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Pharmaceutical Development and Technology Volume 9, 2004 - Issue 1
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Research Article

“Soft Tableting”: A New Concept to Tablet Pressure Sensitive Materials

Katharina M. Picker Institute of Pharmaceutical Technology and Biopharmacy, Martin‐Luther‐University Halle‐Wittenberg, Wolfgang‐Langenbeck‐Str. 4, Halle/Saale, 06120, Germany
Pages 107-121 | Received 21 Jan 2003, Accepted 12 Jul 2003, Published online: 02 Apr 2004

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Tu Van Duong & Guy Van den Mooter. (2016) The role of the carrier in the formulation of pharmaceutical solid dispersions. Part II: amorphous carriers. Expert Opinion on Drug Delivery 13:12, pages 1681-1694.
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Christine Cahyadi, Lai Wah Chan & Paul Wan Sia Heng. (2013) The reality of in-line tablet coating. Pharmaceutical Development and Technology 18:1, pages 2-16.
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Rok Dreu, Ilija Ilić & Stanko Srčič. (2011) Development of a multiple-unit tablet containing enteric-coated pellets. Pharmaceutical Development and Technology 16:2, pages 118-126.
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Wiesław Sawicki, Jarosław Mazgalski & Ilona Jakubowska. (2010) Hot tabletting of slow-release tramadol hydrochloride microcapsules with cores obtained via compaction. Drug Development and Industrial Pharmacy 36:2, pages 209-217.
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Wieslaw Sawicki & Jaroslaw Mazgalski. (2009) Hot tableting as a new method for obtaining tablets from slow release-coated pellets. Drug Development and Industrial Pharmacy 35:7, pages 857-865.
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Oluwatoyin A. Odeku & Katharina M. Picker-Freyer. (2009) Characterization of acid modified Dioscorea starches as direct compression excipient. Pharmaceutical Development and Technology 14:3, pages 259-270.
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Stephanie Hein, Katharina M. Picker-Freyer & John Langridge. (2008) Simulation of Roller Compaction with Subsequent Tableting and Characterization of Lactose and Microcrystalline Cellulose. Pharmaceutical Development and Technology 13:6, pages 523-532.
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Articles from other publishers (23)

Klemen Naveršnik. (2022) A Simple Non-Linear Kinetic Model to Evaluate Stability of a Pressure Sensitive Drug. Journal of Pharmaceutical Sciences 111:11, pages 3108-3113.
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Heejun Park, Jeong-Soo Kim, Seongwoo Hong, Eun-Sol Ha, Haichen Nie, Qi Tony Zhou & Min-Soo Kim. (2022) Tableting process-induced solid-state polymorphic transition. Journal of Pharmaceutical Investigation 52:2, pages 175-194.
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Susanne Page & Anikó Szepes. 2021. Solid State Development and Processing of Pharmaceutical Molecules. Solid State Development and Processing of Pharmaceutical Molecules 325 364 .
Mallesh Kurakula, N. Raghavendra Naveen & Khushwant S. Yadav. 2020. Polymer Coatings. Polymer Coatings 415 443 .
Zhengsong Wang, Zhen Pan, Dakuo He, Jiahui Shi, Shouxin Sun & Yue Hou. (2019) Simulation Modeling of a Pharmaceutical Tablet Manufacturing Process via Wet Granulation. Complexity 2019, pages 1-16.
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Tongkai Chen, Jian Li, Ting Chen, Changquan Calvin Sun & Ying Zheng. (2017) Tablets of multi-unit pellet system for controlled drug delivery. Journal of Controlled Release 262, pages 222-231.
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Dnyaneshwar P. Kale, Sandeep S. Zode & Arvind K. Bansal. (2017) Challenges in Translational Development of Pharmaceutical Cocrystals. Journal of Pharmaceutical Sciences 106:2, pages 457-470.
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Željka Vanić, Odon Planinšek, Nataša Škalko-Basnet & Ingunn Tho. (2014) Tablets of pre-liposomes govern in situ formation of liposomes: Concept and potential of the novel drug delivery system. European Journal of Pharmaceutics and Biopharmaceutics 88:2, pages 443-454.
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John F. Gamble, Magnus Hoffmann, Helen Hughes, Paul Hutchins & Mike Tobyn. (2014) Monitoring process induced attrition of drug substance particles within formulated blends. International Journal of Pharmaceutics 470:1-2, pages 77-87.
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Xiao Lin, Chin Wun Chyi, Ke-feng Ruan, Yi Feng & Paul Wan Sia Heng. (2011) Development of potential novel cushioning agents for the compaction of coated multi-particulates by co-processing micronized lactose with polymers. European Journal of Pharmaceutics and Biopharmaceutics 79:2, pages 406-415.
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Katharina M Picker‐Freyer. 2010. Pharmaceutical Sciences Encyclopedia. Pharmaceutical Sciences Encyclopedia 1 46 .
V. Balzano, G. Betz & H. Leuenberger. (2010) Multiple unit pellet systems (MUPS) obtained by soft compaction of two polymorphic cellulose modifications as coated pellets: influence of the polymorphic modification in MUPS on disintegration time and drug release. International Journal of Biotechnology 11:3/4, pages 182.
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Wolfgang Schmid & Katharina M. Picker-Freyer. (2009) Tableting and tablet properties of alginates: Characterisation and potential for Soft Tableting. European Journal of Pharmaceutics and Biopharmaceutics 72:1, pages 165-172.
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Ravindra Dhumal, Shamkant Shimpi & Anant Paradkar. (2007) Development of spray-dried co-precipitate of amorphous celecoxib containing storage and compression stabilizers. Acta Pharmaceutica 57:3, pages 287-300.
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Oluwatoyin A. Odeku & Katharina M. Picker‐Freyer. (2007) Analysis of the Material and Tablet Formation Properties of four Dioscorea Starches . Starch - Stärke 59:9, pages 430-444.
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Katharina Maria Picker-Freyer. (2007) The 3-D model: Experimental Testing of the Parameters d, e, and ω and Validation of the Analysis. Journal of Pharmaceutical Sciences 96:5, pages 1408-1417.
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A. Szepes, A. Fehér, P. Szabó‐Révész & J. Ulrich. (2007) Influence of Freezing Temperature on Product Parameters of Solid Dosage Forms Prepared via the Freeze‐Casting Technique. Chemical Engineering & Technology 30:4, pages 511-516.
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Anikó Szepes, Joachim Ulrich, Zsuzsanna Farkas, József Kovács & Piroska Szabó-Révész. (2007) Freeze-casting technique in the development of solid drug delivery systems. Chemical Engineering and Processing: Process Intensification 46:3, pages 230-238.
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Shamkant Shimpi, Kakasaheb Mahadik, Kanji Takada & Anant Paradkar. (2007) Application of Polyglycolized Glycerides in Protection of Amorphous Form of Etoricoxib during Compression. Chemical and Pharmaceutical Bulletin 55:10, pages 1448-1451.
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Katharina M. Picker-Freyer & Diana Brink. (2017) Evaluation of powder and tableting properties of chitosan. AAPS PharmSciTech 7:3, pages E152-E161.
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Karsten Hauschild & Katharina M. Picker. (2015) Evaluation of a new coprocessed compound based on lactose and maize starch for tablet formulation. AAPS PharmSci 6:2, pages 27-38.
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Andrea G. Schmidt, Siegfried Wartewig & Katharina M. Picker. (2004) Polyethylene oxides: protection potential against polymorphic transitions of drugs?. Journal of Raman Spectroscopy 35:5, pages 360-367.
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Katharina M. Picker. (2003) The 3-D model: Does time plasticity represent the influence of tableting speed?. AAPS PharmSciTech 4:4, pages 523-530.
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