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Byung-Kwon Choi, Kenichiro Fujiwara, Tajhal Dayaram, Yolanda Darlington, Joshua Dickerson, Margaret A. Goodell & Lawrence A. Donehower. (2020) WIP1 dephosphorylation of p27Kip1 Serine 140 destabilizes p27Kip1 and reverses anti-proliferative effects of ATM phosphorylation. Cell Cycle 19:4, pages 479-491.
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Savitha S. Sharma & W. Jackson Pledger. (2016) The non-canonical functions of p27Kip1 in normal and tumor biology. Cell Cycle 15:9, pages 1189-1201.
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C. Elizabeth Caldon, C. Marcelo Sergio, Andrew Burgess, Andrew J. Deans, Robert L. Sutherland & Elizabeth A. Musgrove. (2013) Cyclin E2 induces genomic instability by mechanisms distinct from cyclin E1. Cell Cycle 12:4, pages 606-617.
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Leopoldo Iannuzzi, Angela Perucatti, Viviana Genualdo, Domenico Incarnato, Vincenzo Peretti, Roberto Rasero, Carlo Nebbia & Giulia Pia Di Meo. (2009) Chromosome analyses in dairy cows exposed to dioxins and dioxin-like PCBs using the SCE test. Italian Journal of Animal Science 8:sup2, pages 93-95.
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Articles from other publishers (44)
Ying Zhou, Rishun Fu, Mei Yang, Weihuang Liu & Zan Tong. (2023) Lycopene suppresses gastric cancer cell growth without affecting normal gastric epithelial cells. The Journal of Nutritional Biochemistry 116, pages 109313.
Crossref
Crossref
Jun Xiao, Siyan Jin, Xue Wang, Ju Huang & He Zou. (2022) CELF1 Selectively Regulates Alternative Splicing of DNA Repair Genes Associated With Cataract in Human Lens Cell Line. Biochemical Genetics.
Crossref
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Kanchisa Nakasen, Pranee Sriraj, Jatuporn Prathumtet, Thidarut Boonmars & Ratchadawan Aukkanimart. (2022) Trikatu, a Thai Ayurvedic Remedy of Piper nigrum, Piper retrofractum, and Zingiber officinale Promotes Anti-cholangiocarcinoma Cell Proliferation via Cell Cycle Arrest. Revista Brasileira de Farmacognosia 33:1, pages 222-229.
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Debora Bencivenga, Emanuela Stampone, Domenico Roberti, Fulvio Della Ragione & Adriana Borriello. (2021) p27Kip1, an Intrinsically Unstructured Protein with Scaffold Properties. Cells 10:9, pages 2254.
Crossref
Crossref
Asmita Pal, Soumee Sengupta & Rita Kundu. (2021) Tiliacora racemosa leaves induce oxidative stress mediated DNA damage leading to G2/M phase arrest and apoptosis in cervical cancer cells SiHa. Journal of Ethnopharmacology 269, pages 113686.
Crossref
Crossref
Davide Viotto, Francesca Russo, Ilaria Anania, Ilenia Segatto, Gian Luca Rampioni Vinciguerra, Alessandra Dall'Acqua, Riccardo Bomben, Tiziana Perin, Martina Cusan, Monica Schiappacassi, Lorenzo Gerratana, Sara D'Andrea, Francesca Citron, Filippo Vit, Lorena Musco, Maria Chiara Mattevi, Giorgia Mungo, Milena S Nicoloso, Maura Sonego, Samuele Massarut, Roberto Sorio, Luigi Barzan, Giovanni Franchin, Giorgio Giorda, Emilio Lucia, Sandro Sulfaro, Vittorio Giacomarra, Jerry Polesel, Federica Toffolutti, Vincenzo Canzonieri, Fabio Puglisi, Valter Gattei, Andrea Vecchione, Barbara Belletti & Gustavo Baldassarre. (2020)
CDKN1B
mutation and copy number variation are associated with tumor aggressiveness in luminal breast cancer
. The Journal of Pathology 253:2, pages 234-245.
Crossref
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Ako Yokoi, Toshihide Matsumoto, Yasuko Oguri, Yoshinori Hasegawa, Masataka Tochimoto, Mayu Nakagawa & Makoto Saegusa. (2020) Upregulation of fibronectin following loss of p53 function is a poor prognostic factor in ovarian carcinoma with a unique immunophenotype. Cell Communication and Signaling 18:1.
Crossref
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Eun-Jin An, Yumi Kim, Seung-Hyeon Lee, Hyun Min Ko, Won-Seok Chung & Hyeung-Jin Jang. (2020) Anti-Cancer Potential of Oxialis obtriangulata in Pancreatic Cancer Cell through Regulation of the ERK/Src/STAT3-Mediated Pathway. Molecules 25:10, pages 2301.
Crossref
Crossref
Han-Tsang Wu, Yi-En Liu, Kai-Wen Hsu, Yu-Fen Wang, Ya-Chi Chan, Yeh Chen & Dar-Ren Chen. (2020) MLL3 Induced by Luteolin Causes Apoptosis in Tamoxifen-Resistant Breast Cancer Cells through H3K4 Monomethylation and Suppression of the PI3K/AKT/mTOR Pathway. The American Journal of Chinese Medicine 48:05, pages 1221-1241.
Crossref
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Yutaka Hashimoto, Marisa Shiina, Pritha Dasgupta, Priyanka Kulkarni, Taku Kato, Ryan K. Wong, Yuichiro Tanaka, Varahram Shahryari, Shigekatsu Maekawa, Soichiro Yamamura, Sharanjot Saini, Guoren Deng, Z. Laura Tabatabai, Shahana Majid & Rajvir Dahiya. (2019) Upregulation of miR-130b Contributes to Risk of Poor Prognosis and Racial Disparity in African-American Prostate Cancer. Cancer Prevention Research 12:9, pages 585-598.
Crossref
Crossref
Zhiyan Zhan, Lili Song, Weiwei Zhang, Haihui Gu, Haizi Cheng, Yingwen Zhang, Yi Yang, Guangzhen Ji, Haizhong Feng, Tao Cheng & Yanxin Li. (2019) Absence of cyclin-dependent kinase inhibitor p27 or p18 increases efficiency of iPSC generation without induction of iPSC genomic instability. Cell Death & Disease 10:4.
Crossref
Crossref
Renaud T. Perchey, Murielle P. Serres, Ada Nowosad, Justine Creff, Caroline Callot, Alexandre Gay, Stéphane Manenti, Robert L. Margolis, Anastassia Hatzoglou & Arnaud Besson. (2018) p27Kip1 regulates the microtubule bundling activity of PRC1. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1865:11, pages 1630-1639.
Crossref
Crossref
Makoto Nakamura, Lizi Wu, James D. Griffin, Satoru Kojika, Kumiko Goi, Takeshi Inukai & Kanji Sugita. (2018) Notch1 activation enhances proliferation via activation of cdc2 and delays differentiation of myeloid progenitors. Leukemia Research 72, pages 34-44.
Crossref
Crossref
Yohei SaitoYoshikazu KuwaharaYumi YamamotoMasatoshi SuzukiManabu FukumotoFumihiko Yamamoto. (2018) ddY Mice Fed 10% Fat Diet Exhibit High p27KIP Expression and Delayed Hepatocyte DNA Synthesis During Liver Regeneration. Metabolic Syndrome and Related Disorders 16:6, pages 305-313.
Crossref
Crossref
Guangzhao Guan, Mahmoud M. Bakr, Norman Firth & Robert M. Love. (2018) Expression of cyclin D1 correlates with p27KIP1 and regulates the degree of oral dysplasia and squamous cell carcinoma differentiation. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 126:2, pages 174-183.
Crossref
Crossref
H Liu, H Qiu, Y Song, Y Liu, H Wang, M Lu, M Deng, Y Gu, J Yin, K Luo, Z Zhang, X Jia, G Zheng & Z He. (2016) Cip2a promotes cell cycle progression in triple-negative breast cancer cells by regulating the expression and nuclear export of p27Kip1. Oncogene 36:14, pages 1952-1964.
Crossref
Crossref
Stefania Berton, Martina Cusan, Ilenia Segatto, Francesca Citron, Sara D’Andrea, Sara Benevol, Michele Avanzo, Alessandra Dall’Acqua, Monica Schiappacassi, Robert G. Bristow, Barbara Belletti & Gustavo Baldassarre. (2017) Loss of p27kip1 increases genomic instability and induces radio-resistance in luminal breast cancer cells. Scientific Reports 7:1.
Crossref
Crossref
Shinichiro Kawamoto, Katsuya Yamamoto, Masanori Toyoda, Kimikazu Yakushijin, Hiroshi Matsuoka & Hironobu Minami. (2016) Constitutional t(8;22)(q24;q11.2) that mimics the variant Burkitt-type translocation in Philadelphia chromosome-positive chronic myeloid leukemia. International Journal of Hematology 105:2, pages 226-229.
Crossref
Crossref
Chinthalapally V. Rao, Adam S. Asch & Hiroshi Y. Yamada. (2017) Frequently mutated genes/pathways and genomic instability as prevention targets in liver cancer. Carcinogenesis 38:1, pages 2-11.
Crossref
Crossref
Sayaka Sobue, Naoki Mizutani, Yuka Aoyama, Yoshiyuki Kawamoto, Motoshi Suzuki, Yoshinori Nozawa, Masatoshi Ichihara & Takashi Murate. (2016) Mechanism of paclitaxel resistance in a human prostate cancer cell line, PC3-PR, and its sensitization by cabazitaxel. Biochemical and Biophysical Research Communications 479:4, pages 808-813.
Crossref
Crossref
Erica K. Cassimere, Claire Mauvais & Catherine Denicourt. (2016) p27Kip1 Is Required to Mediate a G1 Cell Cycle Arrest Downstream of ATM following Genotoxic Stress. PLOS ONE 11:9, pages e0162806.
Crossref
Crossref
YI MA, XUN GONG, YINGLI MO & SAIZHU WU. (2016) Polydatin inhibits the oxidative stress-induced proliferation of vascular smooth muscle cells by activating the eNOS/SIRT1 pathway. International Journal of Molecular Medicine 37:6, pages 1652-1660.
Crossref
Crossref
See-Hyoung Park, Kyu Yun Jang, Min Jae Kim, Sarah Yoon, Yuna Jo, So Mee Kwon, Kyoung Min Kim, Keun Sang Kwon, Chan Young Kim & Hyun Goo Woo. (2015) Tumor suppressive effect of PARP1 and FOXO3A in gastric cancers and its clinical implications. Oncotarget 6:42, pages 44819-44831.
Crossref
Crossref
Byeal-I Han & Michael Lee. (2015) Paclitaxel-Induced G2/M Arrest via Different Mechanism of Actions in Glioma Cell Lines with Differing p53 Mutational Status. International Journal of Pharmacology 12:1, pages 19-27.
Crossref
Crossref
SOMA KUNDU, TAE HYUNG KIM, JUNG HYUN YOON, HAN-SEUNG SHIN, JAEWON LEE, JEE H. JUNG & HYUNG SIK KIM. (2014) Viriditoxin regulates apoptosis and autophagy via mitotic catastrophe and microtubule formation in human prostate cancer cells. International Journal of Oncology 45:6, pages 2331-2340.
Crossref
Crossref
Jana Jezkova, Jason S. Williams, Ffion Jones-Hutchins, Stephen J. Sammut, Simon Gollins, Ian Cree, Sarah Coupland, Ramsay J. McFarlane & Jane A. Wakeman. (2014) Brachyury regulates proliferation of cancer cells via a p27Kip1-dependent pathway. Oncotarget 5:11, pages 3813-3822.
Crossref
Crossref
Snehalata A. Pawar, Lijian Shao, Jianhui Chang, Wenze Wang, Rupak Pathak, Xiaoyan Zhu, Junru Wang, Howard Hendrickson, Marjan Boerma, Esta Sterneck, Daohong Zhou & Martin Hauer-Jensen. (2014) C/EBPδ Deficiency Sensitizes Mice to Ionizing Radiation-Induced Hematopoietic and Intestinal Injury. PLoS ONE 9:4, pages e94967.
Crossref
Crossref
Zan Tong, Huichao Yan & Weihuang Liu. (2014) Interleukin-17F attenuates H2O2-induced cell cycle arrest. Cellular Immunology 287:2, pages 74-77.
Crossref
Crossref
Omar Saeed Ali Al-Salahi, Dan Ji, Amin Malik Shah Abdul Majid, Chan Kit-Lam, Wan Zaidah Abdullah, Abdelhamid Zaki, Shah Kamal Khan Jamal Din, Narazah Mohd Yusoff & Aman Shah Abdul Majid. (2014) Anti-Tumor Activity of Eurycoma longifolia Root Extracts against K-562 Cell Line: In Vitro and In Vivo Study. PLoS ONE 9:1, pages e83818.
Crossref
Crossref
Fon-Chang Liu, Ming-Tsung Lai, Ying-Yi Chen, Wen-Hsin Lin, Shu-Jen Chang, Ming-Jyh Sheu & Chieh-Hsi Wu. (2013) Elucidating the inhibitory mechanisms of the ethanolic extract of the fruiting body of the mushroom Antrodia cinnamomea on the proliferation and migration of murine leukemia WEHI-3 cells and their tumorigenicity in a BALB/c allograft tumor model. Phytomedicine 20:10, pages 874-882.
Crossref
Crossref
Nabanita Patra, Umasankar De, Tae Hyung Kim, Young Ju Lee, Mee Young Ahn, Nam Deuk Kim, Jung Hyun Yoon, Wahn Soo Choi, Hyung Ryong Moon, Byung Mu Lee & Hyung Sik Kim. (2013) A novel histone deacetylase (HDAC) inhibitor MHY219 induces apoptosis via up-regulation of androgen receptor expression in human prostate cancer cells. Biomedicine & Pharmacotherapy 67:5, pages 407-415.
Crossref
Crossref
H Salim, N S Akbar, D Zong, A H Vaculova, R Lewensohn, A Moshfegh, K Viktorsson & B Zhivotovsky. (2012) miRNA-214 modulates radiotherapy response of non-small cell lung cancer cells through regulation of p38MAPK, apoptosis and senescence. British Journal of Cancer 107:8, pages 1361-1373.
Crossref
Crossref
Jeffrey P. Miller, Nancy Yeh, Christoph P. Hofstetter, Doruk Keskin, Andrew S. Goldstein & Andrew Koff. (2012) p27kip1 Protein Levels Reflect a Nexus of Oncogenic Signaling during Cell Transformation. Journal of Biological Chemistry 287:24, pages 19775-19785.
Crossref
Crossref
Murielle P. Serres, Uta Kossatz, Yong Chi, James M. Roberts, Nisar P. Malek & Arnaud Besson. (2012) p27Kip1 controls cytokinesis via the regulation of citron kinase activation. Journal of Clinical Investigation 122:3, pages 844-858.
Crossref
Crossref
Yang Xu, Yick-Pang Ching, Yuan Zhou, Jen-Fu Chiu, Feng Chen & Qing-Yu He. (2011) Multiple pathways were involved in tubeimoside-1-induced cytotoxicity of HeLa cells. Journal of Proteomics 75:2, pages 491-501.
Crossref
Crossref
Brian J. Leibowitz, Wei Qiu, Hongtao Liu, Tao Cheng, Lin Zhang & Jian Yu. (2011) Uncoupling p53 Functions in Radiation-Induced Intestinal Damage via PUMA and p21. Molecular Cancer Research 9:5, pages 616-625.
Crossref
Crossref
D M Heijink, R S N Fehrmann, E G E de Vries, J J Koornstra, D Oosterhuis, A G J van der Zee, J H Kleibeuker & S de Jong. (2011) A bioinformatical and functional approach to identify novel strategies for chemoprevention of colorectal cancer. Oncogene 30:17, pages 2026-2036.
Crossref
Crossref
William K.K. Wu, Chi H. Cho, Chung W. Lee, Daiming Fan, Kaichun Wu, Jun Yu & Joseph J.Y. Sung. (2010) Dysregulation of cellular signaling in gastric cancer. Cancer Letters 295:2, pages 144-153.
Crossref
Crossref
Wei Wang, Quanxi Li, Indrani C. Bagchi & Milan K. Bagchi. (2010) The CCAAT/Enhancer Binding Protein β Is a Critical Regulator of Steroid-Induced Mitotic Expansion of Uterine Stromal Cells during Decidualization. Endocrinology 151:8, pages 3929-3940.
Crossref
Crossref
W L See, J P Miller, M Squatrito, E Holland, M D Resh & A Koff. (2010) Defective DNA double-strand break repair underlies enhanced tumorigenesis and chromosomal instability in p27-deficient mice with growth factor-induced oligodendrogliomas. Oncogene 29:12, pages 1720-1731.
Crossref
Crossref
Myriam Cuadrado, Paula Gutierrez-Martinez, Aneta Swat, Angel R. Nebreda & Oscar Fernandez-Capetillo. (2009) p27Kip1 Stabilization Is Essential for the Maintenance of Cell Cycle Arrest in Response to DNA Damage. Cancer Research 69:22, pages 8726-8732.
Crossref
Crossref
Isidora Ranchal, Raúl González, Rosario I. Bello, Gustavo Ferrín, Ana B. Hidalgo, Clara I. Linares, Patricia Aguilar-Melero, Sandra González-Rubio, Pilar Barrera, Trinidad Marchal, Keiichi I. Nakayama, Manuel de la Mata & Jordi Muntané. (2009)
The reduction of cell death and proliferation by p27
Kip1
minimizes DNA damage in an experimental model of genotoxicity
. International Journal of Cancer 125:10, pages 2270-2280.
Crossref
Crossref
Zhaojian Liu, Qiao Liu, Bing Xu, Jingjing Wu, Chun Guo, Faliang Zhu, Qiaozi Yang, Guimin Gao, Yaoqin Gong & Changshun Shao. (2009) Berberine induces p53-dependent cell cycle arrest and apoptosis of human osteosarcoma cells by inflicting DNA damage. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 662:1-2, pages 75-83.
Crossref
Crossref
M. C. Moh, T. Zhang, L. H. Lee & S. Shen. (2008) Expression of hepaCAM is downregulated in cancers and induces senescence-like growth arrest via a p53/p21-dependent pathway in human breast cancer cells. Carcinogenesis 29:12, pages 2298-2305.
Crossref
Crossref