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Molecular and Cellular Biology Volume 15, 1995 - Issue 5
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Research Article

The Unique Amino-Terminal Domain of p56lck Regulates Interactions with Tyrosine Protein Phosphatases in T Lymphocytes

François G. Gervais1 McGill Cancer Centre, McGill University, Montréal, CanadaH3G 1Y6;2 Departments of Biochemistry, McGill University, Montréal, CanadaH3G 1Y6
&
André Veillette1 McGill Cancer Centre, McGill University, Montréal, CanadaH3G 1Y6;2 Departments of Biochemistry, McGill University, Montréal, CanadaH3G 1Y6;3 Medicine, McGill University, Montréal, CanadaH3G 1Y6;4 Oncology, McGill University, Montréal, CanadaH3G 1Y6;5 Departments of Medicine, Montreal General Hospital, Montréal, CanadaH3G 1A4;6 Oncology, Montreal General Hospital, Montréal, CanadaH3G 1A4Correspondence[email protected]
Pages 2393-2401 | Received 30 Dec 1994, Accepted 06 Feb 1995, Published online: 30 Mar 2023

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Jean-François Cloutier, Lionel M. L. Chow & André Veillette. (1995) Requirement of the SH3 and SH2 Domains for the Inhibitory Function of Tyrosine Protein Kinase p50 in T Lymphocytes. Molecular and Cellular Biology 15:11, pages 5937-5944.
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Articles from other publishers (29)

Yuanqing Ma, Elvis Pandzic, Philip R. Nicovich, Yui Yamamoto, Joanna Kwiatek, Sophie V. Pageon, Aleš Benda, Jérémie Rossy & Katharina Gaus. (2017) An intermolecular FRET sensor detects the dynamics of T cell receptor clustering. Nature Communications 8:1.
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Yuanqing Ma, Aleš Benda, Philip R. Nicovich & Katharina Gaus. (2016) Measuring membrane association and protein diffusion within membranes with supercritical angle fluorescence microscopy. Biomedical Optics Express 7:4, pages 1561.
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Julie Zikherman, Ramya Parameswaran, Michelle Hermiston & Arthur Weiss. (2013) The Structural Wedge Domain of the Receptor-like Tyrosine Phosphatase CD45 Enforces B Cell Tolerance by Regulating Substrate Specificity. The Journal of Immunology 190:6, pages 2527-2535.
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Robert J. SalmondAndrew Filby, Niina Pirinen, Anthony I. Magee & Rose Zamoyska. (2011) Mislocalization of Lck impairs thymocyte differentiation and can promote development of thymomas. Blood 117:1, pages 108-117.
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Graham Pitcher, Lorraine Kalia, Xue Jun Liu, Michael Salter & Yina Dong. 2008. Biology of the NMDA Receptor. Biology of the NMDA Receptor 123 148 .
Wasim A. Dar & Stuart J. Knechtle. (2007) CXCR3-mediated T-cell chemotaxis involves ZAP-70 and is regulated by signalling through the T-cell receptor. Immunology 120:4, pages 467-485.
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Rustom Falahati & David Leitenberg. (2007) Changes in the Role of the CD45 Protein Tyrosine Phosphatase in Regulating Lck Tyrosine Phosphorylation during Thymic Development. The Journal of Immunology 178:4, pages 2056-2064.
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Tahir M. Razzaq, Patricia Ozegbe, Elizabeth C. Jury, Phupinder Sembi, Nathan M. Blackwell & Panagiotis S. Kabouridis. (2004) Regulation of T-cell receptor signalling by membrane microdomains. Immunology 113:4, pages 413-426.
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Francois Spertini, Veronique Perret-Menoud, Nathalie Barbier, Talal Chatila, Catherine Barbey & Blaise Corthesy. (2004) Epitope-specific crosslinking of CD45 down-regulates membrane-associated tyrosine phosphatase activity and triggers early signalling events in human activated T cells. Immunology 113:4, pages 441-452.
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Lorraine V Kalia, Jeffrey R Gingrich & Michael W Salter. (2004) Src in synaptic transmission and plasticity. Oncogene 23:48, pages 8007-8016.
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Frederic Luciano, Magali Herrant, Arnaud Jacquel, Jean‐Ehrland Ricci & Patrick Auberger. (2003) The P54‐cleaved form of the tyrosine kinase Lyn generated by caspases during BCR‐induced cell death in B lymphoma acts as a negative regulator of apoptosis. The FASEB Journal 17:6, pages 711-713.
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Frederic Luciano, Jean-Ehrland Ricci & Patrick Auberger. (2001) Cleavage of Fyn and Lyn in their N-terminal unique regions during induction of apoptosis: a new mechanism for Src kinase regulation. Oncogene 20:36, pages 4935-4941.
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John G. Hoey, Justin Summy & Daniel C. Flynn. (2000) Chimeric constructs containing the SH4/Unique domains of cYes can restrict the ability of Src527F to upregulate heme oxygenase-1 expression efficiently. Cellular Signalling 12:9-10, pages 691-701.
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Young Bong Choi, Chan Ki Kim & Yungdae Yun. (1999) Lad, an Adapter Protein Interacting with the SH2 Domain of p56 lck , Is Required for T Cell Activation  . The Journal of Immunology 163:10, pages 5242-5249.
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Jonathan D Ashwell & Ugo D'Oro. (1999) CD45 and Src-family kinases: and now for something completely different. Immunology Today 20:9, pages 412-416.
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Bernadine L. Leung, Loralee Haughn, André Veillette, Robert G. Hawley, Robert Rottapel & Michael Julius. (1999) TCRαβ-Independent CD28 Signaling and Costimulation Require Non-CD4-Associated Lck. The Journal of Immunology 163:3, pages 1334-1341.
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André Veillette, David Soussou, Sylvain Latour, Dominique Davidson & François G. Gervais. (1999) Interactions of CD45-associated Protein with the Antigen Receptor Signaling Machinery in T-lymphocytes. Journal of Biological Chemistry 274:20, pages 14392-14399.
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Jean-François Cloutier & André Veillette. (1999) Cooperative Inhibition of  T-Cell Antigen Receptor Signaling by a Complex between a Kinase and a Phosphatase. Journal of Experimental Medicine 189:1, pages 111-121.
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Satoshi Motoya, Koichi Kitamura, Akio Matsuda, Abby L. Maizel, Hiroyuki Yamamoto & Akiko Takeda. (1999) Interaction between CD45-AP and Protein-tyrosine Kinases Involved in T Cell Receptor Signaling. Journal of Biological Chemistry 274:3, pages 1407-1414.
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Ralph S. Lin, Carlos Rodriguez, André Veillette & Harvey F. Lodish. (1998) Zinc Is Essential for Binding of p56 to CD4 and CD8α. Journal of Biological Chemistry 273:49, pages 32878-32882.
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Abdellah Elhabazi, Valérie Lang, Cécile Hérold, Gordon J. Freeman, Armand Bensussan, Laurence Boumsell & Georges Bismuth. (1997) The Human Semaphorin-like Leukocyte Cell Surface Molecule CD100 Associates with a Serine Kinase Activity. Journal of Biological Chemistry 272:38, pages 23515-23520.
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Benjamin G Neel. (1997) Role of phosphatases in lymphocyte activation. Current Opinion in Immunology 9:3, pages 405-420.
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François G. Gervais & André Veillette. (1997) Reconstitution of Interactions between Protein-tyrosine Phosphatase CD45 and Tyrosine-protein Kinase p56 in Nonlymphoid Cells. Journal of Biological Chemistry 272:19, pages 12754-12761.
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Jose Alberola-IlaSatoshi TakakiJames D. KernerRoger M. Perlmutter. (1997) DIFFERENTIAL SIGNALING BY LYMPHOCYTE ANTIGEN RECEPTORS. Annual Review of Immunology 15:1, pages 125-154.
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Tatiana Ulyanova, Julie Blasioli & Matthew L. Thomas. (1997) Regulation of cell signaling by the protein tyrosine phosphatases, CD45 and SHP-1. Immunologic Research 16:1, pages 101-113.
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Pascale Duplay, Andrés Alcover, Christine Fargeas, Rafick P. Sékaly & Philip E. Branton. (1996) An Activated Epidermal Growth Factor Receptor/Lck Chimera Restores Early T Cell Receptor-mediated Calcium Response in a CD45-deficient T Cell Line. Journal of Biological Chemistry 271:30, pages 17896-17902.
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Megan T. Brown & Jonathan A. Cooper. (1996) Regulation, substrates and functions of src. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1287:2-3, pages 121-149.
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David H.W. Ng, Julian D. Watts, Ruedi Aebersold & Pauline Johnson. (1996) Demonstration of a Direct Interaction between p56 and the Cytoplasmic Domain of CD45 in Vitro. Journal of Biological Chemistry 271:3, pages 1295-1300.
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Ellen D. Cahir McFarland & Matthew L. Thomas. (1995) CD45 Protein-tyrosine Phosphatase Associates with the WW Domain-containing Protein, CD45AP, through the Transmembrane Region. Journal of Biological Chemistry 270:47, pages 28103-28107.
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