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Molecular and Cellular Biology Volume 32, 2012 - Issue 2
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Article

The RecQ4 Orthologue Hrq1 Is Critical for DNA Interstrand Cross-Link Repair and Genome Stability in Fission Yeast

Lynda M. Groococka Department of Molecular Biology, The Scripps Research Institute, La Jolla, California, USA
,
John Pruddena Department of Molecular Biology, The Scripps Research Institute, La Jolla, California, USA
,
J. Jefferson P. Perrya Department of Molecular Biology, The Scripps Research Institute, La Jolla, California, USA;b School of Biotechnology, Amrita University, Kollam, Kerala, India
&
Michael N. Boddya Department of Molecular Biology, The Scripps Research Institute, La Jolla, California, USACorrespondence[email protected]
Pages 276-287 | Received 26 Aug 2011, Accepted 25 Oct 2011, Published online: 20 Mar 2023

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Nafees Ahamad, Saman Khan & Yong-jie Xu. (2020) RecQ DNA Helicase Rqh1 Promotes Rad3ATR Kinase Signaling in the DNA Replication Checkpoint Pathway of Fission Yeast. Molecular and Cellular Biology 40:17.
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Matthew L Bochman. (2014) Roles of DNA helicases in the maintenance of genome integrity. Molecular & Cellular Oncology 1:3.
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Articles from other publishers (26)

Thong T. Luong, Zheqi Li, Nolan Priedigkeit, Phoebe S. Parker, Stefanie Böhm, Kyle Rapchak, Adrian V. Lee & Kara A. Bernstein. (2022) Hrq1/RECQL4 regulation is critical for preventing aberrant recombination during DNA intrastrand crosslink repair and is upregulated in breast cancer. PLOS Genetics 18:9, pages e1010122.
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Nafees Ahamad, Saman Khan, Alaa Taha A. Mahdi & Yong-jie Xu. (2021) Checkpoint functions of RecQ helicases at perturbed DNA replication fork. Current Genetics 67:3, pages 369-382.
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Cody M. Rogers, Robert H. Simmons III, Gabriella E. Fluhler Thornburg, Nicholas J. Buehler & Matthew L. Bochman. (2020) Fanconi anemia-independent DNA inter-strand crosslink repair in eukaryotes. Progress in Biophysics and Molecular Biology 158, pages 33-46.
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Cody M. Rogers, Chun-Ying Lee, Samuel Parkins, Nicholas J. Buehler, Sabine Wenzel, Francisco Martínez-Márquez, Yuichiro Takagi, Sua Myong & Matthew L. Bochman. (2020) The yeast Hrq1 helicase stimulates Pso2 translesion nuclease activity and thereby promotes DNA interstrand crosslink repair. Journal of Biological Chemistry 295:27, pages 8945-8957.
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Masaoki Kohzaki, Akira Ootsuyama, Lue Sun, Takashi Moritake & Ryuji Okazaki. (2020) Human RECQL4 represses the RAD52‐mediated single‐strand annealing pathway after ionizing radiation or cisplatin treatment. International Journal of Cancer 146:11, pages 3098-3113.
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Sonia Vidushi Gupta & Kristina Hildegard Schmidt. (2020) Maintenance of Yeast Genome Integrity by RecQ Family DNA Helicases. Genes 11:2, pages 205.
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Annika Dorn & Holger Puchta. (2019) DNA Helicases as Safekeepers of Genome Stability in Plants. Genes 10:12, pages 1028.
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Justin L. Sparks, Kimberly J. Gerik, Carrie M. Stith, Bonita L. Yoder & Peter M. Burgers. (2019) The roles of fission yeast exonuclease 5 in nuclear and mitochondrial genome stability. DNA Repair 83, pages 102720.
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Abantika Ganguly, Lan Guo, Lingling Sun, Fang Suo, Li-Lin Du & Paul Russell. (2018) Tdp1 processes chromate-induced single-strand DNA breaks that collapse replication forks. PLOS Genetics 14:8, pages e1007595.
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Sarah Röhrig, Annika Dorn, Janina Enderle, Angelina Schindele, Natalie J. Herrmann, Alexander Knoll & Holger Puchta. (2018) The RecQ-like helicase HRQ1 is involved in DNA crosslink repair in Arabidopsis in a common pathway with the Fanconi anemia-associated nuclease FAN1 and the postreplicative repair ATPase RAD5A. New Phytologist 218:4, pages 1478-1490.
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Cody M. Rogers & Matthew L. Bochman. (2017) Saccharomyces cerevisiae Hrq1 helicase activity is affected by the sequence but not the length of single-stranded DNA. Biochemical and Biophysical Research Communications 486:4, pages 1116-1121.
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Maciej Kliszczak, Hana Sedlackova, Ganesha P. Pitchai, Werner W. Streicher, Lumir Krejci & Ian D. Hickson. (2015) Interaction of RECQ4 and MCM10 is important for efficient DNA replication origin firing in human cells. Oncotarget 6:38, pages 40464-40479.
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Rathindra N. Bose, Shadi Moghaddas, Louiza Belkacemi, Swarnendu Tripathi, Nyssa R. Adams, Pooja Majmudar, Kelly McCall, Homa Dezvareh & Corey Nislow. (2015) Absence of Activation of DNA Repair Genes and Excellent Efficacy of Phosphaplatins against Human Ovarian Cancers: Implications To Treat Resistant Cancers. Journal of Medicinal Chemistry 58:21, pages 8387-8401.
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Gizem Ölmezer, Dominique Klein & Ulrich Rass. (2015) DNA repair defects ascribed to pby1 are caused by disruption of Holliday junction resolvase Mus81-Mms4. DNA Repair 33, pages 17-23.
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Arancha Sánchez, Assen Roguev, Nevan J Krogan & Paul Russell. (2015) Genetic Interaction Landscape Reveals Critical Requirements for Schizosaccharomyces pombe Brc1 in DNA Damage Response Mutants . G3 Genes|Genomes|Genetics 5:5, pages 953-962.
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Heidi Keller, Kristin Kiosze, Juliane Sachsenweger, Sebastian Haumann, Oliver Ohlenschläger, Tarmo Nuutinen, Juhani E. Syväoja, Matthias Görlach, Frank Grosse & Helmut Pospiech. (2014) The intrinsically disordered amino-terminal region of human RecQL4: multiple DNA-binding domains confer annealing, strand exchange and G4 DNA binding. Nucleic Acids Research 42:20, pages 12614-12627.
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Hana Jung, Jin A Lee, Seoyoon Choi, Hyunwoo Lee & Byungchan Ahn. (2014) Characterization of the Caenorhabditis elegans HIM-6/BLM Helicase: Unwinding Recombination Intermediates. PLoS ONE 9:7, pages e102402.
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Moon-Hee Min, Min-Ji Kim, You-Jin Choi, Min-Ju You, Uy-Ra Kim, Hyo-Bin An, Chae-Hyun Kim, Chae-Yeon Kwon & Sung-Ho Bae. (2014) Characterization of Hrq1-Rad14 Interaction in Saccharomyces cerevisiae. The Korean Journal of Microbiology 50:2, pages 95-100.
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Deborah L. CroteauVenkateswarlu PopuriPatricia L. Opresko & Vilhelm A. Bohr. (2014) Human RecQ Helicases in DNA Repair, Recombination, and Replication. Annual Review of Biochemistry 83:1, pages 519-552.
Crossref
Do-Hee Choi, Moon-Hee Min, Min-Ji Kim, Rina Lee, Sung-Hun Kwon & Sung-Ho Bae. (2014) Hrq1 facilitates nucleotide excision repair of DNA damage induced by 4-nitroquinoline-1-oxide and cisplatin in Saccharomyces cerevisiae. Journal of Microbiology 52:4, pages 292-298.
Crossref
Lin Li, Xiao Hu, Yongliang Xia, Guohua Xiao, Peng Zheng & Chengshu Wang. (2014) Linkage of Oxidative Stress and Mitochondrial Dysfunctions to Spontaneous Culture Degeneration in Aspergillus nidulans. Molecular & Cellular Proteomics 13:2, pages 449-461.
Crossref
Matthew L. Bochman, Katrin Paeschke, Angela Chan & Virginia A. Zakian. (2014) Hrq1, a Homolog of the Human RecQ4 Helicase, Acts Catalytically and Structurally to Promote Genome Integrity. Cell Reports 6:2, pages 346-356.
Crossref
John C. Dittmar, Steven Pierce, Rodney Rothstein & Robert J. D. Reid. (2013) Physical and genetic-interaction density reveals functional organization and informs significance cutoffs in genome-wide screens. Proceedings of the National Academy of Sciences 110:18, pages 7389-7394.
Crossref
Do-Hee Choi, Rina Lee, Sung-Hun Kwon & Sung-Ho Bae. (2013) Hrq1 functions independently of Sgs1 to preserve genome integrity in Saccharomyces cerevisiae. Journal of Microbiology 51:1, pages 105-112.
Crossref
Sung-Hun Kwon, Do-Hee Choi, Rina Lee & Sung-Ho Bae. (2012) Saccharomyces cerevisiae Hrq1 requires a long 3′-tailed DNA substrate for helicase activity. Biochemical and Biophysical Research Communications 427:3, pages 623-628.
Crossref
Lyudmila Yakovleva & Stewart Shuman. (2012) Mycobacterium smegmatis SftH exemplifies a distinctive clade of superfamily II DNA-dependent ATPases with 3′ to 5′ translocase and helicase activities. Nucleic Acids Research 40:15, pages 7465-7475.
Crossref

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