Advanced search
Publication Cover
Pharmaceutical Development and Technology Volume 6, 2001 - Issue 4
Submit an article Journal homepage
110
Views
24
CrossRef citations to date
0
Altmetric
Research Article

Interaction of [d-Trp6, Des-Gly10] LHRH Ethylamide and Hydroxy Propyl β-Cyclodextrin (HPβCD): Thermodynamics of Interaction and Protection from Degradation by α-Chymotrypsin

Kavitha N. Koushik Department of Pharmaceutical Sciences, 986025 University of Nebraska Medical Center, Omaha, NE, 68198-6025, U.S.A.
,
Nagesh Bandi Department of Pharmaceutical Sciences, 986025 University of Nebraska Medical Center, Omaha, NE, 68198-6025, U.S.A.
&
Uday B. Kompella Department of Pharmaceutical Sciences, 986025 University of Nebraska Medical Center, Omaha, NE, 68198-6025, U.S.A.
Pages 595-606 | Received 20 Jan 2001, Accepted 31 Mar 2001, Published online: 04 Apr 2002

Citations (24)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (3)

Homa Faghihi, Fatemeh Khalili, Mohsen Amini & Alireza Vatanara. (2017) The effect of freeze-dried antibody concentrations on its stability in the presence of trehalose and hydroxypropyl-β-cyclodextrin: a Box–Behnken statistical design. Pharmaceutical Development and Technology 22:6, pages 724-732.
Read now
Robert D. Healey, Shiva Prasad, Vijaya Rajendram & Pall Thordarson. (2015) Unravelling the interaction between α-cyclodextrin with the thaumatin protein and a peptide mimic. Supramolecular Chemistry 27:5-6, pages 414-419.
Read now
E. Gere‐Pászti, T. Cserháti, E. Forgács, Z. Deyl, I. Miksik, A. Eckhardt & Z. Illés. (2005) Interaction of Hydroxypropyl‐β‐Cyclodextrin with Peptides, Studied by Reversed‐Phase Thin‐Layer Chromatography. Journal of Liquid Chromatography & Related Technologies 28:16, pages 2619-2632.
Read now

Articles from other publishers (21)

Jinghan Li, Hongyue Wang, Lushan Wang, Dongyue Yu & Xiangrong Zhang. (2024) Stabilization effects of saccharides in protein formulations: A review of sucrose, trehalose, cyclodextrins and dextrans. European Journal of Pharmaceutical Sciences 192, pages 106625.
Crossref
Andrea Arsiccio, Tim Sarter, Ilaria Polidori, Gerhard Winter, Roberto Pisano & Joan-Emma Shea. (2023) Thermodynamic Modeling and Experimental Data Reveal That Sugars Stabilize Proteins According to an Excluded Volume Mechanism. Journal of the American Chemical Society 145:30, pages 16678-16690.
Crossref
Tamas Kovacs, Peter Nagy, Gyorgy Panyi, Lajos Szente, Zoltan Varga & Florina Zakany. (2022) Cyclodextrins: Only Pharmaceutical Excipients or Full-Fledged Drug Candidates?. Pharmaceutics 14:12, pages 2559.
Crossref
Nauman Nazeer, Jeffrey R. Simmons, Jan K. Rainey, Juan Carlos Rodriguez-Lecompte & Marya Ahmed. (2021) Antibacterial activities of physiologically stable, self-assembled peptide nanoparticles. Journal of Materials Chemistry B 9:43, pages 9041-9054.
Crossref
Andrea Arsiccio, Marcello Rospiccio, Joan-Emma Shea & Roberto Pisano. (2021) Force Field Parameterization for the Description of the Interactions between Hydroxypropyl-β-Cyclodextrin and Proteins. The Journal of Physical Chemistry B 125:27, pages 7397-7405.
Crossref
Marcello Rospiccio, Andrea Arsiccio, Gerhard Winter & Roberto Pisano. (2021) The Role of Cyclodextrins against Interface-Induced Denaturation in Pharmaceutical Formulations: A Molecular Dynamics Approach. Molecular Pharmaceutics 18:6, pages 2322-2333.
Crossref
Helen Haixia Wu, Patrick Garidel & Blech Michaela. (2021) HP-β-CD for the formulation of IgG and Ig-based biotherapeutics. International Journal of Pharmaceutics 601, pages 120531.
Crossref
Lei Ye, Na-Li Huang, Yi-Xin Du, Marion Schneider & Wei-Dong Du. (2017) Succinyl-β-cyclodextrin modified gold biochip improved seroimmunological detection sensitivity for Lyme disease. Analytica Chimica Acta 953, pages 48-56.
Crossref
Marcella Niccoli, Rosario Oliva & Giuseppina Castronuovo. (2016) Cyclodextrin–protein interaction as inhibiting factor against aggregation. Journal of Thermal Analysis and Calorimetry 127:2, pages 1491-1499.
Crossref
Yulin Qi & Dietrich A. Volmer. (2015) Letter: β-Cyclodextrin Affects the Formation of Isomerization Products during Peptide Deamidation. European Journal of Mass Spectrometry 21:4, pages 701-705.
Crossref
Yulin Qi, Timon Geib & Dietrich A. Volmer. (2015) Determining the Binding Sites of β-Cyclodextrin and Peptides by Electron-Capture Dissociation High Resolution Tandem Mass Spectrometry. Journal of the American Society for Mass Spectrometry 26:7, pages 1143-1149.
Crossref
Prasopchai Tonglairoum, Tanasait Ngawhirunpat, Theerasak Rojanarata, Ruchadaporn Kaomongkolgit & Praneet Opanasopit. (2014) Fast-Acting Clotrimazole Composited PVP/HPβCD Nanofibers for Oral Candidiasis Application. Pharmaceutical Research 31:8, pages 1893-1906.
Crossref
Violeta Yeguas, Muhannad Altarsha, Gérald Monard, Ramón López & Manuel F. Ruiz-López. (2011) Peptide Binding to β-Cyclodextrins: Structure, Dynamics, Energetics, and Electronic Effects. The Journal of Physical Chemistry A 115:42, pages 11810-11817.
Crossref
Tim Serno, Raimund Geidobler & Gerhard Winter. (2011) Protein stabilization by cyclodextrins in the liquid and dried state. Advanced Drug Delivery Reviews 63:13, pages 1086-1106.
Crossref
Victor Sahini & Gabriela Ionita. (2011) Evidence of changes in hydrophilic/hydrophobic balance and in chemical activity of HSA induced by thermal treatments. Open Chemistry 9:2, pages 245-252.
Crossref
Tim Serno, John F. Carpenter, Theodore W. Randolph & Gerhard Winter. (2010) Inhibition of Agitation‐Induced Aggregation of an IgG‐Antibody by Hydroxypropyl‐β‐Cyclodextrin. Journal of Pharmaceutical Sciences 99:3, pages 1193-1206.
Crossref
Giani Andrea Linde, Antonio Laverde Junior, Eliete Vaz de Faria, Nelson Barros Colauto, Flávio Faria de Moraes & Gisella Maria Zanin. (2010) The use of 2D NMR to study β-cyclodextrin complexation and debittering of amino acids and peptides. Food Research International 43:1, pages 187-192.
Crossref
Reynaldo Villalonga, Roberto Cao & Alex Fragoso. (2007) Supramolecular Chemistry of Cyclodextrins in Enzyme Technology. Chemical Reviews 107:7, pages 3088-3116.
Crossref
Nagesh Bandi, William Wei, Christopher B. Roberts, Lakshmi P. Kotra & Uday B. Kompella. (2004) Preparation of budesonide– and indomethacin–hydroxypropyl-β-cyclodextrin (HPBCD) complexes using a single-step, organic-solvent-free supercritical fluid process. European Journal of Pharmaceutical Sciences 23:2, pages 159-168.
Crossref
Julieta B Monteiro, Louise D Chiaradia, Tiago A.S Brandão, Jacir Dal Magro & Rosendo A Yunes. (2003) Enzymatic hydrolysis of diloxanide furoate in the presence of β-cyclodextrin and its methylated derivatives. International Journal of Pharmaceutics 267:1-2, pages 93-100.
Crossref
Matthew J. Cliff & John E. Ladbury. (2003) A survey of the year 2002 literature on applications of isothermal titration calorimetry. Journal of Molecular Recognition 16:6, pages 383-391.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.