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Research Article

Complex Formation between p53 and Replication Protein A Inhibits the Sequence-Specific DNA Binding of p53 and Is Regulated by Single-Stranded DNA

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Pages 2194-2201 | Received 25 Oct 1996, Accepted 27 Dec 1996, Published online: 29 Mar 2023

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Colleen C. Caldwell & Maria Spies. (2020) Dynamic elements of replication protein A at the crossroads of DNA replication, recombination, and repair. Critical Reviews in Biochemistry and Molecular Biology 55:5, pages 482-507.
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Karen E. Sukhodolets, Alison B. Hickman, Sunita K. Agarwal, Maxim V. Sukhodolets, Victor H. Obungu, Elizabeth A. Novotny, Judy S. Crabtree, Settara C. Chandrasekharappa, Francis S. Collins, Allen M. Spiegel, A. Lee Burns & Stephen J. Marx. (2003) The 32-Kilodalton Subunit of Replication Protein A Interacts with Menin, the Product of the MEN1 Tumor Suppressor Gene. Molecular and Cellular Biology 23:2, pages 493-509.
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Shrikanth P. Hegde, Alok Kumar, Cornelia Kurschner & Linda H. Shapiro. (1998) c-Maf Interacts with c-Myb To Regulate Transcription of an Early Myeloid Gene during Differentiation. Molecular and Cellular Biology 18:5, pages 2729-2737.
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Mary E. Anderson, Birgit Woelker, Michael Reed, Pin Wang & Peter Tegtmeyer. (1997) Reciprocal Interference between the Sequence-Specific Core and Nonspecific C-Terminal DNA Binding Domains of p53: Implications for Regulation. Molecular and Cellular Biology 17:11, pages 6255-6264.
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Articles from other publishers (30)

Stephanie Biber, Helmut Pospiech, Vanesa Gottifredi & Lisa Wiesmüller. (2020) Multiple biochemical properties of the p53 molecule contribute to activation of polymerase iota-dependent DNA damage tolerance. Nucleic Acids Research 48:21, pages 12188-12203.
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Mark Hedglin, Mahesh Aitha, Anthony Pedley & Stephen J. Benkovic. (2019) Replication protein A dynamically regulates monoubiquitination of proliferating cell nuclear antigen. Journal of Biological Chemistry 294:13, pages 5157-5168.
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Yuesheng Zhu, Yongdong Yi, Binglong Bai, Liyi Li, Tao You, Weijian Sun & Yaojun Yu. (2018) The silencing of replication protein A1 induced cell apoptosis via regulating Caspase 3. Life Sciences 201, pages 141-149.
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M A Serrano, Z Li, M Dangeti, P R Musich, S Patrick, M Roginskaya, B Cartwright & Y Zou. (2012) DNA-PK, ATM and ATR collaboratively regulate p53–RPA interaction to facilitate homologous recombination DNA repair. Oncogene 32:19, pages 2452-2462.
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Jason G. Glanzer, Katie A. Carnes, Patricia Soto, Shengqin Liu, Lawrence J. Parkhurst & Gregory G. Oakley. (2013) A small molecule directly inhibits the p53 transactivation domain from binding to replication protein A. Nucleic Acids Research 41:3, pages 2047-2059.
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Gaofeng JiangYue ZouXiaoming Wu. (2013) Replication‐mediated disassociation of replication protein A—XPA complex upon DNA damage: implications for RPA handing off. Cell Biology International 36:8, pages 713-720.
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Chukwudi Ezeokonkwo, Alexander Zhelkovsky, Rosanna Lee, Andrew Bohm & Claire L. Moore. (2011) A flexible linker region in Fip1 is needed for efficient mRNA polyadenylation. RNA 17:4, pages 652-664.
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Joseph Shlomai. (2010) Redox Control of Protein–DNA Interactions: From Molecular Mechanisms to Significance in Signal Transduction, Gene Expression, and DNA Replication. Antioxidants & Redox Signaling 13:9, pages 1429-1476.
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Kengo Sakaguchi, Toyotaka Ishibashi, Yukinobu Uchiyama & Kazuki Iwabata. (2009) The multi-replication protein A (RPA) system - a new perspective. FEBS Journal 276:4, pages 943-963.
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Nikolaos Givalos, Hariklia Gakiopoulou, Melina Skliri, Katerina Bousboukea, Anastasia E Konstantinidou, Penelope Korkolopoulou, Maria Lelouda, Gregory Kouraklis, Efstratios Patsouris & Gabriel Karatzas. (2007) Replication protein A is an independent prognostic indicator with potential therapeutic implications in colon cancer. Modern Pathology 20:2, pages 159-166.
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Sangaralingam Kumaran, Alexander G. Kozlov & Timothy M. Lohman. (2006) Saccharomyces cerevisiae Replication Protein A Binds to Single-Stranded DNA in Multiple Salt-Dependent Modes . Biochemistry 45:39, pages 11958-11973.
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S A Gatz & L Wiesmüller. (2006) p53 in recombination and repair. Cell Death & Differentiation 13:6, pages 1003-1016.
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Elena BochkarevaLilia KaustovAyeda AyedGwan-Su YiYing LuAntonio Pineda-LucenaJack C. C. LiaoAndrei L. OkorokovJo MilnerCheryl H. ArrowsmithAlexey Bochkarev. (2005) Single-stranded DNA mimicry in the p53 transactivation domain interaction with replication protein A. Proceedings of the National Academy of Sciences 102:43, pages 15412-15417.
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Yueh-Ming Loo & Thomas Melendy. (2004) Recruitment of Replication Protein A by the Papillomavirus E1 Protein and Modulation by Single-Stranded DNA. Journal of Virology 78:4, pages 1605-1615.
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Oliver Schmitt, Christine Schubert, Thomas Feyerabend, Thomas Hellwig-Bürgel, Christoph Weiss & Wolfgang Kühnel. (2002) Preferential Topography of Proteins Regulating Vascularization and Apoptosis in a MX1 Xenotransplant After Treatment With Hypoxia, Hyperthermia, Ifosfamide, and Irradiation. American Journal of Clinical Oncology 25:4, pages 325-336.
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Jaroslaw Dziegielewski & Terry A. Beerman. (2002) Cellular Responses to the DNA Strand-scission Enediyne C-1027 Can Be Independent of ATM, ATR, and DNA-PK Kinases. Journal of Biological Chemistry 277:23, pages 20549-20554.
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Gregory G. Oakley, Lisa I. Loberg, Jiaqin Yao, Mary A. Risinger, Remy L. Yunker, Maria Zernik-Kobak, Kum Kum Khanna, Martin F. Lavin, Michael P. Carty & Kathleen Dixon. (2001) UV-induced Hyperphosphorylation of Replication Protein A Depends on DNA Replication and Expression of ATM Protein. Molecular Biology of the Cell 12:5, pages 1199-1213.
Crossref
Giovanni Maga, Isabelle Frouin, Silvio Spadari & Ulrich Hübscher. (2001) Replication Protein A as a “Fidelity Clamp” for DNA Polymerase α. Journal of Biological Chemistry 276:21, pages 18235-18242.
Crossref
Marc S Wold. 2001. eLS. eLS.
Hagai Offer, Michael Milyavsky, Neta Erez, Devorah Matas, Irit Zurer, Curtis C Harris & Varda Rotter. (2001) Structural and functional involvement of p53 in BER in vitro and in vivo. Oncogene 20:5, pages 581-589.
Crossref
Theresa Allio, E.Maria Donner & R.Julian Preston. (2000) A comparison of the roles of p53 mutation and AraC inhibition in the enhancement of bleomycin-induced chromatid aberrations in mouse and human cells. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 447:2, pages 227-237.
Crossref
Jen-Sing Liu, Shu-Ru Kuo, Mary M. McHugh, Terry A. Beerman & Thomas Melendy. (2000) Adozelesin Triggers DNA Damage Response Pathways and Arrests SV40 DNA Replication through Replication Protein A Inactivation. Journal of Biological Chemistry 275:2, pages 1391-1397.
Crossref
F. Fernández-Madrid & J. Tomkiel. 2000. Cancer and Autoimmunity. Cancer and Autoimmunity 151 158 .
Chantal Courtemanche & Alan Anderson. (1999) Multiple mutations in a shuttle vector modified by ultraviolet irradiation, (±)-7β,8α-dihydroxy-9α,10α-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene, and aflatoxin B1 have different properties than single mutations and may be generated during translesion synthesis. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 430:1, pages 23-36.
Crossref
Kurt W. Kohn. (1999) Molecular Interaction Map of the Mammalian Cell Cycle Control and DNA Repair Systems. Molecular Biology of the Cell 10:8, pages 2703-2734.
Crossref
Hagai Offer, Roland Wolkowicz, Devorah Matas, Sara Blumenstein, Zvi Livneh & Varda Rotter. (1999) Direct involvement of p53 in the base excision repair pathway of the DNA repair machinery. FEBS Letters 450:3, pages 197-204.
Crossref
Isabelle Salles-Passador, Arun Fotedar & Rati Fotedara. (1999) Cellular response to DNA damage. Link between p53 and DNA-PK. Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie 322:2-3, pages 113-120.
Crossref
Elizabeth A. Fortunato & Deborah H. Spector. 1999. 61 128 .
Elizabeth A. Fortunato & Deborah H. Spector. (1998) p53 and RPA Are Sequestered in Viral Replication Centers in the Nuclei of Cells Infected with Human Cytomegalovirus. Journal of Virology 72:3, pages 2033-2039.
Crossref
Natalia A. Abramova, Jackie Russell, Michael Botchan & Rong Li. (1997) Interaction between replication protein A and p53 is disrupted after UV damage in a DNA repair-dependent manner. Proceedings of the National Academy of Sciences 94:14, pages 7186-7191.
Crossref

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