev, Vladimir Nakov & Antoaneta Pandurska. (2008) Distribution of Cytochrome P450 2D6 in the human brain: potential role in psychotropic drug response. Annals of General Psychiatry 7:Suppl 1, pages S127.
Crossref
Crossref
Huijun Z. Ring, Ana M. Valdes, Denise M. Nishita, Suman Prasad, Peyton Jacob, Rachel F. Tyndale, Gary E. Swan & Neal L. Benowitz. (2007) Gene–gene interactions between CYP2B6 and CYP2A6 in nicotine metabolism. Pharmacogenetics and Genomics 17:12, pages 1007-1015.
Crossref
Crossref
Hsia-lien Lin, Eugene Myshkin, Lucy Waskell & Paul F. Hollenberg. (2007) Peroxynitrite Inactivation of Human Cytochrome P450s 2B6 and 2E1: Heme Modification and Site-Specific Nitrotyrosine Formation. Chemical Research in Toxicology 20:11, pages 1612-1622.
Crossref
Crossref
Eriko Higashi, Tatsuki Fukami, Masahiro Itoh, Satoru Kyo, Masaki Inoue, Tsuyoshi Yokoi & Miki Nakajima. (2007) Human CYP2A6 Is Induced by Estrogen via Estrogen Receptor. Drug Metabolism and Disposition 35:10, pages 1935-1941.
Crossref
Crossref
Miklós Péter Kalapos. (2007) What Is the Antiseizure Activity of Acetone Due To?. Epilepsia 48:10, pages 2002-2003.
Crossref
Crossref
Eriko Higashi, Miki Nakajima, Miki Katoh, Shogo Tokudome & Tsuyoshi Yokoi. (2007) Inhibitory Effects of Neurotransmitters and Steroids on Human CYP2A6. Drug Metabolism and Disposition 35:4, pages 508-514.
Crossref
Crossref
Mikl?s P?ter Kalapos. (2007) Possible mechanism for the effect of ketogenic diet in cases of uncontrolled seizures. Medical Hypotheses 68:6, pages 1382-1388.
Crossref
Crossref
Ryan SwinneyStephanie HsuGail Tomlinson. (2023) Phase I and Phase II Enzyme Polymorphisms and Childhood Cancer. Journal of Investigative Medicine 54:6, pages 303-320.
Crossref
Crossref
Nidhi Kapoor, Aditya B. Pant, Alok Dhawan, Uppendra N. Dwievedi, Yogendra K. Gupta, Prahlad K. Seth & Devendra Parmar. (2006) Differences in sensitivity of cultured rat brain neuronal and glial cytochrome P450 2E1 to ethanol. Life Sciences 79:16, pages 1514-1522.
Crossref
Crossref
Sanja KezicFlorentine Calkoen, Mira AM Wenker, John JL Jacobs & Maarten M Verberk. (2016) Genetic polymorphism of metabolic enzymes modifies the risk of chronic solvent-induced encephalopathy. Toxicology and Industrial Health 22:7, pages 281-289.
Crossref
Crossref
Namandjé N. Bumpus, Ute M. Kent & Paul F. Hollenberg. (2006) Metabolism of Efavirenz and 8-Hydroxyefavirenz by P450 2B6 Leads to Inactivation by Two Distinct Mechanisms. Journal of Pharmacology and Experimental Therapeutics 318:1, pages 345-351.
Crossref
Crossref
Barry Halliwell. (2006) Oxidative stress and neurodegeneration: where are we now?. Journal of Neurochemistry 97:6, pages 1634-1658.
Crossref
Crossref
Meenal Joshi & Rachel F. Tyndale. (2006) INDUCTION AND RECOVERY TIME COURSE OF RAT BRAIN CYP2E1 AFTER NICOTINE TREATMENT. Drug Metabolism and Disposition 34:4, pages 647-652.
Crossref
Crossref
Sandra Coecke, Hans Ahr, Bas J. Blaauboer, Susanne Bremer, Silvia Casati, Josè Castell, Robert Combes, Raffaella Corvi, Charles L. Crespi, Michael L. Cunningham, Greetje Elaut, Brighitta Eletti, Andreas Freidig, Alessandra Gennari, Jean-François Ghersi-Egea, Andre Guillouzo, Thomas Hartung, Peter Hoet, Magnus Ingelman-Sundberg, Sharon Munn, Walter Janssens, Bernhard Ladstetter, David Leahy, Anthony Long, Annarita Meneguz, Mario Monshouwer, Siegfried Morath, Fred Nagelkerke, Olavi Pelkonen, Jessica Ponti, Pilar Prieto, Lysianne Richert, Enrico Sabbioni, Beatrice Schaack, Winfried Steiling, Emanuela Testai, Joan-Albert Vericat & Andrew Worth. (2019)
Metabolism: A Bottleneck in
In Vitro
Toxicological Test Development
. Alternatives to Laboratory Animals 34:1, pages 49-84.
Crossref
Crossref
Sandra Coecke, Chantra Eskes, Joanne Gartlon, Agnieszka Kinsner, Anna Price, Erwin van Vliet, Pilar Prieto, Monica Boveri, Susanne Bremer, Sarah Adler, Cristian Pellizzer, Albrecht Wendel & Thomas Hartung. (2006) The value of alternative testing for neurotoxicity in the context of regulatory needs. Environmental Toxicology and Pharmacology 21:2, pages 153-167.
Crossref
Crossref
S. Miksys & R. F. Tyndale. 2006. Parkinson’s Disease and Related Disorders. Parkinson’s Disease and Related Disorders
177
180
.
Jan H.C.M. Lammers, Wim J.A. Meuling, Hans Muijser, Andreas P. Freidig & Jos G.M. Bessems. (2005) Neurobehavioural evaluation and kinetics of inhalation of constant or fluctuating toluene concentrations in human volunteers. Environmental Toxicology and Pharmacology 20:3, pages 431-442.
Crossref
Crossref
Hsia-lien Lin, Haoming Zhang, Lucy Waskell & Paul F. Hollenberg. (2005) The Highly Conserved Glu149 and Tyr190 Residues Contribute To Peroxynitrite-Mediated Nitrotyrosine Formation and the Catalytic Activity of Cytochrome P450 2B1. Chemical Research in Toxicology 18:8, pages 1203-1210.
Crossref
Crossref