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Molecular and Cellular Biology Volume 33, 2013 - Issue 9
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Article

The Drosophila Ortholog of MLL3 and MLL4, trithoraxrelated, Functions as a Negative Regulator of Tissue Growth

Hiroshi Kandaa Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California, USA;b Department of Physiology, Keio University School of Medicine, Tokyo, Japan
,
Alexander Nguyena Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California, USA
,
Leslie Chena Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California, USA
,
Hideyuki Okanob Department of Physiology, Keio University School of Medicine, Tokyo, Japan
&
Iswar K. Hariharana Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California, USACorrespondence[email protected]
Pages 1702-1710 | Received 24 Nov 2012, Accepted 22 Feb 2013, Published online: 20 Mar 2023

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Joni Van der Meulen, Frank Speleman & Pieter Van Vlierberghe. (2014) The H3K27me3 demethylase UTX in normal development and disease. Epigenetics 9:5, pages 658-668.
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Marc Alard Morgan & Ali Shilatifard. (2013) Drosophila SETs Its Sights on Cancer: Trr/MLL3/4 COMPASS-Like Complexes in Development and Disease. Molecular and Cellular Biology 33:9, pages 1698-1701.
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Articles from other publishers (32)

Carly S. Golden, Saylor Williams & Maria A. Serrano. (2023) Molecular insights of KMT2D and clinical aspects of Kabuki syndrome type 1. Birth Defects Research.
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Lautaro Gandara, Albert Tsai, Måns Ekelöf, Rafael Galupa, Ella Preger-Ben Noon, Theodore Alexandrov & Justin Crocker. (2022) Developmental phenomics suggests that H3K4 monomethylation confers multi-level phenotypic robustness. Cell Reports 41:11, pages 111832.
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Reza Raeisossadati, Merari F. R. Ferrari, Alexandre Hiroaki Kihara, Issam AlDiri & Jeffrey M. Gross. (2021) Epigenetic regulation of retinal development. Epigenetics & Chromatin 14:1.
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David J. Ford, Claudia B. Zraly, John Hertenstein Perez & Andrew K. Dingwall. (2020) The Drosophila MLR COMPASS-like complex regulates bantam miRNA expression differentially in the context of cell fate. Developmental Biology 468:1-2, pages 41-53.
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Kihyun Park, Jung-Ae Kim & Jaehoon Kim. (2020) Transcriptional regulation by the KMT2 histone H3K4 methyltransferases. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1863:7, pages 194545.
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Claudia B Zraly, Abdul Zakkar, John Hertenstein Perez, Jeffrey Ng, Kevin P White, Matthew Slattery & Andrew K Dingwall. (2020) The Drosophila MLR COMPASS complex is essential for programming cis-regulatory information and maintaining epigenetic memory during development. Nucleic Acids Research 48:7, pages 3476-3495.
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Nicholas T. Crump & Thomas A. Milne. (2019) Why are so many MLL lysine methyltransferases required for normal mammalian development?. Cellular and Molecular Life Sciences 76:15, pages 2885-2898.
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Ryan Rickels, Hans-Martin Herz, Christie C Sze, Kaixiang Cao, Marc A Morgan, Clayton K Collings, Maria Gause, Yoh-hei Takahashi, Lu Wang, Emily J Rendleman, Stacy A Marshall, Annika Krueger, Elizabeth T Bartom, Andrea Piunti, Edwin R Smith, Nebiyu A Abshiru, Neil L Kelleher, Dale Dorsett & Ali Shilatifard. (2017) Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability. Nature Genetics 49:11, pages 1647-1653.
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Yin-Cheng Huang, Sheng-Jia Lin, Hung-Yu Shih, Chung-Han Chou, Hsiao-Han Chu, Ching-Chi Chiu, Chiou-Hwa Yuh, Tu-Hsueh Yeh & Yi-Chuan Cheng. (2017) Epigenetic regulation of NOTCH1 and NOTCH3 by KMT2A inhibits glioma proliferation. Oncotarget 8:38, pages 63110-63120.
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Hans-Martin Herz. (2016) Enhancer deregulation in cancer and other diseases. BioEssays 38:10, pages 1003-1015.
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Deqing Hu & Ali Shilatifard. (2016) Epigenetics of hematopoiesis and hematological malignancies. Genes & Development 30:18, pages 2021-2041.
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Joshua B.N. Dawkins, Jun Wang, Eleni Maniati, James A. Heward, Lola Koniali, Hemant M. Kocher, Sarah A. Martin, Claude Chelala, Frances R. Balkwill, Jude Fitzgibbon & Richard P. Grose. (2016) Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma. Cancer Research 76:16, pages 4861-4871.
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Andrea Skinner, Sumbul Jawed Khan & Rachel K. Smith-Bolton. (2015) Trithorax regulates systemic signaling during Drosophila imaginal disc regeneration . Development 142:20, pages 3500-3511.
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Rajesh C. Rao & Yali Dou. (2015) Hijacked in cancer: the KMT2 (MLL) family of methyltransferases. Nature Reviews Cancer 15:6, pages 334-346.
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David J. Ford & Andrew K. Dingwall. (2015) The cancer COMPASS: navigating the functions of MLL complexes in cancer. Cancer Genetics 208:5, pages 178-191.
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Joseph Sinkovics. (2015) The cell survival pathways of the primordial RNA-DNA complex remain conserved in the extant genomes and may function as proto-oncogenes. European Journal of Microbiology and Immunology 5:1, pages 25-43.
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Shuhei Kimura & Benjamin Loppin. (2015) Two bromodomain proteins functionally interact to recapitulate an essential BRDT-like function in Drosophila spermatocytes . Open Biology 5:2, pages 140145.
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Ming Tang, Huacheng Luo & Jianrong Lu. 2015. Epigenetic Gene Expression and Regulation. Epigenetic Gene Expression and Regulation 265 289 .
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Yun Qing, Feng Yin, Wei Wang, Yonggang Zheng, Pengfei Guo, Frederick Schozer, Hua Deng & Duojia Pan. (2014) The Hippo effector Yorkie activates transcription by interacting with a histone methyltransferase complex through Ncoa6. eLife 3.
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Hyangyee Oh, Matthew Slattery, Lijia Ma, Kevin P. White, Richard S. Mann & Kenneth D. Irvine. (2014) Yorkie Promotes Transcription by Recruiting a Histone Methyltransferase Complex. Cell Reports 8:2, pages 449-459.
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Edwin Smith & Ali Shilatifard. (2014) Enhancer biology and enhanceropathies. Nature Structural & Molecular Biology 21:3, pages 210-219.
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Hans-Martin Herz, Deqing Hu & Ali Shilatifard. (2014) Enhancer Malfunction in Cancer. Molecular Cell 53:6, pages 859-866.
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Chhavi Chauhan, Claudia B. Zraly & Andrew K. Dingwall. (2013) The Drosophila COMPASS-like Cmi-Trr coactivator complex regulates dpp/BMP signaling in pattern formation. Developmental Biology 380:2, pages 185-198.
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