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Molecular and Cellular Biology Volume 30, 2010 - Issue 14
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Article

Role of the GATA-1/FOG-1/NuRD Pathway in the Expression of Human β-Like Globin Genes

Annarita Miccio1 Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania19104
&
Gerd A. Blobel1 Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania19104;2 University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania19104Correspondence[email protected]
Pages 3460-3470 | Received 02 Jan 2010, Accepted 26 Apr 2010, Published online: 20 Mar 2023

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Julita Ramírez, Carissa Dege, Tatiana G. Kutateladze & James Hagman. (2012) MBD2 and Multiple Domains of CHD4 Are Required for Transcriptional Repression by Mi-2/NuRD Complexes. Molecular and Cellular Biology 32:24, pages 5078-5088.
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J. Basta & M. Rauchman. 2017. Translating Epigenetics to the Clinic. Translating Epigenetics to the Clinic 37 72 .
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Linda Wolff & Rita Humeniuk. (2013) Concise Review: Erythroid Versus Myeloid Lineage Commitment: Regulating the Master Regulators. Stem Cells 31:7, pages 1237-1244.
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Maria AmayaMegha DesaiMerlin Nithya GnanapragasamShou Zhen WangSheng Zu ZhuDavid C. WilliamsJrJr & Gordon D. Ginder. (2013) Mi2β-mediated silencing of the fetal γ-globin gene in adult erythroid cells. Blood 121:17, pages 3493-3501.
Crossref
Flávia C. Costa, Halyna Fedosyuk, Allen M. Chazelle, Renee Y. Neades & Kenneth R. Peterson. (2012) Mi2β Is Required for γ-Globin Gene Silencing: Temporal Assembly of a GATA-1-FOG-1-Mi2 Repressor Complex in β-YAC Transgenic Mice. PLoS Genetics 8:12, pages e1003155.
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Timothy M. Chlon & John D. Crispino. (2012) Combinatorial regulation of tissue specification by GATA and FOG factors. Development 139:21, pages 3905-3916.
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Holly Hung, Rebecca Kohnken & John Svaren. (2012) The Nucleosome Remodeling and Deacetylase Chromatin Remodeling (NuRD) Complex Is Required for Peripheral Nerve Myelination. The Journal of Neuroscience 32:5, pages 1517-1527.
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Annarita Miccio, Valentina Poletti, Francesca Tiboni, Claudia Rossi, Antonella Antonelli, Fulvio Mavilio & Giuliana Ferrari. (2011) The GATA1-HS2 Enhancer Allows Persistent and Position-Independent Expression of a β-globin Transgene. PLoS ONE 6:12, pages e27955.
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Hsiang-Ying Lee, Kirby D. Johnson, Meghan E. Boyer & Emery H. Bresnick. (2011) Relocalizing Genetic Loci into Specific Subnuclear Neighborhoods. Journal of Biological Chemistry 286:21, pages 18834-18844.
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Daniel E Bauer & Stuart H Orkin. (2011) Update on fetal hemoglobin gene regulation in hemoglobinopathies. Current Opinion in Pediatrics 23:1, pages 1-8.
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