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Molecular and Cellular Biology Volume 15, 1995 - Issue 10
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Research Article

Segregation of Unreplicated Chromosomes in Saccharomyces cerevisiae Reveals a Novel G1/M-Phase Checkpoint

Jeremy H. ToynLaboratory of Yeast Genetics, National Institute for Medical Research, Mill Hill, LondonNW7 1AA, United Kingdom
,
Anthony L. JohnsonLaboratory of Yeast Genetics, National Institute for Medical Research, Mill Hill, LondonNW7 1AA, United Kingdom
&
Leland H. JohnstonLaboratory of Yeast Genetics, National Institute for Medical Research, Mill Hill, LondonNW7 1AA, United Kingdom
Pages 5312-5321 | Received 08 Feb 1995, Accepted 12 Jul 1995, Published online: 30 Mar 2023

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Jenn Hui Khong, Tao Zhang, Jayantha Gunaratne, Walter Blackstock & Uttam Surana. (2012) “Reductional anaphase” in replication-defective cells is caused by ubiquitin-conjugating enzyme Cdc34-mediated deregulation of the spindle. Cell Cycle 11:15, pages 2896-2910.
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Penny A. Tavormina, Yanchang Wang & Daniel J. Burke. (1997) Differential Requirements for DNA Replication in the Activation of Mitotic Checkpoints in Saccharomyces cerevisiae. Molecular and Cellular Biology 17:6, pages 3315-3322.
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Articles from other publishers (33)

Maria Azzopardi, Gianluca Farrugia & Rena Balzan. (2017) Cell-cycle involvement in autophagy and apoptosis in yeast. Mechanisms of Ageing and Development 161, pages 211-224.
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Remi Sonneville, Gillian Craig, Karim Labib, Anton Gartner & J. Julian Blow. (2015) Both Chromosome Decondensation and Condensation Are Dependent on DNA Replication in C. elegans Embryos. Cell Reports 12:3, pages 405-417.
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R. A. SclafaniT. M. Holzen. (2007) Cell Cycle Regulation of DNA Replication. Annual Review of Genetics 41:1, pages 237-280.
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Ted Weinert. (2007) What a Cell Should Know (But May Not). Science 315:5817, pages 1374-1375.
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Andreas Hochwagen & Angelika Amon. (2006) Checking Your Breaks: Surveillance Mechanisms of Meiotic Recombination. Current Biology 16:6, pages R217-R228.
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Martin Weinberger, Lakshmi Ramachandran, Li Feng, Karuna Sharma, Xiaolei Sun, Maria Marchetti, Joel A. Huberman & William C. Burhans. (2005) Apoptosis in budding yeast caused by defects in initiation of DNA replication. Journal of Cell Science 118:15, pages 3543-3553.
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Vincent Archambault, Caihong X. Li, Alan J. Tackett, Ralph Wäsch, Brian T. Chait, Michael P. Rout & Frederick R. Cross. (2003) Genetic and Biochemical Evaluation of the Importance of Cdc6 in Regulating Mitotic Exit. Molecular Biology of the Cell 14:11, pages 4592-4604.
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Alexander J. Osborn & Stephen J. Elledge. (2003) Mrc1 is a replication fork component whose phosphorylation in response to DNA replication stress activates Rad53. Genes & Development 17:14, pages 1755-1767.
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José Antonio Tercero, Maria Pia Longhese & John F.X Diffley. (2003) A Central Role for DNA Replication Forks in Checkpoint Activation and Response. Molecular Cell 11:5, pages 1323-1336.
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W C Burhans, Frederic Blanchard & H Baumann. (2002) Origin licensing and programmed cell death: a hypothesis. Cell Death & Differentiation 9:9, pages 870-872.
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Ming Lei, Irene H. Cheng, Louis A. Roberts, Michael A. McAlear & Bik K. Tye. (2002) Two mcm3 Mutations Affect Different Steps in the Initiation of DNA Replication. Journal of Biological Chemistry 277:34, pages 30824-30831.
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Frederic Blanchard, Michael E. RusiniakKaruna SharmaXiaolei SunIvan Todorov, M. Mar Castellano, Crisanto Gutierrez, Heinz Baumann & William C. Burhans. (2002) Targeted Destruction of DNA Replication Protein Cdc6 by Cell Death Pathways in Mammals and Yeast. Molecular Biology of the Cell 13:5, pages 1536-1549.
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Keiichi Watanabe, Jun Morishita, Keiko Umezu, Katsuhiko Shirahige & Hisaji Maki. (2002) Involvement of RAD9 -Dependent Damage Checkpoint Control in Arrest of Cell Cycle, Induction of Cell Death, and Chromosome Instability Caused by Defects in Origin Recognition Complex in Saccharomyces cerevisiae . Eukaryotic Cell 1:2, pages 200-212.
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Karim LabibStephen E. Kearsey & John F.X. Diffley. (2001) MCM2–7 Proteins Are Essential Components of Prereplicative Complexes that Accumulate Cooperatively in the Nucleus during G1-phase and Are Required to Establish, But Not Maintain, the S-phase Checkpoint. Molecular Biology of the Cell 12:11, pages 3658-3667.
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Michael Weinreich, Chun Liang, Hsu-Hsin Chen & Bruce Stillman. (2001) Binding of cyclin-dependent kinases to ORC and Cdc6p regulates the chromosome replication cycle. Proceedings of the National Academy of Sciences 98:20, pages 11211-11217.
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Sandra E. Encalada, Paula R. Martin, Jennifer B. Phillips, Rebecca Lyczak, Danielle R. Hamill, Kathryn A. Swan & Bruce Bowerman. (2000) DNA Replication Defects Delay Cell Division and Disrupt Cell Polarity in Early Caenorhabditis elegans Embryos. Developmental Biology 228:2, pages 225-238.
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Pedro Jares, Anne Donaldson & J Julian Blow. (2000) The Cdc7/Dbf4 protein kinase: target of the S phase checkpoint?. EMBO reports 1:4, pages 319-322.
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R.A. Sclafani. (2000) Cdc7p-Dbf4p becomes famous in the cell cycle. Journal of Cell Science 113:12, pages 2111-2117.
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Joan Kiely, S B Haase, Paul Russell & Janet Leatherwood. (2000) Functions of Fission Yeast Orp2 in DNA Replication and Checkpoint Control. Genetics 154:2, pages 599-607.
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S.W. James, K.A. Bullock, S.E. Gygax, B.A. Kraynack, R.A. Matura, J.A. MacLeod, K.K. McNeal, K.A. Prasauckas, P.C. Scacheri, H.L. Shenefiel, H.M. Tobin & S.D. Wade. (1999) nimO, an Aspergillus gene related to budding yeast Dbf4, is required for DNA synthesis and mitotic checkpoint control. Journal of Cell Science 112:9, pages 1313-1324.
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Robert V. Skibbens & Philip Hieter. (1998) KINETOCHORES AND THE CHECKPOINT MECHANISM THAT MONITORS FOR DEFECTS IN THE CHROMOSOME SEGREGATION MACHINERY. Annual Review of Genetics 32:1, pages 307-337.
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Rajiv Dua, Daniel L. Levy & Judith L. Campbell. (1998) Role of the Putative Zinc Finger Domain of Saccharomyces cerevisiae DNA Polymerase ε in DNA Replication and the S/M Checkpoint Pathway. Journal of Biological Chemistry 273:45, pages 30046-30055.
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David Stuart & Curt Wittenberg. (1998) CLB5 and CLB6 are required for premeiotic DNA replication and activation of the meiotic S/M checkpoint . Genes & Development 12:17, pages 2698-2710.
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Ted Weinert. (1998) DNA damage checkpoints update: getting molecular. Current Opinion in Genetics & Development 8:2, pages 185-193.
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Kevin G. Hardwick. (1998) The spindle checkpoint. Trends in Genetics 14:1, pages 1-4.
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M. D. Mendenhall. 1998. Cyclin Dependent Kinase (CDK) Inhibitors. Cyclin Dependent Kinase (CDK) Inhibitors 1 24 .
Anindya DuttaStephen P. Bell. (1997) INITIATION OF DNA REPLICATION IN EUKARYOTIC CELLS. Annual Review of Cell and Developmental Biology 13:1, pages 293-332.
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Tomoyuki Tanaka, Dunja Knapp & Kim Nasmyth. (1997) Loading of an Mcm Protein onto DNA Replication Origins Is Regulated by Cdc6p and CDKs. Cell 90:4, pages 649-660.
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Raymond J Deshaies. (1997) Phosphorylation and proteolysis: partners in the regulation of cell division in budding yeast. Current Opinion in Genetics & Development 7:1, pages 7-16.
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Simonetta Piatti. 1997. Progress in Cell Cycle Research. Progress in Cell Cycle Research 143 156 .
Adam D Rudner & Andrew W Murray. (1996) The spindle assembly checkpoint. Current Opinion in Cell Biology 8:6, pages 773-780.
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Stephen E Kearsey, Karim Labib & Domenico Maiorano. (1996) Cell cycle control of eukaryotic DNA replication. Current Opinion in Genetics & Development 6:2, pages 208-214.
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David Moore & Lilyann Novak Frazer. (1996) One stop mycology. Mycological Research 100:4, pages 505-512.
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