Advanced search
Publication Cover
Molecular and Cellular Biology Volume 29, 2009 - Issue 5
Submit an article Journal homepage
9
Views
15
CrossRef citations to date
0
Altmetric
Article

The C-Terminal Domain of Cernunnos/XLF Is Dispensable for DNA Repair In Vivo

Laurent Malivert1 INSERM, Hôpital Necker-Enfants Malades, U768, Unité de Développement Normal et Pathologique du Système Immunitaire;2 Université Paris Diderot—Paris 7, Bâtiment les Grands Moulins, 16 rue Marguerite Duras, 75205 Paris Cedex 13
,
Isabelle Callebaut3 Département de Biologie Structurale, IMPMC, CNRS UMR7590, Universités Paris 6 et 7
,
Paola Rivera-Munoz1 INSERM, Hôpital Necker-Enfants Malades, U768, Unité de Développement Normal et Pathologique du Système Immunitaire;2 Université Paris Diderot—Paris 7, Bâtiment les Grands Moulins, 16 rue Marguerite Duras, 75205 Paris Cedex 13
,
Alain Fischer1 INSERM, Hôpital Necker-Enfants Malades, U768, Unité de Développement Normal et Pathologique du Système Immunitaire;4 Université Paris-Descartes, Faculté de Médecine René Descartes, F-75005Paris, France;5 Assistance Publique-Hôpitaux de Paris, Hôpital Necker-Enfants Malades, Unité d'Immunologie et d'Hématologie, F-75015 Paris
,
Jean-Paul Mornon3 Département de Biologie Structurale, IMPMC, CNRS UMR7590, Universités Paris 6 et 7
,
Patrick Revy1 INSERM, Hôpital Necker-Enfants Malades, U768, Unité de Développement Normal et Pathologique du Système Immunitaire;4 Université Paris-Descartes, Faculté de Médecine René Descartes, F-75005Paris, France
&
Jean-Pierre de Villartay1 INSERM, Hôpital Necker-Enfants Malades, U768, Unité de Développement Normal et Pathologique du Système Immunitaire;4 Université Paris-Descartes, Faculté de Médecine René Descartes, F-75005Paris, France;5 Assistance Publique-Hôpitaux de Paris, Hôpital Necker-Enfants Malades, Unité d'Immunologie et d'Hématologie, F-75015 ParisCorrespondence[email protected]
 show all
Pages 1116-1122 | Received 30 Sep 2008, Accepted 09 Dec 2008, Published online: 21 Mar 2023

Citations (15)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Sunetra Roy, Abinadabe J. de Melo, Yao Xu, Satish K. Tadi, Aurélie Négrel, Eric Hendrickson, Mauro Modesti & Katheryn Meek. (2015) XRCC4/XLF Interaction Is Variably Required for DNA Repair and Is Not Required for Ligase IV Stimulation. Molecular and Cellular Biology 35:17, pages 3017-3028.
Read now

Articles from other publishers (14)

Sean M Carney, Andrew T Moreno, Sadie C Piatt, Metztli Cisneros-Aguirre, Felicia Wednesday Lopezcolorado, Jeremy M Stark & Joseph J Loparo. (2020) XLF acts as a flexible connector during non-homologous end joining. eLife 9.
Crossref
Yanira Gonzalez-Rodriguez & Samuel F. Bunting. (2019) XLF extends its range from DNA repair to replication. Journal of Cell Biology 218:7, pages 2075-2076.
Crossref
Clement Nemoz, Virginie Ropars, Philippe Frit, Amandine Gontier, Pascal Drevet, Jinchao Yu, Raphaël Guerois, Aurelien Pitois, Audrey Comte, Christine Delteil, Nadia Barboule, Pierre Legrand, Sonia Baconnais, Yandong Yin, Satish Tadi, Emeline Barbet-Massin, Imre Berger, Eric Le Cam, Mauro Modesti, Eli Rothenberg, Patrick Calsou & Jean Baptiste Charbonnier. (2018) XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining. Nature Structural & Molecular Biology 25:10, pages 971-980.
Crossref
Vijay Menon & Lawrence F. Povirk. (2017) XLF/Cernunnos: An important but puzzling participant in the nonhomologous end joining DNA repair pathway. DNA Repair 58, pages 29-37.
Crossref
Stuart L. Rulten & Gabrielle J. Grundy. (2017) Non-homologous end joining: Common interaction sites and exchange of multiple factors in the DNA repair process. BioEssays 39:3, pages 1600209.
Crossref
Manabu KOIKE, Yasutomo YUTOKU & Aki KOIKE. (2015) Dynamic changes in subcellular localization of cattle XLF during cell cycle, and focus formation of cattle XLF at DNA damage sites immediately after irradiation. Journal of Veterinary Medical Science 77:9, pages 1109-1114.
Crossref
Dailia B. Francis, Mikhail Kozlov, Jose Chavez, Jennifer Chu, Shruti Malu, Mary Hanna & Patricia Cortes. (2014) DNA Ligase IV regulates XRCC4 nuclear localization. DNA Repair 21, pages 36-42.
Crossref
Brandi L. Mahaney, Susan P. Lees-Miller & Jennifer A. Cobb. (2014) The C-terminus of Nej1 is critical for nuclear localization and non-homologous end-joining. DNA Repair 14, pages 9-16.
Crossref
Anna Villa, Despina Moshous, Jean-Pierre de Villartay, Luigi D. Notarangelo & Fabio Candotti. 2014. Stiehm's Immune Deficiencies. Stiehm's Immune Deficiencies 87 141 .
Brandi L. MahaneyMichal HammelKatheryn MeekJohn A. TainerSusan P. Lees-Miller. (2013) XRCC4 and XLF form long helical protein filaments suitable for DNA end protection and alignment to facilitate DNA double strand break repair. Biochemistry and Cell Biology 91:1, pages 31-41.
Crossref
Qian WuTakashi OchiDijana Matak-VinkovicCarol V. RobinsonDimitri Y. ChirgadzeTom L. Blundell. (2011) Non-homologous end-joining partners in a helical dance: structural studies of XLF–XRCC4 interactions. Biochemical Society Transactions 39:5, pages 1387-1392.
Crossref
Michal Hammel, Martial Rey, Yaping Yu, Rajam S. Mani, Scott Classen, Mona Liu, Michael E. Pique, Shujuan Fang, Brandi L. Mahaney, Michael Weinfeld, David C. Schriemer, Susan P. Lees-Miller & John A. Tainer. (2011) XRCC4 Protein Interactions with XRCC4-like Factor (XLF) Create an Extended Grooved Scaffold for DNA Ligation and Double Strand Break Repair. Journal of Biological Chemistry 286:37, pages 32638-32650.
Crossref
Ken-ichi Yano, Keiko Morotomi-Yano, Kyung-Jong Lee & David J. Chen. (2011) Functional significance of the interaction with Ku in DNA double-strand break recognition of XLF. FEBS Letters 585:6, pages 841-846.
Crossref
Laurent Malivert, Virginie Ropars, Marcela Nunez, Pascal Drevet, Simona Miron, Guilhem Faure, Raphael Guerois, Jean-Paul Mornon, Patrick Revy, Jean-Baptiste Charbonnier, Isabelle Callebaut & Jean-Pierre de Villartay. (2010) Delineation of the Xrcc4-interacting Region in the Globular Head Domain of Cernunnos/XLF. Journal of Biological Chemistry 285:34, pages 26475-26483.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.