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Article

PinX1 Localizes to Telomeres and Stabilizes TRF1 at Mitosis

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Pages 1387-1395 | Received 15 May 2011, Accepted 31 Jan 2012, Published online: 20 Mar 2023

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Erjiong Huang, Ke Xu, Xuemei Gu & Qihan Zhu. (2021) PinX1 Depletion Improves Liver Injury in a Mouse Model of Nonalcoholic Fatty Liver Disease via Increasing Telomerase Activity and Inhibiting Apoptosis. Cytogenetic and Genome Research 161:8-9, pages 449-462.
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Hing Chung Chan, Yuen Ting Lau, Qianqian Ding, Chun Kit Li, Chi Ming Wong, Pang Chui Shaw, Mary Miu Yee Waye & Suk Ying Tsang. (2020) PinX1t, a Novel PinX1 Transcript Variant, Positively Regulates Cardiogenesis of Embryonic Stem Cells. Journal of the American Heart Association 9:6.
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Lifan Liang, Vicky Chen, Kunju Zhu, Xiaonan Fan, Xinghua Lu & Songjian Lu. (2019) Integrating data and knowledge to identify functional modules of genes: a multilayer approach. BMC Bioinformatics 20:1.
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Maria Alejandra Viviescas, Maria Isabel Nogueira Cano & Marcela Segatto. (2018) Chaperones and Their Role in Telomerase Ribonucleoprotein Biogenesis and Telomere Maintenance. Current Proteomics 16:1, pages 31-43.
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Hao Liang, Zhiyong Xiong, Ying Li, Weihao Kong, Zhicheng Yao, Ruixi Li, Meihai Deng & Kunpeng Hu. (2018) Prognostic and Clinicopathological Value of PINX1 in Various Human Tumors: A Meta-Analysis . BioMed Research International 2018, pages 1-10.
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Xiao-Peng Tian, Xiao-Han Jin, Mei Li, Wei-Juan Huang, Dan Xie & Jia-Xing Zhang. (2017) The depletion of PinX1 involved in the tumorigenesis of non-small cell lung cancer promotes cell proliferation via p15/cyclin D1 pathway. Molecular Cancer 16:1.
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Romina Burla, Mariateresa Carcuro, Grazia D. Raffa, Alessandra Galati, Domenico Raimondo, Angela Rizzo, Mattia La Torre, Emanuela Micheli, Laura Ciapponi, Giovanni Cenci, Enrico Cundari, Antonio Musio, Annamaria Biroccio, Stefano Cacchione, Maurizio Gatti & Isabella Saggio. (2015) AKTIP/Ft1, a New Shelterin-Interacting Factor Required for Telomere Maintenance. PLOS Genetics 11:6, pages e1005167.
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Peng-Jin Mei, Yan-Su Chen, Ying Du, Jin Bai & Jun-Nian Zheng. (2015) PinX1 inhibits cell proliferation, migration and invasion in glioma cells. Medical Oncology 32:3.
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Xiao-Peng Tian, Dong Qian, Li-Ru He, He Huang, Shi-Juan Mai, Chang-Peng Li, Xiao-Xia Huang, Mu-Yan Cai, Yi-Ji Liao, Hsiang-fu Kung, Yi-Xin Zeng & Dan Xie. (2014) The telomere/telomerase binding factor PinX1 regulates paclitaxel sensitivity depending on spindle assembly checkpoint in human cervical squamous cell carcinomas. Cancer Letters 353:1, pages 104-114.
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Jianping Lan, Yuanyuan Zhu, Leilei Xu, Huijuan Yu, Jian Yu, Xing Liu, Chuanhai Fu, Xiaogang Wang, Yuwen Ke, He Huang & Zhen Dou. (2014) The 68-kDa Telomeric Repeat Binding Factor 1 (TRF1)-associated Protein (TAP68) Interacts with and Recruits TRF1 to the Spindle Pole during Mitosis. Journal of Biological Chemistry 289:20, pages 14145-14156.
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Jeong Eun Yoo, Young Nyun Park & Bong-Kyeong Oh. (2014) PinX1, a Telomere Repeat-binding Factor 1 (TRF1)-interacting Protein, Maintains Telomere Integrity by Modulating TRF1 Homeostasis, the Process in Which Human Telomerase Reverse Transcriptase (hTERT) Plays Dual Roles. Journal of Biological Chemistry 289:10, pages 6886-6898.
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Gengze Wu, Dongbo Liu, Ke Jiang, Li Zhang, Yijun Zeng, Peng Zhou, Dan Zhong, Min Gao, Fengtian He & Yingru Zheng. (2014) PinX1, a novel target gene of p53, is suppressed by HPV16 E6 in cervical cancer cells. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1839:2, pages 88-96.
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Jonathan D. Mosley, Sara L. Van Driest, Emma K. Larkin, Peter E. Weeke, John S. Witte, Quinn S. Wells, Jason H. Karnes, Yan Guo, Lisa Bastarache, Lana M. Olson, Catherine A. McCarty, Jennifer A. Pacheco, Gail P. Jarvik, David S. Carrell, Eric B. Larson, David R. Crosslin, Iftikhar J. Kullo, Gerard Tromp, Helena Kuivaniemi, David J. Carey, Marylyn D. Ritchie, Josh C. Denny & Dan M. Roden. (2013) Mechanistic Phenotypes: An Aggregative Phenotyping Strategy to Identify Disease Mechanisms Using GWAS Data. PLoS ONE 8:12, pages e81503.
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Despoina Sakellariou, Maria Chiourea, Christina Raftopoulou & Sarantis Gagos. (2013) Alternative Lengthening of Telomeres: Recurrent Cytogenetic Aberrations and Chromosome Stability under Extreme Telomere Dysfunction. Neoplasia 15:11, pages 1301-1313.
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Shuqun Yang & Christopher M. Counter. (2013) Cell Cycle Regulated Phosphorylation of the Telomere-Associated Protein TIN2. PLoS ONE 8:8, pages e71697.
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