82
Views
92
CrossRef citations to date
0
Altmetric
Article

Rac1 Activation in Podocytes Induces Rapid Foot Process Effacement and Proteinuria

, , , , , & show all
Pages 4755-4764 | Received 12 Jun 2013, Accepted 18 Sep 2013, Published online: 20 Mar 2023

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Clara Steichen, Claude Hervé, Thierry Hauet & Nicolas Bourmeyster. (2022) Rho GTPases in kidney physiology and diseases. Small GTPases 13:1, pages 141-161.
Read now
David Auguste, Mirela Maier, Cindy Baldwin, Lamine Aoudjit, Richard Robins, Indra R. Gupta & Tomoko Takano. (2016) Disease-causing mutations of RhoGDIα induce Rac1 hyperactivation in podocytes. Small GTPases 7:2, pages 107-121.
Read now
Mélanie Laurin, Annie Dumouchel, Yoshinori Fukui & Jean-François Côté. (2013) The Rac-specific exchange factors Dock1 and Dock5 are dispensable for the establishment of the glomerular filtration barrier in vivo. Small GTPases 4:4, pages 221-230.
Read now

Articles from other publishers (89)

Onur K. Polat, Elena Isaeva, Yashwanth R. Sudhini, Brenna Knott, Ke Zhu, Manuel Noben, Varsha Suresh Kumar, Nicole Endlich, Steve Mangos, Tejasree Vallapu Reddy, Beata Samelko, Changli Wei, Mehmet M. Altintas, Stuart E. Dryer, Sanja Sever, Alexander Staruschenko & Jochen Reiser. (2023) The small GTPase regulatory protein Rac1 drives podocyte injury independent of cationic channel protein TRPC5. Kidney International 103:6, pages 1056-1062.
Crossref
Wataru Fujii & Shigeru Shibata. (2023) Mineralocorticoid Receptor Antagonists for Preventing Chronic Kidney Disease Progression: Current Evidence and Future Challenges. International Journal of Molecular Sciences 24:9, pages 7719.
Crossref
Roberto Boi, Lovisa Bergwall, Kerstin Ebefors, Martin O. Bergö, Jenny Nyström & Lisa Buvall. (2023) Podocyte Geranylgeranyl Transferase Type-I Is Essential for Maintenance of the Glomerular Filtration Barrier. Journal of the American Society of Nephrology 34:4, pages 641-655.
Crossref
Jun Matsuda, Dina Greenberg, Sajida Ibrahim, Mirela Maier, Lamine Aoudjit, Jennifer Chapelle, Cindy Baldwin, Yi He, Nathalie Lamarche-Vane & Tomoko Takano. (2022) CdGAP maintains podocyte function and modulates focal adhesions in a Src kinase-dependent manner. Scientific Reports 12:1.
Crossref
William J. Mason, Daniyal J. Jafree, Gideon Pomeranz, Maria Kolatsi-Joannou, Antje K. Rottner, Sabrina Pacheco, Dale A. Moulding, Anja Wolf, Christian Kupatt, Claire Peppiatt-Wildman, Eugenia Papakrivopoulou, Paul R. Riley, David A. Long & Elisavet Vasilopoulou. (2022) Systemic gene therapy with thymosin β4 alleviates glomerular injury in mice. Scientific Reports 12:1.
Crossref
Maurizio Salvadori & Aris Tsalouchos. (2021) How immunosuppressive drugs may directly target podocytes in glomerular diseases. Pediatric Nephrology 37:7, pages 1431-1441.
Crossref
Federica Barutta, Stefania Bellini & Gabriella Gruden. (2022) Mechanisms of podocyte injury and implications for diabetic nephropathy. Clinical Science 136:7, pages 493-520.
Crossref
Manuel Rogg, Jasmin I. Maier, Markus Ehle, Alena Sammarco, Oliver Schilling, Martin Werner & Christoph Schell. (2022) NUP133 Controls Nuclear Pore Assembly, Transcriptome Composition, and Cytoskeleton Regulation in Podocytes. Cells 11:8, pages 1259.
Crossref
Sipan Zhang, Junnan Wu, Xiaodong Zhu, Hui Song, Lu Ren, Qiaoli Tang, Xiaodong Xu, Chunbei Liu, Jiong Zhang, Weixin Hu, Zhihong Liu & Shaolin Shi. (2021) A novel approach to identify the mechanism of miR-145-5p toxicity to podocytes based on the essential genes targeting analysis. Molecular Therapy - Nucleic Acids 26, pages 749-759.
Crossref
Fehime K. Eroglu, Volkan Yazar, Ulku Guler, Muzaffer Yıldırım, Tugce Yildirim, Tulin Gungor, Evra Celikkaya, Deniz Karakaya, Nilsu Turay, Eda Ciftci Dede, Petek Korkusuz, Bekir Salih, Mehmet Bulbul & Ihsan Gursel. (2021) Circulating extracellular vesicles of patients with steroid-sensitive nephrotic syndrome have higher RAC1 and induce recapitulation of nephrotic syndrome phenotype in podocytes. American Journal of Physiology-Renal Physiology 321:5, pages F659-F673.
Crossref
Ilse S. Daehn & Jeremy S. Duffield. (2021) The glomerular filtration barrier: a structural target for novel kidney therapies. Nature Reviews Drug Discovery 20:10, pages 770-788.
Crossref
Yiming Zhou, Choah Kim, Juan Lorenzo B. Pablo, Fan Zhang, Ji Yong Jung, Li Xiao, Silvana Bazua-Valenti, Maheswarareddy Emani, Corey R. Hopkins, Astrid Weins & Anna Greka. (2021) TRPC5 Channel Inhibition Protects Podocytes in Puromycin-Aminonucleoside Induced Nephrosis Models. Frontiers in Medicine 8.
Crossref
Changjiang Ying, Jiao Dai, Gaoxia Fan, Zhongyuan Zhou, Tian Gan, Yusheng Zhang, Yuanjian Song & Xiaoyan Zhou. (2021) Ras-Related C3 Botulinum Toxin Substrate 1 Combining With the Mixed Lineage Kinase 3- Mitogen-Activated Protein Kinase 7- c-Jun N-Terminal Kinase Signaling Module Accelerates Diabetic Nephropathy. Frontiers in Physiology 12.
Crossref
Irena Audzeyenka, Dorota Rogacka, Patrycja Rachubik, Marlena Typiak, Michał Rychłowski, Stefan Angielski & Agnieszka Piwkowska. (2020) The PKGIα–Rac1 pathway is a novel regulator of insulin‐dependent glucose uptake in cultured rat podocytes. Journal of Cellular Physiology 236:6, pages 4655-4668.
Crossref
Kana Asano-Matsuda, Sajida Ibrahim, Tomoko Takano & Jun Matsuda. (2021) Role of Rho GTPase Interacting Proteins in Subcellular Compartments of Podocytes. International Journal of Molecular Sciences 22:7, pages 3656.
Crossref
Manuel Rogg, Jasmin I. Maier, Robert Dotzauer, Nadine Artelt, Oliver Kretz, Martin Helmstädter, Ahmed Abed, Alena Sammarco, August Sigle, Dominik Sellung, Patrick Dinse, Karoline Reiche, Mako Yasuda-Yamahara, Martin L. Biniossek, Gerd Walz, Martin Werner, Nicole Endlich, Oliver Schilling, Tobias B. Huber & Christoph Schell. (2021) SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance. Journal of the American Society of Nephrology 32:3, pages 563-579.
Crossref
Jun Matsuda, Kana Asano-Matsuda, Thomas M. Kitzler & Tomoko Takano. (2021) Rho GTPase regulatory proteins in podocytes. Kidney International 99:2, pages 336-345.
Crossref
Wen Shen, Mohammed Alshehri, Sameer Desale & Christopher Wilcox. (2021) The Effect of Amiloride on Proteinuria in Patients with Proteinuric Kidney Disease. American Journal of Nephrology 52:5, pages 368-377.
Crossref
Amar J. Majmundar, Florian Buerger, Thomas A. Forbes, Verena KlämbtRonen Schneider, Konstantin Deutsch, Thomas M. KitzlerSara E. HowdenMichelle ScurrKer Sin TanMickaël KrzeminskiEugen Widmeier, Daniela A. BraunEthan LaiIhsan Ullah, Ali Amar, Amy Kolb, Kaitlyn EddyChin Heng ChenDaanya Salmanullah, Rufeng DaiMakiko NakayamaIsabel OttlewskiCaroline M. Kolvenbach, Ana C. Onuchic-Whitford, Youying MaoNina MannMarwa M. NabhanSeymour RosenJulie D. Forman-Kay, Neveen A. Soliman, Andreas HeilosRenate Kain, Christoph AufrichtShrikant Mane, Richard P. LiftonShirlee Shril, Melissa H. Little & Friedhelm Hildebrandt. (2021) Recessive NOS1AP variants impair actin remodeling and cause glomerulopathy in humans and mice . Science Advances 7:1.
Crossref
Manuel Alfredo Podestà & Claudio Ponticelli. (2020) Autoimmunity in Focal Segmental Glomerulosclerosis: A Long-Standing Yet Elusive Association. Frontiers in Medicine 7.
Crossref
Jun Matsuda, Mirela Maier, Lamine Aoudjit, Cindy Baldwin & Tomoko Takano. (2020) ARHGEF7 (β-PIX) Is Required for the Maintenance of Podocyte Architecture and Glomerular Function. Journal of the American Society of Nephrology 31:5, pages 996-1008.
Crossref
Igor Kravets & Sandeep K Mallipattu. (2020) The Role of Podocytes and Podocyte-Associated Biomarkers in Diagnosis and Treatment of Diabetic Kidney Disease. Journal of the Endocrine Society 4:4.
Crossref
Ya. F. Zverev & A. Ya. Rykunova. (2020) Several reasons for the development of proteinuria in nephrotic syndrome. Nephrology (Saint-Petersburg) 24:1, pages 9-21.
Crossref
Gentzon Hall, Liming Wang & Robert F. Spurney. (2019) TRPC Channels in Proteinuric Kidney Diseases. Cells 9:1, pages 44.
Crossref
Juan Lorenzo Pablo & Anna Greka. (2019) Charting a TRP to Novel Therapeutic Destinations for Kidney Diseases. Trends in Pharmacological Sciences 40:12, pages 911-918.
Crossref
Maolin Yu, Mark W. Ledeboer, Matthew Daniels, Goran Malojcic, Thomas T. Tibbitts, Marie Coeffet-Le Gal, Xin-Ru Pan-Zhou, Amy Westerling-Bui, Maria Beconi, John F. Reilly, Peter Mundel & Jean-Christophe Harmange. (2019) Discovery of a Potent and Selective TRPC5 Inhibitor, Efficacious in a Focal Segmental Glomerulosclerosis Model. ACS Medicinal Chemistry Letters 10:11, pages 1579-1585.
Crossref
Raphael J. F. Felizardo, Danilo C. Almeida, Rafael L. Pereira, Ingrid K. M. Watanabe, Nayara T. S. Doimo, Willian R. Ribeiro, Marcos A. Cenedeze, Meire I. Hiyane, Mariane T. Amano, Tárcio T. Braga, Caroline M. Ferreira, Raphael B. Parmigiani, Vinicius Andrade‐Oliveira, Rildo A. Volpini, Marco Aurélio R. Vinolo, Eliana Mariño, Remy Robert, Charles R. Mackay & Niels O. S. Camara. (2019) Gut microbial metabolite butyrate protects against proteinuric kidney disease through epigenetic‐ and GPR109a‐mediated mechanisms. The FASEB Journal 33:11, pages 11894-11908.
Crossref
Dong Yeon Kim, Min‐Kyung Kang, Yun‐Ho Kim, Eun‐Jung Lee, Hyeongjoo Oh, Soo‐Il Kim, Su Yeon Oh & Young‐Hee Kang. (2019) Eucalyptol Ameliorates Dysfunction of Actin Cytoskeleton Formation and Focal Adhesion Assembly in Glucose‐Loaded Podocytes and Diabetic Kidney. Molecular Nutrition & Food Research 63:22, pages 1900489.
Crossref
Ehtesham Arif, Ashish K. Solanki, Pankaj Srivastava, Bushra Rahman, Brian R. Tash, Lawrence B. Holzman, Michael G. Janech, René Martin, Hans-Joachim Knölker, Wayne R. Fitzgibbon, Peifeng Deng, Milos N. Budisavljevic, Wing-Kin Syn, Cindy Wang, Joshua H. Lipschutz, Sang-Ho Kwon & Deepak Nihalani. (2019) The motor protein Myo1c regulates transforming growth factor-β–signaling and fibrosis in podocytes. Kidney International 96:1, pages 139-158.
Crossref
Konstantinos Koutroutsos, Rawya Charif, Linda Moran, Jill Moss, Terence Cook, Candice Roufosse, Charles Pusey, David Taube & Marina Loucaidou. (2019) Successful management of post-transplant focal segmental glomerulosclerosis with therapeutic plasma exchange and rituximab. Clinical and Experimental Nephrology 23:5, pages 700-709.
Crossref
Szu-Yuan Li, Pao-Hsien Chu, Po-Hsun Huang, Tsung-Han Hsieh, Katalin Susztak & Der-Cherng Tarng. (2019) FHL2 mediates podocyte Rac1 activation and foot process effacement in hypertensive nephropathy. Scientific Reports 9:1.
Crossref
Moin A. Saleem & Gavin I. Welsh. (2019) Podocyte RhoGTPases: new therapeutic targets for nephrotic syndrome?. F1000Research 8, pages 1847.
Crossref
Samuel Mon-Wei Yu, Pitchaphon Nissaisorakarn, Irma Husain & Belinda Jim. (2018) Proteinuric Kidney Diseases: A Podocyte's Slit Diaphragm and Cytoskeleton Approach. Frontiers in Medicine 5.
Crossref
Kayaho Maeda, Kotaro Otomo, Nobuya Yoshida, Mones S. Abu-Asab, Kunihiro Ichinose, Tomoya Nishino, Michihito Kono, Andrew Ferretti, Rhea Bhargava, Shoichi Maruyama, Sean Bickerton, Tarek M. Fahmy, Maria G. Tsokos & George C. Tsokos. (2018) CaMK4 compromises podocyte function in autoimmune and nonautoimmune kidney disease. Journal of Clinical Investigation 128:8, pages 3445-3459.
Crossref
Mako Yasuda-Yamahara, Manuel Rogg, Kosuke Yamahara, Jasmin I. Maier, Tobias B. Huber & Christoph Schell. (2018) AIF1L regulates actomyosin contractility and filopodial extensions in human podocytes. PLOS ONE 13:7, pages e0200487.
Crossref
Florian Siegerist, Karlhans Endlich & Nicole Endlich. (2018) Novel Microscopic Techniques for Podocyte Research. Frontiers in Endocrinology 9.
Crossref
Agnès Jamin, Laureline Berthelot, Anne Couderc, Jonathan M. Chemouny, Erwan Boedec, Laurène Dehoux, Lilia Abbad, Claire Dossier, Eric Daugas, Renato C. Monteiro & Georges Deschênes. (2018) Autoantibodies against podocytic UCHL1 are associated with idiopathic nephrotic syndrome relapses and induce proteinuria in mice. Journal of Autoimmunity 89, pages 149-161.
Crossref
Rin Asao, Takuto Seki, Miyuki Takagi, Hiroyuki Yamada, Fumiko Kodama, Yoshiko Hosoe-Nagai, Eriko Tanaka, Juan Alejandro Oliva Trejo, Kanae Yamamoto-Nonaka, Yu Sasaki, Teruo Hidaka, Takashi Ueno, Motoko Yanagita, Yusuke Suzuki, Yasuhiko Tomino & Katsuhiko Asanuma. (2018) Rac1 in podocytes promotes glomerular repair and limits the formation of sclerosis. Scientific Reports 8:1.
Crossref
Samuel Mon-Wei Yu & Joseph V. Bonventre. (2018) Acute Kidney Injury and Progression of Diabetic Kidney Disease. Advances in Chronic Kidney Disease 25:2, pages 166-180.
Crossref
Cristina I. Øie, Viola Mönkemöller, Wolfgang Hübner, Mark Schüttpelz, Hong Mao, Balpreet S. Ahluwalia, Thomas R. Huser & Peter McCourt. (2018) New ways of looking at very small holes – using optical nanoscopy to visualize liver sinusoidal endothelial cell fenestrations. Nanophotonics 7:3, pages 575-596.
Crossref
Mirela Maier, Cindy Baldwin, Lamine Aoudjit & Tomoko Takano. (2018) The Role of Trio, a Rho Guanine Nucleotide Exchange Factor, in Glomerular Podocytes. International Journal of Molecular Sciences 19:2, pages 479.
Crossref
Yulu Cherry Liu & Justin Chun. (2018) Prospects for Precision Medicine in Glomerulonephritis Treatment. Canadian Journal of Kidney Health and Disease 5, pages 205435811775361.
Crossref
Jun-Jae ChungAndrey S. Shaw. (2017) TRP'ing up chronic kidney disease. Science 358:6368, pages 1256-1257.
Crossref
Ying Sun, Chen Guo, Ping Ma, Yumei Lai, Fan Yang, Jun Cai, Zhehao Cheng, Kuo Zhang, Zhongzhen Liu, Yeteng Tian, Yue Sheng, Ruijun Tian, Yi Deng, Guozhi Xiao & Chuanyue Wu. (2017) Kindlin-2 Association with Rho GDP-Dissociation Inhibitor α Suppresses Rac1 Activation and Podocyte Injury. Journal of the American Society of Nephrology 28:12, pages 3545-3562.
Crossref
Alfred H.J. Kim, Jun-Jae Chung, Shreeram Akilesh, Ania Koziell, Sanjay Jain, Jeffrey B. Hodgin, Mark J. Miller, Thaddeus S. Stappenbeck, Jeffrey H. Miner & Andrey S. Shaw. (2017) B cell–derived IL-4 acts on podocytes to induce proteinuria and foot process effacement. JCI Insight 2:21.
Crossref
Christoph Schell & Tobias B. Huber. (2017) The Evolving Complexity of the Podocyte Cytoskeleton. Journal of the American Society of Nephrology 28:11, pages 3166-3174.
Crossref
Jamie S. Lin, Jin Seok Jeon, Qingfeng Fan, Hetty N. Wong, Matthew B. Palmer & Lawrence B. Holzman. (2017) ARF6 mediates nephrin tyrosine phosphorylation-induced podocyte cellular dynamics. PLOS ONE 12:9, pages e0184575.
Crossref
Hani Y. Suleiman, Robyn Roth, Sanjay Jain, John E. Heuser, Andrey S. Shaw & Jeffrey H. Miner. (2017) Injury-induced actin cytoskeleton reorganization in podocytes revealed by super-resolution microscopy. JCI Insight 2:16.
Crossref
Richard Robins, Cindy Baldwin, Lamine Aoudjit, Jean-François Côté, Indra R. Gupta & Tomoko Takano. (2017) Rac1 activation in podocytes induces the spectrum of nephrotic syndrome. Kidney International 92:2, pages 349-364.
Crossref
Nicole Endlich, Florian Siegerist & Karlhans Endlich. (2017) Are podocytes motile?. Pflügers Archiv - European Journal of Physiology 469:7-8, pages 951-957.
Crossref
Christoph SchellManuel RoggMartina SuhmMartin HelmstädterDominik SellungMako Yasuda-YamaharaOliver KretzVictoria KüttnerHani SuleimanLaxmikanth KolliparaRené P. ZahediAlbert SickmannStefan EimerAndrey S. ShawAlbrecht Kramer-ZuckerMariko Hirano-KobayashiTakaya AbeShinichi AizawaFlorian GrahammerBjörn HartlebenJörn Dengjel & Tobias B. Huber. (2017) The FERM protein EPB41L5 regulates actomyosin contractility and focal adhesion formation to maintain the kidney filtration barrier. Proceedings of the National Academy of Sciences 114:23.
Crossref
Suheir Assady, Nicola Wanner, Karl L. Skorecki & Tobias B. Huber. (2017) New Insights into Podocyte Biology in Glomerular Health and Disease. Journal of the American Society of Nephrology 28:6, pages 1707-1715.
Crossref
Markus M. Rinschen, Florian GrahammerAnn-Kathrin Hoppe, Priyanka KohliHenning Hagmann, Oliver KretzSabine BertschMartin Höhne, Heike GöbelMalte P. BartramRajesh Kumar GandhirajanMarcus KrügerPaul-Thomas BrinkkoetterTobias B. HuberMartin KannSara A. Wickström, Thomas Benzing & Bernhard Schermer. (2017) YAP-mediated mechanotransduction determines the podocyte’s response to damage. Science Signaling 10:474.
Crossref
Cibele V. Falkenberg, Evren U. Azeloglu, Mark Stothers, Thomas J. Deerinck, Yibang Chen, John C. He, Mark H. Ellisman, James C. Hone, Ravi Iyengar & Leslie M. Loew. (2017) Fragility of foot process morphology in kidney podocytes arises from chaotic spatial propagation of cytoskeletal instability. PLOS Computational Biology 13:3, pages e1005433.
Crossref
Haoran Dai, Qingquan Liu & Baoli Liu. (2017) Research Progress on Mechanism of Podocyte Depletion in Diabetic Nephropathy. Journal of Diabetes Research 2017, pages 1-10.
Crossref
Frances Kindt, Elke Hammer, Stefan Kemnitz, Antje Blumenthal, Paul Klemm, Rabea Schlüter, Susan E Quaggin, Jens van den Brandt, Georg Fuellen, Uwe Völker, Karlhans Endlich & Nicole Endlich. (2017) A novel assay to assess the effect of pharmaceutical compounds on the differentiation of podocytes. British Journal of Pharmacology 174:2, pages 163-176.
Crossref
Eunsil Hahm, Changli Wei, Isabel Fernandez, Jing Li, Nicholas J Tardi, Melissa Tracy, Shikha Wadhwani, Yanxia Cao, Vasil Peev, Andrew Zloza, Jevgenijs Lusciks, Salim S Hayek, Christopher O'Connor, Markus Bitzer, Vineet Gupta, Sanja Sever, David B Sykes, David T Scadden & Jochen Reiser. (2016) Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease. Nature Medicine 23:1, pages 100-106.
Crossref
Yilin Tai, Shenglian Yang, Yong Liu & Wei Shao. 2017. Transient Receptor Potential Canonical Channels and Brain Diseases. Transient Receptor Potential Canonical Channels and Brain Diseases 35 45 .
Chang-Yien Chan, Kar-Hui Ng, Jinmiao Chen, Jinhua Lu, Caroline Guat-Lay Lee, Puay-Hoon Tan, Stanley C. JordanHenry Yang He & Hui-Kim Yap. (2016) Novel role of Vav1-Rac1 pathway in actin cytoskeleton regulation in interleukin-13-induced minimal change-like nephropathy. Clinical Science 130:24, pages 2317-2327.
Crossref
Sebastian Brähler, Haiyang Yu, Hani Suleiman, Gokul M. Krishnan, Brian T. Saunders, Jeffrey B. Kopp, Jeffrey H. Miner, Bernd H. Zinselmeyer & Andrey S. Shaw. (2016) Intravital and Kidney Slice Imaging of Podocyte Membrane Dynamics. Journal of the American Society of Nephrology 27:11, pages 3285-3290.
Crossref
Luca Perico, Sara Conti, Ariela Benigni & Giuseppe Remuzzi. (2016) Podocyte–actin dynamics in health and disease. Nature Reviews Nephrology 12:11, pages 692-710.
Crossref
Sybille Koehler, Sebastian Brähler, Alexander Kuczkowski, Julia Binz, Matthias J. Hackl, Henning Hagmann, Martin Höhne, Merly C. Vogt, Claudia M. Wunderlich, F. Thomas Wunderlich, Frank Schweda, Bernhard Schermer, Thomas Benzing & Paul T. Brinkkoetter. (2016) Single and Transient Ca2+ Peaks in Podocytes do not induce Changes in Glomerular Filtration and Perfusion. Scientific Reports 6:1.
Crossref
Xuefei Tian & Shuta Ishibe. (2016) Targeting the podocyte cytoskeleton: from pathogenesis to therapy in proteinuric kidney disease. Nephrology Dialysis Transplantation 31:10, pages 1577-1583.
Crossref
Xiaoyan Liang, H. William Schnaper, Taiji Matsusaka, Ira Pastan, Steve Ledbetter & Tomoko Hayashida. (2016) Anti-TGF-β Antibody, 1D11, Ameliorates Glomerular Fibrosis in Mouse Models after the Onset of Proteinuria. PLOS ONE 11:5, pages e0155534.
Crossref
Johannes Elvin, Lisa Buvall, Annika Lindskog JonssonAnna GranqvistEmelie LassénLovisa Bergwall, Jenny Nyström & Börje Haraldsson. (2016) Melanocortin 1 receptor agonist protects podocytes through catalase and RhoA activation. American Journal of Physiology-Renal Physiology 310:9, pages F846-F856.
Crossref
Alfred H.J. Kim, Hani Suleiman & Andrey S. Shaw. (2016) New approaches in renal microscopy. Current Opinion in Nephrology and Hypertension 25:3, pages 159-167.
Crossref
Jamie S. Lin & Katalin Susztak. (2016) Podocytes: the Weakest Link in Diabetic Kidney Disease?. Current Diabetes Reports 16:5.
Crossref
Jharna R Das, J. Silvio Gutkind & Patricio E Ray. (2016) Circulating Fibroblast Growth Factor-2, HIV-Tat, and Vascular Endothelial Cell Growth Factor-A in HIV-Infected Children with Renal Disease Activate Rho-A and Src in Cultured Renal Endothelial Cells. PLOS ONE 11:4, pages e0153837.
Crossref
Xiaoyang Wan, Mi-Sun Lee & Weibin Zhou. (2016) Dosage-dependent role of Rac1 in podocyte injury. American Journal of Physiology-Renal Physiology 310:8, pages F777-F784.
Crossref
Mahtab Tavasoli, Laiji Li, Abass Al-Momany, Lin-Fu Zhu, Benjamin A. Adam, Zhixiang Wang & Barbara J. Ballermann. (2016) The chloride intracellular channel 5A stimulates podocyte Rac1, protecting against hypertension-induced glomerular injury. Kidney International 89:4, pages 833-847.
Crossref
Haiyang Yu, Mykyta Artomov, Sebastian Brähler, M. Christine Stander, Ghaidan Shamsan, Matthew G. Sampson, J. Michael White, Matthias Kretzler, Jeffrey H. Miner, Sanjay Jain, Cheryl A. Winkler, Robi D. Mitra, Jeffrey B. Kopp, Mark J. Daly & Andrey S. Shaw. (2016) A role for genetic susceptibility in sporadic focal segmental glomerulosclerosis. Journal of Clinical Investigation 126:3, pages 1067-1078.
Crossref
Katherine Stewart, Yaned Gaitan, Maxwell E. R. Shafer, Lamine Aoudjit, Di Hu, Richa Sharma, Mathieu Tremblay, Hidetaka Ishii, Michael Marcotte, Daniela Stanga, You Chi Tang, Sami Kamel Boualia, Alana H. T. Nguyen, Tomoko Takano, Nathalie Lamarche-Vane, Silvia Vidal & Maxime Bouchard. (2016) A Point Mutation in p190A RhoGAP Affects Ciliogenesis and Leads to Glomerulocystic Kidney Defects. PLOS Genetics 12:2, pages e1005785.
Crossref
David Unnersjö-Jess, Lena Scott, Hans Blom & Hjalmar Brismar. (2016) Super-resolution stimulated emission depletion imaging of slit diaphragm proteins in optically cleared kidney tissue. Kidney International 89:1, pages 243-247.
Crossref
Yuya Sugano, Maja T. Lindenmeyer, Ines Auberger, Urs Ziegler, Stephan Segerer, Clemens D. Cohen, Stephan C.F. Neuhauss & Johannes Loffing. (2015) The Rho-GTPase binding protein IQGAP2 is required for the glomerular filtration barrier. Kidney International 88:5, pages 1047-1056.
Crossref
Sebastian BrählerChristina IsingBelén Barrera ArandaMartin Höhne, Bernhard Schermer, Thomas Benzing & Paul Thomas Brinkkoetter. (2015) The NF-κB essential modulator (NEMO) controls podocyte cytoskeletal dynamics independently of NF-κB. American Journal of Physiology-Renal Physiology 309:7, pages F617-F626.
Crossref
Johannes Schlondorff. (2015) How many Achilles' heels does a podocyte have? An update on podocyte biology: Table 1.. Nephrology Dialysis Transplantation 30:7, pages 1091-1097.
Crossref
Jun-Jae Chung, Tobias B. Huber, Markus Gödel, George Jarad, Björn Hartleben, Christopher Kwoh, Alexander Keil, Aleksey Karpitskiy, Jiancheng Hu, Christine J. Huh, Marina Cella, Richard W. Gross, Jeffrey H. Miner & Andrey S. Shaw. (2015) Albumin-associated free fatty acids induce macropinocytosis in podocytes. Journal of Clinical Investigation 125:6, pages 2307-2316.
Crossref
Heon Yung Gee, Fujian Zhang, Shazia Ashraf, Stefan Kohl, Carolin E. Sadowski, Virginia Vega-Warner, Weibin Zhou, Svjetlana Lovric, Humphrey Fang, Margaret Nettleton, Jun-yi Zhu, Julia Hoefele, Lutz T. Weber, Ludmila Podracka, Andrej Boor, Henry Fehrenbach, Jeffrey W. Innis, Joseph Washburn, Shawn Levy, Richard P. Lifton, Edgar A. Otto, Zhe Han & Friedhelm Hildebrandt. (2015) KANK deficiency leads to podocyte dysfunction and nephrotic syndrome. Journal of Clinical Investigation 125:6, pages 2375-2384.
Crossref
Richard Robins, Cindy Baldwin, Lamine Aoudjit, Indra R. Gupta & Tomoko Takano. (2015) Loss of Rho-GDIα sensitizes podocytes to lipopolysaccharide-mediated injury. American Journal of Physiology-Renal Physiology 308:11, pages F1207-F1216.
Crossref
Yasuhiro TakiMasayuki OdaAnna SedukhinaAtsuko Ikemori, Naoki MatsumotoYugo ShibagakiToshio Kumai. (2015) Proteomic Analysis Reveals the Association between the Rho-GDI Signaling Pathway and Kidney Injury in Spontaneously Hypertensive and Hyperlipidemic Rats. Journal of St. Marianna University 6:2, pages 141-149.
Crossref
Wilhelm Kriz, Brunhilde Hähnel, Hiltraud Hosser, Sigrid Rösener & Rüdiger Waldherr. (2014) Structural Analysis of How Podocytes Detach from the Glomerular Basement Membrane Under Hypertrophic Stress. Frontiers in Endocrinology 5.
Crossref
Guofeng Gao, Weiwei Wang, Raghu K. Tadagavadi, Nicole E. Briley, Michael I. Love, Barbara A. Miller & W. Brian Reeves. (2014) TRPM2 mediates ischemic kidney injury and oxidant stress through RAC1. Journal of Clinical Investigation 124:11, pages 4989-5001.
Crossref
Rachel Lennon, Michael J. Randles & Martin J. Humphries. (2014) The Importance of Podocyte Adhesion for a Healthy Glomerulus. Frontiers in Endocrinology 5.
Crossref
Marianne DelvilleTara K. SigdelChangli WeiJing LiSzu-Chuan HsiehAlessia FornoniGeorge W. BurkePatrick BrunevalMaarten NaesensAnnette JacksonNada AlachkarGuillaume CanaudChristophe LegendreDany AnglicheauJochen ReiserMinnie M. Sarwal. (2014) A circulating antibody panel for pretransplant prediction of FSGS recurrence after kidney transplantation. Science Translational Medicine 6:256.
Crossref
Takanori Kumagai, Cindy Baldwin, Lamine Aoudjit, Lisa Nezvitsky, Richard Robins, Ruihua Jiang & Tomoko Takano. (2014) Protein Tyrosine Phosphatase 1B Inhibition Protects against Podocyte Injury and Proteinuria. The American Journal of Pathology 184:8, pages 2211-2224.
Crossref
Laura A. New, Claire E. Martin & Nina Jones. (2014) Advances in slit diaphragm signaling. Current Opinion in Nephrology and Hypertension 23:4, pages 420-430.
Crossref
Richard Robins & Tomoko Takano. (2014) Rho-GTPase Signalling in the Pathogenesis of Nephrotic Syndrome. Advances in Nephrology 2014, pages 1-11.
Crossref
Anna Mondini, Piergiorgio Messa & Maria Pia Rastaldi. (2014) The sclerosing glomerulus in mice and man. Current Opinion in Nephrology and Hypertension 23:3, pages 239-244.
Crossref
S. Akilesh. 2014. Pathobiology of Human Disease. Pathobiology of Human Disease 2734 2752 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.