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Pharmaceutical Development and Technology Volume 8, 2003 - Issue 4
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Research Article

Effect of Curing Conditions and Plasticizer Level on the Release of Highly Lipophilic Drug from Coated Multiparticulate Drug Delivery System

Ehab Hamed Industrial Pharmacy Program, College of Pharmacy, University of Cincinnati, 3223 Eden Ave, Cincinnati, OH, 45267, USA; CIMA LABS INC., 7325 Aspen Lane, Brooklyn Park, MN, 55428, USA
&
Adel Sakr Industrial Pharmacy Program, College of Pharmacy, University of Cincinnati, 3223 Eden Ave, Cincinnati, OH, 45267, USA
Pages 397-407 | Received 11 Oct 2002, Published online: 18 Sep 2003

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Haitham Ahmad, Ismail Khalifeh, Bashar Alkhalidi, Khaled Aiedeh & Hatim S. AlKhatib. (2014) Application of active layering and coating techniques in the development of a multiparticulate, controlled release dosage form of a high-dose, highly soluble drug. Pharmaceutical Development and Technology 19:5, pages 556-564.
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Articles from other publishers (14)

Abid Riaz Ahmed, Joana Portugal Mota, Ahmad Abdul-Wahhab Shahba & Muhammad Irfan. 2020. Drug Delivery Aspects. Drug Delivery Aspects 33 56 .
Gaith Zoubari, Rebaz Ali & Andriy Dashevskiy. (2019) Water-insoluble polymers as binders for pellet drug layering: Effect on drug release and performance upon compression. International Journal of Pharmaceutics 569, pages 118520.
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Klemen Korasa & Franc Vrečer. (2018) Overview of PAT process analysers applicable in monitoring of film coating unit operations for manufacturing of solid oral dosage forms. European Journal of Pharmaceutical Sciences 111, pages 278-292.
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Klemen Korasa, Grega Hudovornik & Franc Vrečer. (2016) Applicability of near-infrared spectroscopy in the monitoring of film coating and curing process of the prolonged release coated pellets. European Journal of Pharmaceutical Sciences 93, pages 484-492.
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Hussein O. Ammar, Mamdouh M. Ghorab, Linda A. Felton, Shadeed Gad & Aya A. Fouly. (2015) Effect of Antiadherents on the Physical and Drug Release Properties of Acrylic Polymeric Films. AAPS PharmSciTech 17:3, pages 682-692.
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Linda A. Felton. 2015. Encyclopedia of Biomedical Polymers and Polymeric Biomaterials. Encyclopedia of Biomedical Polymers and Polymeric Biomaterials 5797 5814 .
G. Hudovornik & F. Vrečer. (2015) Impact of the curing parameters on drug release from Eudragit RS and RL 30D coated pellets: Design of experiments. Journal of Drug Delivery Science and Technology 30, pages 146-153.
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Al Sayyed Sallam, Sami Nazzal, Hatim S. AlKhatib & Nabil Darwazeh. 2015. Pulmonary Drug Delivery. Pulmonary Drug Delivery 321 338 .
Katja Kristan & Matej Horvat. (2012) Rapid Exploration of Curing Process Design space for Production of Controlled‐Release Pellets. Journal of Pharmaceutical Sciences 101:10, pages 3924-3935.
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Linda A. Felton. 2010. Oral Controlled Release Formulation Design and Drug Delivery. Oral Controlled Release Formulation Design and Drug Delivery 101 114 .
Simon Ensslin, Klaus Peter Moll, Thomas Haefele-Racin & Karsten Mäder. (2009) Safety and Robustness of Coated Pellets: Self-Healing Film Properties and Storage Stability. Pharmaceutical Research 26:6, pages 1534-1543.
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Yasser El-Malah & Sami Nazzal. (2008) Effect of Eudragit® RS 30D and Talc Powder on Verapamil Hydrochloride Release from Beads Coated with Drug Layered Matrices. AAPS PharmSciTech 9:1, pages 75-83.
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Zhi-wei Ye, Patrick Rombout, Jean Paul Remon, Chris Vervaet & Guy Van den Mooter. (2007) Correlation between the permeability of metoprolol tartrate through plasticized isolated ethylcellulose/hydroxypropyl methylcellulose films and drug release from reservoir pellets. European Journal of Pharmaceutics and Biopharmaceutics 67:2, pages 485-490.
Crossref
Ehab Hamed, Myron C Gerson, Ronald W Millard & Adel Sakr. (2003) A study of the pharmacodynamic differences between immediate and extended release bumetanide formulations. International Journal of Pharmaceutics 267:1-2, pages 129-140.
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