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Transcriptional Regulation

DDB, a Putative DNA Repair Protein, Can Function as a Transcriptional Partner of E2F1

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Pages 240-249 | Received 17 Sep 1997, Accepted 23 Oct 1997, Published online: 28 Mar 2023

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Swarnalatha Manickavinayaham, Renier Velez-Cruz, Anup K. Biswas, Jie Chen, Ruifeng Guo & David G. Johnson. (2020) The E2F1 transcription factor and RB tumor suppressor moonlight as DNA repair factors. Cell Cycle 19:18, pages 2260-2269.
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Paola Perucca, Sabrina Sommatis, Roberto Mocchi, Ennio Prosperi, Lucia Anna Stivala & Ornella Cazzalini. (2015) A DDB2 mutant protein unable to interact with PCNA promotes cell cycle progression of human transformed embryonic kidney cells. Cell Cycle 14:24, pages 3920-3928.
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Martha Rodriguez Sandoval, Kumudha Balakrishnan, Rajyalakshmi Luthra, Michael Keating & Varsha Gandhi. (2014) DNA repair initiation induces expression of ribonucleotide reductase in human chronic lymphocytic leukemia cells. Leukemia & Lymphoma 55:4, pages 876-883.
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Ling Zhang, Abigail Lubin, Hua Chen, Zhongyi Sun & Feng Gong. (2012) The deubiquitinating protein USP24 interacts with DDB2 and regulates DDB2 stability. Cell Cycle 11:23, pages 4378-4384.
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Li-Chung Hsu, Shu Liu, Ferishteh Abedinpour, Robert D. Beech, Jill M. Lahti, Vincent J. Kidd, Jeffrey A. Greenspan & Cho-Yau Yeung. (2003) The Murine G+C-Rich Promoter Binding Protein mGPBP Is Required for Promoter-Specific Transcription. Molecular and Cellular Biology 23:23, pages 8773-8785.
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Abhishek Datta, Alo Nag & Pradip Raychaudhuri. (2002) Differential Regulation of E2F1, DP1, and the E2F1/DP1 Complex by ARF. Molecular and Cellular Biology 22:24, pages 8398-8408.
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Ernest Martinez, Vikas B. Palhan, Agneta Tjernberg, Elena S. Lymar, Armin M. Gamper, Tapas K. Kundu, Brian T. Chait & Robert G. Roeder. (2001) Human STAGA Complex Is a Chromatin-Acetylating Transcription Coactivator That Interacts with Pre-mRNA Splicing and DNA Damage-Binding Factors In Vivo. Molecular and Cellular Biology 21:20, pages 6782-6795.
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Alo Nag, Tanya Bondar, Shalu Shiv & Pradip Raychaudhuri. (2001) The Xeroderma Pigmentosum Group E Gene Product DDB2 Is a Specific Target of Cullin 4A in Mammalian Cells. Molecular and Cellular Biology 21:20, pages 6738-6747.
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Ryujiro Hara, Jinyao Mo & Aziz Sancar. (2000) DNA Damage in the Nucleosome Core Is Refractory to Repair by Human Excision Nuclease. Molecular and Cellular Biology 20:24, pages 9173-9181.
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Pavel Shiyanov, Steven A. Hayes, Manjula Donepudi, Anne F. Nichols, Stuart Linn, Betty L. Slagle & Pradip Raychaudhuri. (1999) The Naturally Occurring Mutants of DDB Are Impaired in Stimulating Nuclear Import of the p125 Subunit and E2F1-Activated Transcription. Molecular and Cellular Biology 19:7, pages 4935-4943.
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Julie Dardare, Andréa Witz, Margaux Betz, Aurélie Francois, Morgane Meras, Laureline Lamy, Aurélien Lambert, Stéphanie Grandemange, Marie Husson, Marie Rouyer, Jessica Demange, Jean-Louis Merlin, Alexandre Harlé & Pauline Gilson. (2022) DDB2 represses epithelial-to-mesenchymal transition and sensitizes pancreatic ductal adenocarcinoma cells to chemotherapy. Frontiers in Oncology 12.
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Xu Wang, Hao-Yan Wang, Guo-Sheng Hu, Wen-Shuai Tang, Li Weng, Yuzhu Zhang, Huiling Guo, Shan-Shan Yao, Shen-Ying Liu, Guo-Liang Zhang, Yan Han, Min Liu, Xiao-Dong Zhang, Xiang Cen, Hai-Feng Shen, Nengming Xiao, Chang-Qin Liu, Hong-Rui Wang, Jing Huang, Wen Liu, Peng Li & Tong-Jin Zhao. (2021) DDB1 binds histone reader BRWD3 to activate the transcriptional cascade in adipogenesis and promote onset of obesity. Cell Reports 35:12, pages 109281.
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Hongliang LiuZhensheng LiuYanru WangThomas E. StinchcombeKouros OwzarYounghun HanRayjean J. HungYonathan BrhaneJohn McLaughlinPaul BrennanHeike BickeböllerAlbert RosenbergerRichard S. HoulstonNeil CaporasoMaria T. LandiIrene BrüskeAngela RischXifeng WuYuanqing YeDavid C. Christiani, Christopher I. AmosQingyi Wei. (2017) Functional variants in DCAF4 associated with lung cancer risk in European populations. Carcinogenesis 38:5, pages 541-551.
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James E. Cleaver. 2017. The Molecular Basis of Human Cancer. The Molecular Basis of Human Cancer 363 380 .
Woohyun Kim, Sooyoung Lee, Yeongnam Son, Chunkyu Ko & Wang-Shick Ryu. (2016) DDB1 Stimulates Viral Transcription of Hepatitis B Virus via HBx-Independent Mechanisms. Journal of Virology 90:21, pages 9644-9653.
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Massimo Mangino, Lene Christiansen, Rivka Stone, Steven C Hunt, Kent Horvath, Dan T A Eisenberg, Masayuki Kimura, Inge Petersen, Jeremy D Kark, Utz Herbig, Alex P Reiner, Athanase Benetos, Veryan Codd, Dale R Nyholt, Ronit Sinnreich, Kaare Christensen, Hisham Nassar, Shih-Jen Hwang, Daniel Levy, Veronique Bataille, Annette L Fitzpatrick, Wei Chen, Gerald S Berenson, Nilesh J Samani, Nicholas G Martin, Sarah Tishkoff, Nicholas J Schork, Kirsten Ohm Kyvik, Christine Dalgård, Timothy D Spector & Abraham Aviv. (2015) DCAF4 , a novel gene associated with leucocyte telomere length . Journal of Medical Genetics 52:3, pages 157-162.
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Kristi L. Jones, Ling Zhang, Kenneth L. Seldeen & Feng Gong. (2010) Detection of bulky DNA lesions: DDB2 at the interface of chromatin and DNA repair in eukaryotes. IUBMB Life 62:11, pages 803-811.
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Ruifeng Guo, Jie Chen, Feng Zhu, Anup K. Biswas, Thomas R. Berton, David L. Mitchell & David G. Johnson. (2010) E2F1 Localizes to Sites of UV-induced DNA Damage to Enhance Nucleotide Excision Repair. Journal of Biological Chemistry 285:25, pages 19308-19315.
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Tanya Bondar, Aleksandr Ponomarev & Pradip Raychaudhuri. (2004) Ddb1 Is Required for the Proteolysis of the Schizosaccharomyces pombe Replication Inhibitor Spd1 during S Phase and after DNA Damage. Journal of Biological Chemistry 279:11, pages 9937-9943.
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