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Original Articles

Spiral Disk Assembly for HSCCC: Column Design and Basic Studies on Chromatographic Resolution and Stationary Phase Retention

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Pages 1355-1372 | Received 25 Jun 2002, Accepted 12 Dec 2002, Published online: 06 Feb 2007

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (11)

Tao Chen, Yongling Liu, Shuo Wang, Yangfei Wei, Zhibo Song, Shuping Yan, Cheng Shen, Hongmei Li, Peipei Li & Yulin Li. (2022) Separation of eight phenolic compounds from the over-ground parts of Aconitum pendulum Busch by repeated injection high-speed counter-current chromatography. Separation Science and Technology 57:10, pages 1585-1594.
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Zhicong Liu, Yongjie Zhao, Huihui Peng, Tiexuan Luo & Yang Liu. (2022) Countercurrent chromatography: separation principle, mechanical design, development trends, and applications. Journal of Liquid Chromatography & Related Technologies 45:5-8, pages 51-65.
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KoreyJ. Brownstein, Martha Knight, Yoichiro Ito, GeorgeE. Rottinghaus & WilliamR. Folk. (2015) Isolation of the Predominant Cycloartane Glycoside, Sutherlandioside B, from Sutherlandia frutescens (L.) R.Br. by Spiral Countercurrent Chromatography. Journal of Liquid Chromatography & Related Technologies 38:4, pages 423-429.
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Lianhong Yin, Yingnan Li, Binan Lu, Yujie Jia & Jinyong Peng. (2010) Trends in Counter-Current Chromatography: Applications to Natural Products Purification. Separation & Purification Reviews 39:1-2, pages 33-62.
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Martha Knight & ThomasM. Finn. (2009) Spiral Countercurrent Chromatography Studies Using the Spiral Disk Assembly. Journal of Liquid Chromatography & Related Technologies 32:18, pages 2669-2685.
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Y. Ito, R. Clary, J. Powell, M. Knight & T. M. Finn. (2009) Spiral Tube Assembly for High-Speed Countercurrent Chromatography: Choice of Elution Modes for Four Typical Two-Phase Solvent Systems. Journal of Liquid Chromatography & Related Technologies 32:14, pages 2013-2029.
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Y. Ito, R. Clary, J. Powell, M. Knight & T. M. Finn. (2008) Spiral Tube Support for High‐Speed Countercurrent Chromatography. Journal of Liquid Chromatography & Related Technologies 31:9, pages 1346-1357.
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Martha Knight, Yoichiro Ito & Thomas M. Finn. (2008) Separation of Peptides by Spiral Countercurrent Chromatography. Journal of Liquid Chromatography & Related Technologies 31:4, pages 471-481.
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I. Al‐Marzouqi, M. S. Levy & G. J. Lye. (2005) Hydrodynamics of PEG‐Phosphate Aqueous Two‐Phase Systems in a J‐Type Multilayer Countercurrent Chromatograph. Journal of Liquid Chromatography & Related Technologies 28:9, pages 1311-1332.
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Nils Köhler, Edward Chou, Yoichiro Ito & Peter Winterhalter. (2004) Development of a New Preparative Spiral‐Coil Low‐Speed Rotary Countercurrent Chromatographic (Spiral‐Coil LSRCCC) Method. Journal of Liquid Chromatography & Related Technologies 27:16, pages 2547-2560.
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Yoichi Shibusawa, Mitsuhiro Isozaki, Akio Yanagida, Heisaburo Shindo & Yoichiro Ito. (2004) Purification of Glucosyltransferase from Streptococcus sobrinus Cell Culture Medium by Combined Use of Batch Extraction and Countercurrent Chromatography with a Polymer Phase System. Journal of Liquid Chromatography & Related Technologies 27:14, pages 2217-2234.
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Articles from other publishers (31)

Shunjie Zhang, Haijun Chen, Xiaodie Deng, Hailu Chen, Chanjuan Guo, Li Wan, Aihua Peng & Lijuan Chen. (2021) Advantages of rectangular horizontal tubing in the semi-preparative counter-current chromatography bobbin. Journal of Chromatography A 1657, pages 462583.
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Lihong Zhang & Shihua Wu. (2020) Hydrophobic and hydrophilic interactions in countercurrent chromatography. Journal of Chromatography A 1611, pages 460576.
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Vicky Lange, Leslie Brown & Panagiota Angeli. (2018) Hydrodynamics studies of the behaviour of traditional and two-phase ionic liquid solvent systems in countercurrent chromatography (CCC). Chemical Engineering Science 192, pages 551-564.
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Lihong Zhang, Yanyan Wang, Xiuyun Guo & Shihua Wu. (2017) Concentrical coils counter-current chromatography for natural products isolation: Salvia miltiorrhiza Bunge as example. Journal of Chromatography A 1491, pages 108-116.
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Xin-Yi Huang, Xiao-Ming Sun, Dong Pei & Duo-Long Di. (2017) Spiral counter-current chromatography: Design, development, application, and challenges. Journal of Separation Science 40:1, pages 336-345.
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Weili Li & Tao Wu. (2016) Rapid separation of polysaccharides using a novel spiral coil column by high-speed countercurrent chromatography. Journal of Separation Science 39:8, pages 1404-1410.
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Xiaofeng Ma & Yoichiro Ito. (2015) New analytical spiral tube assembly for separation of proteins by counter-current chromatography. Journal of Chromatography A 1405, pages 193-196.
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Kazufusa Shinomiya, Koji Tokura, Emiru Kimura, Midori Takai, Naoki Harikai, Kazunori Yoshida, Kazuhiro Yanagidaira & Yoichiro Ito. (2015) Design of a coil satellite centrifuge and its performance on counter-current chromatographic separation of 4-methylumbelliferyl sugar derivatives with polar organic–aqueous two-phase solvent systems. Journal of Chromatography A 1392, pages 48-55.
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Adrian Weisz, Clark D. Ridge, Eugene P. Mazzola & Yoichiro Ito. (2015) Preparative separation and identification of novel subsidiary colors of the color additive D&C Red No. 33 (Acid Red 33) using spiral high-speed counter-current chromatography. Journal of Chromatography A 1380, pages 120-129.
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Jie Meng, Zhi Yang, Junling Liang, Mengze Guo & Shihua Wu. (2014) Multi-channel recycling counter-current chromatography for natural product isolation: Tanshinones as examples. Journal of Chromatography A 1327, pages 27-38.
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Yoichiro Ito, Martha Knight & Thomas M. Finn. (2013) Spiral Countercurrent Chromatography. Journal of Chromatographic Science 51:7, pages 726-738.
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Junling Liang, Jie Meng, Mengzhe Guo, Zhi Yang & Shihua Wu. (2013) Conical coils counter-current chromatography for preparative isolation and purification of tanshinones from Salvia miltiorrhiza Bunge. Journal of Chromatography A 1288, pages 35-39.
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Ruilin Hu & Yuanjiang Pan. (2012) Recent trends in counter-current chromatography. TrAC Trends in Analytical Chemistry 40, pages 15-27.
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Yue Hugh Guan, Remco N.A.M. van den Heuvel & Ying-Ping Zhuang. (2012) Visualisation of J-type counter-current chromatography: A route to understand hydrodynamic phase distribution and retention. Journal of Chromatography A 1239, pages 10-21.
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Susanne Baldermann, Andriati N. Mulyadi, Ziyin Yang, Ariaka Murata, Peter Fleischmann, Peter Winterhalter, Martha Knight, Thomas M. Finn & Naoharu Watanabe. (2011) Application of centrifugal precipitation chromatography and high‐speed counter‐current chromatography equipped with a spiral tubing support rotor for the isolation and partial characterization of carotenoid cleavage‐like enzymes in Enteromorpha compressa (L.) Nees . Journal of Separation Science 34:19, pages 2759-2764.
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Xueli Cao, Hairun Pei, Liangsheng Huo, Guanghui Hu & Yoichiro Ito. (2011) Development and evaluation of a spiral tube column for counter‐current chromatography. Journal of Separation Science 34:19, pages 2611-2617.
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Martha Knight, Thomas M. Finn, John Zehmer, Adam Clayton & Aprile Pilon. (2011) Spiral counter-current chromatography of small molecules, peptides and proteins using the spiral tubing support rotor. Journal of Chromatography A 1218:36, pages 6148-6155.
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Yoichiro Ito. (2010) Spiral column configuration for protein separation by high-speed countercurrent chromatography. Chemical Engineering and Processing: Process Intensification 49:7, pages 782-792.
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Yi Yang, Haji Akber Aisa & Yoichiro Ito. (2009) Flat-twisted tubing: Novel column design for spiral high-speed counter-current chromatography. Journal of Chromatography A 1216:27, pages 5265-5271.
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Y. Ito, R. Clary, J. Powell, M. Knight & T.M. Finn. (2009) Improved spiral tube assembly for high-speed counter-current chromatography. Journal of Chromatography A 1216:19, pages 4193-4200.
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Guido F. Pauli, Samuel M. Pro & J. Brent Friesen. (2008) Countercurrent Separation of Natural Products. Journal of Natural Products 71:8, pages 1489-1508.
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Xueli Cao, Guanghui Hu, Liangsheng Huo, Xiaoping Zhu, Ting Li, Jimmie Powell & Yoichiro Ito. (2008) Stationary phase retention and preliminary application of a spiral disk assembly designed for high-speed counter-current chromatography. Journal of Chromatography A 1188:2, pages 164-170.
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Shihua Wu, Lu Yang, Yuan Gao, Xiaoyue Liu & Feiyan Liu. (2008) Multi-channel counter-current chromatography for high-throughput fractionation of natural products for drug discovery. Journal of Chromatography A 1180:1-2, pages 99-107.
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Yoichiro Ito, Robert Clary, Frank Sharpnak, Howard Metger & Jimmie Powell. (2007) Mixer-settler counter-current chromatography with multiple spiral disk assembly. Journal of Chromatography A 1172:2, pages 151-159.
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Kazufusa Shinomiya, Hiroko Kobayashi, Norio Inokuchi, Koji Kobayashi, Hisashi Oshima, Susumu Kitanaka, Kazuhiro Yanagidaira, Haruo Sasaki, Minoru Muto, Michiharu Okano & Yoichiro Ito. (2007) New small-scale cross-axis coil planet centrifuge. Journal of Chromatography A 1151:1-2, pages 91-98.
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Martha Knight. (2007) Separations of hydrophobic synthetic peptides in counter-current chromatography. Journal of Chromatography A 1151:1-2, pages 148-152.
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Y.H. Guan, J. Smulders, D. Fisher & I.A. Sutherland. (2007) Spiral coils for counter-current chromatography using aqueous polymer two-phase systems. Journal of Chromatography A 1151:1-2, pages 115-120.
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Yoichiro Ito, Lin Qi, Jimmie Powell, Frank Sharpnack, Howard Metger, James Yost, Xue-Li Cao, Yin-Mao Dong, Liang-Sheng Huo, Xiao-Ping Zhu & Ting Li. (2007) Mixer-settler counter-current chromatography with a barricaded spiral disk assembly with glass beads. Journal of Chromatography A 1151:1-2, pages 108-114.
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Wenbo Zhi, Qiuyun Deng, Jiangnan Song, Ming Gu & Fan Ouyang. (2005) One-step purification of α-amylase from the cultivation supernatant of recombinant Bacillus subtilis by high-speed counter-current chromatography with aqueous polymer two-phase systems. Journal of Chromatography A 1070:1-2, pages 215-219.
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Yoichi Shibusawa, Takiko Fujiwara, Heisaburo Shindo & Yoichiro Ito. (2004) Purification of alcohol dehydrogenase from bovine liver crude extract by dye–ligand affinity counter-current chromatography. Journal of Chromatography B 799:2, pages 239-244.
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Yoichiro Ito, Fuquan Yang, Paul Fitze, Jimmie Powell & David Ide. (2003) Improved spiral disk assembly for high-speed counter-current chromatography. Journal of Chromatography A 1017:1-2, pages 71-81.
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