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Research Article

Acetaminophen‐Induced Hepatotoxicity: Role of Metabolic Activation, Reactive Oxygen/Nitrogen Species, and Mitochondrial Permeability Transition

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Pages 805-822 | Published online: 25 Oct 2004

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Amal S Abdel-Azeem, Amany M Hegazy, Khadiga S Ibrahim, Abdel-Razik H. Farrag & Eman M. El-Sayed. (2013) Hepatoprotective, Antioxidant, and Ameliorative Effects of Ginger (Zingiber officinale Roscoe) and Vitamin E in Acetaminophen Treated Rats. Journal of Dietary Supplements 10:3, pages 195-209.
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Chun-Yuh Teng, Yi-Liang Lai, Hai-I Huang, Wen-Hsiu Hsu, Chen-Chieh Yang & Wu-Hsien Kuo. (2012) Tournefortia sarmentosa extract attenuates acetaminophen-induced hepatotoxicity. Pharmaceutical Biology 50:3, pages 291-396.
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Hartmut Jaeschke, Mitchell R. McGill & Anup Ramachandran. (2012) Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: Lessons learned from acetaminophen hepatotoxicity. Drug Metabolism Reviews 44:1, pages 88-106.
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Jane F. Maddox, Chidozie J. Amuzie, Maoxiang Li, Sandra W. Newport, Erica Sparkenbaugh, Christopher F. Cuff, James J. Pestka, Glenn H. Cantor, Robert A. Roth & Patricia E. Ganey. (2009) Bacterial- and Viral-Induced Inflammation Increases Sensitivity to Acetaminophen Hepatotoxicity. Journal of Toxicology and Environmental Health, Part A 73:1, pages 58-73.
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Bo Wen & William L Fitch. (2009) Analytical strategies for the screening and evaluation of chemically reactive drug metabolites. Expert Opinion on Drug Metabolism & Toxicology 5:1, pages 39-55.
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