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Research Article

Identification and Analysis of a Functional Human Homolog of the SPT4 Gene of Saccharomyces cerevisiae

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Pages 2848-2856 | Received 28 Dec 1995, Accepted 07 Mar 1996, Published online: 29 Mar 2023

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Read on this site (3)

Dmitri Ivanov, Youn Tae Kwak, Jun Guo & Richard B. Gaynor. (2000) Domains in the SPT5 Protein That Modulate Its Transcriptional Regulatory Properties. Molecular and Cellular Biology 20:9, pages 2970-2983.
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Munira A. Basrai, Jeffrey Kingsbury, Douglas Koshland, Forrest Spencer & Philip Hieter. (1996) Faithful Chromosome Transmission Requires Spt4p, a Putative Regulator of Chromatin Structure in Saccharomyces cerevisiae. Molecular and Cellular Biology 16:6, pages 2838-2847.
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Articles from other publishers (27)

Alejandro Collin, Araceli González-Jiménez, María del Carmen González-Jiménez, Manuel J. Alfonso & Olga Calvo. (2022) The Role of S. cerevisiae Sub1/PC4 in Transcription Elongation Depends on the C-Terminal Region and Is Independent of the ssDNA Binding Domain. Cells 11:20, pages 3320.
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Preeti Dabas. 2022. Gene Expression. Gene Expression.
Ashutosh Shukla, Nora-Guadalupe P. Ramirez & Iván D’Orso. (2020) HIV-1 Proviral Transcription and Latency in the New Era. Viruses 12:5, pages 555.
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Xiaorong Zhang, G. Paul H. van Heusden & Paul J. J. Hooykaas. (2017) Virulence protein VirD5 of Agrobacterium tumefaciens binds to kinetochores in host cells via an interaction with Spt4 . Proceedings of the National Academy of Sciences 114:38, pages 10238-10243.
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Prashant K. Mishra, Jiasheng Guo, Lauren E. Dittman, Julian Haase, Elaine Yeh, Kerry Bloom & Munira A. Basrai. (2015) Pat1 protects centromere-specific histone H3 variant Cse4 from Psh1-mediated ubiquitination. Molecular Biology of the Cell 26:11, pages 2067-2079.
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Prashant K Mishra, Alicia R Ottmann & Munira A Basrai. (2013) Structural Integrity of Centromeric Chromatin and Faithful Chromosome Segregation Requires Pat1. Genetics 195:2, pages 369-379.
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Trent Fowler, Hyunsuk Suh, Stephen Buratowski & Ananda L. Roy. (2013) Regulation of Primary Response Genes in B Cells. Journal of Biological Chemistry 288:21, pages 14906-14916.
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Grant A. Hartzog & Jianhua Fu. (2013) The Spt4–Spt5 complex: A multi-faceted regulator of transcription elongation. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1829:1, pages 105-115.
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Alicia García, Alejandro Collin & Olga Calvo. (2012) Sub1 associates with Spt5 and influences RNA polymerase II transcription elongation rate. Molecular Biology of the Cell 23:21, pages 4297-4312.
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Chia-Rung Liu, Chuang-Rung Chang, Yijuang Chern, Tzu-Han Wang, Wen-Chieh Hsieh, Wen-Chuan Shen, Chi-Yuan Chang, I-Chieh Chu, Ning Deng, Stanley N. Cohen & Tzu-Hao Cheng. (2012) Spt4 Is Selectively Required for Transcription of Extended Trinucleotide Repeats. Cell 148:4, pages 690-701.
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Beate Schwer, Susanne Schneider, Yi Pei, Anna Aronova & Stewart Shuman. (2009) Characterization of the Schizosaccharomyces pombe Spt5-Spt4 complex . RNA 15:7, pages 1241-1250.
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Sabine Wenzel, Kristian Schweimer, Paul Rösch & Birgitta M. Wöhrl. (2008) The small hSpt4 subunit of the human transcription elongation factor DSIF is a Zn-finger protein with α/β type topology. Biochemical and Biophysical Research Communications 370:3, pages 414-418.
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Luciana B Crotti & Munira A Basrai. (2004) Functional roles for evolutionarily conserved Spt4p at centromeres and heterochromatin in Saccharomyces cerevisiae. The EMBO Journal 23:8, pages 1804-1814.
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Grant A Hartzog, Jennifer L Speer & Derek L Lindstrom. (2002) Transcript elongation on a nucleoprotein template. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 1577:2, pages 276-286.
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Derek L Lindstrom & Grant A Hartzog. (2001) Genetic Interactions of Spt4-Spt5 and TFIIS With the RNA Polymerase II CTD and CTD Modifying Enzymes in Saccharomyces cerevisiae . Genetics 159:2, pages 487-497.
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Anwarul Ferdous, Fernando Gonzalez, Liping Sun, Thomas Kodadek & Stephen Albert Johnston. (2001) The 19S Regulatory Particle of the Proteasome Is Required for Efficient Transcription Elongation by RNA Polymerase II. Molecular Cell 7:5, pages 981-991.
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Alvaro Puga, Andrew Maier & Mario Medvedovic. (2000) The transcriptional signature of dioxin in human hepatoma HepG2 cells. Biochemical Pharmacology 60:8, pages 1129-1142.
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Tadashi Wada, George Orphanides, Jun Hasegawa, Dong-Ki Kim, Daisuke Shima, Yuki Yamaguchi, Aya Fukuda, Koji Hisatake, Sangtaek Oh, Danny Reinberg & Hiroshi Handa. (2000) FACT Relieves DSIF/NELF-Mediated Inhibition of Transcriptional Elongation and Reveals Functional Differences between P-TEFb and TFIIH. Molecular Cell 5:6, pages 1067-1072.
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Melody S. Clark. 2000. Comparative Genomics. Comparative Genomics 1 22 .
Yuki Yamaguchi, Toshiyuki Takagi, Tadashi Wada, Keiichi Yano, Akiko Furuya, Seiji Sugimoto, Jun Hasegawa & Hiroshi Handa. (1999) NELF, a Multisubunit Complex Containing RD, Cooperates with DSIF to Repress RNA Polymerase II Elongation. Cell 97:1, pages 41-51.
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Yuki Yamaguchi, Tadashi Wada, Daisuke Watanabe, Toshiyuki Takagi, Jun Hasegawa & Hiroshi Handa. (1999) Structure and Function of the Human Transcription Elongation Factor DSIF. Journal of Biological Chemistry 274:12, pages 8085-8092.
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M.S. Clark. (1999) Comparative genomics: the key to understanding the human genome project. BioEssays 21:2, pages 121-130.
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Michael Hampsey. (1998) Molecular Genetics of the RNA Polymerase II General Transcriptional Machinery. Microbiology and Molecular Biology Reviews 62:2, pages 465-503.
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Foon Wu-Baer, William S Lane & Richard B Gaynor. (1998) Role of the human homolog of the yeast transcription factor SPT5 in HIV-1 tat-activation. Journal of Molecular Biology 277:2, pages 179-197.
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Yuki Yamaguchi, Tadashi Wada & Hiroshi Handa. (2001) Interplay between positive and negative elongation factors: drawing a new view of DRB. Genes to Cells 3:1, pages 9-15.
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Paul A. Moore. 1998. Yeast Gene Analysis. Yeast Gene Analysis 417 430 .
Axel A Stachora, Ramón Enrı́quez Schäfer, Matthias Pohlmeier, Gernot Maier & Herwig Ponstingl. (1997) Human Supt5h protein, a putative modulator of chromatin structure, is reversibly phosphorylated in mitosis. FEBS Letters 409:1, pages 74-78.
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