2
Views
126
CrossRef citations to date
0
Altmetric
Research Article

A Subset of SR Proteins Activates Splicing of the Cardiac Troponin T Alternative Exon by Direct Interactions with an Exonic Enhancer

, , , &
Pages 4898-4907 | Received 23 Feb 1995, Accepted 13 Jun 1995, Published online: 30 Mar 2023

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (27)

Di Zhang, Mo-Xian Chen, Fu-Yuan Zhu, Jianhua Zhang & Ying-Gao Liu. (2020) Emerging Functions of Plant Serine/Arginine-Rich (SR) Proteins: Lessons from Animals. Critical Reviews in Plant Sciences 39:2, pages 173-194.
Read now
Arnd Hönig, Didier Auboeuf, Marjorie M. Parker, Bert W. O'Malley & Susan M. Berget. (2002) Regulation of Alternative Splicing by the ATP-Dependent DEAD-Box RNA Helicase p72. Molecular and Cellular Biology 22:16, pages 5698-5707.
Read now
Eric J. Wagner & Mariano A. Garcia-Blanco. (2001) Polypyrimidine Tract Binding Protein Antagonizes Exon Definition. Molecular and Cellular Biology 21:10, pages 3281-3288.
Read now
Ian C. Eperon, Olga V. Makarova, Akila Mayeda, Stephen H. Munroe, Javier F. Cáceres, Daniel G. Hayward & Adrian R. Krainer. (2000) Selection of Alternative 5′ Splice Sites: Role of U1 snRNP and Models for the Antagonistic Effects of SF2/ASF and hnRNP A1. Molecular and Cellular Biology 20:22, pages 8303-8318.
Read now
Russ P. Carstens, Eric J. Wagner & Mariano A. Garcia-Blanco. (2000) An Intronic Splicing Silencer Causes Skipping of the IIIb Exon of Fibroblast Growth Factor Receptor 2 through Involvement of Polypyrimidine Tract Binding Protein. Molecular and Cellular Biology 20:19, pages 7388-7400.
Read now
Hong-Xiang Liu, Shern L. Chew, Luca Cartegni, Michael Q. Zhang & Adrian R. Krainer. (2000) Exonic Splicing Enhancer Motif Recognized by Human SC35 under Splicing Conditions. Molecular and Cellular Biology 20:3, pages 1063-1071.
Read now
Sabine Guth, Concepción Martínez, Rajesh K. Gaur & Juan Valcárcel. (1999) Evidence for Substrate-Specific Requirement of the Splicing Factor U2AF35 and for Its Function after Polypyrimidine Tract Recognition by U2AF65. Molecular and Cellular Biology 19:12, pages 8263-8271.
Read now
Cyril F. Bourgeois, Michel Popielarz, Georges Hildwein & James Stevenin. (1999) Identification of a Bidirectional Splicing Enhancer: Differential Involvement of SR Proteins in 5′ or 3′ Splice Site Activation. Molecular and Cellular Biology 19:11, pages 7347-7356.
Read now
Akila Mayeda, Gavin R. Screaton, Sharon D. Chandler, Xiang-Dong Fu & Adrian R. Krainer. (1999) Substrate Specificities of SR Proteins in Constitutive Splicing Are Determined by Their RNA Recognition Motifs and Composite Pre-mRNA Exonic Elements. Molecular and Cellular Biology 19:3, pages 1853-1863.
Read now
Thomas D. Schaal & Tom Maniatis. (1999) Selection and Characterization of Pre-mRNA Splicing Enhancers: Identification of Novel SR Protein-Specific Enhancer Sequences. Molecular and Cellular Biology 19:3, pages 1705-1719.
Read now
Johann Soret, Renata Gattoni, Cécile Guyon, Alain Sureau, Michel Popielarz, Erwann Le Rouzic, Stéphanie Dumon, Françoise Apiou, Bernard Dutrillaux, Hartmut Voss, Wilhelm Ansorge, James Stévenin & Bernard Perbal. (1998) Characterization of SRp46, a Novel Human SR Splicing Factor Encoded by a PR264/SC35 Retropseudogene. Molecular and Cellular Biology 18:8, pages 4924-4934.
Read now
Lisa M. McNally & Mark T. McNally. (1998) An RNA Splicing Enhancer-Like Sequence Is a Component of a Splicing Inhibitor Element from Rous Sarcoma Virus. Molecular and Cellular Biology 18:6, pages 3103-3111.
Read now
Russ P. Carstens, Wallace L. McKeehan & Mariano A. Garcia-Blanco. (1998) An Intronic Sequence Element Mediates Both Activation and Repression of Rat Fibroblast Growth Factor Receptor 2 Pre-mRNA Splicing. Molecular and Cellular Biology 18:4, pages 2205-2217.
Read now
Volker Heinrichs, Lisa C. Ryner & Bruce S. Baker. (1998) Regulation of Sex-Specific Selection of fruitless 5′ Splice Sites by transformerand transformer-2. Molecular and Cellular Biology 18:1, pages 450-458.
Read now
Leslie L. Elrick, Mary Beth Humphrey, Thomas A. Cooper & Susan M. Berget. (1998) A Short Sequence within Two Purine-Rich Enhancers Determines 5′ Splice Site Specificity. Molecular and Cellular Biology 18:1, pages 343-352.
Read now
Fabienne Del Gatto, Ariane Plet, Marie-Claude Gesnel, Cécile Fort & Richard Breathnach. (1997) Multiple Interdependent Sequence Elements Control Splicing of a Fibroblast Growth Factor Receptor 2 Alternative Exon. Molecular and Cellular Biology 17:9, pages 5106-5116.
Read now
Andrew J. McCullough & Susan M. Berget. (1997) G Triplets Located throughout a Class of Small Vertebrate Introns Enforce Intron Borders and Regulate Splice Site Selection. Molecular and Cellular Biology 17:8, pages 4562-4571.
Read now
Keyong Du, Yong Peng, Linda E. Greenbaum, Barbara A. Haber & Rebecca Taub. (1997) HRS/SRp40-Mediated Inclusion of the Fibronectin EIIIB Exon, a Possible Cause of Increased EIIIB Expression in Proliferating Liver. Molecular and Cellular Biology 17:7, pages 4096-4104.
Read now
Charles C. Query, Patrick S. McCaw & Phillip A. Sharp. (1997) A Minimal Spliceosomal Complex A Recognizes the Branch Site and Polypyrimidine Tract. Molecular and Cellular Biology 17:5, pages 2944-2953.
Read now
Lydia R. Coulter, Mark A. Landree & Thomas A. Cooper. (1997) Identification of a New Class of Exonic Splicing Enhancers by In Vivo Selection. Molecular and Cellular Biology 17:4, pages 2143-2150.
Read now
Benoit Chabot, Marco Blanchette, Isabelle Lapierre & Hélène La Branche. (1997) An Intron Element Modulating 5′ Splice Site Selection in the hnRNP A1 Pre-mRNA Interacts with hnRNP A1. Molecular and Cellular Biology 17:4, pages 1776-1786.
Read now
Wan-Jiang Zhang & Jane Y. Wu. (1996) Functional Properties of p54, a Novel SR Protein Active in Constitutive and Alternative Splicing. Molecular and Cellular Biology 16:10, pages 5400-5408.
Read now
Kathryn J. Ryan & Thomas A. Cooper. (1996) Muscle-Specific Splicing Enhancers Regulate Inclusion of the Cardiac Troponin T Alternative Exon in Embryonic Skeletal Muscle. Molecular and Cellular Biology 16:8, pages 4014-4023.
Read now
Richard R. Gontarek & David Derse. (1996) Interactions among SR Proteins, an Exonic Splicing Enhancer, and a Lentivirus Rev Protein Regulate Alternative Splicing. Molecular and Cellular Biology 16:5, pages 2325-2331.
Read now

Articles from other publishers (99)

Emma R. Hinkle, R. Eric Blue, Yi-Hsuan Tsai, Matthew Combs, Jacquelyn Davi, Alisha R. Coffey, Aladin M. Boriek, Joan M. Taylor, Joel S. Parker & Jimena Giudice. (2022) Stretching muscle cells induces transcriptional and splicing transitions and changes in SR proteins. Communications Biology 5:1.
Crossref
Reuben J Pengelly, Dara Bakhtiar, Ivana Borovská, Jana Královičová & Igor Vořechovský. (2022) Exonic splicing code and protein binding sites for calcium. Nucleic Acids Research 50:10, pages 5493-5512.
Crossref
Geeng Loo ChongMung Hsia FooWen-Dar LinMin May WongPaul E. Verslues. (2019) Highly ABA-Induced 1 (HAI1)-Interacting protein HIN1 and drought acclimation-enhanced splicing efficiency at intron retention sites. Proceedings of the National Academy of Sciences 116:44, pages 22376-22385.
Crossref
Long-Fei Chen, Xiao-Long Han, Fen-Xiang Li, Yun-Ying Yao, Jin-Ping Fang, Xiao-Ju Liu, Xiao-Cong Li, Kun Wu, Min Liu & Xiao-Guang Chen. (2018) Comparative studies of Toxoplasma gondii transcriptomes: insights into stage conversion based on gene expression profiling and alternative splicing. Parasites & Vectors 11:1.
Crossref
Yun Ju KimRuozhong WangLei GaoDongming LiChi XuHyunggon MangJien JeonXiangsong ChenXuehua Zhong, June M. KwakBeixin MoLangtao XiaoXuemei Chen. (2016) POWERDRESS and HDA9 interact and promote histone H3 deacetylation at specific genomic sites in Arabidopsis . Proceedings of the National Academy of Sciences 113:51, pages 14858-14863.
Crossref
Shu Lu & Xiaomin Yin. (2016) Overexpression of Dyrk1A regulates cardiac troponin T splicing in cells and mice. Biochemical and Biophysical Research Communications 473:4, pages 993-998.
Crossref
Chen Gao, Shuxun Ren, Jae-Hyung Lee, Jinsong Qiu, Douglas J. Chapski, Christoph D. Rau, Yu Zhou, Maha Abdellatif, Astushi Nakano, Thomas M. Vondriska, Xinshu Xiao, Xiang-Dong Fu, Jau-Nian Chen & Yibin Wang. (2015) RBFox1-mediated RNA splicing regulates cardiac hypertrophy and heart failure. Journal of Clinical Investigation 126:1, pages 195-206.
Crossref
Shiri Eshar, Lindsey Altenhofen, Alona Rabner, Phil Ross, Yair Fastman, Yael Mandel-Gutfreund, Rotem Karni, Manuel Llinás & Ron Dzikowski. (2015) PfSR1 controls alternative splicing and steady-state RNA levels in P lasmodium falciparum through preferential recognition of specific RNA motifs . Molecular Microbiology 96:6, pages 1283-1297.
Crossref
Jonathan M. Howard & Jeremy R. Sanford. (2015) The RNAissance family: SR proteins as multifaceted regulators of gene expression. Wiley Interdisciplinary Reviews: RNA 6:1, pages 93-110.
Crossref
Jonas Maaskola & Nikolaus Rajewsky. (2014) Binding site discovery from nucleic acid sequences by discriminative learning of hidden Markov models. Nucleic Acids Research 42:21, pages 12995-13011.
Crossref
Chiung-Yun Chang, Wen-Dar Lin & Shih-Long Tu. (2014) Genome-Wide Analysis of Heat-Sensitive Alternative Splicing in Physcomitrella patens       . Plant Physiology 165:2, pages 826-840.
Crossref
Chen Gao & Yibin Wang. (2012) Global impact of RNA splicing on transcriptome remodeling in the heart. Journal of Zhejiang University SCIENCE B 13:8, pages 603-608.
Crossref
Xin Wang, Liran Juan, Junjie Lv, Kejun Wang, Jeremy R Sanford & Yunlong Liu. (2011) Predicting sequence and structural specificities of RNA binding regions recognized by splicing factor SRSF1. BMC Genomics 12:S5.
Crossref
Jana Kralovicova, Gyulin Hwang, A. Charlotta Asplund, Alexander Churbanov, C. I. Edvard Smith & Igor Vorechovsky. (2011) Compensatory signals associated with the activation of human GC 5′ splice sites. Nucleic Acids Research 39:16, pages 7077-7091.
Crossref
Xinshu Xiao & Jae‐Hyung Lee. (2010) Systems analysis of alternative splicing and its regulation. WIREs Systems Biology and Medicine 2:5, pages 550-565.
Crossref
Minna-Liisa Änkö, Lucia Morales, Ian Henry, Andreas Beyer & Karla M Neugebauer. (2010) Global analysis reveals SRp20- and SRp75-specific mRNPs in cycling and neural cells. Nature Structural & Molecular Biology 17:8, pages 962-970.
Crossref
Igor Vorechovsky. (2009) Transposable elements in disease-associated cryptic exons. Human Genetics 127:2, pages 135-154.
Crossref
Jeremy R. Sanford, Xin Wang, Matthew Mort, Natalia VanDuyn, David N. Cooper, Sean D. Mooney, Howard J. Edenberg & Yunlong Liu. (2009) Splicing factor SFRS1 recognizes a functionally diverse landscape of RNA transcripts. Genome Research 19:3, pages 381-394.
Crossref
T. D. Baughan, A. Dickson, E. Y. Osman & C. L. Lorson. (2009) Delivery of bifunctional RNAs that target an intronic repressor and increase SMN levels in an animal model of spinal muscular atrophy. Human Molecular Genetics 18:9, pages 1600-1611.
Crossref
Jennifer C. LongJavier F. Caceres. (2008) The SR protein family of splicing factors: master regulators of gene expression. Biochemical Journal 417:1, pages 15-27.
Crossref
Jeremy R. Sanford, Pedro Coutinho, Jamie A. Hackett, Xin Wang, William Ranahan & Javier F. Caceres. (2008) Identification of Nuclear and Cytoplasmic mRNA Targets for the Shuttling Protein SF2/ASF. PLoS ONE 3:10, pages e3369.
Crossref
Elena Vela, Josep M. Hilari, Xavier Roca, Ana M. Muñoz-Mármol, Aurelio Ariza & Marcos Isamat. (2007) Multisite and bidirectional exonic splicing enhancer in CD44 alternative exon v3 . RNA 13:12, pages 2312-2323.
Crossref
Jana Královičová & Igor Vořechovský. (2007) Global control of aberrant splice-site activation by auxiliary splicing sequences: evidence for a gradient in exon and intron definition. Nucleic Acids Research 35:19, pages 6399-6413.
Crossref
Ralf Bortfeldt, Alexander Herrmann, Heike Pospisil & Stefan Schuster. 2007. Mathematical Modeling of Biological Systems. Mathematical Modeling of Biological Systems 337 349 .
Trine Elkjaer Crovato & Jan Egebjerg. (2005) ASF/SF2 and SC35 regulate the glutamate receptor subunit 2 alternative flip/flop splicing. FEBS Letters 579:19, pages 4138-4144.
Crossref
Jean-Vincent Chamary & Laurence D. Hurst. (2005) Biased codon usage near intron-exon junctions: selection on splicing enhancers, splice-site recognition or something else?. Trends in Genetics 21:5, pages 256-259.
Crossref
Christopher J. Webb, Charles M. Romfo, Willem J. van Heeckeren & Jo Ann Wise. (2005) Exonic splicing enhancers in fission yeast: functional conservation demonstrates an early evolutionary origin. Genes & Development 19:2, pages 242-254.
Crossref
Delphine Ropers, Lilia Ayadi, Renata Gattoni, Sandrine Jacquenet, Laurence Damier, Christiane Branlant & James Stévenin. (2004) Differential Effects of the SR Proteins 9G8, SC35, ASF/SF2, and SRp40 on the Utilization of the A1 to A5 Splicing Sites of HIV-1 RNA. Journal of Biological Chemistry 279:29, pages 29963-29973.
Crossref
Zhi-Ming Zheng. (2004) Regulation of alternative RNA splicing by exon definition and exon sequences in viral and mammalian gene expression. Journal of Biomedical Science 11:3, pages 278-294.
Crossref
Niketa A. Patel, Hercules S. Apostolatos, Konrad Mebert, Charles E. Chalfant, James E. Watson, T. S. Pillay, Janet Sparks & Denise R. Cooper. (2004) Insulin Regulates Protein Kinase CβII Alternative Splicing in Multiple Target Tissues: Development of a Hormonally Responsive Heterologous Minigene. Molecular Endocrinology 18:4, pages 899-911.
Crossref
Audrey McAlinden, Necat Havlioglu & Linda J. Sandell. (2004) Regulation of protein diversity by alternative pre-mRNA splicing with specific focus on chondrogenesis. Birth Defects Research Part C: Embryo Today: Reviews 72:1, pages 51-68.
Crossref
Cyril F Bourgeois, Fabrice Lejeune & James Stévenin. 2004. 37 88 .
Rebeca Martı́nez-Contreras, José Manuel Galindo, Arturo Aguilar-Rojas & Jesús Valdés. (2003) Two exonic elements in the flanking constitutive exons control the alternative splicing of the α exon of the ZO-1 pre-mRNA. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 1630:2-3, pages 71-83.
Crossref
Douglas L. Black. (2003) Mechanisms of Alternative Pre-Messenger RNA Splicing. Annual Review of Biochemistry 72:1, pages 291-336.
Crossref
P. Förch & J. Valcárcel. 2003. Regulation of Alternative Splicing. Regulation of Alternative Splicing 127 151 .
Raymund Stefancsik, Jeffrey D. Randall, Chengjian Mao & Satyapriya Sarkar. (2003) Structure and Sequence of the Human Fast Skeletal Troponin T (TNNT3) Gene: Insight Into the Evolution of the Gene and the Origin of the Developmentally Regulated Isoforms. Comparative and Functional Genomics 4:6, pages 609-625.
Crossref
Malcolm J. Gardner, Shamira J. Shallom, Jane M. Carlton, Steven L. Salzberg, Vishvanath Nene, Azadeh Shoaibi, Anne Ciecko, Jeffery Lynn, Michael Rizzo, Bruce Weaver, Behnam Jarrahi, Michael Brenner, Babak Parvizi, Luke Tallon, Azita Moazzez, David Granger, Claire Fujii, Cheryl Hansen, James Pederson, Tamara Feldblyum, Jeremy Peterson, Bernard Suh, Sam Angiuoli, Mihaela Pertea, Jonathan Allen, Jeremy Selengut, Owen White, Leda M. Cummings, Hamilton O. Smith, Mark D. Adams, J. Craig Venter, Daniel J. Carucci, Stephen L. Hoffman & Claire M. Fraser. (2002) Sequence of Plasmodium falciparum chromosomes 2, 10, 11 and 14. Nature 419:6906, pages 531-534.
Crossref
Massimo Caputi, Raymond J. KendziorJr.Jr. & Karen L. Beemon. (2002) A nonsense mutation in the fibrillin-1 gene of a Marfan syndrome patient induces NMD and disrupts an exonic splicing enhancer . Genes & Development 16:14, pages 1754-1759.
Crossref
Joon No Lee, Soo-Han Bae & Young-Ki Paik. (2002) Structure and alternative splicing of the rat 7-dehydrocholesterol reductase gene. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 1576:1-2, pages 148-156.
Crossref
Alison J. Pollard, Adrian R. Krainer, Stephen C. Robson & G. Nicholas Europe-Finner. (2002) Alternative Splicing of the Adenylyl Cyclase Stimulatory G-protein Gαs Is Regulated by SF2/ASF and Heterogeneous Nuclear Ribonucleoprotein A1 (hnRNPA1) and Involves the Use of an Unusual TG 3′-Splice Site. Journal of Biological Chemistry 277:18, pages 15241-15251.
Crossref
Luca Cartegni, Shern L. Chew & Adrian R. Krainer. (2002) Listening to silence and understanding nonsense: exonic mutations that affect splicing. Nature Reviews Genetics 3:4, pages 285-298.
Crossref
Morisada Hayakawa, Eiji Sakashita, Eriko Ueno, Shin-ichi Tominaga, Toshiro Hamamoto, Yasuo Kagawa & Hitoshi Endo. (2002) Muscle-specific Exonic Splicing Silencer for Exon Exclusion in Human ATP Synthase γ-Subunit Pre-mRNA. Journal of Biological Chemistry 277:9, pages 6974-6984.
Crossref
Philip J. Smith, Emma L. Spurrell, John Coakley, Charles J. Hinds, Richard J. M. Ross, Adrian R. Krainer & Shern L. Chew. (2002) An Exonic Splicing Enhancer in Human IGF-I Pre-mRNA Mediates Recognition of Alternative Exon 5 by the Serine-Arginine Protein Splicing Factor-2/ Alternative Splicing Factor. Endocrinology 143:1, pages 146-154.
Crossref
Bruce A. Kuo, Tatiana M. Uporova, Hongyan Liang, Vickie D. Bennett, Rocky S. Tuan & Pamela A. Norton. (2002) Alternative splicing during chondrogenesis: Modulation of fibronectin exon EIIIA splicing by SR proteins. Journal of Cellular Biochemistry 86:1, pages 45-55.
Crossref
Thomas Ø Tange & Jørgen Kjems. (2001) SF2/ASF binds to a splicing enhancer in the third HIV-1 tat exon and stimulates U2AF binding independently of the RS domain. Journal of Molecular Biology 312:4, pages 649-662.
Crossref
C P Matthews, K Shera, N Kiviat & J K McDougall. (2001) Expression of truncated FHIT transcripts in cervical cancers and in normal human cells. Oncogene 20:34, pages 4665-4675.
Crossref
Fuminari IshibashiTomoyuki MizukamiShiro KanegasakiLena MotodaRyota KakinumaFumio EndoHiroyuki Nunoi. (2001) Improved superoxide-generating ability by interferon γ due to splicing pattern change of transcripts in neutrophils from patients with a splice site mutation inCYBB gene. Blood 98:2, pages 436-441.
Crossref
Nova Fong & David L. Bentley. (2001) Capping, splicing, and 3′ processing are independently stimulated by RNA polymerase II: different functions for different segments of the CTD. Genes & Development 15:14, pages 1783-1795.
Crossref
David M Standiford, Wei Tao Sun, Mary Beth Davis & Charles P EmersonJr.Jr.. (2001) Positive and Negative Intronic Regulatory Elements Control Muscle-Specific Alternative Exon Splicing of Drosophila Myosin Heavy Chain Transcripts. Genetics 157:1, pages 259-271.
Crossref
Zhi-Ming Zheng, Eric S. Reid & Carl C. Baker. (2000) Utilization of the Bovine Papillomavirus Type 1 Late-Stage-Specific Nucleotide 3605 3′ Splice Site Is Modulated by a Novel Exonic Bipartite Regulator but Not by an Intronic Purine-Rich Element. Journal of Virology 74:22, pages 10612-10622.
Crossref
Keizo Tomonaga, Takeshi Kobayashi, Byeong- Jae Lee, Makiko Watanabe, Wataru Kamitani & Kazuyoshi Ikuta. (2000) Identification of alternative splicing and negative splicing activity of a nonsegmented negative-strand RNA virus, Borna disease virus. Proceedings of the National Academy of Sciences 97:23, pages 12788-12793.
Crossref
Wessel P. Dirksen, Xinlan Li, Akila Mayeda, Adrian R. Krainer & Fritz M. Rottman. (2000) Mapping the SF2/ASF Binding Sites in the Bovine Growth Hormone Exonic Splicing Enhancer. Journal of Biological Chemistry 275:37, pages 29170-29177.
Crossref
Zhi-Ming Zheng, Jesse Quintero, Eric S. Reid, Christian Gocke & Carl C. Baker. (2000) Optimization of a Weak 3′ Splice Site Counteracts the Function of a Bovine Papillomavirus Type 1 Exonic Splicing Suppressor In Vitro and In Vivo. Journal of Virology 74:13, pages 5902-5910.
Crossref
Franco Pagani, Emanuele Buratti, Cristiana Stuani, Maurizio Romano, Elisabetta Zuccato, Martina Niksic, Luisella Giglio, Dino Faraguna & Francisco E. Baralle. (2000) Splicing Factors Induce Cystic Fibrosis Transmembrane Regulator Exon 9 Skipping through a Nonevolutionary Conserved Intronic Element. Journal of Biological Chemistry 275:28, pages 21041-21047.
Crossref
Kathryn J. Ryan, Nicolas Charlet-B.Thomas A. Cooper. (2000) Binding of PurH to a Muscle-specific Splicing Enhancer Functionally Correlates with Exon Inclusion in Vivo. Journal of Biological Chemistry 275:27, pages 20618-20626.
Crossref
Taizo Kawano, Masaki Fujita & Hiroshi Sakamoto. (2000) Unique and redundant functions of SR proteins, a conserved family of splicing factors, in Caenorhabditis elegans development. Mechanisms of Development 95:1-2, pages 67-76.
Crossref
Meihua Tu, Weida Tong, Roger Perkins & Carrie R Valentine. (2000) Predicted changes in pre-mRNA secondary structure vary in their association with exon skipping for mutations in exons 2, 4, and 8 of the Hprt gene and exon 51 of the fibrillin gene. Mutation Research/Mutation Research Genomics 432:1-2, pages 15-32.
Crossref
Leslie A. Goldstein & Wen-Tien Chen. (2000) Identification of an Alternatively Spliced Seprase mRNA That Encodes a Novel Intracellular Isoform. Journal of Biological Chemistry 275:4, pages 2554-2559.
Crossref
Robert J. KelmJr.Jr., Paula K. Elder & Michael J. Getz. (1999) The Single-stranded DNA-binding Proteins, Purα, Purβ, and MSY1 Specifically Interact with an Exon 3-derived Mouse Vascular Smooth Muscle α-Actin Messenger RNA Sequence. Journal of Biological Chemistry 274:53, pages 38268-38275.
Crossref
Maxim Golovkin & Anireddy S.N. Reddy. (1999) An SC35-like Protein and a Novel Serine/Arginine-rich Protein Interact with Arabidopsis U1-70K Protein. Journal of Biological Chemistry 274:51, pages 36428-36438.
Crossref
Jeremy M. Stark, Thomas A. Cooper & Mark B. Roth. (1999) The Relative Strengths of SR Protein-mediated Associations of Alternative and Constitutive Exons Can Influence Alternative Splicing. Journal of Biological Chemistry 274:42, pages 29838-29842.
Crossref
Shern L. Chew, Hong-Xiang Liu, Akila Mayeda & Adrian R. Krainer. (1999) Evidence for the function of an exonic splicing enhancer after the first catalytic step of pre-mRNA splicing. Proceedings of the National Academy of Sciences 96:19, pages 10655-10660.
Crossref
Anne-Marie Pret, Laurent Balvay & Marc Y. Fiszman. (1999) Regulated Splicing of an Alternative Exon of beta-Tropomyosin Pre-mRNAs in Myogenic Cells Depends on the Strength of Pyrimidine-Rich Intronic Enhancer Elements. DNA and Cell Biology 18:9, pages 671-683.
Crossref
Hassan Jumaa, Grace Wei & Peter J Nielsen. (1999) Blastocyst formation is blocked in mouse embryos lacking the splicing factor SRp20. Current Biology 9:16, pages 899-902.
Crossref
Raphael Lemaire, Annabelle Winne, Madathia Sarkissian & Robert Lafyatis. (1999) SF2 and SRp55 regulation of CD45 exon 4 skipping during T cell activation. European Journal of Immunology 29:3, pages 823-837.
Crossref
Zhi Ming Zheng, Pei-jun He & Carl C. Baker. (1999) Function of a Bovine Papillomavirus Type 1 Exonic Splicing Suppressor Requires a Suboptimal Upstream 3′ Splice Site. Journal of Virology 73:1, pages 29-36.
Crossref
E. Labourier, E. Allemand, S. Brand, M. Fostier, J. Tazi & H.-M. Bourbon. (1999) Recognition of exonic splicing enhancer sequences by the Drosophila splicing repressor RSF1. Nucleic Acids Research 27:11, pages 2377-2386.
Crossref
Dianne Hodges, Richard M Cripps, Martin E O'Connor & Sanford I Bernstein. (1999) The Role of Evolutionarily Conserved Sequences in Alternative Splicing at the 3′ End of Drosophila melanogaster Myosin Heavy Chain RNA. Genetics 151:1, pages 263-276.
Crossref
A. Javier Lopez. (1998) ALTERNATIVE SPLICING OF PRE-mRNA: Developmental Consequences and Mechanisms of Regulation. Annual Review of Genetics 32:1, pages 279-305.
Crossref
Keyong Du, Julia I. Leu, Yong Peng & Rebecca Taub. (1998) Transcriptional Up-regulation of the Delayed Early GeneHRS/SRp40during Liver Regeneration. Journal of Biological Chemistry 273:52, pages 35208-35215.
Crossref
Zhi Ming Zheng, Martijn Huynen & Carl C. Baker. (1998) A pyrimidine-rich exonic splicing suppressor binds multiple RNA splicing factors and inhibits spliceosome assembly. Proceedings of the National Academy of Sciences 95:24, pages 14088-14093.
Crossref
Shou-Hua Xiao & James L. Manley. (1998) Phosphorylation-dephosphorylation differentially affects activities of splicing factor ASF/SF2. The EMBO Journal 17:21, pages 6359-6367.
Crossref
A.F. Muro, A. Iaconcig & F.E. Baralle. (1998) Regulation of the fibronectin EDA exon alternative splicing. Cooperative role of the exonic enhancer element and the 5′ splicing site. FEBS Letters 437:1-2, pages 137-141.
Crossref
Carrie R Valentine. (1998) The association of nonsense codons with exon skipping. Mutation Research/Reviews in Mutation Research 411:2, pages 87-117.
Crossref
Jin Wang, Shou-Hua Xiao & James L. Manley. (1998) Genetic analysis of the SR protein ASF/SF2: interchangeability of RS domains and negative control of splicing. Genes & Development 12:14, pages 2222-2233.
Crossref
Hong-Xiang Liu, Michael Zhang & Adrian R. Krainer. (1998) Identification of functional exonic splicing enhancer motifs recognized by individual SR proteins. Genes & Development 12:13, pages 1998-2012.
Crossref
Atsushi Kosaki, James Nelson & Nicholas J.G. Webster. (1998) Identification of Intron and Exon Sequences Involved in Alternative Splicing of Insulin Receptor Pre-mRNA. Journal of Biological Chemistry 273:17, pages 10331-10337.
Crossref
Roland Tacke, Masaya Tohyama, Satoshi Ogawa & James L Manley. (1998) Human Tra2 Proteins Are Sequence-Specific Activators of Pre-mRNA Splicing. Cell 93:1, pages 139-148.
Crossref
Jeremy M. Stark, David P. Bazett-Jones, Manfred Herfort & Mark B. Roth. (1998) SR proteins are sufficient for exon bridging across an intron. Proceedings of the National Academy of Sciences 95:5, pages 2163-2168.
Crossref
Z M Zheng, P J He & C C Baker. (1997) Structural, functional, and protein binding analyses of bovine papillomavirus type 1 exonic splicing enhancers. Journal of Virology 71:12, pages 9096-9107.
Crossref
M P WentzB E MooreM W CloydS M BergetL A Donehower. (1997) A naturally arising mutation of a potential silencer of exon splicing in human immunodeficiency virus type 1 induces dominant aberrant splicing and arrests virus production. Journal of Virology 71:11, pages 8542-8551.
Crossref
D Y HwangJ B Cohen. (1997) A splicing enhancer in the 3'-terminal c-H-ras exon influences mRNA abundance and transforming activity. Journal of Virology 71:9, pages 6416-6426.
Crossref
Thomas A. Cooper & William Mattox. (1997) The Regulation of Splice-Site Selection, and Its Role in Human Disease. The American Journal of Human Genetics 61:2, pages 259-266.
Crossref
Karin AndersonMelissa J. Moore. (1997) Bimolecular Exon Ligation by the Human Spliceosome. Science 276:5319, pages 1712-1716.
Crossref
K M Neugebauer & M B Roth. (1997) Distribution of pre-mRNA splicing factors at sites of RNA polymerase II transcription.. Genes & Development 11:9, pages 1148-1159.
Crossref
H Min, C W Turck, J M Nikolic & D L Black. (1997) A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer.. Genes & Development 11:8, pages 1023-1036.
Crossref
A. J. McCullough & M. A. Schuler. (1997) Intronic and Exonic Sequences Modulate 5' Splice Site Selection in Plant Nuclei. Nucleic Acids Research 25:5, pages 1071-1077.
Crossref
Roland Tacke, Yan Chen & James L. Manley. (1997) Sequence-specific RNA binding by an SR protein requires RS domain phosphorylation: Creation of an SRp40-specific splicing enhancer. Proceedings of the National Academy of Sciences 94:4, pages 1148-1153.
Crossref
Volker Heinrichs & Bruce S. Baker. (1997) In vivo analysis of the functional domains of the Drosophila splicing regulator RBP1 . Proceedings of the National Academy of Sciences 94:1, pages 115-120.
Crossref
C. R. Cook & M. T. McNally. (1996) Characterization of an RNP Complex That Assembles on the Rous Sarcoma Virus Negative Regulator of Splicing Element. Nucleic Acids Research 24:24, pages 4962-4968.
Crossref
Madathia Sarkissian, Annabelle Winne & Robert Lafyatis. (1996) The Mammalian Homolog of Suppressor-of-white-apricot Regulates Alternative mRNA Splicing of CD45 Exon 4 and Fibronectin IIICS. Journal of Biological Chemistry 271:49, pages 31106-31114.
Crossref
Benoit Chabot. (1996) Directing alternative splicing: cast and scenarios. Trends in Genetics 12:11, pages 472-478.
Crossref
J Wang, Y Takagaki & J L Manley. (1996) Targeted disruption of an essential vertebrate gene: ASF/SF2 is required for cell viability.. Genes & Development 10:20, pages 2588-2599.
Crossref
K W Lynch & T Maniatis. (1996) Assembly of specific SR protein complexes on distinct regulatory elements of the Drosophila doublesex splicing enhancer.. Genes & Development 10:16, pages 2089-2101.
Crossref
Juan Valcárcel & Michael R. Green. (1996) The SR protein family: pleiotropic functions in pre-mRNA splicing. Trends in Biochemical Sciences 21:8, pages 296-301.
Crossref
Z M ZhengP HeC C Baker. (1996) Selection of the bovine papillomavirus type 1 nucleotide 3225 3' splice site is regulated through an exonic splicing enhancer and its juxtaposed exonic splicing suppressor. Journal of Virology 70:7, pages 4691-4699.
Crossref
Melissa D Adams, David Z Rudner & Donald C Rio. (1996) Biochemistry and regulation of pre-mRNA splicing. Current Opinion in Cell Biology 8:3, pages 331-339.
Crossref
Robin Reed. (1996) Initial splice-site recognition and pairing during pre-mRNA splicing. Current Opinion in Genetics & Development 6:2, pages 215-220.
Crossref
M.E. Gallego, P. Sirand-Pugnet, P. Durosay, B. Clouet d'Orval, Y. d'Aubenton-Carafa, E. Brody, A. Expert-Bezançon & J. Marie. (1996) Tissue-specific splicing of two mutually exclusive exons of the chicken β-tropomyosin pre-mRNA: Positive and negative regulations. Biochimie 78:6, pages 457-465.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.