Molecular and Cellular Biology, Volume 29, Issue 5 (2009)

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Molecular and Cellular Biology, Volume 29, Issue 5 (2009)

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Articles

Article
Regulation of SMN Protein Stability
Barrington G. Burnett, Eric Muñoz, Animesh Tandon, Deborah Y. Kwon, Charlotte J. Sumner & Kenneth H. Fischbeck
Pages: 1107-1115
Published online: 21 Mar 2023
AbstractforRegulation of SMN Protein Stability | Full Text | References | PDF (792.2 KB) | Supplemental
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Article
The C-Terminal Domain of Cernunnos/XLF Is Dispensable for DNA Repair In Vivo
Laurent Malivert, Isabelle Callebaut, Paola Rivera-Munoz, Alain Fischer, Jean-Paul Mornon, Patrick Revy & Jean-Pierre de Villartay
Pages: 1116-1122
Published online: 21 Mar 2023
AbstractforThe C-Terminal Domain of Cernunnos/XLF Is Dispensable for DNA Repair In Vivo | Full Text | References | PDF (884.7 KB) | Supplemental
  • 9 Views
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Article
Postrecruitment Regulation of RNA Polymerase II Directs Rapid Signaling Responses at the Promoters of Estrogen Target Genes
Miltiadis Kininis, Gary D. Isaacs, Leighton J. Core, Nasun Hah & W. Lee Kraus
Pages: 1123-1133
Published online: 21 Mar 2023
AbstractforPostrecruitment Regulation of RNA Polymerase II Directs Rapid Signaling Responses at the Promoters of Estrogen Target Genes | Full Text | References | PDF (4.1 MB) | Supplemental
  • 49 Views
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Article
The Ku80 Carboxy Terminus Stimulates Joining and Artemis-Mediated Processing of DNA Ends
Eric Weterings, Nicole S. Verkaik, Guido Keijzers, Bogdan I. Florea, Shih-Ya Wang, Laura G. Ortega, Naoya Uematsu, David J. Chen & Dik C. van Gent
Pages: 1134-1142
Published online: 21 Mar 2023
AbstractforThe Ku80 Carboxy Terminus Stimulates Joining and Artemis-Mediated Processing of DNA Ends | Full Text | References | PDF (1.2 MB)
  • 26 Views
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Article
Prep1 Directly Regulates the Intrinsic Apoptotic Pathway by Controlling Bcl-XL Levels
Nicola Micali, Carmelo Ferrai, Luis C. Fernandez-Diaz, Francesco Blasi & Massimo P. Crippa
Pages: 1143-1151
Published online: 21 Mar 2023
AbstractforPrep1 Directly Regulates the Intrinsic Apoptotic Pathway by Controlling Bcl-XL Levels | Full Text | References | PDF (1.2 MB) | Supplemental
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Article
Stability of Eukaryotic Translation Initiation Factor 4E mRNA Is Regulated by HuR, and This Activity Is Dysregulated in Cancer
Ivan Topisirovic, Nadeem Siddiqui, Slobodanka Orolicki, Lucy A. Skrabanek, Mathieu Tremblay, Trang Hoang & Katherine L. B. Borden
Pages: 1152-1162
Published online: 21 Mar 2023
AbstractforStability of Eukaryotic Translation Initiation Factor 4E mRNA Is Regulated by HuR, and This Activity Is Dysregulated in Cancer | Full Text | References | PDF (2.7 MB) | Supplemental
  • 48 Views
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Article
Differential Contribution of the Gata1 Gene Hematopoietic Enhancer to Erythroid Differentiation
Mikiko Suzuki, Takashi Moriguchi, Kinuko Ohneda & Masayuki Yamamoto
Pages: 1163-1175
Published online: 21 Mar 2023
AbstractforDifferential Contribution of the Gata1 Gene Hematopoietic Enhancer to Erythroid Differentiation | Full Text | References | PDF (2.4 MB) | Supplemental
  • 59 Views
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Article
The Double-Histone-Acetyltransferase Complex ATAC Is Essential for Mammalian Development
Sebastián Guelman, Kenji Kozuka, Yifan Mao, Victoria Pham, Mark J. Solloway, John Wang, Jiansheng Wu, Jennie R. Lill & Jiping Zha
Pages: 1176-1188
Published online: 21 Mar 2023
AbstractforThe Double-Histone-Acetyltransferase Complex ATAC Is Essential for Mammalian Development | Full Text | References | PDF (4.2 MB)
  • 147 Views
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Article
Plk3 Interacts with and Specifically Phosphorylates VRK1 in Ser342, a Downstream Target in a Pathway That Induces Golgi Fragmentation
Inmaculada López-Sánchez, Marta Sanz-García & Pedro A. Lazo
Pages: 1189-1201
Published online: 21 Mar 2023
AbstractforPlk3 Interacts with and Specifically Phosphorylates VRK1 in Ser342, a Downstream Target in a Pathway That Induces Golgi Fragmentation | Full Text | References | PDF (6.1 MB) | Supplemental
  • 37 Views
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Article
Trypanosoma brucei Spliced Leader RNA Maturation by the Cap 1 2′-O-Ribose Methyltransferase and SLA1 H/ACA snoRNA Pseudouridine Synthase Complex
Jesse R. Zamudio, Bidyottam Mittra, Arnab Chattopadhyay, James A. Wohlschlegel, Nancy R. Sturm & David A. Campbell
Pages: 1202-1211
Published online: 21 Mar 2023
AbstractforTrypanosoma brucei Spliced Leader RNA Maturation by the Cap 1 2′-O-Ribose Methyltransferase and SLA1 H/ACA snoRNA Pseudouridine Synthase Complex | Full Text | References | PDF (736.9 KB) | Supplemental
  • 38 Views
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Article
The Transition of Closely Opposed Lesions to Double-Strand Breaks during Long-Patch Base Excision Repair Is Prevented by the Coordinated Action of DNA Polymerase δ and Rad27/Fen1
Wenjian Ma, Vijayalakshmi Panduri, Joan F. Sterling, Bennett Van Houten, Dmitry A. Gordenin & Michael A. Resnick
Pages: 1212-1221
Published online: 21 Mar 2023
AbstractforThe Transition of Closely Opposed Lesions to Double-Strand Breaks during Long-Patch Base Excision Repair Is Prevented by the Coordinated Action of DNA Polymerase δ and Rad27/Fen1 | Full Text | References | PDF (1 MB) | Supplemental
  • 23 Views
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Article
PTEN Loss Promotes Mitochondrially Dependent Type II Fas-Induced Apoptosis via PEA-15
James W. Peacock, Jodie Palmer, Dieter Fink, Stephen Ip, Eric M. Pietras, Alice L.-F. Mui, Stephen W. Chung, Martin E. Gleave, Michael E. Cox, Ramon Parsons, Marcus E. Peter & Christopher J. Ong
Pages: 1222-1234
Published online: 21 Mar 2023
AbstractforPTEN Loss Promotes Mitochondrially Dependent Type II Fas-Induced Apoptosis via PEA-15 | Full Text | References | PDF (1.1 MB)
  • 17 Views
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Article
Unscheduled Akt-Triggered Activation of Cyclin-Dependent Kinase 2 as a Key Effector Mechanism of Apoptin's Anticancer Toxicity
Subbareddy Maddika, Soumya Panigrahi, Emilia Wiechec, Sebastian Wesselborg, Ute Fischer, Klaus Schulze-Osthoff & Marek Los
Pages: 1235-1248
Published online: 21 Mar 2023
AbstractforUnscheduled Akt-Triggered Activation of Cyclin-Dependent Kinase 2 as a Key Effector Mechanism of Apoptin's Anticancer Toxicity | Full Text | References | PDF (2.9 MB)
  • 24 Views
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Article
Activation of Stat3 by Heregulin/ErbB-2 through the Co-Option of Progesterone Receptor Signaling Drives Breast Cancer Growth
Cecilia J. Proietti, Cinthia Rosemblit, Wendy Beguelin, Martín A. Rivas, María Celeste Díaz Flaqué, Eduardo H. Charreau, Roxana Schillaci & Patricia V. Elizalde
Pages: 1249-1265
Published online: 21 Mar 2023
AbstractforActivation of Stat3 by Heregulin/ErbB-2 through the Co-Option of Progesterone Receptor Signaling Drives Breast Cancer Growth | Full Text | References | PDF (2 MB) | Supplemental
  • 11 Views
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Article
A Role for DNA Polymerase μ in the Emerging DJH Rearrangements of the Postgastrulation Mouse Embryo
Beatriz Gozalbo-López, Paula Andrade, Gloria Terrados, Belén de Andrés, Natalia Serrano, Isabel Cortegano, Beatriz Palacios, Antonio Bernad, Luis Blanco, Miguel A. R. Marcos & María Luisa Gaspar
Pages: 1266-1275
Published online: 21 Mar 2023
AbstractforA Role for DNA Polymerase μ in the Emerging DJH Rearrangements of the Postgastrulation Mouse Embryo | Full Text | References | PDF (967.7 KB) | Supplemental
  • 14 Views
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Article
An Xpb Mouse Model for Combined Xeroderma Pigmentosum and Cockayne Syndrome Reveals Progeroid Features upon Further Attenuation of DNA Repair
Jaan-Olle Andressoo, Geert Weeda, Jan de Wit, James R. Mitchell, Rudolf B. Beems, Harry van Steeg, Gijsbertus T. J. van der Horst & Jan H. Hoeijmakers
Pages: 1276-1290
Published online: 21 Mar 2023
AbstractforAn Xpb Mouse Model for Combined Xeroderma Pigmentosum and Cockayne Syndrome Reveals Progeroid Features upon Further Attenuation of DNA Repair | Full Text | References | PDF (1.5 MB)
  • 21 Views
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Article
Inhibition of Microtubule Assembly in Osteoblasts Stimulates Bone Morphogenetic Protein 2 Expression and Bone Formation through Transcription Factor Gli2
Ming Zhao, Seon-Yle Ko, Jin-Hua Liu, Di Chen, Jianghong Zhang, Baolin Wang, Stephen E. Harris, Babatunde O. Oyajobi & Gregory R. Mundy
Pages: 1291-1305
Published online: 21 Mar 2023
AbstractforInhibition of Microtubule Assembly in Osteoblasts Stimulates Bone Morphogenetic Protein 2 Expression and Bone Formation through Transcription Factor Gli2 | Full Text | References | PDF (4.9 MB)
  • 13 Views
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Article
Raf Kinase Inhibitory Protein Function Is Regulated via a Flexible Pocket and Novel Phosphorylation-Dependent Mechanism
Alexey E. Granovsky, Matthew C. Clark, Dan McElheny, Gary Heil, Jia Hong, Xuedong Liu, Youngchang Kim, Grazyna Joachimiak, Andrzej Joachimiak, Shohei Koide & Marsha Rich Rosner
Pages: 1306-1320
Published online: 21 Mar 2023
AbstractforRaf Kinase Inhibitory Protein Function Is Regulated via a Flexible Pocket and Novel Phosphorylation-Dependent Mechanism | Full Text | References | PDF (4.9 MB) | Supplemental
  • 27 Views
  • 39 CrossRef citations
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Article
Acetylation-Dependent Interaction of SATB1 and CtBP1 Mediates Transcriptional Repression by SATB1
Prabhat Kumar Purbey, Sunita Singh, Dimple Notani, P. Pavan Kumar, Amita S. Limaye & Sanjeev Galande
Pages: 1321-1337
Published online: 21 Mar 2023
AbstractforAcetylation-Dependent Interaction of SATB1 and CtBP1 Mediates Transcriptional Repression by SATB1 | Full Text | References | PDF (2.2 MB) | Supplemental
  • 56 Views
  • 47 CrossRef citations
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Article
Ras Subcellular Localization Defines Extracellular Signal-Regulated Kinase 1 and 2 Substrate Specificity through Distinct Utilization of Scaffold Proteins
Berta Casar, Imanol Arozarena, Victoria Sanz-Moreno, Adán Pinto, Lorena Agudo-Ibáñez, Richard Marais, Robert E. Lewis, María T. Berciano & Piero Crespo
Pages: 1338-1353
Published online: 21 Mar 2023
AbstractforRas Subcellular Localization Defines Extracellular Signal-Regulated Kinase 1 and 2 Substrate Specificity through Distinct Utilization of Scaffold Proteins | Full Text | References | PDF (4.2 MB)
  • 57 Views
  • 86 CrossRef citations
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Article
Defective DNA Ligation during Short-Patch Single-Strand Break Repair in Ataxia Oculomotor Apraxia 1
John J. Reynolds, Sherif F. El-Khamisy, Sachin Katyal, Paula Clements, Peter J. McKinnon & Keith W. Caldecott
Pages: 1354-1362
Published online: 21 Mar 2023
AbstractforDefective DNA Ligation during Short-Patch Single-Strand Break Repair in Ataxia Oculomotor Apraxia 1 | Full Text | References | PDF (742 KB)
  • 33 Views
  • 50 CrossRef citations
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Article
SIRT1 Exerts Anti-Inflammatory Effects and Improves Insulin Sensitivity in Adipocytes
Takeshi Yoshizaki, Jill C. Milne, Takeshi Imamura, Simon Schenk, Noriyuki Sonoda, Jennie L. Babendure, Juu-Chin Lu, Jesse J. Smith, Michael R. Jirousek & Jerrold M. Olefsky
Pages: 1363-1374
Published online: 21 Mar 2023
AbstractforSIRT1 Exerts Anti-Inflammatory Effects and Improves Insulin Sensitivity in Adipocytes | Full Text | References | PDF (1.1 MB) | Supplemental
  • 120 Views
  • 321 CrossRef citations
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Article
Brd4 Coactivates Transcriptional Activation of NF-κB via Specific Binding to Acetylated RelA
Bo Huang, Xiao-Dong Yang, Ming-Ming Zhou, Keiko Ozato & Lin-Feng Chen
Pages: 1375-1387
Published online: 21 Mar 2023
AbstractforBrd4 Coactivates Transcriptional Activation of NF-κB via Specific Binding to Acetylated RelA | Full Text | References | PDF (771.8 KB)
  • 254 Views
  • 428 CrossRef citations
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