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Nucleosides, Nucleotides & Nucleic Acids Volume 21, 2002 - Issue 3
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Original Articles

SYNTHESIS, ANTIVIRAL AND CYTOSTATIC ACTIVITIES, OF CARBOCYCLIC NUCLEOSIDES INCORPORATING A MODIFIED CYCLOPENTANE RING. IV. ADENOSINE AND URIDINE ANALOGUES

M. Isabel Nieto Departamento de Química Orgánica, Facultad de Farmacia, Universidad de Santiago, E-15782, Santiago de Compostela, Spain
,
Olga Caamaño Departamento de Química Orgánica, Facultad de Farmacia, Universidad de Santiago, E-15782, Santiago de Compostela, Spain
,
Franco Fernández Departamento de Química Orgánica, Facultad de Farmacia, Universidad de Santiago, E-15782, Santiago de Compostela, Spain
,
María Gómez Departamento de Química Orgánica, Facultad de Farmacia, Universidad de Santiago, E-15782, Santiago de Compostela, Spain
,
Jan Balzarini Rega Institute for Medical Research, Katholieke Universiteit Leuven, Leuven, B-3000, Belgium
&
Erik De Clercq Rega Institute for Medical Research, Katholieke Universiteit Leuven, Leuven, B-3000, Belgium
Pages 243-255 | Received 15 Jun 2001, Accepted 27 Dec 2001, Published online: 17 Aug 2006

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Gülhan Turan-Zitouni, Ahmet Özdemir & Zafer Asım Kaplancıklı. (2011) Synthesis and Antiviral Activity of Some (3,4-Diaryl-3H-thiazol-2-ylidene)pyrimidin-2-yl Amine Derivatives. Phosphorus, Sulfur, and Silicon and the Related Elements 186:2, pages 233-239.
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Liudmila A. Alexandrova, Anastasia L. Khandazhinskaya, Elena S. Matyugina, Dmitriy A. Makarov & Sergey N. Kochetkov. (2022) Analogues of Pyrimidine Nucleosides as Mycobacteria Growth Inhibitors. Microorganisms 10:7, pages 1299.
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Tănase, Drăghici, Hanganu, Pintilie, Maganu, Volobueva, Sinegubova, Zarubaev, Neyts, Jochmans & Slita. (2019) New HSV-1 Anti-Viral 1′-Homocarbocyclic Nucleoside Analogs with an Optically Active Substituted Bicyclo[2.2.1]Heptane Fragment as a Glycoside Moiety. Molecules 24:13, pages 2446.
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Anastasia Khandazhinskaya, Liudmila Alexandrova, Elena Matyugina, Pavel Solyev, Olga Efremenkova, Karen Buckheit, Maggie Wilkinson, Robert BuckheitJr.Jr., Larisa Chernousova, Tatiana Smirnova, Sofya Andreevskaya, Olga Leonova, Vladimir Popenko, Sergey Kochetkov & Katherine Seley-Radtke. (2018) Novel 5′-Norcarbocyclic Pyrimidine Derivatives as Antibacterial Agents. Molecules 23:12, pages 3069.
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Andrzej E. Wróblewski, Iwona E. Głowacka & Dorota G. Piotrowska. (2016) 1′-Homonucleosides and their structural analogues: A review. European Journal of Medicinal Chemistry 118, pages 121-142.
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Evgeny B. Gorbunov, Gennady L. Rusinov, Evgeny N. Ulomsky, Vladimir L. Rusinov, Valery N. Charushin & Oleg N. Chupakhin. (2016) C–H functionalization of triazolo[a]-annulated 8-azapurines. Tetrahedron Letters 57:21, pages 2303-2305.
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Joana Ferreira da Costa, Xerardo García-Mera, Olga Caamaño, José Manuel Brea & María Isabel Loza. (2015) Synthesis by microwave-assisted 1,3-dipolar cycloaddition of 1,2,3-triazole 1′-homo-3′-isoazanucleosides and evaluation of their anticancer activity. European Journal of Medicinal Chemistry 98, pages 212-220.
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Evgeny B. Gorbunov, Gennady L. Rusinov, Evgeny N. Ulomskii, Maksim L. Isenov & Valery N. Charushin. (2015) Synthesis of 2Н-azolo[1,5-а][1,2,3]triazolo[4,5-е]pyrimidines. Chemistry of Heterocyclic Compounds 51:5, pages 491-495.
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Joana Ferreira da Costa, Marcos D. García, Xerardo García-Mera, Isabel Pérez-Castro & Olga Caamaño. (2015) A click chemistry approach to the synthesis of 3′-deoxy-2′-substituted carbanucleoside precursors. Tetrahedron 71:2, pages 324-331.
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Constantin I. Tănase, Constantin Drăghici, Miron Teodor Căproiu, Sergiu Shova, Christophe Mathe, Florea G. Cocu, Cristian Enache & Maria Maganu. (2014) New carbocyclic nucleoside analogues with a bicyclo[2.2.1]heptane fragment as sugar moiety; Synthesis, X-ray crystallography and anticancer activity. Bioorganic & Medicinal Chemistry 22:1, pages 513-522.
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Radek Pohl, Lubomír Rulíšek & Dominik Rejman. (2011) The stability and reactivity of activated acryloylcarbamates as reagents for the synthesis of N-1 substituted thymine and uracil - an NMR and DFT study. Journal of Physical Organic Chemistry 24:5, pages 423-430.
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Shaofa Sun, Li Chen & Xuhong Yang. (2011) A Solution‐Phase Parallel Synthesis of 5‐Substituted 3,6‐Dihydro‐7 H ‐1,2,3‐triazolo[4,5‐ d ]pyrimidin‐7‐ones . Chinese Journal of Chemistry 29:5, pages 991-994.
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Aliuska M. Helguera , J. E. Rodríguez‐Borges, Olga Caamaño, Xerardo García‐Mera, Maykel Pérez González & M. Natália D. S. Cordeiro. (2010) Design, Synthesis, and Evaluation of Antineoplastic Activity of Novel Carbocyclic Nucleosides. Molecular Informatics 29:3, pages 213-231.
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Dominik Rejman, Soňa Kovačková, Radek Pohl, Martin Dračínský, Pavel Fiedler & Ivan Rosenberg. (2009) A convenient, high-yield synthesis of 1-substituted uracil and thymine derivatives. Tetrahedron 65:41, pages 8513-8523.
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Mahesh K. Lakshman, Asad Choudhury, Suyeal Bae, Eliezer Rochttis, Padmanava Pradhan & Amit Kumar. (2008) Synthesis of N6,N6-Dialkyladenine Nucleosides Using Hexaalkylphosphorus Triamides Produced in Situ. European Journal of Organic Chemistry 2009:1, pages 152-159.
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Xiao‐Bao Chen & De‐Qing Shi. (2009) Synthesis and biological activity of 3‐[(6‐chloropyridin‐3‐yl)methyl]‐6‐substituted‐6,7‐dihydro‐3 H ‐1,2,3‐triazolo[4,5‐ d ]‐pyrimidin‐7‐imines . Journal of Heterocyclic Chemistry 45:5, pages 1493-1497.
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Aliuska Morales Helguera, J. E. Rodríguez-Borges, Xerardo García-Mera, Franco Fernández & M. Natália D. S. Cordeiro. (2007) Probing the Anticancer Activity of Nucleoside Analogues:  A QSAR Model Approach Using an Internally Consistent Training Set. Journal of Medicinal Chemistry 50:7, pages 1537-1545.
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Paula Abeijón, José M. Blanco, Franco Fernández, Marcos D. García & Carmen López. (2006) Synthesis of Two Precursors of Heterocarbocyclic Nucleoside Analogues. European Journal of Organic Chemistry 2006:3, pages 759-764.
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Jun-Feng Zhao, Chang Xie, Sheng-Zhen Xu, Ming-Wu Ding & Wen-Jing Xiao. (2006) Iminophosphorane-mediated efficient synthesis of new tricyclic 3,5-dihydro-1,2,3-triazolo[4,5-d]-1,2,4-triazolo[1,5-a]pyrimidin-9-ones. Org. Biomol. Chem. 4:1, pages 130-134.
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Jun-Feng Zhao, Chang Xie, Ming-Wu Ding & Hong-Wu He. (2005) A Selective Synthesis of 3,6-Dihydro-7 H -1,2,3-triazolo[4,5- d ]pyrimidin-7-ones . Chemistry Letters 34:7, pages 1022-1023.
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Tibor Cserháti & Esther Forgács. (2003) Effect of pH and sodium chloride on the strength and selectivity of the interaction of τ-cyclodextrin with some antisense nucleosides. International Journal of Pharmaceutics 254:2, pages 189-196.
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M. Isabel Nieto, Olga Caamano, Franco Fernandez, Maria Gomez, Jan Balzarini & Erik De Clercq. (2010) ChemInform Abstract: Synthesis, Antiviral and Cytostatic Activities, of Carbocyclic Nucleosides Incorporating a Modified Cyclopentane Ring. Part 4. Adenosine and Uridine Analogues.. ChemInform 33:35.
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