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Research Article

DNA-Binding and Transactivation Properties of Pax-6: Three Amino Acids in the Paired Domain Are Responsible for the Different Sequence Recognition of Pax-6 and BSAP (Pax-5)

Thomas CzernyResearch Institute of Molecular Pathology, A-1030Vienna, Austria
&
Meinrad BusslingerResearch Institute of Molecular Pathology, A-1030Vienna, Austria
Pages 2858-2871 | Received 28 Sep 1994, Accepted 17 Feb 1995, Published online: 30 Mar 2023

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Gregory R. Dressler. (2009) The specification and maintenance of renal cell types by epigenetic factors. Organogenesis 5:2, pages 73-82.
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Kyle J. Vogan, D. Alan Underhill & Philippe Gros. (1996) An Alternative Splicing Event in the Pax-3 Paired Domain Identifies the Linker Region as a Key Determinant of Paired Domain DNA-Binding Activity. Molecular and Cellular Biology 16:12, pages 6677-6686.
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Dagmar SchinnerlKlaus FortscheggerMaximilian KauerJoão R. M. Marchante, Reinhard Kofler, Monique L. Den Boer & Sabine Strehl. (2015) The role of the Janus-faced transcription factor PAX5-JAK2 in acute lymphoblastic leukemia. Blood 125:8, pages 1282-1291.
Crossref
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Crossref
Alessandro Minelli. 2015. Evolutionary Developmental Biology of Invertebrates 1. Evolutionary Developmental Biology of Invertebrates 1 1 23 .
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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S. H. Cross, L. McKie, K. West, E. L. Coghill, J. Favor, S. Bhattacharya, S. D. M. Brown & I. J. Jackson. (2010) The Opdc missense mutation of Pax2 has a milder than loss-of-function phenotype. Human Molecular Genetics 20:2, pages 223-234.
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Akihito Omori, Koji Akasaka, Daisuke Kurokawa & Shonan Amemiya. (2011) Gene expression analysis of Six3, Pax6, and Otx in the early development of the stalked crinoid Metacrinus rotundus. Gene Expression Patterns 11:1-2, pages 48-56.
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Zipora Yablonka-Reuveni & Kenneth Day. 2011. Regenerating the Heart. Regenerating the Heart 173 200 .
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Crossref
Hiroshi Suga, Patrick Tschopp, Daria F. Graziussi, Michael Stierwald, Volker Schmid & Walter J. Gehring. (2010) Flexibly deployed Pax genes in eye development at the early evolution of animals demonstrated by studies on a hydrozoan jellyfish . Proceedings of the National Academy of Sciences 107:32, pages 14263-14268.
Crossref
April Hill, Werner Boll, Carolin Ries, Lisa Warner, Marisa Osswalt, Malcolm Hill & Markus Noll. (2010) Origin of Pax and Six gene families in sponges: Single PaxB and Six1/2 orthologs in Chalinula loosanoffi. Developmental Biology 343:1-2, pages 106-123.
Crossref
Shioh Ooka, Tomoko Katow, Shunsuke Yaguchi, Junko Yaguchi & Hideki Katow. (2010) Spatiotemporal expression pattern of an encephalopsin orthologue of the sea urchin Hemicentrotus pulcherrimus during early development, and its potential role in larval vertical migration. Development, Growth & Differentiation 52:2, pages 195-207.
Crossref
Yun Zhang, Yoichi Yamada, Mingming Fan, Saroja D. Bangaru, Bochao Lin & Jian Yang. (2010) The β Subunit of Voltage-gated Ca2+ Channels Interacts with and Regulates the Activity of a Novel Isoform of Pax6. Journal of Biological Chemistry 285:4, pages 2527-2536.
Crossref
Mark Charlton-Perkins & Tiffany A. Cook. 2010. Invertebrate and Vertebrate Eye Development. Invertebrate and Vertebrate Eye Development 129 173 .
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Bin Lu, Nina Wang, Jinhua Xiao, Yongyu Xu, Robert W Murphy & Dawei Huang. (2009) Expression and evolutionary divergence of the non-conventional olfactory receptor in four species of fig wasp associated with one species of fig. BMC Evolutionary Biology 9:1.
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Baubak Bajoghli, Mirana Ramialison, Narges Aghaallaei, Thomas Czerny & Joachim Wittbrodt. (2009) Identification of starmaker-like in medaka as a putative target gene of Pax2 in the otic vesicle . Developmental Dynamics 238:11, pages 2860-2866.
Crossref
Jason Clements, Korneel Hens, Srinivas Merugu, Beatriz Dichtl, H. Gert de Couet & Patrick Callaerts. (2009) Mutational analysis of the eyeless gene and phenotypic rescue reveal that an intact Eyeless protein is necessary for normal eye and brain development in Drosophila. Developmental Biology 334:2, pages 503-512.
Crossref
Bonnie M. Weasner, Brandon Weasner, Stephanie M. DeYoung, Scott D. Michaels & Justin P. Kumar. (2009) Transcriptional activities of the Pax6 gene eyeless regulate tissue specificity of ectopic eye formation in Drosophila. Developmental Biology 334:2, pages 492-502.
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Y. Wang, J. C. Groppe, J. Wu, T. Ogawa, G. Mues, R. N. D'Souza & H. Kapadia. (2009) Pathogenic mechanisms of tooth agenesis linked to paired domain mutations in human PAX9. Human Molecular Genetics 18:15, pages 2863-2874.
Crossref
Annie Mercier & Jean-François Hamel. 2009. Endogenous and Exogenous Control of Gametogenesis and Spawning in Echinoderms. Endogenous and Exogenous Control of Gametogenesis and Spawning in Echinoderms 237 291 .
Annie Mercier & Jean-François Hamel. 2009. Endogenous and Exogenous Control of Gametogenesis and Spawning in Echinoderms. Endogenous and Exogenous Control of Gametogenesis and Spawning in Echinoderms 169 194 .
John W. Cave & Harriet Baker. 2009. Development and Engineering of Dopamine Neurons. Development and Engineering of Dopamine Neurons 15 35 .
Luitfried von Salvini-Plawen. (2008) Photoreception and the Polyphyletic Evolution of Photoreceptors (with Special Reference to Mollusca)*. American Malacological Bulletin 26:1-2, pages 83-100.
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David C. Blackburn, Kevin W. Conley, David C. Plachetzki, Karen Kempler, Barbara-Anne Battelle & Nadean L. Brown. (2008) Isolation and expression of Pax6 and atonal homologues in the American horseshoe crab, Limulus polyphemus . Developmental Dynamics 237:8, pages 2209-2219.
Crossref
Noriko Osumi, Hiroshi Shinohara, Keiko Numayama-Tsuruta & Motoko Maekawa. (2008) Concise Review: Pax6 Transcription Factor Contributes to both Embryonic and Adult Neurogenesis as a Multifunctional Regulator. Stem Cells 26:7, pages 1663-1672.
Crossref
Jack Favor, Christian Johannes Gloeckner, Angelika Neuhäuser-Klaus, Walter Pretsch, Rodica Sandulache, Simon Saule & Irmgard Zaus. (2008) Relationship of Pax6 Activity Levels to the Extent of Eye Development in the Mouse, Mus musculus . Genetics 179:3, pages 1345-1355.
Crossref
Stephen Short & Linda Z. Holland. (2008) The Evolution of Alternative Splicing in the Pax Family: The View from the Basal Chordate Amphioxus. Journal of Molecular Evolution 66:6, pages 605-620.
Crossref
Grazia Fazio, Chiara Palmi, Antonius Rolink, Andrea Biondi & Giovanni Cazzaniga. (2008) PAX5/TEL Acts as a Transcriptional Repressor Causing Down-modulation of CD19, Enhances Migration to CXCL12, and Confers Survival Advantage in pre-BI Cells. Cancer Research 68:1, pages 181-189.
Crossref
Margaret BuckinghamFrédéric Relaix. (2007) The Role of Pax Genes in the Development of Tissues and Organs: Pax3 and Pax7 Regulate Muscle Progenitor Cell Functions . Annual Review of Cell and Developmental Biology 23:1, pages 645-673.
Crossref
Ying Chen, Marija Kundakovic, Roberto C. Agis-Balboa, Graziano Pinna & Dennis R. Grayson. (2007) Induction of the reelin promoter by retinoic acid is mediated by Sp1. Journal of Neurochemistry 103:2, pages 650-665.
Crossref
Masashi Inoue, Yusuke Kamachi, Hideyuki Matsunami, Katsumi Imada, Masanori Uchikawa & Hisato Kondoh. (2007) PAX6 and SOX2-dependent regulation of the Sox2 enhancer N-3 involved in embryonic visual system development. Genes to Cells 12:9, pages 1049-1061.
Crossref
Ian K. Quigley, Xuanhua Xie & Marty Shankland. (2007) Hau-Pax6A expression in the central nervous system of the leech embryo. Development Genes and Evolution 217:6, pages 459-468.
Crossref
Charles G. Mullighan, Salil Goorha, Ina Radtke, Christopher B. Miller, Elaine Coustan-Smith, James D. Dalton, Kevin Girtman, Susan Mathew, Jing Ma, Stanley B. Pounds, Xiaoping Su, Ching-Hon Pui, Mary V. Relling, William E. Evans, Sheila A. Shurtleff & James R. Downing. (2007) Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia. Nature 446:7137, pages 758-764.
Crossref
Charles W Walker, Tatsuya Unuma & Michael P Lesser. 2007. Edible Sea Urchins: Biology and Ecology. Edible Sea Urchins: Biology and Ecology 11 33 .
R.D. Burke, L.M. Angerer, M.R. Elphick, G.W. Humphrey, S. Yaguchi, T. Kiyama, S. Liang, X. Mu, C. Agca, W.H. Klein, B.P. Brandhorst, M. Rowe, K. Wilson, A.M. Churcher, J.S. Taylor, N. Chen, G. Murray, D. Wang, D. Mellott, R. Olinski, F. Hallböök & M.C. Thorndyke. (2006) A genomic view of the sea urchin nervous system. Developmental Biology 300:1, pages 434-460.
Crossref
Steven A. Benner, Slim O. Sassi & Eric A. Gaucher. 2006. Advances in Enzymology. Advances in Enzymology 1 132 .
Inka Pawlitzky, Christina V. Angeles, Andrea M. Siegel, Michelle L. Stanton, Roy Riblet & Peter H. Brodeur. (2006) Identification of a Candidate Regulatory Element within the 5′ Flanking Region of the Mouse Igh Locus Defined by Pro-B Cell-Specific Hypersensitivity Associated with Binding of PU.1, Pax5, and E2A . The Journal of Immunology 176:11, pages 6839-6851.
Crossref
Zhixin Zhang, Celia R Espinoza, Zhihong Yu, Robert Stephan, Ti He, G Stuart Williams, Peter D Burrows, James Hagman, Ann J Feeney & Max D Cooper. (2006) Transcription factor Pax5 (BSAP) transactivates the RAG-mediated VH-to-DJH rearrangement of immunoglobulin genes. Nature Immunology 7:6, pages 616-624.
Crossref
Ying Yang, Tomáš Stopka, Nady Golestaneh, Yan Wang, Kongming Wu, Anping Li, Bharesh K Chauhan, Chun Y Gao, Květa Cveklová, Melinda K Duncan, Richard G Pestell, Ana B Chepelinsky, Arthur I Skoultchi & Aleš Cvekl. (2006) Regulation of αA-crystallin via Pax6, c-Maf, CREB and a broad domain of lens-specific chromatin. The EMBO Journal 25:10, pages 2107-2118.
Crossref
Hiromi Tagoh, Richard Ingram, Nicola Wilson, Giorgia Salvagiotto, Alan J Warren, Deborah Clarke, Meinrad Busslinger & Constanze Bonifer. (2006) The mechanism of repression of the myeloid-specific c-fms gene by Pax5 during B lineage restriction. The EMBO Journal 25:5, pages 1070-1080.
Crossref
Zbynek Kozmik. (2005) Pax genes in eye development and evolution. Current Opinion in Genetics & Development 15:4, pages 430-438.
Crossref
Jih-Guang Yao & Y Henry Sun. (2005) Eyg and Ey Pax proteins act by distinct transcriptional mechanisms in Drosophila development. The EMBO Journal 24:14, pages 2602-2612.
Crossref
Maxime Bouchard, David Grote, Sarah E. Craven, Qiong Sun, Peter Steinlein & Meinrad Busslinger. (2005) Identification of Pax2-regulated genes by expression profiling of the mid-hindbrain organizer region. Development 132:11, pages 2633-2643.
Crossref
Jorge Blanco, Franck Girard, Yusuke Kamachi, Hisato Kondoh & Walter J. Gehring. (2005) Functional analysis of the chicken δ1-crystallin enhancer activity in Drosophila reveals remarkable evolutionary conservation between chicken and fly . Development 132:8, pages 1895-1905.
Crossref
Hediye Nese Cinar & Andrew D Chisholm. (2004) Genetic Analysis of the Caenorhabditis elegans pax-6 Locus. Genetics 168:3, pages 1307-1322.
Crossref
Gilles A. Robichaud, Michel Nardini, Mark Laflamme, Miroslava Cuperlovic-Culf & Rodney J. Ouellette. (2004) Human Pax-5 C-terminal Isoforms Possess Distinct Transactivation Properties and Are Differentially Modulated in Normal and Malignant B Cells. Journal of Biological Chemistry 279:48, pages 49956-49963.
Crossref
. 2010. Development of the Ocular Lens. Development of the Ocular Lens.
Daisuke Kurokawa, Hiroshi Kiyonari, Rika Nakayama, Chiharu Kimura-Yoshida, Isao Matsuo & Shinichi Aizawa. (2004) Regulation of Otx2 expression and its functions in mouse forebrain and midbrain . Development 131:14, pages 3319-3331.
Crossref
Ale? Cvekl & Ernst R. Tamm. (2004) Anterior eye development and ocular mesenchyme: new insights from mouse models and human diseases. BioEssays 26:4, pages 374-386.
Crossref
Ylva Linderson, Dirk Eberhard, Stephen Malin, Annica Johansson, Meinrad Busslinger & Sven Pettersson. (2004) Corecruitment of the Grg4 repressor by PU.1 is critical for Pax5‐mediated repression of B‐cell‐specific genes. EMBO reports 5:3, pages 291-296.
Crossref
John K. Mensah, Takuya Ogawa, Hitesh Kapadia, Adriana C. Cavender & Rena N. D'Souza. (2004) Functional Analysis of a Mutation in PAX9 Associated with Familial Tooth Agenesis in Humans. Journal of Biological Chemistry 279:7, pages 5924-5933.
Crossref
Dirk A Kleinjan, Anne Seawright, Andrew J Childs & Veronica van Heyningen. (2004) Conserved elements in Pax6 intron 7 involved in (auto)regulation and alternative transcription. Developmental Biology 265:2, pages 462-477.
Crossref
Zbynek Kozmik, Michael Daube, Erich Frei, Barbara Norman, Lidia Kos, Larry J. Dishaw, Markus Noll & Joram Piatigorsky. (2003) Role of Pax Genes in Eye Evolution. Developmental Cell 5:5, pages 773-785.
Crossref
Karin Nordström, Ingo Scholten, Johanna Nordström, Dan Larhammar & David Miller. (2003) Mutational analysis of the Acropora millepora PaxD paired domain highlights the importance of the linker region for DNA binding. Gene 320, pages 81-87.
Crossref
Serge Plaza, Danielle M. De Jong, Walter J. Gehring & David J. Miller. (2003) DNA-binding characteristics of cnidarian Pax-C and Pax-B proteins in vivo and in vitro: No simple relationship with the Pax-6 and Pax-2/5/8 classes. Journal of Experimental Zoology 299B:1, pages 26-35.
Crossref
Matthew J. Harley & Joel F. Schildbach. (2003) Swapping single-stranded DNA sequence specificities of relaxases from conjugative plasmids F and R100. Proceedings of the National Academy of Sciences 100:20, pages 11243-11248.
Crossref
Raffaella Scardigli, Nicole Bäumer, Peter Gruss, François Guillemot & Isabelle Le Roux. (2003) Direct and concentration-dependent regulation of the proneural gene Neurogenin2 by Pax6 . Development 130:14, pages 3269-3281.
Crossref
Shin-ichi Aota, Noboru Nakajima, Ruriko Sakamoto, Sonoe Watanabe, Nobuhiro Ibaraki & Kenji Okazaki. (2003) Pax6 autoregulation mediated by direct interaction of Pax6 protein with the head surface ectoderm-specific enhancer of the mouse Pax6 gene. Developmental Biology 257:1, pages 1-13.
Crossref
B Hartmann, P.N Lee, Y.Y Kang, S Tomarev, H.G de Couet & P Callaerts. (2003) Pax6 in the sepiolid squid Euprymna scolopes: evidence for a role in eye, sensory organ and brain development. Mechanisms of Development 120:2, pages 177-183.
Crossref
Rajnikant Mishra, Ivan P. Gorlov, Lian Y. Chao, Sanjaya Singh & Grady F. Saunders. (2002) PAX6, Paired Domain Influences Sequence Recognition by the Homeodomain. Journal of Biological Chemistry 277:51, pages 49488-49494.
Crossref
Bharesh K. Chauhan, Nathan A. Reed, Ying Yang, Lukáš Čermák, Lixing Reneker, Melinda K. Duncan & Aleš Cvekl. (2002) A comparative cDNA microarray analysis reveals a spectrum of genes regulated by Pax6 in mouse lens. Genes to Cells 7:12, pages 1267-1283.
Crossref
Michael Schebesta, Peter L. Pfeffer & Meinrad Busslinger. (2002) Control of Pre-BCR Signaling by Pax5-Dependent Activation of the BLNK Gene. Immunity 17:4, pages 473-485.
Crossref
Hongmin Sun, Srinivas Merugu, Xun Gu, Yuan Yuan Kang, Douglas P. Dickinson, Patrick Callaerts & Wen-Hsiung Li. (2002) Identification of Essential Amino Acid Changes in Paired Domain Evolution Using a Novel Combination of Evolutionary Analysis and In Vitro and In Vivo Studies. Molecular Biology and Evolution 19:9, pages 1490-1500.
Crossref
Shyng-Shiou F Yuan, Yao-Tsung Yeh & Eva Y.-H.P Lee. (2002) Pax-2 interacts with RB and reverses its repression on the promoter of Rig-1, a Robo member. Biochemical and Biophysical Research Communications 296:4, pages 1019-1025.
Crossref
Gustavo A. Miranda, Maria Villalvazo, Zoran Galic, Jackelyn Alva, Roxanna Abrines, Yvette Yates, Cory J. Evans & Renato J. Aguilera. (2002) Combinatorial regulation of the murine RAG-2 promoter by Sp1 and distinct lymphocyte-specific transcription factors. Molecular Immunology 38:15, pages 1151-1159.
Crossref
Sylvia Vlcek, Barbara Korbei & Roland Foisner. (2002) Distinct Functions of the Unique C Terminus of LAP2α in Cell Proliferation and Nuclear Assembly. Journal of Biological Chemistry 277:21, pages 18898-18907.
Crossref
David Pineda, Leonardo Rossi, Renata Batistoni, Alessandra Salvetti, Maria Marsal, Vittorio Gremigni, Alessandra Falleni, Javier Gonzalez-Linares, Paolo Deri & Emili Saló. (2002) The genetic network of prototypic planarian eye regeneration is Pax6 independent. Development 129:6, pages 1423-1434.
Crossref
Jarmila Králová, Thomas Czerny, Hana Španielová, Veronika Ratajová & Zbynek Kozmik. (2002) Complex regulatory element within the γE- and γF-crystallin enhancers mediates Pax6 regulation and is required for induction by retinoic acid. Gene 286:2, pages 271-282.
Crossref
Claudio Punzo, Makiko Seimiya, Susanne Flister, Walter J. Gehring & Serge Plaza. (2002) Differential interactions of eyeless and twin of eyeless with the sine oculis enhancer . Development 129:3, pages 625-634.
Crossref
Peter L. Pfeffer, Bernhard Payer, Gerlinde Reim, Marina Pasca di Magliano & Meinrad Busslinger. (2002) The activation and maintenance of Pax2 expression at the mid-hindbrain boundary is controlled by separate enhancers . Development 129:2, pages 307-318.
Crossref
Eleonora Carosa, Zbynek Kozmik, J. Edward Rall & Joram Piatigorsky. (2002) Structure and Expression of the Scallop Ω-Crystallin Gene. Journal of Biological Chemistry 277:1, pages 656-664.
Crossref
Jana Krešlová, Linda Z Holland, Michael Schubert, Carola Burgtorf, Vladimı́r Beneš & Zbynek Kozmik. (2002) Functional equivalency of amphioxus and vertebrate Pax258 transcription factors suggests that the activation of mid-hindbrain specific genes in vertebrates occurs via the recruitment of Pax regulatory elements. Gene 282:1-2, pages 143-150.
Crossref
Peter W. Atkinson & Anthony A. James. 2002. 49 88e .
Jack Favor, Heiko Peters, Thomas Hermann, Wolfgang Schmahl, Bimal Chatterjee, Angelika Neuhäuser-Klaus & Rodica Sandulache. (2001) Molecular Characterization of Pax62Neu Through Pax610Neu : An Extension of the Pax6 Allelic Series and the Identification of Two Possible Hypomorph Alleles in the Mouse Mus musculus . Genetics 159:4, pages 1689-1700.
Crossref
Colin W Garvie, James Hagman & Cynthia Wolberger. (2001) Structural Studies of Ets-1/Pax5 Complex Formation on DNA. Molecular Cell 8:6, pages 1267-1276.
Crossref
H. Eric Xu, Millard H. Lambert, Valerie G. Montana, Kelli D. Plunket, Linda B. Moore, Jon L. Collins, Jeffery A. Oplinger, Steven A. Kliewer, Robert T. GampeJr.Jr., David D. McKee, John T. Moore & Timothy M. Willson. (2001) Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors. Proceedings of the National Academy of Sciences 98:24, pages 13919-13924.
Crossref
Detlev Arendt & Joachim Wittbrodt. (2001) Reconstructing the eyes of Urbilateria. Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences 356:1414, pages 1545-1563.
Crossref
Hongmin Sun, Douglas P. Dickinson, John Costello & Wen-Hsiung Li. (2001) Isolation of Cladonema Pax-B Genes and Studies of the DNA-Binding Properties of Cnidarian Pax Paired Domains. Molecular Biology and Evolution 18:10, pages 1905-1918.
Crossref
Renjie Jiao, Michael Daube, Hong Duan, Yu Zou, Erich Frei & Markus Noll. (2001) Headless flies generated by developmental pathway interference. Development 128:17, pages 3307-3319.
Crossref
Andrew D. Johnson, Daniel Fitzsimmons, James Hagman & Helen M. Chamberlin. (2001) EGL-38 Pax regulates the ovo -related gene lin-48 during Caenorhabditis elegans organ development . Development 128:15, pages 2857-2865.
Crossref
Lars Kammermeier & Heinrich Reichert. (2001) Common developmental genetic mechanisms for patterning invertebrate and vertebrate brains. Brain Research Bulletin 55:6, pages 675-682.
Crossref
Christine Dozier, Hiroshi Kagoshima, Gisela Niklaus, Giuseppe Cassata & Thomas R Bürglin. (2001) The Caenorhabditis elegans Six/sine oculis Class Homeobox Gene ceh-32 Is Required for Head Morphogenesis. Developmental Biology 236:2, pages 289-303.
Crossref
Oleg Lagutin, Changqi C. Zhu, Yasuhide Furuta, David H. Rowitch, Andrew P. McMahon & Guillermo Oliver. (2001) Six3 promotes the formation of ectopic optic vesicle-like structures in mouse embryos. Developmental Dynamics 221:3, pages 342-349.
Crossref
Yusuke Kamachi, Masanori Uchikawa, Aki Tanouchi, Ryohei Sekido & Hisato Kondoh. (2001) Pax6 and SOX2 form a co-DNA-binding partner complex that regulates initiation of lens development. Genes & Development 15:10, pages 1272-1286.
Crossref
Lars Kammermeier, Ronny Leemans, Frank Hirth, Susanne Flister, Urs Wenger, Uwe Walldorf, Walter J Gehring & Heinrich Reichert. (2001) Differential expression and function of the Drosophila Pax6 genes eyeless and twin of eyeless in embryonic central nervous system development. Mechanisms of Development 103:1-2, pages 71-78.
Crossref
Dmitri Papatsenko, Anna Nazina & Claude Desplan. (2001) A conserved regulatory element present in all Drosophila rhodopsin genes mediates Pax6 functions and participates in the fine-tuning of cell-specific expression. Mechanisms of Development 101:1-2, pages 143-153.
Crossref
P. Callaerts, S. Leng, J. Clements, C. Benassayag, D. Cribbs, Y.Y. Kang, U. Walldorf, K.-F. Fischbach & R. Strauss. (2001) Drosophila Pax-6/eyeless is essential for normal adult brain structure and function. Journal of Neurobiology 46:2, pages 73-88.
Crossref
Ingvild Mikkola, Jack-Ansgar Bruun, Turid Holm & Terje Johansen. (2001) Superactivation of Pax6-mediated Transactivation from Paired Domain-binding Sites by DNA-independent Recruitment of Different Homeodomain Proteins. Journal of Biological Chemistry 276:6, pages 4109-4118.
Crossref
C.W. Walker, T. Unuma, N.A. McGinn, L.M. Harrington & M.P. Lesser. 2001. Edible Sea Urchins: Biology and Ecology. Edible Sea Urchins: Biology and Ecology 5 26 .
Stuart B. Smith, Hirotaka Watada, David W. Scheel, Caroline Mrejen & Michael S. German. (2000) Autoregulation and Maturity Onset Diabetes of the Young Transcription Factors Control the Human PAX4 Promoter. Journal of Biological Chemistry 275:47, pages 36910-36919.
Crossref
D Alan Underhill. (2000) Genetic and biochemical diversity in the Pax gene family . Biochemistry and Cell Biology 78:5, pages 629-638.
Crossref
Beate Ritz-Laser, Anne Estreicher, Benoit Gauthier & Jacques Philippe. (2000) The Paired Homeodomain Transcription Factor Pax-2 Is Expressed in the Endocrine Pancreas and Transactivates the Glucagon Gene Promoter. Journal of Biological Chemistry 275:42, pages 32708-32715.
Crossref
M.K. Duncan, Z. Kozmik, K. Cveklova, J. Piatigorsky & A. Cvekl. (2000) Overexpression of PAX6(5a) in lens fiber cells results in cataract and upregulation of (alpha)5(beta)1 integrin expression. Journal of Cell Science 113:18, pages 3173-3185.
Crossref
Takaaki Hayashi, Jing Huang & Samir S. Deeb. (2000) RINX(VSX1), a Novel Homeobox Gene Expressed in the Inner Nuclear Layer of the Adult Retina. Genomics 67:2, pages 128-139.
Crossref
Sanjaya Singh, Christine M. Stellrecht, Hank K. Tang & Grady F. Saunders. (2000) Modulation of PAX6 Homeodomain Function by the Paired Domain. Journal of Biological Chemistry 275:23, pages 17306-17313.
Crossref
David J. Miller, David C. Hayward, John S. Reece-Hoyes, Ingo Scholten, Julian Catmull, Walter J. Gehring, Patrick Callaerts, Jill E. Larsen & Eldon E. Ball. (2000) Pax gene diversity in the basal cnidarian Acropora millepora (Cnidaria, Anthozoa): Implications for the evolution of the Pax gene family . Proceedings of the National Academy of Sciences 97:9, pages 4475-4480.
Crossref
Peter L. Pfeffer, Maxime Bouchard & Meinrad Busslinger. (2000) Pax2 and homeodomain proteins cooperatively regulate a 435 bp enhancer of the mouse Pax5 gene at the midbrain-hindbrain boundary . Development 127:5, pages 1017-1028.
Crossref
Yi-Hong Zhou, Jessica B. Zheng, Xun Gu, Wen-Hsuing Li & Grady F. Saunders. (2000) A novel Pax-6 binding site in rodent B1 repetitive elements: coevolution between developmental regulation and repeated elements?. Gene 245:2, pages 319-328.
Crossref
David J. Miller & Eldon E. Ball. (2000) The coral Acropora: What it can contribute to our knowledge of metazoan evolution and the evolution of developmental processes. BioEssays 22:3, pages 291-296.
Crossref
Peter Bialek, Chi-Tsung J. Chan & Siu-Pok Yee. (2000) Characterization of a Novel Insertional Mouse Mutation, kkt: A Closely Linked Modifier of Pax1. Developmental Biology 218:2, pages 354-366.
Crossref
J. Hagman, W. Wheat, D. Fitzsimmons, W. Hodsdon, J. Negri & F. Dizon. 2000. Signal Transduction and the Coordination of B Lymphocyte Development and Function I. Signal Transduction and the Coordination of B Lymphocyte Development and Function I 169 194 .
Bjarte Håvik, Erlend Ragnhildstveit, James B. Lorens, Kari Sælemyr, Oddbjørn Fauske, Lill K. Knudsen & Anders Fjose. (1999) A Novel Paired Domain DNA Recognition Motif Can Mediate Pax2 Repression of Gene Transcription. Biochemical and Biophysical Research Communications 266:2, pages 532-541.
Crossref
Kristine Seitz & Devin Leake. (1999) Utilizing the Web in the Classroom: Linking Student Scientists with Professional Data. The American Biology Teacher 61:8, pages 565-573.
Crossref
Jessica E. Treisman. (1999) A conserved blueprint for the eye?. BioEssays 21:10, pages 843-850.
Crossref
Hisato Kondoh. (1999) Transcription factors for lens development assessed in vivo. Current Opinion in Genetics & Development 9:3, pages 301-308.
Crossref
Gerald Stöber, Yana V Syagailo, Olga Okladnova, Gerd Jungkunz, Michael Knapp, Helmut Beckmann & Klaus-Peter Lesch. (1999) Functional PAX-6 gene-linked polymorphic region: potential association with paranoid schizophrenia. Biological Psychiatry 45:12, pages 1585-1591.
Crossref
Anna Kalousová, Vladimı́r Beneš, Jan Pačes, Václav Pačes & Zbyněk Kozmik. (1999) DNA Binding and Transactivating Properties of the Paired and Homeobox Protein Pax4. Biochemical and Biophysical Research Communications 259:3, pages 510-518.
Crossref
Teruyuki Niimi, Makiko Seimiya, Urs Kloter, Susanne Flister & Walter J. Gehring. (1999) Direct regulatory interaction of the eyeless protein with an eye-specific enhancer in the sine oculis gene during eye induction in Drosophila . Development 126:10, pages 2253-2260.
Crossref
Ingvild Mikkola, Jack-Ansgar Bruun, Geir Bjørkøy, Turid Holm & Terje Johansen. (1999) Phosphorylation of the Transactivation Domain of Pax6 by Extracellular Signal-regulated Kinase and p38 Mitogen-activated Protein Kinase. Journal of Biological Chemistry 274:21, pages 15115-15126.
Crossref
Thomas Czerny, Georg Halder, Urs Kloter, Abdallah Souabni, Walter J Gehring & Meinrad Busslinger. (1999) twin of eyeless, a Second Pax-6 Gene of Drosophila, Acts Upstream of eyeless in the Control of Eye Development. Molecular Cell 3:3, pages 297-307.
Crossref
P. Callaerts, A. M. Munoz-Marmol, S. Glardon, E. Castillo, H. Sun, W.-H. Li, W. J. Gehring & E. Salo. (1999) Isolation and expression of a Pax-6 gene in the regenerating and intact Planarian Dugesia(G)tigrina . Proceedings of the National Academy of Sciences 96:2, pages 558-563.
Crossref
Sanjaya Singh & Grady F. Saunders. (1998) A Method for Obtaining Reporter Gene Activity and Nuclear Extracts Simultaneously from Transiently Transfected Cells. Analytical Biochemistry 265:1, pages 185-187.
Crossref
Susie Jun, Robert V. Wallen, Anne Goriely, Bill Kalionis & Claude Desplan. (1998) Lune/eye gone, a Pax-like protein, uses a partial paired domain and a homeodomain for DNA recognition. Proceedings of the National Academy of Sciences 95:23, pages 13720-13725.
Crossref
Olga Okladnova, Yana V. Syagailo, Rainald Mössner, Peter Riederer & Klaus-Peter Lesch. (1998) Regulation of PAX-6 gene transcription: alternate promoter usage in human brain. Molecular Brain Research 60:2, pages 177-192.
Crossref
Gang Qiu & Janet Stavnezer. (1998) Overexpression of BSAP/Pax-5 Inhibits Switching to IgA and Enhances Switching to IgE in the I.29μ B Cell Line. The Journal of Immunology 161:6, pages 2906-2918.
Crossref
Svanhild Nornes, Michael Clarkson, Ingvild Mikkola, Marit Pedersen, Anne Bardsley, Juan Pedro Martinez, Stefan Krauss & Terje Johansen. (1998) Zebrafish contains two Pax6 genes involved in eye development1The sequence reported in this paper has been deposited in the GenBank data base (accession no. AF061252).1. Mechanisms of Development 77:2, pages 185-196.
Crossref
Sanjaya Singh, Hank Kejun Tang, Jing-Yu Lee & Grady F. Saunders. (1998) Truncation Mutations in the Transactivation Region of PAX6 Result in Dominant-Negative Mutants. Journal of Biological Chemistry 273:34, pages 21531-21541.
Crossref
Sacha Glardon, Linda Z. Holland, Walter J. Gehring & Nicholas D. Holland. (1998) Isolation and developmental expression of the amphioxus Pax-6 gene (AmphiPax-6 ): insights into eye and photoreceptor evolution . Development 125:14, pages 2701-2710.
Crossref
Yoshiharu Tokuyama, Kazuo Yagui, Ken-ichi Sakurai, Naotake Hashimoto, Yasushi Saito & Azuma Kanatsuka. (1998) Molecular Cloning of Rat Pax4: Identification of Four Isoforms in Rat Insulinoma Cells. Biochemical and Biophysical Research Communications 248:1, pages 153-156.
Crossref
Hank Kejun Tang, Sanjaya Singh & Grady F. Saunders. (1998) Dissection of the Transactivation Function of the Transcription Factor Encoded by the Eye Developmental Gene PAX6. Journal of Biological Chemistry 273:13, pages 7210-7221.
Crossref
Meinrad Busslinger & Stephen L. Nutt. 1998. Molecular Biology of B-Cell and T-Cell Development. Molecular Biology of B-Cell and T-Cell Development 83 110 .
Matthias T. F. Wolf, B Lorenz, A Winterpacht, M Drechsler, V Schumacher, B Royer-Pokora, A Blankenagel, B Zabel & G Wildhardt. (1998) Ten novel mutations found in aniridia. Human Mutation 12:5, pages 304-313.
Crossref
Jane Prosser & Veronica van Heyningen. (1998) PAX6 mutations reviewed. Human Mutation 11:2, pages 93-108.
Crossref
Stephen L. Nutt, Claire Thévenin & Meinrad Busslinger. (1997) Essential Functions of Pax-5 (BSAP) in pro-B Cell Development. Immunobiology 198:1-3, pages 227-235.
Crossref
Thomas Czerny, Maxime Bouchard, Zbynek Kozmik & Meinrad Busslinger. (1997) The characterization of novel Pax genes of the sea urchin and Drosophila reveal an ancient evolutionary origin of the Pax2/5/8 subfamily. Mechanisms of Development 67:2, pages 179-192.
Crossref
Guillermo Oliver & Peter Gruss. (1997) Current views on eye development. Trends in Neurosciences 20:9, pages 415-421.
Crossref
Melinda K. Duncan, Lidia Kos, Nancy A. Jenkins, Debra J. Gilbert, Neal G. Copeland & Stanislav I. Tomarev. (1997) Eyes absent: A gene family found in several metazoan phyla. Mammalian Genome 8:7, pages 479-485.
Crossref
Hongmin Sun, Andrei Rodin, Yihong Zhou, Douglas P. Dickinson, Donald E. Harper, David Hewett-Emmett & Wen-Hsiung Li. (1997) Evolution of paired domains: Isolation and sequencing of jellyfish and hydra Pax genes related to Pax-5 and  Pax-6 . Proceedings of the National Academy of Sciences 94:10, pages 5156-5161.
Crossref
G Sheng, E Thouvenot, D Schmucker, D S Wilson & C Desplan. (1997) Direct regulation of rhodopsin 1 by Pax-6/eyeless in Drosophila: evidence for a conserved function in photoreceptors.. Genes & Development 11:9, pages 1122-1131.
Crossref
D. Alan Underhill & Philippe Gros. (1997) The Paired-domain Regulates DNA Binding by the Homeodomain within the Intact Pax-3 Protein. Journal of Biological Chemistry 272:22, pages 14175-14182.
Crossref

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