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Original Articles

DITERPENES AND DITERPENE ESTERS IN COFFEE

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Pages 433-450 | Published online: 06 Feb 2007

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

Ahmed Mediani, Nurkhalida Kamal, Soo Yee Lee, Faridah Abas & Mohamed A. Farag. (2023) Green Extraction Methods for Isolation of Bioactive Substances from Coffee Seed and Spent. Separation & Purification Reviews 52:1, pages 24-42.
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M.A.E. Silva, A.L.M. Brand, F.J.M. Novaes & C.M Rezende. (2022) Cafestol, Kahweol and Their Acylated Derivatives: Antitumor Potential, Pharmacokinetics, and Chemopreventive Profile. Food Reviews International 0:0, pages 1-33.
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Yelin Zhang, Wahyu diono, Ratana Rujiravanit, Hideki Kanda & Motonobu Goto. (2022) Extraction of diterpenes from spent coffee grounds and encapsulation into polyvinylpyrrolidone particles using supercritical carbon dioxide. Separation Science and Technology 57:7, pages 1081-1096.
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Büşra Başar Gökcen & Nevin Şanlier. (2019) Coffee consumption and disease correlations. Critical Reviews in Food Science and Nutrition 59:2, pages 336-348.
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Tais A. L. Wagemaker, Patrícia M. B. G. Maia Campos, Ana Sofia Fernandes, Patrícia Rijo, Marisa Nicolai, Amílcar Roberto, Catarina Rosado, Catarina Reis, Luis M. Rodrigues, Cássia Regina Limonta Carvalho, Nilson Borlina Maia & Oliveiro Guerreiro Filho. (2016) Unsaponifiable matter from oil of green coffee beans: cosmetic properties and safety evaluation. Drug Development and Industrial Pharmacy 42:10, pages 1695-1699.
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Marzieh Moeenfard, José Avelino Silva, Nuno Borges, Alejandro Santos & Arminda Alves. (2015) Quantification of Diterpenes and Their Palmitate Esters in Coffee Brews by HPLC-DAD. International Journal of Food Properties 18:10, pages 2284-2299.
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Justyna Godos, Francesca Romana Pluchinotta, Stefano Marventano, Silvio Buscemi, Giovanni Li Volti, Fabio Galvano & Giuseppe Grosso. (2014) Coffee components and cardiovascular risk: beneficial and detrimental effects. International Journal of Food Sciences and Nutrition 65:8, pages 925-936.
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Articles from other publishers (73)

Giulia Strocchi, Anja B. Müller, Nikolai Kuhnert, Katia Martina, Carlo Bicchi & Erica Liberto. (2023) Diterpenes stability of commercial blends of roasted and ground coffees packed in copolymer coupled with aluminium and eco-friendly capsules. Food Research International 174, pages 113577.
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Fábio Junior Moreira Novaes, Maria Alice Esteves da Silva, Diana Cardoso Silva, Francisco Radler de Aquino Neto & Claudia Moraes Rezende. (2023) Extraction of Diterpene-Phytochemicals in Raw and Roasted Coffee Beans and Beverage Preparations and Their Relationship. Plants 12:8, pages 1580.
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Shady Awwad, Ahmed Abu-Zaiton, Reem Issa, Rana Said, Ahmad Sundookah, Maha Habash, Beisan Mohammad & Mahmoud Abu-Samak. (2023) The effect of excessive coffee consumption, in relation to diterpenes levels of medium-roasted coffee, on non-high-density lipoprotein cholesterol level in healthy men. Pharmacia 70:1, pages 49-59.
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Gulsun Akdemir Evrendilek. 2023. Value-Addition in Beverages through Enzyme Technology. Value-Addition in Beverages through Enzyme Technology 199 216 .
Guilin Hu, Ding Dong, Shuzong Du, Xingrong Peng, Mingkun Wu, Qiangqiang Shi, Kun Hu, Defu Hong, Xiaoyuan Wang, Lin Zhou, Yin Nian & Minghua Qiu. (2022) Discovery of novel coffee diterpenoids with inhibitions on Cav3.1 low voltage-gated Ca2+ channel. Food Chemistry 376, pages 131923.
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Fatma Hulyam Eren & Halit Tanju Besler. (2022) Bioactive diterpenes (cafestol and kahweol) in Turkish coffees: Impact of roasting. International Food Research Journal 29:2, pages 328-337.
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Hanjing Wu, Jingyu Gu, Amrit BK, Malik A. Nawaz, Colin J. Barrow, Frank R. Dunshea & Hafiz A.R. Suleria. (2022) Effect of processing on bioaccessibility and bioavailability of bioactive compounds in coffee beans. Food Bioscience 46, pages 101373.
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Melissa García-Caballero, José Antonio Torres-Vargas, Ana Dácil Marrero, Beatriz Martínez-Poveda, Miguel Ángel Medina & Ana R. Quesada. (2022) Angioprevention of Urologic Cancers by Plant-Derived Foods. Pharmaceutics 14:2, pages 256.
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De-Fu Hong, Gui-Lin Hu, Xing-Rong Peng, Xiao-Yuan Wang, Yan-Bing Wang, Abdulbaset Al-Romaima, Zhong-Rong Li & Ming-Hua Qiu. (2022) Unusual ent -Kaurane Diterpenes from the Coffea Cultivar S288 Coffee Beans and Molecular Docking to α-Glucosidase . Journal of Agricultural and Food Chemistry 70:2, pages 615-625.
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Liliana Sofia da Silva Gache, Josiana Vaz & Juliana Almeida-de-Souza. (2021) Systematic Review of the Effects of Coffee or Its Components on Platelets and Their Regulators. Journal of Caffeine and Adenosine Research 11:3, pages 51-64.
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Büşra Açıkalın & Nevin Sanlier. (2021) Coffee and its effects on the immune system. Trends in Food Science & Technology 114, pages 625-632.
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Yoshinori Asakawa & Hiromichi Kenmoku. 2021. Handbook of Dietary Phytochemicals. Handbook of Dietary Phytochemicals 733 927 .
Yoshinori Asakawa & Hiromichi Kenmoku. 2020. Handbook of Dietary Phytochemicals. Handbook of Dietary Phytochemicals 1 195 .
Ju-Chi Liu, Po-Yuan Chen, Wen-Rui Hao, Yi-Chung Liu, Ping-Chiang Lyu & Hong-Jye Hong. (2020) Cafestol Inhibits High-Glucose-Induced Cardiac Fibrosis in Cardiac Fibroblasts and Type 1-Like Diabetic Rats. Evidence-Based Complementary and Alternative Medicine 2020, pages 1-11.
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Vincent Portaluri, Freddy Thomas, Sophie Guyader, Eric Jamin, Benoit Bertrand, Gérald S. Remaud, Elisabetta Schievano, Stefano Mammi, Elena Guercia & Luciano Navarini. (2020) Limited genotypic and geographic variability of 16-O-methylated diterpene content in Coffea arabica green beans. Food Chemistry 329, pages 127129.
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Fábio Junior Moreira Novaes, Fernanda Alves Lima, Verônica Calado, Philip John Marriott, Francisco Radler de Aquino Neto & Claudia Moraes Rezende. (2020) Isolating valuable coffee diterpenes by using an inexpensive procedure. Industrial Crops and Products 152, pages 112494.
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Elena Guercia, Silvia Colomban & Luciano Navarini. (2020) 16- O -Methylated diterpenes in green Coffea arabica : ultra-high-performance liquid chromatography-tandem mass spectrometry method optimization and validation . Journal of Mass Spectrometry, pages e4636.
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Sabur Badmos, Maotian Fu, Daniel Granato & Nikolai Kuhnert. (2020) Classification of Brazilian roasted coffees from different geographical origins and farming practices based on chlorogenic acid profiles. Food Research International 134, pages 109218.
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Marzieh Moeenfard & Arminda Alves. (2020) New trends in coffee diterpenes research from technological to health aspects. Food Research International 134, pages 109207.
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José P. Coelho, Rui M. Filipe, M. Paula Robalo, Stanislava Boyadzhieva, Georgi St. Cholakov & Roumiana P. Stateva. (2020) Supercritical CO2 extraction of spent coffee grounds. Influence of co-solvents and characterization of the extracts. The Journal of Supercritical Fluids 161, pages 104825.
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Marzieh Moeenfard, Guillaume L. Erny & Arminda Alves. (2020) Determination of diterpene esters in green and roasted coffees using direct ultrasound assisted extraction and HPLC–DAD combined with spectral deconvolution. Journal of Food Measurement and Characterization 14:3, pages 1451-1460.
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Josephin Giacomini, Gulzhan Khamitova, Pierluigi Maponi, Sauro Vittori & Lauro Fioretti. (2020) Water flow and transport in porous media for in-silico espresso coffee. International Journal of Multiphase Flow 126, pages 103252.
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Rodolfo Campos Zanin, Cíntia Sorane Good Kitzberger & Marta de Toledo Benassi. (2020) Characterization of Roasted Coffea arabica Species by the Relationship Between Caffeine and Diterpenes Contents. Brazilian Archives of Biology and Technology 63.
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Mirelli Bianchin, Hugo Henrique Carline de Lima, Alessandra Maffei Monteiro & Marta de Toledo Benassi. (2020) Optimization of ultrasonic-assisted extraction of kahweol and cafestol from roasted coffee using response surface methodology. LWT 117, pages 108593.
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Ahmed A. Hussein. 2020. Cold Pressed Oils. Cold Pressed Oils 703 710 .
Xia Wang, Xingrong Peng, Jing Lu, Guilin Hu & Minghua Qiu. (2019) Ent-kaurane diterpenoids from the cherries of Coffea arabica. Fitoterapia 132, pages 7-11.
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Xia Wang, QianQian Meng, XingRong Peng, GuiLin Hu & MingHua Qiu. (2018) Identification of new diterpene esters from green Arabica coffee beans, and their platelet aggregation accelerating activities. Food Chemistry 263, pages 251-257.
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Fábio Junior Moreira Novaes, Ivaldo Itabaiana Junior, Felipe Korbus Sutili, Philip John Marriott, Humberto Ribeiro Bizzo, Francisco Radler de Aquino Neto, Rodrigo Octávio Mendonça Alves de Souza & Claudia Moraes Rezende. (2018) Lipase-catalysed esters synthesis of cafestol and kahweol. Food Chemistry 259, pages 226-233.
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Yvonne Gunning, Marianne Defernez, Andrew D. Watson, Niles Beadman, Ian J. Colquhoun, Gwénaëlle Le Gall, Mark Philo, Hollie Garwood, David Williamson, Aaron P. Davis & E. Kate Kemsley. (2018) 16-O-methylcafestol is present in ground roast Arabica coffees: Implications for authenticity testing. Food Chemistry 248, pages 52-60.
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Yi-Ting Tsai, Li-Chin Sung, Wen-Ray Haw, Chun-Chao Chen, Shu-Fu Huang, Ju-Chi Liu, Tzu-Hurng Cheng, Po-Yuan Chen, Shih-Hurng Loh & Chien-Sung Tsai. (2018) Cafestol, a coffee diterpene, inhibits urotensin II-induced interleukin-8 expression in human umbilical vein endothelial cells. European Journal of Pharmacology 820, pages 106-112.
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Wen-Rui Hao, Li-Chin Sung, Chun-Chao Chen, Po-Yuan Chen, Tzu-Hurng Cheng, Hung-Hsing Chao, Ju-Chi Liu & Jin-Jer Chen. (2018) Cafestol Inhibits Cyclic-Strain-Induced Interleukin-8, Intercellular Adhesion Molecule-1, and Monocyte Chemoattractant Protein-1 Production in Vascular Endothelial Cells. Oxidative Medicine and Cellular Longevity 2018, pages 1-10.
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Claudia Oellig & Jessica Radovanovic. (2017) Screening for 16- O -methylcafestol in roasted coffee by high-performance thin-layer chromatography–fluorescence detection – Determination of Coffea canephora admixtures to Coffea arabica. Journal of Chromatography A 1525, pages 173-180.
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Marianne Defernez, Ella Wren, Andrew D. Watson, Yvonne Gunning, Ian J. Colquhoun, Gwénaëlle Le Gall, David Williamson & E. Kate Kemsley. (2017) Low-field 1H NMR spectroscopy for distinguishing between arabica and robusta ground roast coffees. Food Chemistry 216, pages 106-113.
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B. Baspinar, G. Eskici & A. O. Ozcelik. (2017) How coffee affects metabolic syndrome and its components. Food & Function 8:6, pages 2089-2101.
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Marzieh Moeenfard, Alice Cortez, Vera Machado, Raquel Costa, Carla Luís, Pedro Coelho, Raquel Soares, Arminda Alves, Nuno Borges & Alejandro Santos. (2016) Anti-Angiogenic Properties of Cafestol and Kahweol Palmitate Diterpene Esters. Journal of Cellular Biochemistry 117:12, pages 2748-2756.
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Bing Cheng, Agnelo Furtado, Heather E. Smyth & Robert J. Henry. (2016) Influence of genotype and environment on coffee quality. Trends in Food Science & Technology 57, pages 20-30.
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Marzieh Moeenfard, Guillaume L. Erny & Arminda Alves. (2016) Variability of some diterpene esters in coffee beverages as influenced by brewing procedures. Journal of Food Science and Technology 53:11, pages 3916-3927.
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Veronica Belandria, Paola Maressa Aparecida de Oliveira, Agnes Chartier, José A. Rabi, Alessandra Lopes de Oliveira & Stephane Bostyn. (2016) Pressurized-fluid extraction of cafestol and kahweol diterpenes from green coffee. Innovative Food Science & Emerging Technologies 37, pages 145-152.
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Rui Chu, Luo-Sheng Wan, Xing-Rong Peng, Mu-Yuan Yu, Zhi-Run Zhang, Lin Zhou, Zhong-Rong Li & Ming-Hua Qiu. (2016) Characterization of New Ent-kaurane Diterpenoids of Yunnan Arabica Coffee Beans. Natural Products and Bioprospecting 6:4, pages 217-223.
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Hendryk Czech, Claudia Schepler, Sophie Klingbeil, Sven Ehlert, Jessalin Howell & Ralf Zimmermann. (2016) Resolving Coffee Roasting-Degree Phases Based on the Analysis of Volatile Compounds in the Roasting Off-Gas by Photoionization Time-of-Flight Mass Spectrometry (PI-TOFMS) and Statistical Data Analysis: Toward a PI-TOFMS Roasting Model. Journal of Agricultural and Food Chemistry 64:25, pages 5223-5231.
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V. Sridevi & P. Giridhar. (2015) Variations in Diterpenes-Cafestol and Kahweol Content in Beans of Robusta Coffee Grown at Different Altitudes. Proceedings of the National Academy of Sciences, India Section B: Biological Sciences 86:2, pages 291-297.
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Fábio Junior Moreira Novaes, Silvia Siag Oigman, Rodrigo Octavio Mendonça Alves de Souza, Claudia Moraes Rezende & Francisco Radler de Aquino Neto. (2015) New approaches on the analyses of thermolabile coffee diterpenes by gas chromatography and its relationship with cup quality. Talanta 139, pages 159-166.
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Guillaume L. Erny, Marzieh Moeenfard & Arminda Alves. (2015) Liquid chromatography with diode array detection combined with spectral deconvolution for the analysis of some diterpene esters in Arabica coffee brew. Journal of Separation Science 38:4, pages 612-620.
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Marta de Toledo Benassi & Rafael Carlos Eloy Dias. 2015. Coffee in Health and Disease Prevention. Coffee in Health and Disease Prevention 993 1004 .
Xiuju Wang & Loong-Tak Lim. 2015. Coffee in Health and Disease Prevention. Coffee in Health and Disease Prevention 247 254 .
Deborah Pacetti, Paolo Lucci & Natale G. Frega. 2015. Coffee in Health and Disease Prevention. Coffee in Health and Disease Prevention 119 127 .
Rafael Carlos Eloy Dias, Adelia Ferreira de Faria-Machado, Adriana Zerlotti Mercadante, Neura Bragagnolo & Marta de Toledo Benassi. (2014) Roasting process affects the profile of diterpenes in coffee. European Food Research and Technology 239:6, pages 961-970.
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Vaddadi Sridevi & Parvatam Giridhar. (2014) Establishment of somaclonal variants of Robusta coffee with reduced levels of cafestol and kahweol. In Vitro Cellular & Developmental Biology - Plant 50:5, pages 618-626.
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M.B.S. Scholz, N.F. Pagiatto, C.S.G. Kitzberger, L.F.P. Pereira, F. Davrieux, P. Charmetant & T. Leroy. (2014) Validation of near-infrared spectroscopy for the quantification of cafestol and kahweol in green coffee. Food Research International 61, pages 176-182.
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Yi Shu, Jie-Qing Liu, Xing-Rong Peng, Luo-Sheng Wan, Lin Zhou, Tao Zhang & Ming-hua Qiu. (2014) Characterization of Diterpenoid Glucosides in Roasted Puer Coffee Beans. Journal of Agricultural and Food Chemistry 62:12, pages 2631-2637.
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Iziar A. Ludwig, Michael N. Clifford, Michael E. J. Lean, Hiroshi Ashihara & Alan Crozier. (2014) Coffee: biochemistry and potential impact on health. Food Funct. 5:8, pages 1695-1717.
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Hugo M.A. Barbosa, Marcelo M.R. de Melo, Manuel A. Coimbra, Cláudia P. Passos & Carlos M. Silva. (2014) Optimization of the supercritical fluid coextraction of oil and diterpenes from spent coffee grounds using experimental design and response surface methodology. The Journal of Supercritical Fluids 85, pages 165-172.
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Draženka Komes & Ana Belščak-Cvitanović. 2014. Processing and Impact on Antioxidants in Beverages. Processing and Impact on Antioxidants in Beverages 87 97 .
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Agnes Chartier, Mathieu Beaumesnil, Alessandra Lopes de Oliveira, Claire Elfakir & Stephane Bostyn. (2013) Optimization of the isolation and quantitation of kahweol and cafestol in green coffee oil. Talanta 117, pages 102-111.
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Cíntia Sorane Good Kitzberger, Maria Brígida dos Santos Scholz, Luiz Filipe Protasio Pereira & Marta de Toledo Benassi. (2013) Composição química de cafés árabica de cultivares tradicionais e modernas. Pesquisa Agropecuária Brasileira 48:11, pages 1498-1506.
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Romy Hertz-Schünemann, Thorsten Streibel, Sven Ehlert & Ralf Zimmermann. (2013) Looking into individual coffee beans during the roasting process: direct micro-probe sampling on-line photo-ionisation mass spectrometric analysis of coffee roasting gases. Analytical and Bioanalytical Chemistry 405:22, pages 7083-7096.
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Rafael Carlos Eloy Dias, Sandriel Trindade Alves & Marta de Toledo Benassi. (2013) Spectrophotometric method for quantification of kahweol in coffee. Journal of Food Composition and Analysis 31:1, pages 137-143.
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Cíntia Sorane Good Kitzberger, Maria Brígida dos Santos Scholz, Luiz Filipe Protasio Pereira, Luiz Gonzaga Esteves Vieira, Tumoru Sera, João Batista Gonçalves Dias Silva & Marta de Toledo Benassi. (2013) Diterpenes in green and roasted coffee of Coffea arabica cultivars growing in the same edapho-climatic conditions. Journal of Food Composition and Analysis 30:1, pages 52-57.
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José A. Silva, Nuno Borges, Alejandro Santos & Arminda Alves. (2012) Method Validation for Cafestol and Kahweol Quantification in Coffee Brews by HPLC-DAD. Food Analytical Methods 5:6, pages 1404-1410.
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Chen Zhang, Robert Linforth & Ian D. Fisk. (2012) Cafestol extraction yield from different coffee brew mechanisms. Food Research International 49:1, pages 27-31.
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Rafael Garrett, Boniek G. Vaz, Ana Maria C. Hovell, Marcos N. Eberlin & Claudia M. Rezende. (2012) Arabica and Robusta Coffees: Identification of Major Polar Compounds and Quantification of Blends by Direct-Infusion Electrospray Ionization–Mass Spectrometry. Journal of Agricultural and Food Chemistry 60:17, pages 4253-4258.
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Anke Keidel, David von Stetten, Carla Rodrigues, Cristina Máguas & Peter Hildebrandt. (2010) Discrimination of Green Arabica and Robusta Coffee Beans by Raman Spectroscopy. Journal of Agricultural and Food Chemistry 58:21, pages 11187-11192.
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Rafael Carlos Eloy Dias, Fernanda Gonçalves Campanha, Luiz Gonzaga Esteves Vieira, Lucia Pires Ferreira, David Pot, Pierre Marraccini & Marta De Toledo Benassi. (2009) Evaluation of Kahweol and Cafestol in Coffee Tissues and Roasted Coffee by a New High-Performance Liquid Chromatography Methodology. Journal of Agricultural and Food Chemistry 58:1, pages 88-93.
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Maria De Lucia, Lucia Panzella, Dominique Melck, Italo Giudicianni, Andrea Motta, Alessandra Napolitano & Marco d’Ischia. (2009) Differential Reactivity of Purified Bioactive Coffee Furans, Cafestol and Kahweol, with Acidic Nitrite: Product Characterization and Factors Controlling Nitrosation Versus Ring-Opening Pathways. Chemical Research in Toxicology 22:12, pages 1922-1928.
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Heike Scharnhop & Peter Winterhalter. (2009) Isolation of coffee diterpenes by means of high-speed countercurrent chromatography. Journal of Food Composition and Analysis 22:3, pages 233-237.
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Karl Speer & Isabelle Kölling-Speer. (2006) The lipid fraction of the coffee bean. Brazilian Journal of Plant Physiology 18:1, pages 201-216.
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Aloys B. Rubayiza & Marc Meurens. (2005) Chemical Discrimination of Arabica and Robusta Coffees by Fourier Transform Raman Spectroscopy. Journal of Agricultural and Food Chemistry 53:12, pages 4654-4659.
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S. Bee, C.H.J. Brando, G. Brumen, N. Carvalhaes, I. Kölling-Speer, K. Speer, F. Suggi Liverani, A.A. Teixeira, R. Teixeira, R.A. Thomaziello, R. Viani & O.G. Vitzthum. 2005. Espresso Coffee. Espresso Coffee 87 178 .
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Gonzalo Chiriboga, Sophía Peñaherrera, Pablo Londoño-Larrea, Luis Castillo, Carolina Montero & Ghem Carvajal C. (2022) The Effect of the Chemical Composition on the Sensory Characterization of Ecuadorian Coffee. SSRN Electronic Journal.
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