Advanced search
Publication Cover
Molecular and Cellular Biology Volume 17, 1997 - Issue 12
Submit an article Journal homepage
6
Views
19
CrossRef citations to date
0
Altmetric
Research Article

RAG-1 and RAG-2-Dependent Assembly of Functional Complexes with V(D)J Recombination Substrates in Solution

Wenhui LiDepartment of Molecular Biology and Genetics and Howard Hughes Medical Institute, The Johns Hopkins University School of Medicine, Baltimore, Maryland21205
,
Patrick SwansonDepartment of Molecular Biology and Genetics and Howard Hughes Medical Institute, The Johns Hopkins University School of Medicine, Baltimore, Maryland21205
&
Stephen DesiderioDepartment of Molecular Biology and Genetics and Howard Hughes Medical Institute, The Johns Hopkins University School of Medicine, Baltimore, Maryland21205
Pages 6932-6939 | Received 07 Jul 1997, Accepted 03 Sep 1997, Published online: 29 Mar 2023

Citations (19)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (8)

Aleksei N. Kriatchko, Dirk K. Anderson & Patrick C. Swanson. (2006) Identification and Characterization of a Gain-of-Function RAG-1 Mutant. Molecular and Cellular Biology 26:12, pages 4712-4728.
Read now
Leslie E. Huye, Mary M. Purugganan, Ming-Ming Jiang & David B. Roth. (2002) Mutational Analysis of All Conserved Basic Amino Acids in RAG-1 Reveals Catalytic, Step Arrest, and Joining-Deficient Mutants in the V(D)J Recombinase. Molecular and Cellular Biology 22:10, pages 3460-3473.
Read now
Patrick C. Swanson. (2002) Fine Structure and Activity of Discrete RAG-HMG Complexes on V(D)J Recombination Signals. Molecular and Cellular Biology 22:5, pages 1340-1351.
Read now
Mark A. Landree, Sam B. Kale & David B. Roth. (2001) Functional Organization of Single and Paired V(D)J Cleavage Complexes. Molecular and Cellular Biology 21:13, pages 4256-4264.
Read now
Wenhui Li, Fu-Chung Chang & Stephen Desiderio. (2001) RAG-1 Mutations Associated with B-Cell-Negative SCID Dissociate the Nicking and Transesterification Steps of V(D)J Recombination. Molecular and Cellular Biology 21:12, pages 3935-3946.
Read now
Patrick C. Swanson. (2001) The DDE Motif in RAG-1 Is Contributed in trans to a Single Active Site That Catalyzes the Nicking and Transesterification Steps of V(D)J Recombination. Molecular and Cellular Biology 21:2, pages 449-458.
Read now
Quinn M. Eastman, Isabelle J. Villey & David G. Schatz. (1999) Detection of RAG Protein-V(D)J Recombination Signal Interactions Near the Site of DNA Cleavage by UV Cross-Linking. Molecular and Cellular Biology 19:5, pages 3788-3797.
Read now
Patrick C. Swanson & Stephen Desiderio. (1999) RAG-2 Promotes Heptamer Occupancy by RAG-1 in the Assembly of a V(D)J Initiation Complex. Molecular and Cellular Biology 19:5, pages 3674-3683.
Read now

Articles from other publishers (11)

Mikalai Lapkouski, Watchalee Chuenchor, Min-Sung Kim, Martin Gellert & Wei Yang. (2015) Assembly Pathway and Characterization of the RAG1/2-DNA Paired and Signal-end Complexes. Journal of Biological Chemistry 290:23, pages 14618-14625.
Crossref
Serge Bergeron, Tina Madathiparambil & Patrick C. Swanson. (2005) Both High Mobility Group (HMG)-boxes and the Acidic Tail of HMGB1 Regulate Recombination-activating Gene (RAG)-mediated Recombination Signal Synapsis and Cleavage in Vitro. Journal of Biological Chemistry 280:35, pages 31314-31324.
Crossref
Patrick C. Swanson. (2004) The bounty of RAGs: recombination signal complexes and reaction outcomes. Immunological Reviews 200:1, pages 90-114.
Crossref
Patrick C. Swanson, Dustin Volkmer & Lei Wang. (2004) Full-length RAG-2, and Not Full-length RAG-1, Specifically Suppresses RAG-mediated Transposition but Not Hybrid Joint Formation or Disintegration. Journal of Biological Chemistry 279:6, pages 4034-4044.
Crossref
JOANN SEKIGUCHI, FREDERICK W. ALT & MARJORIE OETTINGER. 2004. Molecular Biology of B Cells. Molecular Biology of B Cells 61 82 .
Mihai Ciubotaru, Leon M. Ptaszek, Gary A. Baker, Sheila N. Baker, Frank V. Bright & David G. Schatz. (2003) RAG1-DNA Binding in V(D)J Recombination. Journal of Biological Chemistry 278:8, pages 5584-5596.
Crossref
Vijaya B. Kumar, Mark W. Franko, Susan A. Farr, H.James Armbrecht & John E. Morley. (2000) Identification of Age-Dependent Changes in Expression of Senescence-Accelerated Mouse (SAMP8) Hippocampal Proteins by Expression Array Analysis. Biochemical and Biophysical Research Communications 272:3, pages 657-661.
Crossref
Anton Tevelev & David G. Schatz. (2000) Intermolecular V(D)J Recombination. Journal of Biological Chemistry 275:12, pages 8341-8348.
Crossref
S. Desiderio & J. Lee. 2000. Signal Transduction and the Coordination of B Lymphocyte Development and Function II. Signal Transduction and the Coordination of B Lymphocyte Development and Function II 31 56 .
Eva Besmer, Jorge Mansilla-Soto, Sylvanie Cassard, Dennis J Sawchuk, Greg Brown, Moshe Sadofsky, Susanna M Lewis, Michel C Nussenzweig & Patricia Cortes. (1998) Hairpin Coding End Opening Is Mediated by RAG1 and RAG2 Proteins. Molecular Cell 2:6, pages 817-828.
Crossref
Patrick C. Swanson & Stephen Desiderio. (1998) V(D)J Recombination Signal Recognition. Immunity 9:1, pages 115-125.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.