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Molecular and Cellular Biology Volume 16, 1996 - Issue 9
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Research Article

Characterizing Replication Intermediates in the Amplified CHO Dihydrofolate Reductase Domain by Two Novel Gel Electrophoretic Techniques

Robert F. Kalejta1 Department of Biochemistry, University of Virginia School of Medicine, Charlottesville, Virginia22908;2 Cell and Molecular Biology Program, University of Virginia School of Medicine, Charlottesville, Virginia22908
,
Hong-Bo Lin1 Department of Biochemistry, University of Virginia School of Medicine, Charlottesville, Virginia22908
,
Pieter A. Dijkwel1 Department of Biochemistry, University of Virginia School of Medicine, Charlottesville, Virginia22908
&
Joyce L. Hamlin1 Department of Biochemistry, University of Virginia School of Medicine, Charlottesville, Virginia22908;2 Cell and Molecular Biology Program, University of Virginia School of Medicine, Charlottesville, Virginia22908Correspondence[email protected]
Pages 4923-4931 | Received 01 May 1996, Accepted 24 Jun 1996, Published online: 29 Mar 2023

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Shuntai Wang, Pieter A. Dijkwel & Joyce L. Hamlin. (1998) Lagging-Strand, Early-Labelling, and Two-Dimensional Gel Assays Suggest Multiple Potential Initiation Sites in the Chinese Hamster Dihydrofolate Reductase Origin. Molecular and Cellular Biology 18:1, pages 39-50.
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Robert F. Kalejta & Joyce L. Hamlin. (1996) Composite Patterns in Neutral/Neutral Two-Dimensional Gels Demonstrate Inefficient Replication Origin Usage. Molecular and Cellular Biology 16:9, pages 4915-4922.
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Articles from other publishers (19)

Tricia J Cluett, Gokhan Akman, Aurelio Reyes, Lawrence Kazak, Alice Mitchell, Stuart R Wood, Antonella Spinazzola, Johannes N Spelbrink & Ian J Holt. (2018) Transcript availability dictates the balance between strand-asynchronous and strand-coupled mitochondrial DNA replication. Nucleic Acids Research.
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Nataliya Petryk, Malik Kahli, Yves d'Aubenton-Carafa, Yan Jaszczyszyn, Yimin Shen, Maud Silvain, Claude Thermes, Chun-Long Chen & Olivier Hyrien. (2016) Replication landscape of the human genome. Nature Communications 7:1.
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Larry D. Mesner, Veena Valsakumar, Marcin Cieślik, Rebecca Pickin, Joyce L. Hamlin & Stefan Bekiranov. (2013) Bubble-seq analysis of the human genome reveals distinct chromatin-mediated mechanisms for regulating early- and late-firing origins. Genome Research 23:11, pages 1774-1788.
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Aurelio Reyes, Lawrence Kazak, Stuart R. Wood, Takehiro Yasukawa, Howard T. Jacobs & Ian J. Holt. (2013) Mitochondrial DNA replication proceeds via a ‘bootlace’ mechanism involving the incorporation of processed transcripts. Nucleic Acids Research 41:11, pages 5837-5850.
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Larry D. Mesner, Veena Valsakumar, Neerja Karnani, Anindya Dutta, Joyce L. Hamlin & Stefan Bekiranov. (2011) Bubble-chip analysis of human origin distributions demonstrates on a genomic scale significant clustering into zones and significant association with transcription. Genome Research 21:3, pages 377-389.
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Jennifer Reineke Pohlhaus & Kenneth N. Kreuzer. 2006. DNA Repair, Part B. DNA Repair, Part B 477 493 .
H.-B. Lin, P.A. Dijkwel & J.L. Hamlin. (2005) Promiscuous initiation on mammalian chromosomal DNA templates and its possible suppression by transcription. Experimental Cell Research 308:1, pages 53-64.
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Takehiro Yasukawa, Ming-Yao Yang, Howard T. Jacobs & Ian J. Holt. (2005) A Bidirectional Origin of Replication Maps to the Major Noncoding Region of Human Mitochondrial DNA. Molecular Cell 18:6, pages 651-662.
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Mark Bowmaker, Ming Yao Yang, Takehiro Yasukawa, Aurelio Reyes, Howard T. Jacobs, Joel A. Huberman & Ian J. Holt. (2003) Mammalian Mitochondrial DNA Replicates Bidirectionally from an Initiation Zone. Journal of Biological Chemistry 278:51, pages 50961-50969.
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D. H. Williamson, P. R. Preiser, P. W. Moore, S. McCready, M. Strath & R. J. M. (Iain) Wilson. (2002) The plastid DNA of the malaria parasite Plasmodium falciparum is replicated by two mechanisms. Molecular Microbiology 45:2, pages 533-542.
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Paolo NorioCarl L. Schildkraut. (2001) Visualization of DNA Replication on Individual Epstein-Barr Virus Episomes. Science 294:5550, pages 2361-2364.
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Lucy Lu, Hongjun Zhang & John Tower. (2001) Functionally distinct, sequence-specific replicator and origin elements are required for Drosophila chorion gene amplification . Genes & Development 15:2, pages 134-146.
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Cong-Jun Li, Joseph A. Bogan, Darren A. Natale & Melvin L. DePamphilis. (2000) Selective activation of pre-replication complexes in vitro at specific sites in mammalian nuclei. Journal of Cell Science 113:5, pages 887-898.
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Pieter A. Dijkwel & Joyce L. Hamlin. (1999) Physical and Genetic Mapping of Mammalian Replication Origins. Methods 18:3, pages 418-431.
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R.F Kalejta, X Li, L.D Mesner, P.A Dijkwel, H.-B Lin & J.L Hamlin. (1998) Distal Sequences, but Not ori-β/OBR-1, Are Essential for Initiation of DNA Replication in the Chinese Hamster DHFR Origin. Molecular Cell 2:6, pages 797-806.
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F. Toledo, B. Baron, M.-A. Fernandez, A.-M. Lachages, V. Mayau, G. Buttin & M. Debatisse. (1998) oriGNAI3: A narrow zone of preferential replication initiation in mammalian cells identified by 2D gel and competitive PCR replicon mapping techniques. Nucleic Acids Research 26:10, pages 2313-2321.
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David M Gilbert. (1998) Replication origins in yeast versus metazoa: separation of the haves and the have nots. Current Opinion in Genetics & Development 8:2, pages 194-199.
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Joel A Huberman. (1997) Mapping Replication Origins, Pause Sites, and Termini by Neutral/Alkaline Two-Dimensional Gel Electrophoresis. Methods 13:3, pages 247-257.
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Peter A. Dijkwel & Joyce L. Hamlin. (1997) Mapping Replication Origins by Neutral/Neutral Two-Dimensional Gel Electrophoresis. Methods 13:3, pages 235-245.
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