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Original Articles

Simultaneous Analysis of Candesartan Cilexetil and Hydrochlorothiazide in Human Plasma and Dosage Forms Using HPLC with a Photodiode Array Detector

Pages 2581-2591 | Received 10 Feb 2003, Accepted 09 Apr 2003, Published online: 06 Feb 2007

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Read on this site (2)

Rakshit Thakkar, Hitesh Saravaia & Anamik Shah. (2015) Determination of Antipsychotic Drugs Known for Narcotic Action by Ultra Performance Liquid Chromatography. Analytical Chemistry Letters 5:1, pages 1-11.
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Naseem Ahmad Charoo, Mohammad Bashir, Enas Abdalla & Khalid Ibrahim Haj Ali. (2009) Determination of Candesartan Cilexetil in Tablet Dosage Forms and Dissolution Testing Samples by First Derivative UV Spectrophotometric Method. Analytical Letters 42:14, pages 2232-2243.
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Articles from other publishers (20)

Mahmoud A. Mohamed & Hossam F. Nassar. (2023) Stability-indicating RP-UPLC method for determination of antihypertensive drugs and their degradation products in tablets: application to content uniformity and dissolution studies. Journal of the Iranian Chemical Society 20:4, pages 763-773.
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Diyar Salahuddin Ali. (2023) Chemometric Methods for Simultaneous Determination of Candesartan Cilexetil and Hydrochlorothiazide in Binary Combinations. Journal of Analytical Methods in Chemistry 2023, pages 1-14.
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Sara El-Hanboushy, Hoda M. Marzouk, Yasmin M. Fayez, Mohamed Abdelkawy & Hayam M. Lotfy. (2022) Sustainable spectrophotometric determination of antihypertensive medicines reducing COVID-19 risk via paired wavelength data processing technique - Assessment of purity, greenness and whiteness. Sustainable Chemistry and Pharmacy 29, pages 100806.
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P. K. Karnakova, T. N. Komarov, O. A. Archakova, D. S. Shchelgacheva, A. A. Aleshina, N. S. Bagaeva, P. A. Karpova & I. E. Shohin. (2021) Simultaneous Determination of Candesartan and Hydrochlorothiazide in Human Plasma by HPLC-MS/MS. Drug development & registration 10:4, pages 177-189.
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Khaled AboulFotouh, Ayat A. Allam, Mahmoud El-Badry & Ahmed M. El-Sayed. (2019) A Self-Nanoemulsifying Drug Delivery System for Enhancing the Oral Bioavailability of Candesartan Cilexetil: Ex Vivo and In Vivo Evaluation. Journal of Pharmaceutical Sciences 108:11, pages 3599-3608.
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Marta de Diego, Ricardo Godoy, Sigrid Mennickent, Carola Vergara, Daniel Miranda & Pía Navarro. (2018) Stability-Indicating Liquid Chromatographic Methods with Photodiode Array Detection and Light Scattering Detection for Simultaneous Determination of Candesartan and Hydrochlorothiazide. Journal of Chromatographic Science 56:2, pages 99-107.
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Bhargav Patel, Arvind G. Jangid, B.N. Suhagia & Nirmal Desai. (2017) The simultaneous UPLC-MS/MS determination of emerging drug combination; candesartan and chlorthalidone in human plasma and its application. Biomedical Chromatography 31:9, pages e3946.
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Mukthinuthalapati Mathrusri Annapurna. (2017) Quality by Design Approach (QbD) for the Simultaneous Determination of Anti-Hypertensive Drugs (Candesartan, Irbesartan and Hydrochlorothiazide) by RP-HPLC. Journal of Analytical & Pharmaceutical Research 4:5.
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Maha Abdel Monem Hegazy & Yasmin Mohammed Fayez. (2015) Mean centering of ratio spectra and concentration augmented classical least squares in a comparative approach for quantitation of spectrally overlapped bands of antihypertensives in formulations. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 140, pages 210-215.
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Izabela Muszalska, Agnieszka Sobczak, Agnieszka Dołhań & Anna Jelińska. (2014) Analysis of Sartans: A Review. Journal of Pharmaceutical Sciences 103:1, pages 2-28.
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Tarek S. Belal, Hoda G. Daabees, Magdi M. Abdel-Khalek, Mohamed S. Mahrous & Mona M. Khamis. (2013) New simple spectrophotometric method for determination of the binary mixtures (atorvastatin calcium and ezetimibe; candesartan cilexetil and hydrochlorothiazide) in tablets. Journal of Pharmaceutical Analysis 3:2, pages 118-126.
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D Vijaya BharathiKishore Kumar Hotha, Pankaj K Chatki, V Satyanarayana & V Venkateswarlu. (2012) LC–MS/MS method for simultaneous estimation of candesartan and hydrochlorothiazide in human plasma and its use in clinical pharmacokinetics. Bioanalysis 4:10, pages 1195-1204.
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Gunda Srinivas, Kakumani Kishore Kumar, Gangaram V. Kanumula, M. Vishnu Priya & K. Mukkanti. (2012) A Stability Indicating UPLC Method for Candesartan in Bulk Drug Samples. American Journal of Analytical Chemistry 03:10, pages 704-709.
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Febry Ardiana, Maria L.A.D. Lestari & Gunawan Indrayanto. 2012. 79 112 .
Shailesh T. Prajapati, Pratik K. Patel, Vijendra B. Chauhan, Chhaganbhai N. Patel & Marmik Patel. (2011) Development and validation of the liquid chromatography-tandem mass spectrometry method for quantitative estimation of candesartan from human plasma. Pharmaceutical Methods 2:2, pages 130-134.
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Bahia Moussa, Marwa Mohamed & Nadia Youssef. (2011) Simultaneous densitometric TLC analysis of olmesartan medoxomil and hydrochlorothiazide in the tablet dosage form. Journal of Planar Chromatography – Modern TLC 24:1, pages 35-39.
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Lara F. Tutunji, Maha F. Tutunji, Mamoun I. Alzoubi, Manal H. Khabbas & Adi I. Arida. (2010) Simultaneous determination of irbesartan and hydrochlorothiazide in human plasma using HPLC coupled with tandem mass spectrometry: Application to bioequivalence studies. Journal of Pharmaceutical and Biomedical Analysis 51:4, pages 985-990.
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İncilay Süslü, Nuran Özaltın & Sacide Altınöz. (2009) Square-wave adsorptive stripping voltammetric determination of candesartan cilexetil in pharmaceutical formulations. Journal of Applied Electrochemistry 39:9, pages 1535-1543.
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Bipin Mehta & Sachin Morge. (2008) HPTLC-densitometric analysis of candesartan cilexetil and hydrochlorothiazide in tablets. Journal of Planar Chromatography – Modern TLC 21:3, pages 173-176.
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J.A. Murillo Pulgarı́n, A. Alañón Molina & G. Pérez-Olivares Nieto. (2004) Determination of hydrochlorothiazide in pharmaceutical preparations by time resolved chemiluminescence. Analytica Chimica Acta 518:1-2, pages 37-43.
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