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Article

Leucine-Rich Repeat Kinase 2 Binds to Neuronal Vesicles through Protein Interactions Mediated by Its C-Terminal WD40 Domain

Giovanni Piccolia Helmholtz Zentrum München, German Research Center for Environmental Health, Research Unit Protein Science, Neuherberg, Germany;b Institute of Neuroscience, National Research Council, Milan, Italy
,
Franco Onofric Department of Experimental Medicine, University of Genoa, Genoa, Italy
,
Maria Daniela Cirnarub Institute of Neuroscience, National Research Council, Milan, Italy
,
Christoph J. O. Kaiserd Center for Integrated Protein Science Munich and Technische Universität München, Department of Chemistry, Garching, Germany
,
Pravinkumar Jagtapd Center for Integrated Protein Science Munich and Technische Universität München, Department of Chemistry, Garching, Germany;e Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Structural Biology, Neuherberg, Germany
,
Andreas Kastenmüllerd Center for Integrated Protein Science Munich and Technische Universität München, Department of Chemistry, Garching, Germany
,
Francesca Pischeddab Institute of Neuroscience, National Research Council, Milan, Italy
,
Antonella Martec Department of Experimental Medicine, University of Genoa, Genoa, Italy
,
Felix von Zweydorff Eberhard Karls University Tübingen, Institute for Ophthalmic Research, Medical Proteome Center, Tübingen, Germany
,
Andreas Vogta Helmholtz Zentrum München, German Research Center for Environmental Health, Research Unit Protein Science, Neuherberg, Germany;f Eberhard Karls University Tübingen, Institute for Ophthalmic Research, Medical Proteome Center, Tübingen, Germany
,
Florian Giesertg Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Developmental Genetics, Neuherberg, Germany
,
Lifeng Panh Division of Life Science, Centre of Systems Biology and Human Health, Institute for Advanced Study and School of Science, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong
,
Flavia Antonuccii Department of Biotechnology and Translational Medicine, University of Milan and Humanitas Clinical and Research Center, Rozzano, Italy
,
Christina Kielj CRG-EMBL System Biology Program, Centre de Regulació Genòmica UPF, Barcelona, Spain
,
Mingjie Zhangh Division of Life Science, Centre of Systems Biology and Human Health, Institute for Advanced Study and School of Science, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong
,
Sevil Weinkaufd Center for Integrated Protein Science Munich and Technische Universität München, Department of Chemistry, Garching, Germany
,
Michael Sattlerd Center for Integrated Protein Science Munich and Technische Universität München, Department of Chemistry, Garching, Germany;e Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Structural Biology, Neuherberg, Germany
,
Carlo Salab Institute of Neuroscience, National Research Council, Milan, Italy
,
Michela Matteolii Department of Biotechnology and Translational Medicine, University of Milan and Humanitas Clinical and Research Center, Rozzano, Italy
,
Marius Ueffinga Helmholtz Zentrum München, German Research Center for Environmental Health, Research Unit Protein Science, Neuherberg, Germany;f Eberhard Karls University Tübingen, Institute for Ophthalmic Research, Medical Proteome Center, Tübingen, Germany
&
Christian Johannes Gloecknera Helmholtz Zentrum München, German Research Center for Environmental Health, Research Unit Protein Science, Neuherberg, Germany;f Eberhard Karls University Tübingen, Institute for Ophthalmic Research, Medical Proteome Center, Tübingen, GermanyCorrespondence[email protected]
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Pages 2147-2161 | Received 23 Jul 2013, Accepted 18 Mar 2014, Published online: 20 Mar 2023

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Daleum Nam, Hyejung Kim, Dong-Joo Choi, Yun-Hee Bae, Byoung Dae Lee, Ilhong Son & Wongi Seol. (2018) Characterization of Parkinson’s disease-related pathogenic TMEM230 mutants. Animal Cells and Systems 22:2, pages 140-147.
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Paul Galatsis. (2017) Leucine-rich repeat kinase 2 inhibitors: a patent review (2014-2016). Expert Opinion on Therapeutic Patents 27:6, pages 667-676.
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