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Article

Functional Interplay between Histone Demethylase and Deacetylase Enzymes

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Pages 6395-6402 | Received 26 Apr 2006, Accepted 07 Jun 2006, Published online: 27 Mar 2023

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Archana SehrawatLina GaoYuliang WangArmand BankheadIIIIIIShannon K. McWeeney, Carly J. KingJacob SchwartzmanJoshua UrrutiaWilliam H. BissonDaniel J. ColemanSunil K. JoshiDae-Hwan KimDavid A. SampsonSheila WeinmannBhaskar V. S. KallakuryDeborah L. BerryReina HaqueStephen K. Van Den EedenSunil SharmaJared BearssTomasz M. BeerGeorge V. Thomas, Laura M. HeiserJoshi J. Alumkal. (2018) LSD1 activates a lethal prostate cancer gene network independently of its demethylase function. Proceedings of the National Academy of Sciences 115:18.
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Crossref
Amir Hosseini & Saverio Minucci. 2018. Epigenetics in Human Disease. Epigenetics in Human Disease 141 217 .
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Crossref
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Crossref
Susanna Ambrosio, Carmen D. Saccà & Barbara Majello. (2017) Epigenetic regulation of epithelial to mesenchymal transition by the Lysine-specific demethylase LSD1/KDM1A. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1860:9, pages 905-910.
Crossref
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Crossref
Runsheng He & Benjamin L. Kidder. (2017) H3K4 demethylase KDM5B regulates global dynamics of transcription elongation and alternative splicing in embryonic stem cells. Nucleic Acids Research 45:11, pages 6427-6441.
Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Arianna BottoniLara RizzottoTzung-Huei LaiChaomei Liu, Lisa L. SmithRose MantelSean ReiffDalia El-GamalKarilyn LarkinAmy J. JohnsonRosa LapalombellaAmy Lehman, William Plunkett, John C. ByrdJames S. BlachlyJennifer A. WoyachDeepa Sampath. (2016) Targeting BTK through microRNA in chronic lymphocytic leukemia. Blood 128:26, pages 3101-3112.
Crossref
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Emily L. Ricq, Jacob M. Hooker & Stephen J. Haggarty. (2016) Toward development of epigenetic drugs for central nervous system disorders: Modulating neuroplasticity via H3K4 methylation . Psychiatry and Clinical Neurosciences 70:12, pages 536-550.
Crossref
Urszula PolakYanjie LiJill Sergesketter ButlerMarek Napierala. (2016) Alleviating GAA Repeat Induced Transcriptional Silencing of the Friedreich's Ataxia Gene During Somatic Cell Reprogramming. Stem Cells and Development 25:23, pages 1788-1800.
Crossref
Christopher J. Petell, Lama Alabdi, Ming He, Phillip San Miguel, Richard Rose & Humaira Gowher. (2016) An epigenetic switch regulates de novo DNA methylation at a subset of pluripotency gene enhancers during embryonic stem cell differentiation . Nucleic Acids Research 44:16, pages 7605-7617.
Crossref
Alba Maiques-Diaz & Tim CP Somervaille. (2016) LSD1: biologic roles and therapeutic targeting. Epigenomics 8:8, pages 1103-1116.
Crossref
Simona Pilotto, Valentina Speranzini, Chiara Marabelli, Francesco Rusconi, Emanuela Toffolo, Barbara Grillo, Elena Battaglioli & Andrea Mattevi. (2016) LSD1/KDM1A mutations associated to a newly described form of intellectual disability impair demethylase activity and binding to transcription factors. Human Molecular Genetics, pages ddw120.
Crossref
Francesco RusconiBarbara GrilloLuisa PonzoniSilvia BassaniEmanuela ToffoloLeda PaganiniAlessandra Mallei, Daniela BraidaMaria PassafaroMaurizio Popoli, Mariaelvina SalaElena Battaglioli. (2016) LSD1 modulates stress-evoked transcription of immediate early genes and emotional behavior. Proceedings of the National Academy of Sciences 113:13, pages 3651-3656.
Crossref
Silvia Consalvi, Martina Sandoná & Valentina Saccone. (2016) Epigenetic Reprogramming of Muscle Progenitors: Inspiration for Clinical Therapies. Stem Cells International 2016, pages 1-11.
Crossref
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Crossref
M.J. Lamberti, R.E. Vera, N.B. Rumie Vittar & G. Schneider. 2016. Chromatin Signaling and Diseases. Chromatin Signaling and Diseases 169 178 .
Toshitsugu Fujita & Hodaka Fujii. (2015) Applications of Engineered DNA-Binding Molecules Such as TAL Proteins and the CRISPR/Cas System in Biology Research. International Journal of Molecular Sciences 16:10, pages 23143-23164.
Crossref
Jonathan M. Burg, Alan T. Makhoul, Charles W. Pemble, Jennifer E. Link, Frederick J. Heller & Dewey G. McCafferty. (2015) A rationally-designed chimeric KDM1A/KDM1B histone demethylase tower domain deletion mutant retaining enzymatic activity. FEBS Letters 589:18, pages 2340-2346.
Crossref
Joe A. Arosh, JeHoon Lee, Anna Starzinski-Powitz & Sakhila K. Banu. (2015) Selective inhibition of prostaglandin E2 receptors EP2 and EP4 modulates DNA methylation and histone modification machinery proteins in human endometriotic cells. Molecular and Cellular Endocrinology 409, pages 51-58.
Crossref
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Crossref
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Crossref
Sohini Mazumdar, Lisa M. Arendt, Sarah Phillips, Maja Sedic, Charlotte Kuperwasser & Grace Gill. (2015) CoREST1 Promotes Tumor Formation and Tumor Stroma Interactions in a Mouse Model of Breast Cancer. PLOS ONE 10:3, pages e0121281.
Crossref
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Crossref
Christopher J. Millard & John W. R. Schwabe. 2015. Nuclear Receptors: From Structure to the Clinic. Nuclear Receptors: From Structure to the Clinic 155 175 .
Xuncheng Liu, Ming Luo, Songguang Yang & Keqiang Wu. 2015. Nuclear Functions in Plant Transcription, Signaling and Development. Nuclear Functions in Plant Transcription, Signaling and Development 81 92 .
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Crossref
Setsuya Fujita. (2014) 50 years of research on the phenomena and epigenetic mechanism of neurogenesis. Neuroscience Research 86, pages 3-13.
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Alison M. Urvalek & Lorraine J. Gudas. (2014) Retinoic Acid and Histone Deacetylases Regulate Epigenetic Changes in Embryonic Stem Cells. Journal of Biological Chemistry 289:28, pages 19519-19530.
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Anne Laugesen & Kristian Helin. (2014) Chromatin Repressive Complexes in Stem Cells, Development, and Cancer. Cell Stem Cell 14:6, pages 735-751.
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. (2014) 50 years of research on the phenomena and epigenetic mechanism of neurogenesis. Neuroscience Research 83, pages 43-53.
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Shilpa S. Dhar, Hunain Alam, Na Li, Klaus W. Wagner, Jimyung Chung, Yeo Won Ahn & Min Gyu Lee. (2014) Transcriptional Repression of Histone Deacetylase 3 by the Histone Demethylase KDM2A Is Coupled to Tumorigenicity of Lung Cancer Cells. Journal of Biological Chemistry 289:11, pages 7483-7496.
Crossref
Marzena Maćkowiak, Ewelina Bator, Joachim Latusz, Patrycja Mordalska & Krzysztof Wędzony. (2014) Prenatal MAM administration affects histone H3 methylation in postnatal life in the rat medial prefrontal cortex. European Neuropsychopharmacology 24:2, pages 271-289.
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Dongmei Zhu, Stefanie Hölz, Eric Metzger, Mihael Pavlovic, Anett Jandausch, Cordula Jilg, Petra Galgoczy, Corinna Herz, Markus Moser, Daniel Metzger, Thomas Günther, Sebastian J. Arnold & Roland Schüle. (2014) Lysine-specific demethylase 1 regulates differentiation onset and migration of trophoblast stem cells. Nature Communications 5:1.
Crossref
Benjamin L Kidder, Gangqing Hu & Keji Zhao. (2014) KDM5B focuses H3K4 methylation near promoters and enhancers during embryonic stem cell self-renewal and differentiation. Genome Biology 15:2, pages R32.
Crossref
Fatima El Mansouri, Salwa-Sarah Nebbaki, Mohit Kapoor, Hassan Afif, Johanne Martel-Pelletier, Jean-Pierre Pelletier, Mohamed Benderdour & Hassan Fahmi. (2014) Lysine-specific demethylase 1-mediated demethylation of histone H3 lysine 9 contributes to interleukin 1β-induced microsomal prostaglandin E synthase 1 expression in human osteoarthritic chondrocytes. Arthritis Research & Therapy 16:3, pages R113.
Crossref
Esther Jortzik, Lihui Wang, Jipeng Ma & Katja Becker. 2014. Flavins and Flavoproteins. Flavins and Flavoproteins 113 157 .
Chun Ruan & Bing Li. 2014. Fundamentals of Chromatin. Fundamentals of Chromatin 355 373 .
Anne-Lise Steunou, Dorine Rossetto & Jacques Côté. 2014. Fundamentals of Chromatin. Fundamentals of Chromatin 147 212 .
Kristian W Pajtler, Christina Weingarten, Theresa Thor, Annette Künkele, Lukas C Heukamp, Reinhard Büttner, Takayoshi Suzuki, Naoki Miyata, Michael Grotzer, Anja Rieb, Annika Sprüssel, Angelika Eggert, Alexander Schramm & Johannes H Schulte. (2013) The KDM1A histone demethylase is a promising new target for the epigenetic therapy of medulloblastoma. Acta Neuropathologica Communications 1:1.
Crossref
Jonas W. Højfeldt, Karl Agger & Kristian Helin. (2013) Histone lysine demethylases as targets for anticancer therapy. Nature Reviews Drug Discovery 12:12, pages 917-930.
Crossref
Eric M Mendenhall, Kaylyn E Williamson, Deepak Reyon, James Y Zou, Oren Ram, J Keith Joung & Bradley E Bernstein. (2013) Locus-specific editing of histone modifications at endogenous enhancers. Nature Biotechnology 31:12, pages 1133-1136.
Crossref
Thomas Rudolph, Stefanie Beuch & Gunter Reuter. (2013) Lysine-specific histone demethylase LSD1 and the dynamic control of chromatin. bchm 394:8, pages 1019-1028.
Crossref
Christopher J. Millard, Peter J. Watson, Ivana Celardo, Yuliya Gordiyenko, Shaun M. Cowley, Carol V. Robinson, Louise Fairall & John W.R. Schwabe. (2013) Class I HDACs Share a Common Mechanism of Regulation by Inositol Phosphates. Molecular Cell 51:1, pages 57-67.
Crossref
Richard D.W. KellyShaun M. Cowley. (2013) The physiological roles of histone deacetylase (HDAC) 1 and 2: complex co-stars with multiple leading parts. Biochemical Society Transactions 41:3, pages 741-749.
Crossref
Guillermo Pablo Vicent, A. Silvina Nacht, Roser Zaurin, Jofre Font-Mateu, Daniel Soronellas, Francois Le Dily, Diana Reyes & Miguel Beato. (2013) Unliganded progesterone receptor-mediated targeting of an RNA-containing repressive complex silences a subset of hormone-inducible genes. Genes & Development 27:10, pages 1179-1197.
Crossref
Conchi Estarás, Raquel Fueyo, Naiara Akizu, Sergi Beltrán & Marian A. Martínez-Balbás. (2013) RNA polymerase II progression through H3K27me3-enriched gene bodies requires JMJD3 histone demethylase. Molecular Biology of the Cell 24:3, pages 351-360.
Crossref
Lauren B Auriemma, Shaili Shah, Lara M Linden & Melissa A Henriksen. (2012) Knockdown of menin affects pre-mRNA processing and promoter fidelity at the interferon-gamma inducible IRF1 gene. Epigenetics & Chromatin 5:1.
Crossref
Y Li, C Deng, X Hu, B Patel, X Fu, Y Qiu, M Brand, K Zhao & S Huang. (2012) Dynamic interaction between TAL1 oncoprotein and LSD1 regulates TAL1 function in hematopoiesis and leukemogenesis. Oncogene 31:48, pages 5007-5018.
Crossref
I-Peng Chen, Stefan Henning, Alexandra Faust, Petra Boukamp, Beate Volkmer & Rüdiger Greinert. (2012) UVA-induced epigenetic regulation of P16INK4a in human epidermal keratinocytes and skin tumor derived cells. Photochemical & Photobiological Sciences 11:1, pages 180-190.
Crossref
Hongwei Yao & Irfan Rahman. (2012) Role of histone deacetylase 2 in epigenetics and cellular senescence: implications in lung inflammaging and COPD. American Journal of Physiology-Lung Cellular and Molecular Physiology 303:7, pages L557-L566.
Crossref
Conchi Estarás, Naiara Akizu, Alejandra García, Sergi Beltrán, Xavier de la Cruz & Marian A. Martínez-Balbás. (2012) Genome-wide analysis reveals that Smad3 and JMJD3 HDM co-activate the neural developmental program. Development 139:15, pages 2681-2691.
Crossref
Ming Luo, Yu-Yuan Wang, Xuncheng Liu, Songguang Yang, Qing Lu, Yuhai Cui & Keqiang Wu. (2012) HD2C interacts with HDA6 and is involved in ABA and salt stress response in Arabidopsis. Journal of Experimental Botany 63:8, pages 3297-3306.
Crossref
HYUNSOO SHIN, YEO SONG LEE & YONG CHAN LEE. (2012) Sodium butyrate-induced DAPK-mediated apoptosis in human gastric cancer cells. Oncology Reports 27:4, pages 1111-1115.
Crossref
Warren A. Whyte, Steve Bilodeau, David A. Orlando, Heather A. Hoke, Garrett M. Frampton, Charles T. Foster, Shaun M. Cowley & Richard A. Young. (2012) Enhancer decommissioning by LSD1 during embryonic stem cell differentiation. Nature 482:7384, pages 221-225.
Crossref
Ming Luo, Xuncheng Liu, Prashant Singh, Yuhai Cui, Laurent Zimmerli & Keqiang Wu. (2012) Chromatin modifications and remodeling in plant abiotic stress responses. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1819:2, pages 129-136.
Crossref
Xuncheng Liu, Chun-Wei Yu, Jun Duan, Ming Luo, Koching Wang, Gang Tian, Yuhai Cui & Keqiang Wu. (2012) HDA6 Directly Interacts with DNA Methyltransferase MET1 and Maintains Transposable Element Silencing in Arabidopsis    . Plant Physiology 158:1, pages 119-129.
Crossref
Thomas B Nicholson, Hui Su, Sarah Hevi, Jing Wang, Jeff Bajko, Mei Li, Reginald Valdez, Joseph Loureiro, Xiaodong Cheng, En Li, Bernd Kinzel, Mark Labow & Taiping Chen. (2011) Defective heart development in hypomorphic LSD1 mice. Cell Research.
Crossref
Qian Li, Lei Shi, Bin Gui, Wenhua Yu, Jiamu Wang, Di Zhang, Xiao Han, Zhi Yao & Yongfeng Shang. (2011) Binding of the JmjC Demethylase JARID1B to LSD1/NuRD Suppresses Angiogenesis and Metastasis in Breast Cancer Cells by Repressing Chemokine CCL14. Cancer Research 71:21, pages 6899-6908.
Crossref
M. M. Singh, C. A. Manton, K. P. Bhat, W.-W. Tsai, K. Aldape, M. C. Barton & J. Chandra. (2011) Inhibition of LSD1 sensitizes glioblastoma cells to histone deacetylase inhibitors. Neuro-Oncology 13:8, pages 894-903.
Crossref
Zoya Marinova, Yan Leng, Peter Leeds & De-Maw Chuang. (2011) Histone deacetylase inhibition alters histone methylation associated with heat shock protein 70 promoter modifications in astrocytes and neurons. Neuropharmacology 60:7-8, pages 1109-1115.
Crossref
Chun-Wei Yu, Xuncheng Liu, Ming Luo, Chiayang Chen, Xiaodong Lin, Gang Tian, Qing Lu, Yuhai Cui & Keqiang Wu. (2011) HISTONE DEACETYLASE6 Interacts with FLOWERING LOCUS D and Regulates Flowering in Arabidopsis      . Plant Physiology 156:1, pages 173-184.
Crossref
Silvia Consalvi, Valentina Saccone, Lorenzo Giordani, Giulia Minetti, Chiara Mozzetta & Pier Lorenzo Puri. (2011) Histone Deacetylase Inhibitors in the Treatment of Muscular Dystrophies: Epigenetic Drugs for Genetic Diseases. Molecular Medicine 17:5-6, pages 457-465.
Crossref
Johannes Gräff, Dohoon Kim, Matthew M. Dobbin & Li-Huei Tsai. (2011) Epigenetic Regulation of Gene Expression in Physiological and Pathological Brain Processes. Physiological Reviews 91:2, pages 603-649.
Crossref
Todd S. Macfarlan, Wesley D. Gifford, Saurabh Agarwal, Shawn Driscoll, Karen Lettieri, Jianxun Wang, Shane E. Andrews, Laura Franco, Michael G. Rosenfeld, Bing Ren & Samuel L. Pfaff. (2011) Endogenous retroviruses and neighboring genes are coordinately repressed by LSD1/KDM1A. Genes & Development 25:6, pages 594-607.
Crossref
Brenda J. Curtis, Claudia B. Zraly, Daniel R. Marenda & Andrew K. Dingwall. (2011) Histone lysine demethylases function as co-repressors of SWI/SNF remodeling activities during Drosophila wing development. Developmental Biology 350:2, pages 534-547.
Crossref
Claudia P. Miller, Melissa M. Singh, Nilsa Rivera-Del Valle, Christa A. Manton & Joya Chandra. (2011) Therapeutic Strategies to Enhance the Anticancer Efficacy of Histone Deacetylase Inhibitors. Journal of Biomedicine and Biotechnology 2011, pages 1-17.
Crossref
Po-Hsien Huang, Chun-Han Chen, Chih-Chien Chou, Aaron M. Sargeant, Samuel K. Kulp, Che-Ming Teng, John C. Byrd & Ching-Shih Chen. (2011) Histone Deacetylase Inhibitors Stimulate Histone H3 Lysine 4 Methylation in Part Via Transcriptional Repression of Histone H3 Lysine 4 Demethylases. Molecular Pharmacology 79:1, pages 197-206.
Crossref
A. Izzo & R. Schneider. (2011) Chatting histone modifications in mammals. Briefings in Functional Genomics 9:5-6, pages 429-443.
Crossref
Haifeng Hou & Hongtao Yu. (2010) Structural insights into histone lysine demethylation. Current Opinion in Structural Biology 20:6, pages 739-748.
Crossref
Lizcano Fernando, Romero Carolina & Diana Vargas. (2010) Regulation of adipogenesis by nucelar receptor PPARγ is modulated by the histone demethylase JMJD2C. Genetics and Molecular Biology 34:1, pages 19-24.
Crossref
Maren Godmann, Erin May & Sarah Kimmins. (2010) Epigenetic Mechanisms Regulate Stem Cell Expressed Genes Pou5f1 and Gfra1 in a Male Germ Cell Line. PLoS ONE 5:9, pages e12727.
Crossref
Li-Ting Chen, Ming Luo, Yu-Yuan Wang & Keqiang Wu. (2010) Involvement of Arabidopsis histone deacetylase HDA6 in ABA and salt stress response. Journal of Experimental Botany 61:12, pages 3345-3353.
Crossref
Nima MosammaparastYang Shi. (2010) Reversal of Histone Methylation: Biochemical and Molecular Mechanisms of Histone Demethylases. Annual Review of Biochemistry 79:1, pages 155-179.
Crossref
Curtis Balch, Daniela E Matei, Tim H-M Huang & Kenneth P Nephew. (2010) Role of epigenomics in ovarian and endometrial cancers. Epigenomics 2:3, pages 419-447.
Crossref
Christopher WynderLeanne Stalker & Martin L Doughty. (2010) Role of H3K4 demethylases in complex neurodevelopmental diseases. Epigenomics 2:3, pages 407-418.
Crossref
Hanna E. Suikki, Paula M. Kujala, Teuvo L.J. Tammela, Wytske M. van Weerden, Robert L. Vessella & Tapio Visakorpi. (2010) Genetic alterations and changes in expression of histone demethylases in prostate cancer. The Prostate 70:8, pages 889-898.
Crossref
Gen-Bao SHAO, Xiao-Jia HUANG, Ai-Hua GONG, Zhi-Jian ZHANG, Rong-Zhu LU & Jian-Rong SANG. (2010) Histone demethylase LSD1 and its biological functions. Hereditas (Beijing) 32:4, pages 331-338.
Crossref
Ze Yang, Jun Jiang, David M Stewart, Shankang Qi, Kenichi Yamane, Jiwen Li, Yi Zhang & Jiemin Wong. (2010) AOF1 is a histone H3K4 demethylase possessing demethylase activity-independent repression function. Cell Research 20:3, pages 276-287.
Crossref
Mario A. Martinez-DiazLimei CheMarcelo AlbornozMarcelo M. SenedaDaryn CollisAna Rita S. CoutinhoNayala El-BeirouthiDenyse LaurinXin ZhaoVilceu Bordignon. (2010) Pre- and Postimplantation Development of Swine-Cloned Embryos Derived from Fibroblasts and Bone Marrow Cells after Inhibition of Histone Deacetylases. Cellular Reprogramming 12:1, pages 85-94.
Crossref
Rabih Murr. 2010. Epigenetics and Cancer, Part A. Epigenetics and Cancer, Part A 101 141 .
Yi Luo, Wei Jian, Diana Stavreva, Xueqi Fu, Gordon Hager, Jörg Bungert, Suming Huang & Yi Qiu. (2009) Trans-regulation of Histone Deacetylase Activities through Acetylation. Journal of Biological Chemistry 284:50, pages 34901-34910.
Crossref
Bryan M. Turner. (2009) Epigenetic responses to environmental change and their evolutionary implications. Philosophical Transactions of the Royal Society B: Biological Sciences 364:1534, pages 3403-3418.
Crossref
Astrid Spannhoff, Alexander-Thomas Hauser, Ralf Heinke, Wolfgang Sippl & Manfred Jung. (2009) The Emerging Therapeutic Potential of Histone Methyltransferase and Demethylase Inhibitors. ChemMedChem 4:10, pages 1568-1582.
Crossref
Danhua Jiang, Xiaofeng Gu & Yuehui He. (2009) Establishment of the Winter-Annual Growth Habit via FRIGIDA -Mediated Histone Methylation at FLOWERING LOCUS C in Arabidopsis   . The Plant Cell 21:6, pages 1733-1746.
Crossref
Federico Forneris, Elena Battaglioli, Andrea Mattevi & Claudia Binda. (2009) New roles of flavoproteins in molecular cell biology: Histone demethylase LSD1 and chromatin. FEBS Journal 276:16, pages 4304-4312.
Crossref
Yan Wang, Hua Zhang, Yupeng Chen, Yimin Sun, Fen Yang, Wenhua Yu, Jing Liang, Luyang Sun, Xiaohan Yang, Lei Shi, Ruifang Li, Yanyan Li, Yu Zhang, Qian Li, Xia Yi & Yongfeng Shang. (2009) LSD1 Is a Subunit of the NuRD Complex and Targets the Metastasis Programs in Breast Cancer. Cell 138:4, pages 660-672.
Crossref
Xin Hu, Xingguo Li, Kristell Valverde, Xueqi Fu, Constance Noguchi, Yi QiuSuming Huang. (2009) LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis. Proceedings of the National Academy of Sciences 106:25, pages 10141-10146.
Crossref
Gee Y. Ching & Ronald K. H. Liem. (2009) RE1 silencing transcription factor is involved in regulating neuron-specific expression of α-internexin and neurofilament genes. Journal of Neurochemistry 109:6, pages 1610-1623.
Crossref
Connie C. Cortez & Peter A. Jones. (2008) Chromatin, cancer and drug therapies. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 647:1-2, pages 44-51.
Crossref
Christian B. Gocke & Hongtao Yu. (2008) ZNF198 Stabilizes the LSD1–CoREST–HDAC1 Complex on Chromatin through Its MYM-Type Zinc Fingers. PLoS ONE 3:9, pages e3255.
Crossref
Lezanne OoiIan C. Wood. (2008) Chromatin switching and transcriptional regulation in disease. Biochemical Society Transactions 36:4, pages 599-602.
Crossref
Donald R. Walkinshaw, Soroush Tahmasebi, Nicholas R. Bertos & Xiang-Jiao Yang. (2008) Histone deacetylases as transducers and targets of nuclear signaling. Journal of Cellular Biochemistry 104:5, pages 1541-1552.
Crossref
Marcelo M Seneda, Maren Godmann, Bruce D Murphy, Sarah Kimmins & Vilceu Bordignon. (2008) Developmental regulation of histone H3 methylation at lysine 4 in the porcine ovary. REPRODUCTION 135:6, pages 829-838.
Crossref
Fei Lan, Amanda Clair Nottke & Yang Shi. (2008) Mechanisms involved in the regulation of histone lysine demethylases. Current Opinion in Cell Biology 20:3, pages 316-325.
Crossref
Veiko Krauss. (2007) Glimpses of evolution: heterochromatic histone H3K9 methyltransferases left its marks behind. Genetica 133:1, pages 93-106.
Crossref
Valentina Spedaletti, Fabio Polticelli, Viviana Capodaglio, M. Eugenia Schininà, Pasquale Stano, Rodolfo Federico & Paraskevi Tavladoraki. (2008) Characterization of a Lysine-Specific Histone Demethylase from Arabidopsis thaliana. Biochemistry 47:17, pages 4936-4947.
Crossref
Federico Forneris, Claudia Binda, Elena Battaglioli & Andrea Mattevi. (2008) LSD1: oxidative chemistry for multifaceted functions in chromatin regulation. Trends in Biochemical Sciences 33:4, pages 181-189.
Crossref
Xiang-Jiao Yang & Edward Seto. (2008) The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men. Nature Reviews Molecular Cell Biology 9:3, pages 206-218.
Crossref
Stephen D. Nimer. (2008) Is it important to decipher the heterogeneity of “normal karyotype AML”?. Best Practice & Research Clinical Haematology 21:1, pages 43-52.
Crossref
Jing Bo Jin, Yin Hua Jin, Jiyoung Lee, Kenji Miura, Chan Yul Yoo, Woe-Yeon Kim, Michael Van Oosten, Youbong Hyun, David E. Somers, Ilha Lee, Dae-Jin Yun, Ray A. Bressan & Paul M. Hasegawa. (2007) The SUMO E3 ligase, AtSIZ1, regulates flowering by controlling a salicylic acid-mediated floral promotion pathway and through affects on FLC chromatin structure. The Plant Journal 53:3, pages 530-540.
Crossref
Ana Lázaro, Ángeles Gómez-Zambrano, Leticia López-González, Manuel Piñeiro & Jose A. Jarillo. (2008) Mutations in the Arabidopsis SWC6 gene, encoding a component of the SWR1 chromatin remodelling complex, accelerate flowering time and alter leaf and flower development . Journal of Experimental Botany 59:3, pages 653-666.
Crossref
Qingjun Zhu, Cheng Liu, Zheng Ge, Xiaolei Fang, Xi Zhang, Klas Strååt, Magnus Björkholm & Dawei Xu. (2008) Lysine-Specific Demethylase 1 (LSD1) Is Required for the Transcriptional Repression of the Telomerase Reverse Transcriptase (hTERT) Gene. PLoS ONE 3:1, pages e1446.
Crossref
Danhua Jiang, Wannian Yang, Yuehui He & Richard M. Amasino. (2007) Arabidopsis Relatives of the Human Lysine-Specific Demethylase1 Repress the Expression of FWA and FLOWERING LOCUS C and Thus Promote the Floral Transition . The Plant Cell 19:10, pages 2975-2987.
Crossref
Hai-tao Zhang, Zhe-ling Feng, Jun Wu, Ya-jun Wang, Xia Guo, Nian-ci Liang, Zhen-yu Zhu & Jian-quan Ma. (2007) Sodium butyrate-induced death-associated protein kinase expression promote Raji cell morphological change and apoptosis by reducing FAK protein levels. Acta Pharmacologica Sinica 28:11, pages 1783-1790.
Crossref
Maren Godmann, Veronik Auger, Vivian Ferraroni-Aguiar, Annarita Di Sauro, Claudio Sette, Ruediger Behr & Sarah Kimmins. (2007) Dynamic Regulation of Histone H3 Methylation at Lysine 4 in Mammalian Spermatogenesis1. Biology of Reproduction 77:5, pages 754-764.
Crossref
John A Latham & Sharon Y R Dent. (2007) Cross-regulation of histone modifications. Nature Structural & Molecular Biology 14:11, pages 1017-1024.
Crossref
Fuquan Liu, Victor Quesada, Pedro Crevillén, Isabel Bäurle, Szymon Swiezewski & Caroline Dean. (2007) The Arabidopsis RNA-Binding Protein FCA Requires a Lysine-Specific Demethylase 1 Homolog to Downregulate FLC. Molecular Cell 28:3, pages 398-407.
Crossref
K L Rice, I Hormaeche & J D Licht. (2007) Epigenetic regulation of normal and malignant hematopoiesis. Oncogene 26:47, pages 6697-6714.
Crossref
Maojun Yang, Jeffrey C Culhane, Lawrence M Szewczuk, Christian B Gocke, Chad A Brautigam, Diana R Tomchick, Mischa Machius, Philip A Cole & Hongtao Yu. (2007) Structural basis of histone demethylation by LSD1 revealed by suicide inactivation. Nature Structural & Molecular Biology 14:6, pages 535-539.
Crossref
Wen Chen, Masanobu Obara, Yuji Ishida, Ken-ichi Suzuki & Katsutoshi Yoshizato. (2007) Characterization of histone lysine-specific demethylase in relation to thyroid hormone-regulated anuran metamorphosis. Development, Growth & Differentiation 49:4, pages 325-334.
Crossref
Robert J. Schmitz & Richard M. Amasino. (2007) Vernalization: A model for investigating epigenetics and eukaryotic gene regulation in plants. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 1769:5-6, pages 269-275.
Crossref
Michael Opel, David Lando, Carolina Bonilla, Sarah C. Trewick, Abdelhalim Boukaba, Julian Walfridsson, James Cauwood, Petra J.H. Werler, Antony M. Carr, Tony Kouzarides, Natalia V. Murzina, Robin C. Allshire, Karl Ekwall & Ernest D. Laue. (2007) Genome-Wide Studies of Histone Demethylation Catalysed by the Fission Yeast Homologues of Mammalian LSD1. PLoS ONE 2:4, pages e386.
Crossref
Robert J. Klose & Yi Zhang. (2007) Regulation of histone methylation by demethylimination and demethylation. Nature Reviews Molecular Cell Biology 8:4, pages 307-318.
Crossref
Thomas Rudolph, Masato Yonezawa, Sandro Lein, Kathleen Heidrich, Stefan Kubicek, Christiane Schäfer, Sameer Phalke, Matthias Walther, Andreas Schmidt, Thomas Jenuwein & Gunter Reuter. (2007) Heterochromatin Formation in Drosophila Is Initiated through Active Removal of H3K4 Methylation by the LSD1 Homolog SU(VAR)3-3. Molecular Cell 26:1, pages 103-115.
Crossref
Fei Lan, Mikel Zaratiegui, Judit Villén, Matthew W. Vaughn, André Verdel, Maite Huarte, Yujiang Shi, Steven P. Gygi, Danesh Moazed, Robert A. Martienssen & Yang Shi. (2007) S. pombe LSD1 Homologs Regulate Heterochromatin Propagation and Euchromatic Gene Transcription. Molecular Cell 26:1, pages 89-101.
Crossref
Min Gyu Lee, Jessica Norman, Ali Shilatifard & Ramin Shiekhattar. (2007) Physical and Functional Association of a Trimethyl H3K4 Demethylase and Ring6a/MBLR, a Polycomb-like Protein. Cell 128:5, pages 877-887.
Crossref
Xiaoqing Tian & Jingyuan Fang. (2007) Current Perspectives on Histone Demethylases. Acta Biochimica et Biophysica Sinica 39:2, pages 81-88.
Crossref
G. Chinnadurai. (2007) Transcriptional regulation by C-terminal binding proteins. The International Journal of Biochemistry & Cell Biology 39:9, pages 1593-1607.
Crossref

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