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Original Articles

SAFFRON—RENEWED INTEREST IN AN ANCIENT SPICE

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Pages 39-59 | Published online: 05 Mar 2007

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (15)

Luca Giupponi, Valeria Leoni, Stefano Sala, Annamaria Giorgi & Danilo Bertoni. (2023) Saffron growing in Italy: a sustainable secondary activity for farms in hilly and sub-mountain areas. International Journal of Agricultural Sustainability 21:1.
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Laleh Arzi & Reyhane Hoshyar. (2022) Saffron anti-metastatic properties, ancient spice novel application. Critical Reviews in Food Science and Nutrition 62:14, pages 3939-3950.
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Samareh Babaei, Vahid Niknam & Mehrdad Behmanesh. (2021) Comparative effects of nitric oxide and salicylic acid on salinity tolerance in saffron (Crocus sativus). Plant Biosystems - An International Journal Dealing with all Aspects of Plant Biology 155:1, pages 73-82.
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Annapoorna Sreedhar, Jun Li & Yunfeng Zhao. (2018) Next-Gen Therapeutics for Skin Cancer: Nutraceuticals. Nutrition and Cancer 70:5, pages 697-709.
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Concetta Condurso, Fabrizio Cincotta, Gianluca Tripodi & Antonella Verzera. (2017) Bioactive volatiles in Sicilian (South Italy) saffron: safranal and its related compounds. Journal of Essential Oil Research 29:3, pages 221-227.
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Samaneh Gazeran, Faezeh Tajalli & Ali Mohamadi Sani. (2016) Effect of Ultrasonic Extraction on Qualitative Parameters of Saffron Edible Extract. Journal of Essential Oil Bearing Plants 19:5, pages 1286-1291.
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Shahrzad Zamani Taghizadeh Rabe, Maryam Sahebari, Zohreh Mahmoudi, Hossein Hosseinzadeh, Dariush Haghmorad, Nafise Tabasi, Maryam Rastin, Mahdieh Khazaee & Mahmoud Mahmoudi. (2015) Inhibitory effect of Crocus sativus L. ethanol extract on adjuvant-induced arthritis. Food and Agricultural Immunology 26:2, pages 170-180.
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AnnaM. D’Alessandro, Andrea Mancini, Anna Rita Lizzi, Angela De Simone, Carmine Esposito Marroccella, Giovanni Luca Gravina, Carla Tatone & Claudio Festuccia. (2013) Crocus Sativus Stigma Extract and Its Major Constituent Crocin Possess Significant Antiproliferative Properties Against Human Prostate Cancer. Nutrition and Cancer 65:6, pages 930-942.
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Zhiyu Zhang, Chong-Zhi Wang, Xiao-Dong Wen, Yukihiro Shoyama & Chun-Su Yuan. (2013) Role of saffron and its constituents on cancer chemoprevention. Pharmaceutical Biology 51:7, pages 920-924.
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Bahadir Acar, Hasan Sadikoglu & Mehmet Ozkaymak. (2011) Freeze Drying of Saffron (Crocus sativus L.). Drying Technology 29:14, pages 1622-1627.
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S. Zahra Bathaie & S. Zeinab Mousavi. (2010) New Applications and Mechanisms of Action of Saffron and its Important Ingredients. Critical Reviews in Food Science and Nutrition 50:8, pages 761-786.
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M. Carmona, A. Zalacain, M.R. Salinas & G.L. Alonso. (2007) A New Approach to Saffron Aroma. Critical Reviews in Food Science and Nutrition 47:2, pages 145-159.
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E. Rodríguez-Bustamante & S. Sánchez. (2007) Microbial Production of C13-Norisoprenoids and Other Aroma Compounds via Carotenoid Cleavage. Critical Reviews in Microbiology 33:3, pages 211-230.
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Andreas Degenhardt & Peter Winterhalter. (2001) ISOLATION OF NATURAL PIGMENTS BY HIGH SPEED CCC. Journal of Liquid Chromatography & Related Technologies 24:11-12, pages 1745-1764.
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Articles from other publishers (201)

Adal Mena-García, María L. Sanz, Marina Díez-Municio & Ana I. Ruiz-Matute. (2023) A Combined Gas and Liquid Chromatographic Approach for Quality Evaluation of Saffron-Based Food Supplements. Foods 12:22, pages 4071.
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Shamsun Nisa, Suruchi Gupta & Ravail Singh. (2023) Molecular adaptation and codon usage bias analysis of Heterodera glycines and Heterodera avenae in saffron (Crocus sativus) corms from Jammu and Kashmir. Physiological and Molecular Plant Pathology 128, pages 102131.
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Ali Mohammad Pourbagher‐Shahri & Fatemeh Forouzanfar. (2023) Saffron ( Crocus sativus ) and its constituents for pain management: A review of current evidence . Phytotherapy Research 37:11, pages 5041-5057.
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Feriala A. Abu Safe, Ahmed N. Badr, Mohamed G. Shehata & Gharieb S. El-Sayyad. (2023) Antimicrobial and anti-aflatoxigenic activities of nanoemulsions based on Achillea millefolium and Crocus sativus flower extracts as green promising agents for food preservatives. BMC Microbiology 23:1.
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Charles Spence. (2023) Saffron: The colourful spice. International Journal of Gastronomy and Food Science, pages 100821.
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S. Du, J. Lu, B. Hu, T. Han, Z. Kong, L. Qin & B. Zhu. (2023) Endophytic Fungi Prevent Corm Rot Disease and Stimulate the Growth and Metabolism of Crocus sativus. Applied Biochemistry and Microbiology 59:4, pages 503-510.
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Micha Horacek, Mounira Lage & Jyoti Vakhlu. (2023) Exploring the Potential of 87Sr/86Sr Isotope Ratio with Strontium and Rubidium Levels to Assess the Geographic Origin of Saffron. Foods 12:15, pages 2830.
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Daliane R. C. da Silva, Sivuyisiwe Mapukata, Sara Currie, Alexandros A. Kitos, Anabel E. Lanterna, Tebello Nyokong & Juan C. Scaiano. (2023) Fibrous TiO 2 Alternatives for Semiconductor-Based Catalysts for Photocatalytic Water Remediation Involving Organic Contaminants . ACS Omega 8:24, pages 21585-21593.
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Sarah Al Gharib, Pierre Archirel, Daniel Adjei, Jacqueline Belloni & Mehran Mostafavi. (2023) Unveiling the Intimate Mechanism of the Crocin Antioxidant Properties by Radiolytic Analysis and Molecular Simulations. Antioxidants 12:6, pages 1202.
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Parya Ezati, Ajahar Khan, Jong-Whan Rhim, Swarup Roy & Zahoor Ul Hassan. (2022) Saffron: Perspectives and Sustainability for Active and Intelligent Food Packaging Applications. Food and Bioprocess Technology 16:6, pages 1177-1196.
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Nadia Naim, Ibtissame Guirrou, Marie‐Laure Fauconnier, Hanine Hafida, Abdessalem Tahiri, Ilham Madani, Rachid Lahlali & Said Ennahli. (2023) Chemical, biochemical and volatile profiles of saffron ( Crocus sativus L.) from different growing areas of Morocco . JSFA reports 3:5, pages 233-247.
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A. Annam Renita, Tejal K. Gajaria, S. Sathish, J. Aravind Kumar, D. Shanthana Lakshmi, Joanna Kujawa & Wojciech Kujawski. (2023) Progress and Prospective of the Industrial Development and Applications of Eco-Friendly Colorants: An Insight into Environmental Impact and Sustainability Issues. Foods 12:7, pages 1521.
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Mohammed E. El-Mahrouk, Yaser Hassan Dewir, Hassan El-Ramady & Mayada Kadri Seliem. (2023) Vegetative Growth and Productivity of Potted Crocus sativus in Different Growing Media. Horticulturae 9:3, pages 377.
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Mikael Larsson & Brendan Foley. (2023) The king’s spice cabinet–Plant remains from Gribshunden, a 15th century royal shipwreck in the Baltic Sea. PLOS ONE 18:1, pages e0281010.
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Aabid M. Rather, Sufiya Rashid, Rubaya Sultan, Irshad A. Nawchoo, Ishfaq Ahmad Wani & Azra N. Kamili. (2022) Hurdles and clarifications for the cultivation of saffron in Jammu and Kashmir. Journal of Agriculture and Food Research 10, pages 100344.
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Alberto José López-Jiménez, Lucía Morote, Enrique Niza, María Mondéjar, Ángela Rubio-Moraga, Gianfranco Diretto, Oussama Ahrazem & Lourdes Gómez-Gómez. (2022) Subfunctionalization of D27 Isomerase Genes in Saffron. International Journal of Molecular Sciences 23:18, pages 10543.
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Tahir ul Gani Mir, Atif Khurshid Wani, Jaskaran Singh & Saurabh Shukla. (2022) Therapeutic application and toxicity associated with Crocus sativus (saffron) and its phytochemicals. Pharmacological Research - Modern Chinese Medicine 4, pages 100136.
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Yaser Hassan Dewir & Abdullah Alsadon. (2022) Effects of Nutrient Solution Electrical Conductivity on the Leaf Gas Exchange, Biochemical Stress Markers, Growth, Stigma Yield, and Daughter Corm Yield of Saffron in a Plant Factory. Horticulturae 8:8, pages 673.
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Amit Kumar, Mamta Devi, Rakesh Kumar & Sanjay Kumar. (2022) Introduction of high-value Crocus sativus (saffron) cultivation in non-traditional regions of India through ecological modelling. Scientific Reports 12:1.
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Elisabetta De Angelis, Rosa Pilolli, Alice Bejjani, Rocco Guagnano, Cristiano Garino, Marco Arlorio & Linda Monaci. (2021) Optimization of an Untargeted DART-HRMS Method Envisaging Identification of Potential Markers for Saffron Authenticity Assessment. Foods 10:6, pages 1238.
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S. Kırıcı, B. Sevindik & Y. Yalçın Mendi. (2020) Production of saffron in Turkey. Acta Horticulturae:1287, pages 403-410.
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Kyriaki Hatziagapiou & George I. Lambrou. (2020) Anti-toxicant Properties of Saffron and Relevance to Protection from Toxins and Drugs. Current Bioactive Compounds 16:3, pages 265-283.
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Oussama Ahrazem, Javier Argandoña, Alessia Fiore, Andrea Rujas, Ángela Rubio-Moraga, Raquel Castillo & Lourdes Gómez-Gómez. (2019) Multi-species transcriptome analyses for the regulation of crocins biosynthesis in Crocus. BMC Genomics 20:1.
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Biancamaria Senizza, Gabriele Rocchetti, Silvia Ghisoni, Matteo Busconi, Marcelino De Los Mozos Pascual, José Antonio Fernandez, Luigi Lucini & Marco Trevisan. (2019) Identification of phenolic markers for saffron authenticity and origin: An untargeted metabolomics approach. Food Research International 126, pages 108584.
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Mzabri, Addi & Berrichi. (2019) Traditional and Modern Uses of Saffron (Crocus Sativus). Cosmetics 6:4, pages 63.
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Mustapha Abba, Zaharah Ibrahim, Chun Shiong Chong, Nurliyana Ahmad Zawawi, Mohammed Rafiq Abdul Kadir, Abdul Halim Mohd Yusof & Saiful Izwan Abd Razak. (2019) Transdermal Delivery of Crocin Using Bacterial Nanocellulose Membrane. Fibers and Polymers 20:10, pages 2025-2031.
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Jamal Rahmani, Nicla Manzari, Jacqueline Thompson, Cain C.T. Clark, Gemma Villanueva, Hamed Kord Varkaneh & Parvin Mirmiran. (2019) The effect of saffron on weight and lipid profile: A systematic review, meta‐analysis, and dose–response of randomized clinical trials. Phytotherapy Research 33:9, pages 2244-2255.
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Roberto Consonni & Laura Ruth Cagliani. (2018) The potentiality of NMR‐based metabolomics in food science and food authentication assessment. Magnetic Resonance in Chemistry 57:9, pages 558-578.
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Elisabetta Esposito, Markus Drechsler, Carmelo Puglia & Rita Cortesi. (2019) New Strategies for the Delivery of Some Natural Anti-oxidants with Therapeutic Properties. Mini-Reviews in Medicinal Chemistry 19:13, pages 1030-1039.
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Eirini Christodoulou, Maria-Eleni Grafakou, Eleni Skaltsa, Nikolaos Kadoglou, Nikolaos Kostomitsopoulos & Georgia Valsami. (2019) Preparation, chemical characterization and determination of crocetin's pharmacokinetics after oral and intravenous administration of saffron ( Crocus sativus L.) aqueous extract to C57/BL6J mice . Journal of Pharmacy and Pharmacology 71:5, pages 753-764.
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Kyriaki Hatziagapiou, Eleni Kakouri, George I. Lambrou, Kostas Bethanis & Petros A. Tarantilis. (2019) Antioxidant Properties of Crocus Sativus L. and Its Constituents and Relevance to Neurodegenerative Diseases; Focus on Alzheimer’s and Parkinson’s Disease. Current Neuropharmacology 17:4, pages 377-402.
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Angelo Paolis, Giovanna Frugis, Donato Giannino, Maria Iannelli, Giovanni Mele, Eddo Rugini, Cristian Silvestri, Francesca Sparvoli, Giulio Testone, Maria Mauro, Chiara Nicolodi & Sofia Caretto. (2019) Plant Cellular and Molecular Biotechnology: Following Mariotti’s Steps. Plants 8:1, pages 18.
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Makan Pourmasoumi, Amir Hadi, Ameneh Najafgholizadeh, Marzieh Kafeshani & Amirhossein Sahebkar. (2019) Clinical evidence on the effects of saffron (Crocus sativus L.) on cardiovascular risk factors: A systematic review meta-analysis. Pharmacological Research 139, pages 348-359.
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Armin Amanpour, Hasim Kelebek & Serkan Selli. 2019. Bioactive Molecules in Food. Bioactive Molecules in Food 1987 2035 .
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Azar Moradi, Fateme Zarinkamar, Sofia Caretto & Pejman Azadi. (2018) Influence of thidiazuron on callus induction and crocin production in corm and style explants of Crocus sativus L.. Acta Physiologiae Plantarum 40:11.
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Evangelia Karkoula, Apostolis Angelis, Nikolaos‐Stavros Koulakiotis, Evangelos Gikas, Maria Halabalaki, Anthony Tsarbopoulos & Alexios‐Leandros Skaltsounis. (2018) Rapid isolation and characterization of crocins, picrocrocin, and crocetin from saffron using centrifugal partition chromatography and LC–MS. Journal of Separation Science 41:22, pages 4105-4114.
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Donatella Aiello, Carlo Siciliano, Fabio Mazzotti, Leonardo Di Donna, Constantinos M. Athanassopoulos & Anna Napoli. (2018) Molecular species fingerprinting and quantitative analysis of saffron ( Crocus sativus L.) for quality control by MALDI mass spectrometry . RSC Advances 8:63, pages 36104-36113.
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Fotini N. Lamari, Vassilis Papasotiropoulos, Dimitris Tsiris, Stavros E. Bariamis, Konstantinos Sotirakis, Efthimia Pitsi, Amalia P. Vogiatzoglou & Gregoris Iatrou. (2018) Phytochemical and genetic characterization of styles of wild Crocus species from the island of Crete, Greece and comparison to those of cultivated C. sativus. Fitoterapia 130, pages 225-233.
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Mahpara Kashtwari, Aijaz A. Wani, Manoj K. Dhar, Sabbi Jan & Azra N. Kamili. (2018) Development of an efficient in vitro mutagenesis protocol for genetic improvement of saffron (Crocus sativus L.). Physiology and Molecular Biology of Plants 24:5, pages 951-962.
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