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Article

Functional and Biochemical Characterization of Human Eukaryotic Translation Initiation Factor 3 in Living Cells

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Pages 3041-3052 | Received 14 May 2014, Accepted 04 Jun 2014, Published online: 20 Mar 2023

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Kunrao Li, Shuru Zhou, Qixuan Guo, Xin Chen, De-hua Lai, Zhao-rong Lun & Xuemin Guo. (2017) The eIF3 complex of Trypanosoma brucei : composition conservation does not imply the conservation of structural assembly and subunits function . RNA 23:3, pages 333-345.
Crossref
Prasanna Parasuraman, Peter Mulligan, James A. Walker, Bihua Li, Myriam Boukhali, Wilhelm Haas & Andre Bernards. (2017) Interaction of p190A RhoGAP with eIF3A and Other Translation Preinitiation Factors Suggests a Role in Protein Biosynthesis. Journal of Biological Chemistry 292:7, pages 2679-2689.
Crossref
Rita Seeböck, Nicole Golob-Schwarzl & Stefanie Krassnig. 2017. Mechanisms of Molecular Carcinogenesis – Volume 1. Mechanisms of Molecular Carcinogenesis – Volume 1 77 86 .
Susan Wagner, Anna Herrmannová, Darina Šikrová & Leoš Shivaya Valášek. (2016) Human eIF3b and eIF3a serve as the nucleation core for the assembly of eIF3 into two interconnected modules: the yeast-like core and the octamer. Nucleic Acids Research 44:22, pages 10772-10788.
Crossref
Yaying Lin, Rongrong Zhang & Ping Zhang. (2016) Eukaryotic translation initiation factor 3 subunit D overexpression is associated with the occurrence and development of ovarian cancer. FEBS Open Bio 6:12, pages 1201-1210.
Crossref
Qian Zhu, Guo-Liang Qiao, Xiao-Chuan Zeng, Yun Li, Jian-Jun Yan, Rui Duan & Zhi-Yong Du. (2016) Elevated expression of eukaryotic translation initiation factor 3H is associated with proliferation, invasion and tumorigenicity in human hepatocellular carcinoma. Oncotarget 7:31, pages 49888-49901.
Crossref
Meera Shah, Dan Su, Judith S. Scheliga, Tomáš Pluskal, Susanna Boronat, Khatereh Motamedchaboki, Alexandre Rosa Campos, Feng Qi, Elena Hidalgo, Mitsuhiro Yanagida & Dieter A. Wolf. (2016) A Transcript-Specific eIF3 Complex Mediates Global Translational Control of Energy Metabolism. Cell Reports 16:7, pages 1891-1902.
Crossref
M. Duane Smith, Luisa Arake-Tacca, Adam Nitido, Elizabeth Montabana, Annsea Park & Jamie H. Cate. (2016) Assembly of eIF3 Mediated by Mutually Dependent Subunit Insertion. Structure 24:6, pages 886-896.
Crossref
Amedee des Georges, Vidya Dhote, Lauriane Kuhn, Christopher U. T. Hellen, Tatyana V. Pestova, Joachim Frank & Yaser Hashem. (2015) Structure of mammalian eIF3 in the context of the 43S preinitiation complex. Nature 525:7570, pages 491-495.
Crossref
Francisco J.C. Pereira, Alexandre Teixeira, Jian Kong, Cristina Barbosa, Ana Luísa Silva, Ana Marques-Ramos, Stephen A. Liebhaber & Luísa Romão. (2015) Resistance of mRNAs with AUG-proximal nonsense mutations to nonsense-mediated decay reflects variables of mRNA structure and translational activity. Nucleic Acids Research 43:13, pages 6528-6544.
Crossref
Hongyu Han, Chunlin Kong, Hui Dong, Shunhai Zhu, Qiping Zhao, Qi Zhai, Siting Liang, Sha Li, Shihan Yang & Bing Huang. (2015) Molecular characterization and functional analysis of subunit 7 of eukaryotic initiation factor 3 from Eimeria tenella. Experimental Parasitology 154, pages 118-126.
Crossref
Christian Borgo, Cinzia Franchin, Valentina Salizzato, Luca Cesaro, Giorgio Arrigoni, Laura Matricardi, Lorenzo A. Pinna & Arianna Donella-Deana. (2015) Protein kinase CK2 potentiates translation efficiency by phosphorylating eIF3j at Ser127. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1853:7, pages 1693-1701.
Crossref
John W.B. Hershey. (2015) The role of eIF3 and its individual subunits in cancer. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1849:7, pages 792-800.
Crossref
Petra Beznosková, Susan Wagner, Myrte Esmeralda Jansen, Tobias von der Haar & Leoš Shivaya Valášek. (2015) Translation initiation factor eIF3 promotes programmed stop codon readthrough. Nucleic Acids Research 43:10, pages 5099-5111.
Crossref
Antonio M Rezende, Ludmila A Assis, Eduardo C Nunes, Tamara D da Costa Lima, Fabricio K Marchini, Eden R Freire, Christian RS Reis & Osvaldo P de Melo Neto. (2014) The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates – identification of conserved and divergent features based on orthologue analysis. BMC Genomics 15:1.
Crossref
Karim Majzoub, Mohamed Lamine Hafirassou, Carine Meignin, Akira Goto, Stefano Marzi, Antonina Fedorova, Yann Verdier, Joëlle Vinh, Jules A. Hoffmann, Franck Martin, Thomas F. Baumert, Catherine Schuster & Jean-Luc Imler. (2014) RACK1 Controls IRES-Mediated Translation of Viruses. Cell 159:5, pages 1086-1095.
Crossref

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