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Molecular and Cellular Biology Volume 15, 1995 - Issue 8
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Research Article

A 32-Nucleotide Exon-Splicing Enhancer Regulates Usage of Competing 5′ Splice Sites in a Differential Internal Exon

Mary Beth Humphrey1 Department of Cell Biology, Baylor College of Medicine, Houston, Texas77030
,
Joseph Bryan1 Department of Cell Biology, Baylor College of Medicine, Houston, Texas77030
,
Thomas A. Cooper1 Department of Cell Biology, Baylor College of Medicine, Houston, Texas77030;2 Department of Pathology, Baylor College of Medicine, Houston, Texas77030
&
Susan M. Berget3 Verna and Marrs McClean Department of Biochemistry, Baylor College of Medicine, Houston, Texas77030
Pages 3979-3988 | Received 06 Jan 1995, Accepted 25 Apr 1995, Published online: 30 Mar 2023

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Petra Scamborova, Anthony Wong & Joan A. Steitz. (2004) An Intronic Enhancer Regulates Splicing of the Twintron of Drosophila melanogaster prospero Pre-mRNA by Two Different Spliceosomes. Molecular and Cellular Biology 24:5, pages 1855-1869.
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Sònia Guil, Renata Gattoni, Montserrat Carrascal, Joaquín Abián, James Stévenin & Montse Bach-Elias. (2003) Roles of hnRNP A1, SR Proteins, and p68 Helicase in c-H-ras Alternative Splicing Regulation. Molecular and Cellular Biology 23:8, pages 2927-2941.
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Martin J. Simard & Benoit Chabot. (2002) SRp30c Is a Repressor of 3′ Splice Site Utilization. Molecular and Cellular Biology 22:12, pages 4001-4010.
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Martin J. Simard & Benoit Chabot. (2000) Control of hnRNP A1 Alternative Splicing: an Intron Element Represses Use of the Common 3′ Splice Site. Molecular and Cellular Biology 20:19, pages 7353-7362.
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Qiang Wu & Adrian R. Krainer. (1999) AT-AC Pre-mRNA Splicing Mechanisms and Conservation of Minor Introns in Voltage-Gated Ion Channel Genes. Molecular and Cellular Biology 19:5, pages 3225-3236.
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Anand Gersappe & David J. Pintel. (1999) CA- and Purine-Rich Elements Form a Novel Bipartite Exon Enhancer Which Governs Inclusion of the Minute Virus of Mice NS2-Specific Exon in Both Singly and Doubly Spliced mRNAs. Molecular and Cellular Biology 19:1, pages 364-375.
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Hua Lou, Karla M. Neugebauer, Robert F. Gagel & Susan M. Berget. (1998) Regulation of Alternative Polyadenylation by U1 snRNPs and SRp20. Molecular and Cellular Biology 18:9, pages 4977-4985.
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Lisa M. McNally & Mark T. McNally. (1998) An RNA Splicing Enhancer-Like Sequence Is a Component of a Splicing Inhibitor Element from Rous Sarcoma Virus. Molecular and Cellular Biology 18:6, pages 3103-3111.
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Russ P. Carstens, Wallace L. McKeehan & Mariano A. Garcia-Blanco. (1998) An Intronic Sequence Element Mediates Both Activation and Repression of Rat Fibroblast Growth Factor Receptor 2 Pre-mRNA Splicing. Molecular and Cellular Biology 18:4, pages 2205-2217.
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Volker Heinrichs, Lisa C. Ryner & Bruce S. Baker. (1998) Regulation of Sex-Specific Selection of fruitless 5′ Splice Sites by transformerand transformer-2. Molecular and Cellular Biology 18:1, pages 450-458.
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Leslie L. Elrick, Mary Beth Humphrey, Thomas A. Cooper & Susan M. Berget. (1998) A Short Sequence within Two Purine-Rich Enhancers Determines 5′ Splice Site Specificity. Molecular and Cellular Biology 18:1, pages 343-352.
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Andrew J. McCullough & Susan M. Berget. (1997) G Triplets Located throughout a Class of Small Vertebrate Introns Enforce Intron Borders and Regulate Splice Site Selection. Molecular and Cellular Biology 17:8, pages 4562-4571.
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Keyong Du, Yong Peng, Linda E. Greenbaum, Barbara A. Haber & Rebecca Taub. (1997) HRS/SRp40-Mediated Inclusion of the Fibronectin EIIIB Exon, a Possible Cause of Increased EIIIB Expression in Proliferating Liver. Molecular and Cellular Biology 17:7, pages 4096-4104.
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Lydia R. Coulter, Mark A. Landree & Thomas A. Cooper. (1997) Identification of a New Class of Exonic Splicing Enhancers by In Vivo Selection. Molecular and Cellular Biology 17:4, pages 2143-2150.
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Chang Zhu, Jun Urano & Leslie R. Bell. (1997) The Sex-lethal Early Splicing Pattern Uses a Default Mechanism Dependent on the Alternative 5′ Splice Sites. Molecular and Cellular Biology 17:3, pages 1674-1681.
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Chiara Collesi, Massimo M. Santoro, Giovanni Gaudino & Paolo M. Comoglio. (1996) A Splicing Variant of the RON Transcript Induces Constitutive Tyrosine Kinase Activity and an Invasive Phenotype. Molecular and Cellular Biology 16:10, pages 5518-5526.
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Richard R. Gontarek & David Derse. (1996) Interactions among SR Proteins, an Exonic Splicing Enhancer, and a Lentivirus Rev Protein Regulate Alternative Splicing. Molecular and Cellular Biology 16:5, pages 2325-2331.
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Jacqueline Ramchatesingh, Alan M. Zahler, Karla M. Neugebauer, Mark B. Roth & Thomas A. Cooper. (1995) A Subset of SR Proteins Activates Splicing of the Cardiac Troponin T Alternative Exon by Direct Interactions with an Exonic Enhancer. Molecular and Cellular Biology 15:9, pages 4898-4907.
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Erming Wang, Neviana Dimova & Franca Cambi. (2007) PLP/DM20 ratio is regulated by hnRNPH and F and a novel G-rich enhancer in oligodendrocytes. Nucleic Acids Research 35:12, pages 4164-4178.
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Zhi-Ming Zheng. (2004) Regulation of alternative RNA splicing by exon definition and exon sequences in viral and mammalian gene expression. Journal of Biomedical Science 11:3, pages 278-294.
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Rebeca Martı́nez-Contreras, José Manuel Galindo, Arturo Aguilar-Rojas & Jesús Valdés. (2003) Two exonic elements in the flanking constitutive exons control the alternative splicing of the α exon of the ZO-1 pre-mRNA. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 1630:2-3, pages 71-83.
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Colin T. Shearn, Joy Walker & F.Anderson Norris. (2001) Identification of a Novel Spliceoform of Inositol Polyphosphate 4-Phosphatase Type Iα Expressed in Human Platelets: Structure of Human Inositol Polyphosphate 4-Phosphatase Type I Gene. Biochemical and Biophysical Research Communications 286:1, pages 119-125.
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Hye-kyung Chung & David Derse. (2001) Binding Sites for Rev and ASF/SF2 Map to a 55-Nucleotide Purine-rich Exonic Element in Equine Infectious Anemia Virus RNA*. Journal of Biological Chemistry 276:22, pages 18960-18967.
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Jin Han, Jae Young Seong, Kyungjin Kim, Wolfgang Wuttke & Hubertus Jarry. (2001) Analysis of exonic splicing enhancers in the mouse gonadotropin-releasing hormone (GnRH) gene. Molecular and Cellular Endocrinology 173:1-2, pages 157-166.
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Masaru Ichida, Yoji Hakamata, Morisada Hayakawa, Eriko Ueno, Uichi Ikeda, Kazuyuki Shimada, Toshiro Hamamoto, Yasuo Kagawa & Hitoshi Endo. (2000) Differential Regulation of Exonic Regulatory Elements for Muscle-specific Alternative Splicing during Myogenesis and Cardiogenesis. Journal of Biological Chemistry 275:21, pages 15992-16001.
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Michelle L. Hastings, Hema A. Ingle, Mitchell A. Lazar & Stephen H. Munroe. (2000) Post-transcriptional Regulation of Thyroid Hormone Receptor Expression by cis-Acting Sequences and a Naturally Occurring Antisense RNA. Journal of Biological Chemistry 275:15, pages 11507-11513.
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