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Original

Niemann Pick Type C Disease as a Model for Defects in Neurosteroidogenesis

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Pages 727-735 | Published online: 07 Jul 2009

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Read on this site (2)

Moneek Madra & Stephen L Sturley. (2010) Niemann–Pick type C pathogenesis and treatment: from statins to sugars. Clinical Lipidology 5:3, pages 387-395.
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Articles from other publishers (22)

Defan Wang, Yedong Tang & Zhengchao Wang. (2023) Role of sphingolipid metabolites in the homeostasis of steroid hormones and the maintenance of testicular functions. Frontiers in Endocrinology 14.
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Ehab M. B. Mahdy, Sherif F. El-Sharabasy & Maiada M. El-Dawayati. 2022. Nutraceuticals Production from Plant Cell Factory. Nutraceuticals Production from Plant Cell Factory 265 285 .
Jennifer C. Naylor, Jason D. Kilts, Lawrence J. Shampine, Gillian J. Parke, H. Ryan Wagner, Steven T. Szabo, Karen D. Smith, Trina B. Allen, Emily G. Telford-Marx, Charlotte E. Dunn, Brian T. Cuffe, Susan H. O’Loughlin & Christine E. Marx. (2020) Effect of Pregnenolone vs Placebo on Self-reported Chronic Low Back Pain Among US Military Veterans. JAMA Network Open 3:3, pages e200287.
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Preetismita Borah & Bimal Krishna Banik. 2020. Green Approaches in Medicinal Chemistry for Sustainable Drug Design. Green Approaches in Medicinal Chemistry for Sustainable Drug Design 449 490 .
Marc C. Patterson & Steven U. Walkley. (2017) Niemann-Pick disease, type C and Roscoe Brady. Molecular Genetics and Metabolism 120:1-2, pages 34-37.
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Abdulmaged M. Traish. (2015) The Impact of the 5α-Reductase Inhibitors (5α-RIs) on Male Sexual Function and Psychological Well-Being. Current Sexual Health Reports 7:4, pages 210-219.
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Jennifer C. Naylor, Jason D. Kilts, Steven T. Szabo, Charlotte E. Dunn, Francis J. Keefe, Larry A. Tupler, Lawrence J. Shampine, Rajendra A. Morey, Jennifer L. Strauss, Robert M. Hamer, H. Ryan Wagner & Christine E. Marx. (2015) Allopregnanolone Levels are Inversely Associated with Self-Reported Pain Symptoms in U.S.Iraq and Afghanistan-Era Veterans: Implications for Biomarkers and Therapeutics. Pain Medicine, pages n/a-n/a.
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Marina Hovakimyan, Anja Meyer, Jan Lukas, Jiankai Luo, Volker Gudziol, Thomas Hummel, Arndt Rolfs, Andreas Wree & Martin Witt. (2013) Olfactory Deficits in Niemann-Pick Type C1 (NPC1) Disease. PLoS ONE 8:12, pages e82216.
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Abdulmaged M. Traish. (2012) 5α-Reductases In Human Physiology: an Unfolding Story. Endocrine Practice 18:6, pages 965-975.
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Shuhua Chen, Jun Ming Wang, Ronald W. Irwin, Jia Yao, Lifei Liu & Roberta Diaz Brinton. (2011) Allopregnanolone Promotes Regeneration and Reduces β-Amyloid Burden in a Preclinical Model of Alzheimer's Disease. PLoS ONE 6:8, pages e24293.
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Jason D. Kilts, Larry A. Tupler, Francis J. Keefe, Victoria M. Payne, Robert M. Hamer, Jennifer C. Naylor, Rohana P. Calnaido, Rajendra A. Morey, Jennifer L. Strauss, Gillian Parke, Mark W. Massing, Nagy A. Youssef, Lawrence J. Shampine & Christine E. Marx. (2010) Neurosteroids and Self-Reported Pain in Veterans Who Served in the U.S. Military after September 11, 2001. Pain Medicine 11:10, pages 1469-1476.
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Natasha C. Lucki & Marion B. Sewer. (2010) The interplay between bioactive sphingolipids and steroid hormones. Steroids 75:6, pages 390-399.
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Mark Charman, Barry E. Kennedy, Nolan Osborne & Barbara Karten. (2010) MLN64 mediates egress of cholesterol from endosomes to mitochondria in the absence of functional Niemann-Pick Type C1 protein. Journal of Lipid Research 51:5, pages 1023-1034.
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Sònia Darbra & Marc Pallarès. (2009) Neonatal allopregnanolone increases novelty‐directed locomotion and disrupts behavioural responses to GABA A receptor modulators in adulthood . International Journal of Developmental Neuroscience 27:6, pages 617-625.
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Jean Luc Do Rego, Jae Young Seong, Delphine Burel, Jerôme Leprince, Van Luu-The, Kazuyoshi Tsutsui, Marie-Christine Tonon, Georges Pelletier & Hubert Vaudry. (2009) Neurosteroid biosynthesis: Enzymatic pathways and neuroendocrine regulation by neurotransmitters and neuropeptides. Frontiers in Neuroendocrinology 30:3, pages 259-301.
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Barbara Karten, Kyle B. Peake & Jean E. Vance. (2009) Mechanisms and consequences of impaired lipid trafficking in Niemann–Pick type C1-deficient mammalian cells. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1791:7, pages 659-670.
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Jun Ming Wang, Lifei Liu, Ronald W. Irwin, Shuhua Chen & Roberta Diaz Brinton. (2008) Regenerative potential of allopregnanolone. Brain Research Reviews 57:2, pages 398-409.
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Mark Haskins & Urs Giger. 2008. Clinical Biochemistry of Domestic Animals. Clinical Biochemistry of Domestic Animals 731 749 .
Natasha C. Lucki & Marion B. Sewer. 2008. Lipids in Health and Disease. Lipids in Health and Disease 387 412 .
Stephen P. Voght, Megan L. Fluegel, Laurie A. Andrews & Leo J. Pallanck. (2007) Drosophila NPC1b Promotes an Early Step in Sterol Absorption from the Midgut Epithelium. Cell Metabolism 5:3, pages 195-205.
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C.A.F. Teixeira, S. Lin, M. Mangas, R. Quinta, C.J.P. Bessa, C. Ferreira, M.C. Sá Miranda, R-M.N. Boustany & M.G. Ribeiro. (2006) Gene expression profiling in vLINCL CLN6-deficient fibroblasts: Insights into pathobiology. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1762:7, pages 637-646.
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Christine E Marx, Robert D Stevens, Lawrence J Shampine, Veska Uzunova, William T Trost, Marian I Butterfield, Mark W Massing, Robert M Hamer, A Leslie Morrow & Jeffrey A Lieberman. (2005) Neuroactive Steroids are Altered in Schizophrenia and Bipolar Disorder: Relevance to Pathophysiology and Therapeutics. Neuropsychopharmacology 31:6, pages 1249-1263.
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