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Article

The RasGAP Proteins Ira2 and Neurofibromin Are Negatively Regulated by Gpb1 in Yeast and ETEA in Humans

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Pages 2264-2279 | Received 15 Sep 2008, Accepted 09 Feb 2010, Published online: 20 Mar 2023

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Michelle de la Vega, James F. Burrows & James A. Johnston. (2011) Ubiquitination. Small GTPases 2:4, pages 192-201.
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Crossref
Tingting Geng, Duomeng Yang, Tao Lin, Jason G. Cahoon & Penghua Wang. (2022) UBXN3B Controls Immunopathogenesis of Arthritogenic Alphaviruses by Maintaining Hematopoietic Homeostasis. mBio 13:6.
Crossref
Sergio Lois, Juan Báez-Flores, María Isidoro-García, Jesus Lacal & Juan Carlos Triviño. (2022) Identification of Germinal Neurofibromin Hotspots. Biomedicines 10:8, pages 2044.
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Xuan Cai, Shikun Xiang, Wenhui He, Mengxi Tang, Shimei Zhang, Deng Chen, Xinrong Zhang, Caiyun Liu, Guotian Li, Junjie Xing, Yunfeng Li, Xiao‐Lin Chen & Yanfang Nie. (2022) Deubiquitinase Ubp3 regulates ribophagy and deubiquitinates Smo1 for appressorium‐mediated infection by Magnaporthe oryzae . Molecular Plant Pathology 23:6, pages 832-844.
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Shu-Chun Chang, Bo-Xiang Zhang & Jeak Ling Ding. (2022) E2-E3 ubiquitin enzyme pairing - partnership in provoking or mitigating cancers. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1877:2, pages 188679.
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Anaïs Carniciu, Alon Kahana & Leonard A. Levin. 2022. Albert and Jakobiec's Principles and Practice of Ophthalmology. Albert and Jakobiec's Principles and Practice of Ophthalmology 5217 5262 .
Pavel Ershov, Leonid Kaluzhskiy, Yuri Mezentsev, Evgeniy Yablokov, Oksana Gnedenko & Alexis Ivanov. (2021) Enzymes in the Cholesterol Synthesis Pathway: Interactomics in the Cancer Context. Biomedicines 9:8, pages 895.
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Patricia P Peterson & Zhengchang Liu. (2021) Identification and characterization of rapidly accumulating sch9Δ suppressor mutations in Saccharomyces cerevisiae . G3 Genes|Genomes|Genetics 11:7.
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Shuang Li, Yuanyuan Li, Blake R. Rushing, Sarah E. Harris, Susan L. McRitchie, Janice C. Jones, Daniel Dominguez, Susan J. Sumner & Henrik G. Dohlman. (2021) Multi-omics analysis of glucose-mediated signaling by a moonlighting Gβ protein Asc1/RACK1. PLOS Genetics 17:7, pages e1009640.
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José L. Neira, Sonia Vega, Sergio Martínez-Rodríguez & Adrián Velázquez-Campoy. (2021) The isolated GTPase-activating-protein-related domain of neurofibromin-1 has a low conformational stability in solution. Archives of Biochemistry and Biophysics 700, pages 108767.
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Mohammed Bergoug, Michel Doudeau, Fabienne Godin, Christine Mosrin, Béatrice Vallée & Hélène Bénédetti. (2020) Neurofibromin Structure, Functions and Regulation. Cells 9:11, pages 2365.
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Charoula Peta, Emmanouella Tsirimonaki, Dimitris Samouil, Kyriaki Georgiadou & Dimitra Mangoura. (2020) Nuclear Isoforms of Neurofibromin Are Required for Proper Spindle Organization and Chromosome Segregation. Cells 9:11, pages 2348.
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Mukul Sherekar, Sae-Won Han, Rodolfo Ghirlando, Simon Messing, Matthew Drew, Dana Rabara, Timothy Waybright, Puneet Juneja, Hugh O'Neill, Christopher B. Stanley, Debsindhu Bhowmik, Arvind Ramanathan, Sriram Subramaniam, Dwight V. Nissley, William Gillette, Frank McCormick & Dominic Esposito. (2020) Biochemical and structural analyses reveal that the tumor suppressor neurofibromin (NF1) forms a high-affinity dimer. Journal of Biological Chemistry 295:4, pages 1105-1119.
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Rachel M. Carnes, Robert A. Kesterson, Bruce R. Korf, James A. Mobley & Deeann Wallis. (2019) Affinity Purification of NF1 Protein–Protein Interactors Identifies Keratins and Neurofibromin Itself as Binding Partners. Genes 10:9, pages 650.
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Klaus Scheffzek & Giridhar Shivalingaiah. (2019) Ras-Specific GTPase-Activating Proteins—Structures, Mechanisms, and Interactions. Cold Spring Harbor Perspectives in Medicine 9:3, pages a031500.
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Priyanka Jain, Subhash Chandra Sethi, Vavilala A. Pratyusha, Pramita Garai, Nilofer Naqvi, Sonali Singh, Kalpana Pawar, Niti Puri & Sneha Sudha Komath. (2018) Ras signaling activates glycosylphosphatidylinositol (GPI) anchor biosynthesis via the GPI–N-acetylglucosaminyltransferase (GPI–GnT) in Candida albicans. Journal of Biological Chemistry 293:31, pages 12222-12238.
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Vavilala A. Pratyusha, Guiliana Soraya Victoria, Mohammad Firoz Khan, Dominic T. Haokip, Bhawna Yadav, Nibedita Pal, Subhash Chandra Sethi, Priyanka Jain, Sneh Lata Singh, Sobhan Sen & Sneha Sudha Komath. (2018) Ras hyperactivation versus overexpression: Lessons from Ras dynamics in Candida albicans. Scientific Reports 8:1.
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Revathi S. Iyer & Paike Jayadeva Bhat. (2017) KRH1 and KRH2 are functionally non-redundant in signaling for pseudohyphal differentiation in Saccharomyces cerevisiae. Current Genetics 63:5, pages 851-859.
Crossref
Khosrow Rezvani. (2016) UBXD Proteins: A Family of Proteins with Diverse Functions in Cancer. International Journal of Molecular Sciences 17:10, pages 1724.
Crossref
Matthew B. Taylor, Joann Phan, Jonathan T. Lee, Madelyn McCadden & Ian M. Ehrenreich. (2016) Diverse genetic architectures lead to the same cryptic phenotype in a yeast cross. Nature Communications 7:1.
Crossref
. 2016. Neurocutaneous Disorders. Neurocutaneous Disorders 3 104 .
Ammara Abdullah, Sanam Sane, Kate A. Branick, Jessica L. Freeling, Hongmin Wang, Dong Zhang & Khosrow Rezvani. (2015) A plant alkaloid, veratridine, potentiates cancer chemosensitivity by UBXN2A-dependent inhibition of an oncoprotein, mortalin-2. Oncotarget 6:27, pages 23561-23581.
Crossref
Ken Harata & Yasuyuki Kubo. (2014) Ras GTPase Activating Protein CoIra1 Is Involved in Infection-Related Morphogenesis by Regulating cAMP and MAPK Signaling Pathways through CoRas2 in Colletotrichum orbiculare. PLoS ONE 9:10, pages e109045.
Crossref
F. Galello, S. Moreno & S. Rossi. (2014) Interacting proteins of protein kinase A regulatory subunit in Saccharomyces cerevisiae. Journal of Proteomics 109, pages 261-275.
Crossref
Kate Sullivan, Jad El-Hoss, Kate G.R. Quinlan, Nikita Deo, Fleur Garton, Jane T.C. Seto, Marie Gdalevitch, Nigel Turner, Gregory J. Cooney, Mateusz Kolanczyk, Kathryn N. North, David G. Little & Aaron Schindeler. (2014) NF1 is a critical regulator of muscle development and metabolism. Human Molecular Genetics 23:5, pages 1250-1259.
Crossref
Ken Peeters & Johan M. Thevelein. 2014. Molecular Mechanisms in Yeast Carbon Metabolism. Molecular Mechanisms in Yeast Carbon Metabolism 21 56 .
Renata Tisi, Fiorella Belotti & Enzo Martegani. 2014. Ras Signaling. Ras Signaling 359 390 .
Brandon D. Gaytán, Alex V. Loguinov, Stephen R. Lantz, Jan-Michael Lerot, Nancy D. Denslow & Chris D. Vulpe. (2013) Functional Profiling Discovers the Dieldrin Organochlorinated Pesticide Affects Leucine Availability in Yeast. Toxicological Sciences 132:2, pages 347-358.
Crossref
Yang Li & Yuqi Wang. (2013) Ras Protein/cAMP-dependent Protein Kinase Signaling Is Negatively Regulated by a Deubiquitinating Enzyme, Ubp3, in Yeast. Journal of Biological Chemistry 288:16, pages 11358-11365.
Crossref
James A. Olzmann, Caleb M. Richter & Ron R. Kopito. (2013) Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover. Proceedings of the National Academy of Sciences 110:4, pages 1345-1350.
Crossref
Jin Ye. (2012) Cellular responses to unsaturated fatty acids mediated by their sensor Ubxd8. Frontiers in Biology 7:5, pages 397-403.
Crossref
Zhiwei Wang, Hiroyuki Inuzuka, Jiateng Zhong, Lixin Wan, Hidefumi Fukushima, Fazlul H. Sarkar & Wenyi Wei. (2012) Tumor suppressor functions of FBW7 in cancer development and progression. FEBS Letters 586:10, pages 1409-1418.
Crossref
Claudio De Virgilio. (2012) The essence of yeast quiescence. FEMS Microbiology Reviews 36:2, pages 306-339.
Crossref
Michitaka Suzuki, Toshihiko Otsuka, Yuki Ohsaki, Jinglei Cheng, Takako Taniguchi, Hisashi Hashimoto, Hisaaki Taniguchi & Toyoshi Fujimoto. (2012) Derlin-1 and UBXD8 are engaged in dislocation and degradation of lipidated ApoB-100 at lipid droplets. Molecular Biology of the Cell 23:5, pages 800-810.
Crossref
Paul J Cullen & George F SpragueJr.Jr.. (2012) The Regulation of Filamentous Growth in Yeast. Genetics 190:1, pages 23-49.
Crossref
Stefan Brückner & Hans-Ulrich Mösch. (2012) Choosing the right lifestyle: adhesion and development in Saccharomyces cerevisiae . FEMS Microbiology Reviews 36:1, pages 25-58.
Crossref
Klaus Scheffzek & Stefan Welti. 2012. Neurofibromatosis Type 1. Neurofibromatosis Type 1 305 326 .
Conrad C. Weihl. (2011) Another VCP interactor: NF is enough. Journal of Clinical Investigation 121:12, pages 4627-4630.
Crossref
Mingjia Tan, Yongchao Zhao, Sun-Jung Kim, Margaret Liu, Lijun Jia, Thomas L. Saunders, Yuan Zhu & Yi Sun. (2011) SAG/RBX2/ROC2 E3 Ubiquitin Ligase Is Essential for Vascular and Neural Development by Targeting NF1 for Degradation. Developmental Cell 21:6, pages 1062-1076.
Crossref
Stefan Welti, Sonja Kühn, Igor D'Angelo, Britta Brügger, Dieter Kaufmann & Klaus Scheffzek. (2011) Structural and biochemical consequences of NF1 associated nontruncating mutations in the Sec14-PH module of neurofibromin. Human Mutation 32:2, pages 191-197.
Crossref
Roli Budhwar, Ailan Lu & Jeanne P. Hirsch. (2010) Nutrient Control of Yeast PKA Activity Involves Opposing Effects on Phosphorylation of the Bcy1 Regulatory Subunit. Molecular Biology of the Cell 21:21, pages 3749-3758.
Crossref
. (2010) Current awareness on yeast. Yeast 27:10, pages 867-874.
Crossref
Minao FURUMURA & Juichiro NAKAYAMA. (2010) . Nishi Nihon Hifuka 72:5, pages 500-506.
Crossref

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