Pharmaceutical Development and Technology, Volume 8, Issue 4 (2003)

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Pharmaceutical Development and Technology, Volume 8, Issue 4 (2003)

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Research Article

Article
Studies in Preparation and Evaluation of pH‐Independent Sustained‐Release Matrix Tablets of Verapamil HCl Using Directly Compressible Eudragits
Mukesh C. Gohel, Tejas P. Patel & Shital H. Bariya
Pages: 323-333
Published online: 18 Sep 2003
AbstractforStudies in Preparation and Evaluation of pH‐Independent Sustained‐Release Matrix Tablets of Verapamil HCl Using Directly Compressible Eudragits | Full Text | References | PDF (617.2 KB)
  • 186 Views
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Article
Characterization of Binary Mixtures Consisting of Cross‐Linked High Amylose Starch and Hydroxypropylmethylcellulose Used in the Preparation of Controlled Release Tablets
Miloud Rahmouni, Vincent Lenaerts, Danielle Massuelle, Eric Doelker, Marc Johnson & Jean‐Christophe Leroux
Pages: 335-348
Published online: 18 Sep 2003
AbstractforCharacterization of Binary Mixtures Consisting of Cross‐Linked High Amylose Starch and Hydroxypropylmethylcellulose Used in the Preparation of Controlled Release Tablets | Full Text | References | PDF (723.6 KB)
  • 87 Views
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Article
Using Rate of Acid Neutralization to Characterize Aluminum Phosphate Adjuvant
Dongping Jiang, Clifford T. Johnston & Stanley L. Hem
Pages: 349-356
Published online: 18 Sep 2003
AbstractforUsing Rate of Acid Neutralization to Characterize Aluminum Phosphate Adjuvant | Full Text | References | PDF (453 KB)
  • 120 Views
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Article
Prediction of Tablet Hardness and Porosity Using Near‐Infrared Diffuse Reflectance Spectroscopy as a Nondestructive Method
M. Donoso, D. O. Kildsig & Evone S. Ghaly
Pages: 357-366
Published online: 18 Sep 2003
AbstractforPrediction of Tablet Hardness and Porosity Using Near‐Infrared Diffuse Reflectance Spectroscopy as a Nondestructive Method | Full Text | References | PDF (1.3 MB)
  • 429 Views
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Article
A Novel Approach to Derive a Compression Parameter Indicating Effective Particle Deformability
Göran Alderborn
Pages: 367-377
Published online: 18 Sep 2003
AbstractforA Novel Approach to Derive a Compression Parameter Indicating Effective Particle Deformability | Full Text | References | PDF (666.6 KB)
  • 170 Views
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Article
Effect of Fill Weight, Capsule Shell, and Sinker Design on the Dissolution Behavior of Capsule Formulations of a Weak Acid Drug Candidate BMS‐309403
Yongmei Wu, Fang Zhao & Mehdi Paborji
Pages: 379-383
Published online: 18 Sep 2003
AbstractforEffect of Fill Weight, Capsule Shell, and Sinker Design on the Dissolution Behavior of Capsule Formulations of a Weak Acid Drug Candidate BMS‐309403 | Full Text | References | PDF (375.2 KB)
  • 470 Views
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Article
Solubility of Guaifenesin in the Presence of Common Pharmaceutical Additives
Narasimhan Mani, H. W. Jun, J. Warren Beach & Jayanti Nerurkar
Pages: 385-396
Published online: 18 Sep 2003
AbstractforSolubility of Guaifenesin in the Presence of Common Pharmaceutical Additives | Full Text | References | PDF (618.2 KB)
  • 600 Views
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Article
Effect of Curing Conditions and Plasticizer Level on the Release of Highly Lipophilic Drug from Coated Multiparticulate Drug Delivery System
Ehab Hamed & Adel Sakr
Pages: 397-407
Published online: 18 Sep 2003
AbstractforEffect of Curing Conditions and Plasticizer Level on the Release of Highly Lipophilic Drug from Coated Multiparticulate Drug Delivery System | Full Text | References | PDF (703.3 KB)
  • 195 Views
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Article
A Multi‐mechanistic Drug Release Approach in a Bead Dosage Form and In Vitro/In Vivo Correlations
Ying Liu, Joseph B. Schwartz Ph.D., Roger L. Schnaare & Edwin T. Sugita
Pages: 409-417
Published online: 18 Sep 2003
AbstractforA Multi‐mechanistic Drug Release Approach in a Bead Dosage Form and In Vitro/In Vivo Correlations | Full Text | References | PDF (594.3 KB)
  • 101 Views
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Article
A Multi‐mechanistic Drug Release Approach in a Bead Dosage Form and In Vivo Predictions
Ying Liu, Joseph B. Schwartz Ph.D., Roger L. Schnaare & Edwin T. Sugita
Pages: 419-430
Published online: 18 Sep 2003
AbstractforA Multi‐mechanistic Drug Release Approach in a Bead Dosage Form and In Vivo Predictions | Full Text | References | PDF (868.7 KB)
  • 46 Views
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Article
Use of a Fluidized Bed Hammer Mill for Size Reduction and Classification: Effects of Process Variables and Starting Materials on the Particle Size Distribution of Milled Lactose Batches
C. C. Lee, L. W. Chan & Paul W. S. Heng
Pages: 431-442
Published online: 18 Sep 2003
AbstractforUse of a Fluidized Bed Hammer Mill for Size Reduction and Classification: Effects of Process Variables and Starting Materials on the Particle Size Distribution of Milled Lactose Batches | Full Text | References | PDF (620.1 KB)
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Article
Influence of the Aqueous Film Coating Process on the Properties and Stability of Tablets Containing a Moisture‐Labile Drug
Mirja Ruotsalainen, Jyrki Heinämäki, Krista Taipale & Jouko Yliruusi
Pages: 443-451
Published online: 18 Sep 2003
AbstractforInfluence of the Aqueous Film Coating Process on the Properties and Stability of Tablets Containing a Moisture‐Labile Drug | Full Text | References | PDF (1.1 MB)
  • 358 Views
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Technical Note

Design of Experiment (DOE) Methods Maximize Information from a Minimal Number of Animals in Special Cases of Preclinical Bioavailability Testing
Martin Kuentz, Dieter Röthlisberger & Wolfgang Richter
Pages: 453-458
Published online: 18 Sep 2003
First Page PreviewforDesign of Experiment (DOE) Methods Maximize Information from a Minimal Number of Animals in Special Cases of Preclinical Bioavailability Testing | Full Text | References | PDF (250.6 KB)
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Author Index to Volume 8

Author Index to Volume 8
Pages: 459-461
Published online: 18 Sep 2003
CitationforAuthor Index to Volume 8 | Full Text
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Subject Index to Volume 8

Subject Index to Volume 8
Pages: 463-466
Published online: 18 Sep 2003
CitationforSubject Index to Volume 8 | Full Text
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