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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 35, 2005 - Issue 10
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Original Articles

Simple, Extremely Fast, and High‐Yielding Oxidation of Thiols to Disulfides

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Pages 1329-1333 | Received 08 Dec 2004, Published online: 16 Aug 2006

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Kiumars Bahrami, MohammadM. Khodaei, Vida Shakibaian & Homa Targhan. (2013) Rapid and Convenient Method for the Synthesis of Symmetrical Disulfides. Phosphorus, Sulfur, and Silicon and the Related Elements 188:8, pages 981-988.
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DaianeM.L. Cabrera, FrancieliM. Líbero, Diego Alves, Gelson Perin, EderJ. Lenardão & RaquelG. Jacob. (2012) Glycerol as a recyclable solvent in a microwave-assisted synthesis of disulfides. Green Chemistry Letters and Reviews 5:3, pages 329-336.
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Arash Ghorbani-Choghamarani, Mohammad Soleiman-Beigi & Farid Noormohammadi. (2011) Trimethylphenylammonium Tribromide as a New and Efficient Oxidizing Agent for the Oxidative Coupling of Thiols into Disulfides and Chemoselective Oxidation of Sulfides into Sulfoxides. Phosphorus, Sulfur, and Silicon and the Related Elements 186:8, pages 1665-1672.
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Arash Ghorbani-Choghamarani & Sara Sardari. (2011) Green preparation of disulfides from corresponding thiols by poly(4-vinylpyridinium nitrate) as recoverable and new polymeric reagent. Journal of Sulfur Chemistry 32:1, pages 63-69.
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W. Marjit Singh & JubarajB. Baruah. (2008) Rosolic Acid–Catalyzed Conversion of Thiols to Disulfides. Synthetic Communications 39:2, pages 325-331.
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Articles from other publishers (24)

Lin Yao, Wenjian Li, Fuhong Xiao & Guo-Jun Deng. (2023) Three-Component Tandem Amidosulfenylation of Alkenes for the Synthesis of β-Succinimide Sulfides. The Journal of Organic Chemistry.
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Mohammad Soleiman-Beigi, Mohammad Alikarami, Homa Kohzadi & Zahra Akbari. (2022) Dipotassium 1,3,4-thiadiazole-2,5-bis(thiolate) as a new S-donor for direct synthesis of symmetrical disulfides. Scientific Reports 12:1.
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赛米 乃比江·. (2022) Synthesis Study of Disulfides Promoted by Benzoyl Peroxide. Hans Journal of Chemical Engineering and Technology 12:03, pages 188-193.
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Gincy M Mathew, Aravind Madhavan, K. B. Arun, Raveendran Sindhu, Parameswaran Binod, Reeta Rani Singhania, Rajeev K Sukumaran & Ashok Pandey. (2020) Thermophilic Chitinases: Structural, Functional and Engineering Attributes for Industrial Applications. Applied Biochemistry and Biotechnology 193:1, pages 142-164.
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Caroline S. Sauer, Johannes Köckenberger & Markus R. Heinrich. (2020) Oxidative Formation of Disulfide Bonds by a Chemiluminescent 1,2-Dioxetane under Mild Conditions. The Journal of Organic Chemistry 85:14, pages 9331-9338.
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Mozafar Mohammadi, Amirhossein Sakhteman, Sajjad Ahrari, Kazem Hassanpour, Sayed Ebrahim Hashemi & Gholamreza Farnoosh. (2018) Disulfide bridge formation to increase thermostability of DFPase enzyme: A computational study. Computational Biology and Chemistry 77, pages 272-278.
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Ehsan Rezaie, Mozafar Mohammadi, Amirhossein Sakhteman, Peyman Bemani & Sajjad Ahrari. (2018) Application of molecular dynamics simulations to design a dual-purpose oligopeptide linker sequence for fusion proteins. Journal of Molecular Modeling 24:11.
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Ming Wang & Xuefeng Jiang. (2018) Sulfur–Sulfur Bond Construction. Topics in Current Chemistry 376:2.
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M. Rachèl Elzes, Niels Akeroyd, Johan F.J. Engbersen & Jos M.J. Paulusse. (2016) Disulfide-functional poly(amido amine)s with tunable degradability for gene delivery. Journal of Controlled Release 244, pages 357-365.
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Indranirekha Saikia, Arun Jyoti Borah & Prodeep Phukan. (2016) Use of Bromine and Bromo-Organic Compounds in Organic Synthesis. Chemical Reviews 116:12, pages 6837-7042.
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Zhanguo Chen, Manfei Du, Wei Xia & Junli Hu. (2016) One-pot synthesis of α,β-dehydroamino derivatives from β,β-dicyanostyrene with 1,3-dibromo-5,5-dimethylhydantoin promoted by mild base. Chemical Research in Chinese Universities 32:1, pages 68-75.
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Zhanguo Chen, Wei Xia, De'e Liu, Yali Liu, Manfei Du & Chenxi Cao. (2015) NaHCO 3 ‐Catalyzed Hihgly Regiospecific Aminobromination of ß,ß‐Dicyanostyrene Derivatives with 1,3‐Dibromo‐5,5‐dimethylhydantoin (DBDMH) . Journal of the Chinese Chemical Society 63:2, pages 158-164.
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Suvendu Samanta, Shounak Ray, Abhisek Brata Ghosh & Papu Biswas. (2016) 3,6-Di(pyridin-2-yl)-1,2,4,5-tetrazine (pytz) mediated metal-free mild oxidation of thiols to disulfides in aqueous medium. RSC Adv. 6:45, pages 39356-39363.
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Mohammad Abbasi & Arida Jabbari. (2015) One-pot conversion of alkyl halides to organic disulfides (disulfanes) using thiourea and hexamethyldisilazane (HMDS) in DMSO. Journal of the Iranian Chemical Society 13:1, pages 81-86.
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Zhanguo Chen, Yali Liu, Junli Hu & De’e Liu. (2015) Aminobromination of ethyl α-cyanocinnamate derivatives with 1,3-dibromo-5,5-dimethylhydantoin(DBDMH) as nitrogen and halogen sources. Chemical Research in Chinese Universities 31:1, pages 65-70.
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Jing Chen, Cheng-Shi Jiang, Wen-Quan Ma, Li-Xin Gao, Jing-Xu Gong, Jing-Ya Li, Jia Li & Yue-Wei Guo. (2013) The first synthesis of natural disulfide bruguiesulfurol and biological evaluation of its derivatives as a novel scaffold for PTP1B inhibitors. Bioorganic & Medicinal Chemistry Letters 23:18, pages 5061-5065.
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Ramanjaneyulu Rayala & Stanislaw F. Wnuk. (2012) Bromination at C-5 of pyrimidine and C-8 of purine nucleosides with 1,3-dibromo-5,5-dimethylhydantoin. Tetrahedron Letters 53:26, pages 3333-3336.
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Giuseppe La Regina, Valerio Gatti, Valeria Famiglini, Francesco Piscitelli & Romano Silvestri. (2012) Venting-while-Heating Microwave-Assisted Synthesis of 3-Arylthioindoles. ACS Combinatorial Science 14:4, pages 258-262.
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ARASH GHORBANI-CHOGHAMARANI, MOHSEN NIKOORAZM, HAMID GOUDARZIAFSHAR, ALIREZA SHOKR & HOSEIN ALMASI. (2011) Metal-free oxidative coupling of thiols to disulfides using guanidinium nitrate or nitro urea in the presence of silica sulfuric acid. Journal of Chemical Sciences 123:4, pages 453-457.
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Samuel Thurow, Vanda A. Pereira, Débora M. Martinez, Diego Alves, Gelson Perin, Raquel G. Jacob & Eder J. Lenardão. (2011) Base-free oxidation of thiols to disulfides using selenium ionic liquid. Tetrahedron Letters 52:5, pages 640-643.
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Vinod Kumar & Mahabir Parshad Kaushik. (2008) Efficient Oxidative Coupling of Thiols into Disulfides Using N - tert -Butyl- N -chlorocyanamide . Bulletin of the Chemical Society of Japan 81:1, pages 160-162.
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Eder J. Lenardão, Renata G. Lara, Márcio S. Silva, Raquel G. Jacob & Gelson Perin. (2007) Clean and fast oxidative transformation of thiols to disulfides under solvent-free conditions. Tetrahedron Letters 48:43, pages 7668-7670.
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Jing-Xu Gong, Xu Shen, Li-Gong Yao, Hualiang Jiang, Karsten Krohn & Yue-Wei Guo. (2007) Total Synthesis of Gymnorrhizol, an Unprecedented 15-Membered Macrocyclic Polydisulfide from the Chinese Mangrove Bruguiera gymnorrhiza . Organic Letters 9:9, pages 1715-1716.
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Ashraful Alam, Yutaka Takaguchi & Sadao Tsuboi. (2005) Simple, Extremely Fast, and High‐Yielding Oxidation of Thiols to Disulfides. ChemInform 36:41.
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