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Article

Motor Protein Myo1c Is a Podocyte Protein That Facilitates the Transport of Slit Diaphragm Protein Neph1 to the Podocyte Membrane

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Pages 2134-2150 | Received 11 Jan 2011, Accepted 02 Mar 2011, Published online: 20 Mar 2023

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Ehtesham Arif, Pankaj Sharma, Ashish Solanki, Leena Mallik, Yogendra S. Rathore, Waleed O. Twal, Samir K. Nath, Darpan Gandhi, Lawrence B. Holzman, E. Michael Ostap, Ashish & Deepak Nihalani. (2016) Structural Analysis of the Myo1c and Neph1 Complex Provides Insight into the Intracellular Movement of Neph1. Molecular and Cellular Biology 36:11, pages 1639-1654.
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Hemma Brandstaetter, Chieko Kishi-Itakura, David A Tumbarello, Dietmar J Manstein & Folma Buss. (2014) Loss of functional MYO1C/myosin 1c, a motor protein involved in lipid raft trafficking, disrupts autophagosome-lysosome fusion. Autophagy 10:12, pages 2310-2323.
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Hemma Brandstaetter, John Kendrick-Jones & Folma Buss. (2012) Molecular roles of Myo1c function in lipid raft exocytosis. Communicative & Integrative Biology 5:5, pages 508-510.
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Lynne M. Coluccio. 2020. Myosins. Myosins 245 316 .
Yoo-Seung Ko, Jeong A. Bae, Keon Young Kim, Sung Jin Kim, Eun Gene Sun, Kyung Hwa Lee, Nacksung Kim, Hyuno Kang, Young-Woo Seo, Hangun Kim, Ik Joo Chung & Kyung Keun Kim. (2019) MYO1D binds with kinase domain of the EGFR family to anchor them to plasma membrane before their activation and contributes carcinogenesis. Oncogene 38:49, pages 7416-7432.
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Jeong Suk Kang, Seung Joo Lee, Ji-Hye Lee, Ji-Hee Kim, Seung Seob Son, Seung-Kuy Cha, Eun Soo Lee, Choon Hee Chung & Eun Young Lee. (2019) Angiotensin II-mediated MYH9 downregulation causes structural and functional podocyte injury in diabetic kidney disease. Scientific Reports 9:1.
Crossref
Ehtesham Arif & Deepak Nihalani. (2019) Beta2‐adrenergic receptor in kidney biology: A current prospective. Nephrology 24:5, pages 497-503.
Crossref
Daniel Alberto Girón-Pérez, Zayda Lizbeth Piedra-Quintero & Leopoldo Santos-Argumedo. (2019) Class I myosins: Highly versatile proteins with specific functions in the immune system. Journal of Leukocyte Biology 105:5, pages 973-981.
Crossref
Jun Jiang, Jiangning Yin, Xiang Liu, Huajun Wang & Guoyuan Lu. (2018) Erzhi Formula Extracts Reverse Renal Injury in Diabetic Nephropathy Rats by Protecting the Renal Podocytes. Evidence-Based Complementary and Alternative Medicine 2018, pages 1-13.
Crossref
Claire E. Martin & Nina Jones. (2018) Nephrin Signaling in the Podocyte: An Updated View of Signal Regulation at the Slit Diaphragm and Beyond. Frontiers in Endocrinology 9.
Crossref
Bhavya Khullar, Renu Balyan, Neelam Oswal, Nidhi Jain, Amita Sharma, Malik Z. Abdin, Arvind Bagga, Shinjini Bhatnagar, Nitya Wadhwa, Uma Chandra Mouli Natchu, Anna George, Satyajit Rath, Vineeta Bal & Shailaja Sopory. (2017) Interaction of CD80 with Neph1: a potential mechanism of podocyte injury. Clinical and Experimental Nephrology 22:3, pages 508-516.
Crossref
Nivetha Kannan & Vivian W. Tang. (2018) Myosin-1c promotes E-cadherin tension and force-dependent recruitment of α-actinin-4 to the epithelial cell junction. Journal of Cell Science.
Crossref
Ivan V. Maly, Tera M. Domaradzki, Victoria A. Gosy & Wilma A. Hofmann. (2017) Myosin isoform expressed in metastatic prostate cancer stimulates cell invasion. Scientific Reports 7:1.
Crossref
Juan Carlos Q. Velez, Ehtesham Arif, Jessalyn Rodgers, Megan P. Hicks, John M. Arthur, Deepak Nihalani, Evelyn T. Bruner, Milos N. Budisavljevic, Carl Atkinson, Wayne R. Fitzgibbon & Michael G. Janech. (2017) Deficiency of the Angiotensinase Aminopeptidase A Increases Susceptibility to Glomerular Injury. Journal of the American Society of Nephrology 28:7, pages 2119-2132.
Crossref
Wilhelm Kriz & Kevin V. Lemley. (2016) Mechanical challenges to the glomerular filtration barrier: adaptations and pathway to sclerosis. Pediatric Nephrology 32:3, pages 405-417.
Crossref
Agnieszka Swiatecka-Urban. (2017) Endocytic Trafficking at the Mature Podocyte Slit Diaphragm. Frontiers in Pediatrics 5.
Crossref
Luca Perico, Sara Conti, Ariela Benigni & Giuseppe Remuzzi. (2016) Podocyte–actin dynamics in health and disease. Nature Reviews Nephrology 12:11, pages 692-710.
Crossref
Kittichate Visuttijai, Jennifer Pettersson, Yashar Mehrbani Azar, Iman van den Bout, Charlotte Örndal, Janusz Marcickiewicz, Staffan Nilsson, Michael Hörnquist, Björn Olsson, Katarina Ejeskär & Afrouz Behboudi. (2016) Lowered Expression of Tumor Suppressor Candidate MYO1C Stimulates Cell Proliferation, Suppresses Cell Adhesion and Activates AKT. PLOS ONE 11:10, pages e0164063.
Crossref
Antonina J. Kruppa, John Kendrick‐Jones & Folma Buss. (2016) Myosins, Actin and Autophagy. Traffic 17:8, pages 878-890.
Crossref
William’s Elong Edimo, Ana Raquel Ramos, Somadri Ghosh, Jean-Marie Vanderwinden & Christophe Erneux. (2016) The SHIP2 interactor Myo1c is required for cell migration in 1321 N1 glioblastoma cells. Biochemical and Biophysical Research Communications 476:4, pages 508-514.
Crossref
Serapion Pyrpassopoulos, Göker Arpağ, Elizabeth A. Feeser, Henry Shuman, Erkan Tüzel & E. Michael Ostap. (2016) Force Generation by Membrane-Associated Myosin-I. Scientific Reports 6:1.
Crossref
Jochen Reiser & Mehmet M. Altintas. (2016) Podocytes. F1000Research 5, pages 114.
Crossref
Betsy B. McIntosh & E. Michael Ostap. (2016) Myosin-I molecular motors at a glance. Journal of Cell Science.
Crossref
Merja Joensuu & Eija Jokitalo. (2015) ER sheet–tubule balance is regulated by an array of actin filaments and microtubules. Experimental Cell Research 337:2, pages 170-178.
Crossref
Kazunori Inoue & Shuta Ishibe. (2015) Podocyte endocytosis in the regulation of the glomerular filtration barrier. American Journal of Physiology-Renal Physiology 309:5, pages F398-F405.
Crossref
Hui Bao, Yan Ge, Ai Peng & Rujun Gong. (2015) Fine-tuning of NFκB by glycogen synthase kinase 3β directs the fate of glomerular podocytes upon injury. Kidney International 87:6, pages 1176-1190.
Crossref
Simona Buelli, Luca Perico, Miriam Galbusera, Mauro Abbate, Marina Morigi, Rubina Novelli, Elena Gagliardini, Chiara Tentori, Daniela Rottoli, Ettore Sabadini, Takao Saito, Mitsuhiro Kawano, Takako Saeki, Carlamaria Zoja, Giuseppe Remuzzi & Ariela Benigni. (2015) Mitochondrial-dependent Autoimmunity in Membranous Nephropathy of IgG4-related Disease. EBioMedicine 2:5, pages 456-466.
Crossref
Chris R. Neal. (2015) Podocytes … What’s Under Yours? (Podocytes and Foot Processes and How They Change in Nephropathy). Frontiers in Endocrinology 6.
Crossref
Wilhelm Kriz & Kevin V. Lemley. (2015) A Potential Role for Mechanical Forces in the Detachment of Podocytes and the Progression of CKD. Journal of the American Society of Nephrology 26:2, pages 258-269.
Crossref
Jing Bi, Robert T. Carroll, Michael L. James, Jessica L. Ouderkirk, Mira Krendel & Vladimir Sirotkin. (2015) Effects of FSGS-associated mutations on the stability and function of myosin-1 in fission yeast. Disease Models & Mechanisms.
Crossref
Qing Lu, Jianchao Li, Fei Ye & Mingjie Zhang. (2014) Structure of myosin-1c tail bound to calmodulin provides insights into calcium-mediated conformational coupling. Nature Structural & Molecular Biology 22:1, pages 81-88.
Crossref
Rachel Lennon, Michael J. Randles & Martin J. Humphries. (2014) The Importance of Podocyte Adhesion for a Healthy Glomerulus. Frontiers in Endocrinology 5.
Crossref
Laura A. New, Claire E. Martin & Nina Jones. (2014) Advances in slit diaphragm signaling. Current Opinion in Nephrology and Hypertension 23:4, pages 420-430.
Crossref
Stefan Münnich, Manuel H. Taft & Dietmar J. Manstein. (2014) Crystal Structure of Human Myosin 1c—The Motor in GLUT4 Exocytosis: Implications for Ca2+ Regulation and 14-3-3 Binding. Journal of Molecular Biology 426:10, pages 2070-2081.
Crossref
Ehtesham Arif, Yogendra S. Rathore, Babita Kumari, Fnu Ashish, Hetty N. Wong, Lawrence B. Holzman & Deepak Nihalani. (2014) Slit Diaphragm Protein Neph1 and Its Signaling. Journal of Biological Chemistry 289:14, pages 9502-9518.
Crossref
Ehtesham Arif, Babita Kumari, Mark C. Wagner, Weibin Zhou, Lawrence B. Holzman & Deepak Nihalani. (2013) Myo1c is an unconventional myosin required for zebrafish glomerular development. Kidney International 84:6, pages 1154-1165.
Crossref
Florian Grahammer, Christoph Schell & Tobias B. Huber. (2013) The podocyte slit diaphragm—from a thin grey line to a complex signalling hub. Nature Reviews Nephrology 9:10, pages 587-598.
Crossref
Hiroshi Tokuo & Lynne M. Coluccio. (2013) Myosin-1c regulates the dynamic stability of E-cadherin–based cell–cell contacts in polarized Madin–Darby canine kidney cells. Molecular Biology of the Cell 24:18, pages 2820-2833.
Crossref
J. BiS. E. ChaseC. D. PellenzH. Kurihara, A. S. Fanning & M. Krendel. (2013) Myosin 1e is a component of the glomerular slit diaphragm complex that regulates actin reorganization during cell-cell contact formation in podocytes. American Journal of Physiology-Renal Physiology 305:4, pages F532-F544.
Crossref
Tomáš Venit, Rastislav Dzijak, Alžběta Kalendová, Michal Kahle, Jana Rohožková, Volker Schmidt, Thomas Rülicke, Birgit Rathkolb, Wolfgang Hans, Alexander Bohla, Oliver Eickelberg, Tobias Stoeger, Eckhard Wolf, Ali Önder Yildirim, Valérie Gailus-Durner, Helmut Fuchs, Martin Hrabě de Angelis & Pavel Hozák. (2013) Mouse Nuclear Myosin I Knock-Out Shows Interchangeability and Redundancy of Myosin Isoforms in the Cell Nucleus. PLoS ONE 8:4, pages e61406.
Crossref
Ajit TiwariJae-Joon JungShivangi M. InamdarDeepak NihalaniAmit Choudhury. (2013) The myosin motor Myo1c is required for VEGFR2 delivery to the cell surface and for angiogenic signaling. American Journal of Physiology-Heart and Circulatory Physiology 304:5, pages H687-H696.
Crossref
Michael J. Greenberg & E. Michael Ostap. (2013) Regulation and control of myosin-I by the motor and light chain-binding domains. Trends in Cell Biology 23:2, pages 81-89.
Crossref
Lisa M. Bond, Hemma Brandstaetter, John Kendrick-Jones & Folma Buss. (2013) Functional roles for myosin 1c in cellular signaling pathways. Cellular Signalling 25:1, pages 229-235.
Crossref
Sharon E. ChaseChristina V. EncinaLindsay R. StolzenburgArthur H. Tatum, Lawrence B. Holzman & Mira Krendel. (2012) Podocyte-specific knockout of myosin 1e disrupts glomerular filtration. American Journal of Physiology-Renal Physiology 303:7, pages F1099-F1106.
Crossref
Yi Fan, Sandeepa M. Eswarappa, Masahiro Hitomi & Paul L. Fox. (2012) Myo1c facilitates G-actin transport to the leading edge of migrating endothelial cells. Journal of Cell Biology 198:1, pages 47-55.
Crossref
Britta George & Lawrence B. Holzman. (2012) Signaling From the Podocyte Intercellular Junction to the Actin Cytoskeleton. Seminars in Nephrology 32:4, pages 307-318.
Crossref
Puneet Garg & Lawrence B. Holzman. (2012) Podocytes: Gaining a foothold. Experimental Cell Research 318:9, pages 955-963.
Crossref
M. Noris & G. Remuzzi. (2012) Non-muscle myosins and the podocyte. Clinical Kidney Journal 5:2, pages 94-101.
Crossref
Leena Mallik, Ehtesham Arif, Pankaj Sharma, Yogendra S. Rathore, Hetty N. Wong, Lawrence B. Holzman, Ashish & Deepak Nihalani. (2012) Solution Structure Analysis of Cytoplasmic Domain of Podocyte Protein Neph1 Using Small/Wide Angle X-ray Scattering (SWAXS). Journal of Biological Chemistry 287:12, pages 9441-9453.
Crossref
Britta George, Rakesh Verma, Abdulsalam A. Soofi, Puneet Garg, Jidong Zhang, Tae-Ju Park, Laura Giardino, Larisa Ryzhova, Duncan B. Johnstone, Hetty Wong, Deepak Nihalani, David J. Salant, Steven K. Hanks, Tom Curran, Maria Pia Rastaldi & Lawrence B. Holzman. (2012) Crk1/2-dependent signaling is necessary for podocyte foot process spreading in mouse models of glomerular disease. Journal of Clinical Investigation 122:2, pages 674-692.
Crossref
Hemma Brandstaetter, John Kendrick-Jones & Folma Buss. (2012) Myo1c regulates lipid raft recycling to control cell spreading, migration and Salmonella invasion . Journal of Cell Science.
Crossref

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